Ticlopidine Platelets And Vascular Disease

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Ticlopidine, Platelets and Vascular Disease

William K. Hass,J.Donald Easton
Ticlopidine Platelets and Vascular Disease Book PDF

Author : William K. Hass,J.Donald Easton
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461383062

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Ticlopidine, Platelets and Vascular Disease by William K. Hass,J.Donald Easton Pdf

Blood platelets lack a nucleus. As a result their life span is short and they cannot reproduce themselves. Platelets share these qualities with the red blood cell. Plate lets and red blood cells, nevertheless, serve vital roles in the body. One major function of the platelet is its capacity to aggregate and thereby initiate intravas cular coagulation which often underlies such major diseases as myocardial infarc tion, cerebral infarction, and pulmonary embolism. For this reason in recent years, medical attention has been directed to drugs that inhibit platelet aggregation. Aspirin was the first drug to be proven effective in this area. Since then other drugs that share aspirin's fundamental biochemical action, inhibition of platelet cyclooxygenase, have also been studied. Very recently, ticlopidine, the first of what promises to be a new class of drugs inhibiting platelet aggregation and coagulation via an entirely different biochemical mechanism, has been exten sively studied and clinically shown to be as effective or more effective than aspirin in the prevention of ischemic cardiovascular and cerebrovascular disease.

Platelets in Cardiovascular Disease

Deepak L. Bhatt
Platelets in Cardiovascular Disease Book PDF

Author : Deepak L. Bhatt
Publisher : Imperial College Press
Page : 235 pages
File Size : 47,5 Mb
Release : 2008
Category : Medical
ISBN : 9781860948268

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Platelets in Cardiovascular Disease by Deepak L. Bhatt Pdf

Platelets in Cardiovascular Disease provides an in-depth and current coverage of relevant platelet biology and antiplatelet therapy that is in clinical use today and potentially for the future. The book provides a succinct overview of the critical role of platelets in cardiovascular medicine.Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells. This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease.Drawing upon a panel of international experts, Platelets in Cardiovascular Disease delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful.

Mechanisms of Vascular Disease

Robert Fitridge,M. M. Thompson
Mechanisms of Vascular Disease Book PDF

Author : Robert Fitridge,M. M. Thompson
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 41,7 Mb
Release : 2011
Category : Medical
ISBN : 9781922064004

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Mechanisms of Vascular Disease by Robert Fitridge,M. M. Thompson Pdf

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease

A. Michael Lincoff
Platelet Glycoprotein IIb IIIa Inhibitors in Cardiovascular Disease Book PDF

Author : A. Michael Lincoff
Publisher : Springer Science & Business Media
Page : 415 pages
File Size : 43,6 Mb
Release : 1999-03-04
Category : Medical
ISBN : 9781592597246

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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease by A. Michael Lincoff Pdf

In Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease, the major investigators working in this rapidly advancing field join together under the aegis of A. Michael Lincoff and Eric J. Topol to provide the first comprehensive overview of the preclinical and clinical development of the glycoprotein IIb/IIIa receptor antagonists. These acknowledged experts elucidate the theoretical basis for the inhibition of platelet aggregation in the treatment of coronary syndromes, present and synthesize evidence for the efficacy of glycoprotein IIb/IIIa blockade in inhibiting ischemic complications of both coronary intervention and acute coronary syndromes, and provide guidelines for the use of this novel class of agents in the clinical management of cardiovascular disease. They also compare the pharmacology and clinical efficacy of the currently available glycoprotein IIb/IIIa receptor inhibitors and speculate about further potential applications of these agents in the treatment of vascular disease. Written by the scientists and physicians who discovered and characterized this important new class of receptors, invented the first IIb/IIIa agents, and conducted the definitive clinical trials, Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease offers the most complete and authoritative review of these powerful new therapeutics available today.

Drug Therapy for Stroke Prevention

Julian Bogousslavsky
Drug Therapy for Stroke Prevention Book PDF

Author : Julian Bogousslavsky
Publisher : CRC Press
Page : 316 pages
File Size : 43,5 Mb
Release : 2003-09-02
Category : Medical
ISBN : 9780203211410

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Drug Therapy for Stroke Prevention by Julian Bogousslavsky Pdf

Stroke is the third leading cause of death in the USA and UK. It is a major cause of disability among adults and is a significant factor in dementia in later life and its incidence is on the rise. This book discusses specific medications that target the blood and vasculature and how these treatments can be used to complement other therapeutic measures, such as carotid endarterectomy. It covers the pharmacological methods used to address the risk factors in stroke, the major drug discoveries of recent years--antiaggregant, antithrombotic, and anticoagulant therapies--and also long established therapies such as aspirin and warfarin. With contributions by internationally recognized experts, this is a unique single source of information on current pharmacological prevention of stroke.

Stroke in Blacks

Richard F. Gillum,Philip B. Gorelick,Edward S. Cooper
Stroke in Blacks Book PDF

Author : Richard F. Gillum,Philip B. Gorelick,Edward S. Cooper
Publisher : Karger Medical and Scientific Publishers
Page : 242 pages
File Size : 53,9 Mb
Release : 1999
Category : Medical
ISBN : 9783805567138

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Stroke in Blacks by Richard F. Gillum,Philip B. Gorelick,Edward S. Cooper Pdf

This is an excellent, easily perused book that will be useful to anyone interested in stroke in general and in blacks specifically. The importance of primary prevention is a message that emerges resoundingly.

Carotid Artery Stenosis

Seemant Chaturvedi,Peter M. Rothwell
Carotid Artery Stenosis Book PDF

Author : Seemant Chaturvedi,Peter M. Rothwell
Publisher : CRC Press
Page : 392 pages
File Size : 51,9 Mb
Release : 2005-07-28
Category : Medical
ISBN : 9781135534745

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Carotid Artery Stenosis by Seemant Chaturvedi,Peter M. Rothwell Pdf

Providing a thorough overview of rapid developments in medical therapy, surgery, and angioplasty, this reference provides a complete review of carotid artery stenosis treatment, as well as a clear overview of carotid surgery and stenting. Offering chapters by seasoned authorities on epidemiology, imaging with ultrasound and angiography, cholesterol

Platelets in Hematologic and Cardiovascular Disorders

Paolo Gresele,Valentin Fuster,Jose A. Lopez,Clive P. Page,Jos Vermylen
Platelets in Hematologic and Cardiovascular Disorders Book PDF

Author : Paolo Gresele,Valentin Fuster,Jose A. Lopez,Clive P. Page,Jos Vermylen
Publisher : Cambridge University Press
Page : 483 pages
File Size : 50,5 Mb
Release : 2007-12-13
Category : Medical
ISBN : 9781139468763

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Platelets in Hematologic and Cardiovascular Disorders by Paolo Gresele,Valentin Fuster,Jose A. Lopez,Clive P. Page,Jos Vermylen Pdf

A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions. This text focuses on the clinical role of platelets in a wide variety of haematologic, cardiovascular and other disorders, providing a practical, clinically relevant handbook for all clinicians and researchers interested in platelets and their role in disease. Covering platelet physiology, bleeding disorders, thrombotic disorders and antithrombotic therapy. Chapters cover all the conventional and less conventional aspects of platelet involvement in disease, with an emphasis on recent clinical developments. Clear take home messages have been included in each chapter to aid clinical practice. With contributions from leading experts across three continents, Platelets in Hematologic and Cardiovascular Disorders is an up-to-date, well illustrated, practical resource for everyone involved in clinical practice with platelet disorders.

Side Effects of Drugs Annual

Jeffrey K. Aronson
Side Effects of Drugs Annual Book PDF

Author : Jeffrey K. Aronson
Publisher : Elsevier
Page : 715 pages
File Size : 46,7 Mb
Release : 2011-08-19
Category : Medical
ISBN : 9780080522814

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Side Effects of Drugs Annual by Jeffrey K. Aronson Pdf

The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has contributed to the Annuals by selecting critically from each year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is misleading. Provides a critical yearly survey of new data and trends Includes an essay that describes the modern approach to classifying adverse drug reactions Special reviews in this Annual include, among other topics: Antipsychotic drugs and now-onset diabetes mellitus, Treating asthma during pregnancy, and MMR vaccine and autism

Practical Cardiology

Majid Maleki,Azin Alizadehasl,Majid Haghjoo
Practical Cardiology Book PDF

Author : Majid Maleki,Azin Alizadehasl,Majid Haghjoo
Publisher : Elsevier Health Sciences
Page : 400 pages
File Size : 46,6 Mb
Release : 2017-08-25
Category : Medical
ISBN : 9780323511766

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Practical Cardiology by Majid Maleki,Azin Alizadehasl,Majid Haghjoo Pdf

From basic clinical facts to new advanced guidelines, Practical Cardiology, by Drs. Majid Maleki, Azin Alizadehasl, and Majid Haghjoo, is your new go-to resource for new developments in cardiology knowledge, imaging modalities, management techniques, and more. This step-by-step, practical reference is packed with tips and guidance ideal for residents, fellows, and clinicians in cardiology, as well as internal medicine, cardiac surgery, interventional cardiology, and pediatric cardiology. Features a wealth of information, including practical points from recently published guidelines, ECGs, hemodynamic traces of advanced imaging modalities in real patients, and much more. Offers a comprehensive review of cardiovascular medicine, from basic to advanced.

Peripheral Vascular Disease

George S. Abela
Peripheral Vascular Disease Book PDF

Author : George S. Abela
Publisher : Lippincott Williams & Wilkins
Page : 570 pages
File Size : 53,6 Mb
Release : 2004
Category : Medical
ISBN : 0781743834

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Peripheral Vascular Disease by George S. Abela Pdf

"Abela (cardiology, Michigan State University) provides guidelines for recognizing and treating all types of peripheral vascular disease (PVD), combining a multidisciplinary perspective with information on the latest developments. Early chapters cover anatomy, etiology, and symptoms, and later chapters detail treatment with drugs, exercise, and anticoagulants. Diagnostic chapters describe various methods for testing and imaging, and surgical chapters outline pre-and post- operative management and look at stent grafts for various conditions. Final chapters describe technical training requirements for practice and credentialing, and address billing and coding issues. B&w medical images and surgical photos are included. Annotation: 2004 Book News, Inc., Portland, OR (booknews.com)"--[source inconnue].

Platelets

Alan D. Michelson
Platelets Book PDF

Author : Alan D. Michelson
Publisher : Elsevier
Page : 1386 pages
File Size : 48,8 Mb
Release : 2011-08-29
Category : Medical
ISBN : 9780080465869

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Platelets by Alan D. Michelson Pdf

Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. First edition won Best Book in Medical Science Award from the Association of American Publishers Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references

Anesthetic Pharmacology

Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Anesthetic Pharmacology Book PDF

Author : Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publisher : Cambridge University Press
Page : 2902 pages
File Size : 49,7 Mb
Release : 2011-03-10
Category : Medical
ISBN : 9781139497022

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Anesthetic Pharmacology by Alex S. Evers,Mervyn Maze,Evan D. Kharasch Pdf

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Mechanisms of Vascular Disease

Robert Fitridge
Mechanisms of Vascular Disease Book PDF

Author : Robert Fitridge
Publisher : Springer Nature
Page : 739 pages
File Size : 49,8 Mb
Release : 2020-07-30
Category : Medical
ISBN : 9783030436834

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Mechanisms of Vascular Disease by Robert Fitridge Pdf

This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic.

Blood Platelets

Meinrad Gawaz
Blood Platelets Book PDF

Author : Meinrad Gawaz
Publisher : Georg Thieme Verlag
Page : 204 pages
File Size : 50,8 Mb
Release : 2001
Category : Medical
ISBN : 3131058110

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Blood Platelets by Meinrad Gawaz Pdf

This book provides a comprehensive survey of the importance of blood platelets for coronary heart diseases. It gives both research workers and clinicians an insight into the function of thrombocytes and the significance of platelets in the clinical framework of coronary heart diseases in order to create an understanding of the differntiated use of antithrombocytic principles. The first part is dedicated to the function of platelets hemostasis and their connections with coagulation cascades. Further sections are devoted to the current methods in the functional diagnostics of thrombocytes.