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Author : Frank Fenner,Adrian J. Gibbs
Publisher : S. Karger AG (Switzerland)
Page : 360 pages
File Size : 46,6 Mb
Release : 1988
Category : Medical
ISBN : MINN:31951D00005672H
Author : Neeraja Sankaran
Publisher : University of Pittsburgh Press
Page : 394 pages
File Size : 50,9 Mb
Release : 2021-03-30
Category : Science
ISBN : 9780822987710
In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell’s genetic material indefinitely, or until induced by UV radiation. But until Lwoff’s discovery of the mechanism of lysogeny, microbiologist Félix d’Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices.
Author : C.L. Mandahar
Publisher : CRC Press
Page : 374 pages
File Size : 48,6 Mb
Release : 2018-01-18
Category : Science
ISBN : 9781351084246
This book deals with the structure and replication of plant viruses, viroids, satellites of plant viruses, and spiroplasmas and neatly sums up the state of our knowledge about these aspects of these pathogens.Published information about single-stranded positive-sense RNA plant viruses is far greater than for any other group of plant pathogens.The book caters to the needs of students as well as researchers and is illustrated with micrographs, figures of postulated models, and genetic maps
Author : M.H.V. Van Regenmortel,Heinz Fraenkel-Conrat
Publisher : Springer Science & Business Media
Page : 428 pages
File Size : 42,9 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781468470260
This volume of the series The Plant Viruses is devoted to viruses with rod-shaped particles belonging to the following four groups: the toba moviruses (named after tobacco mosaic virus), the tobraviruses (after to bacco rattle), the hordeiviruses (after the latin hordeum in honor of the type member barley stripe mosaic virus), and the not yet officially rec ognized furoviruses (fungus-transmitted rod-shaped viruses, Shirako and Brakke, 1984). At present these clusters of plant viruses are called groups instead of genera or families as is customary in other areas of virology. This pe culiarity of plant viral taxonomy (Matthews, 1982) is due to the fact that the current Plant Virus Subcommittee of the International Committee of Taxonomy of Viruses is deeply split on what to call the categories or ranks used in virus classification. Some plant virologists believe that the species concept cannot be applied to viruses because this concept, according to them, necessarily involves sexual reproduction and genetic isolation (Milne, 1984; Murant, 1985). This belief no doubt stems from the fact that these authors restrict the use of the term species to biological species. According to them, a collection of similar viral isolates and strains does constitute an individ ual virus, i. e. , it is a taxonomy entity separate from other individual viruses.
Author : Anonim
Publisher : Academic Press
Page : 371 pages
File Size : 45,7 Mb
Release : 1998-11-03
Category : Medical
ISBN : 9780080583419
Advances in Virus Research
Author : Robert G. Francki R.I.B; Milne
Publisher : CRC Press
Page : 300 pages
File Size : 45,9 Mb
Release : 2018-01-18
Category : Science
ISBN : 9781351086844
This book assembles a comprehensive collection of plant virus electron micrographs of good quality, offers a consistent treatment, and backs the visual data with a consistent and comprehensive text. Although this book is primarily about the structure of virus particles and infected cells, the results of biochemical experiments are referred too when relevant, so that the virus particles described appear as part of a replicating complex. Similarly, infected cells are portrayed as active rather than static structures.
Author : R. E. F. Matthews
Publisher : Academic Press
Page : 916 pages
File Size : 42,9 Mb
Release : 2013-10-22
Category : Technology & Engineering
ISBN : 9781483258669
Plant Virology, Second Edition, was written to cover the substantial developments in many areas of plant virology since the first edition was published. Advances have been made in all branches of the subject, but these have been most far reaching with respect to the structure of viruses and of their components, and in the understanding of how viral genomes are organized and how viruses replicate in cells. Significant developments have also occurred in the understanding of how viruses are transmitted by invertebrates and in the application of control measures for specific diseases. The taxonomy of viruses has advanced significantly, and there are now 25 internationally approved families and groups of plant viruses. All these developments have required that most sections be entirely rewritten. This book is intended primarily for graduate students in plant pathology, plant virology, general virology, and microbiology, and for teachers and research workers in these fields. It should also prove useful to some people in related disciplines—molecular biologists, biochemists, plant physiologists, and entomologists.
Author : Steven Specter,Mauro Bendinelli,Herman Friedman
Publisher : Springer Science & Business Media
Page : 360 pages
File Size : 55,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468458862
There has been a tremendous increase in interest in the neuropathogenicity of viruses during the past decade as we have come to recognize that the human immunodeficiency virus, which causes the acquired immunodeficiency syndrome (AIDS), can infect glial cells and cause neurological disease. Yet this increase has not been limited to AIDS but has extended to viruses that infect either or both the central and peripheral nervous systems. The changes examined here include both neurological and psychological diseases or syndromes. Moreover, the chapters in this volume review the interaction of the host immune system with the viruses examined and how such interactions may increase or decrease the neuropatho genicity of the viruses. Questions regarding viral neuropathogenesis include: (I) What is the mode of transmission of virus to the nervous system? (2) What types of cells are infected, and do they contain receptors for the virus? (3) What is the extent of damage that results from viral infection? (4) What are the immunologic mecha nisms by which damage is mediated or limited? Many of these questions remain unanswered, but this volume delves into efforts to provide some answers.
Author : M.B.A. Oldstone
Publisher : Springer Science & Business Media
Page : 277 pages
File Size : 50,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642560552
Viruses are studied either because they cause significant human, animal or plant disease or because they are useful materials for probing basic phenomena in biology, chemistry, genetics and/or molecular biology. Arenaviruses are unusually interesting in that they occupy both categories. Arenaviruses cause several human diseases known primarily as the hemorrhagic fevers occurring in South and Latin America (Bolivia: Machupo, Argentine, Junin virus, and Brazil: Sabia virus) and in Africa (Lassa fever virus). Because such viruses produce profound disabilities and often kill the persons they infect, they are a source of health concern and economic hardship in the countries where they are prevalent. Further, they provide new problems for healthcare persons owing to the narrowing of the world as visitors from many countries travel increasingly to and from endemic areas and may incubate the infectious agent taking it from an endemic area into an area where the virus is not expected. Such cases are now being re corded with increasing frequency. In addition to these hemor rhagic fever viruses, the arenavirus lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling and severe than those elicited by the other arenaviruses. Yet, LCMV is of greater concern to non arenavirologists and experimentalists using tissue culture or ani mals, etc. , because normal-appearing cultured cells or tissues from animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and may transmit that infection to laboratory workers.
Author : R.T. Johnson,G. Lyon
Publisher : Springer Science & Business Media
Page : 164 pages
File Size : 43,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400912434
Author : P E. Came,L. A. Caliguiri
Publisher : Springer Science & Business Media
Page : 580 pages
File Size : 40,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642684876
" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of action, toxicity, pharmacokinetics, and pharmacodynamics of new agents. The list of clinically effective antiviral agents is expanding and the number of potentially useful compounds is growing rapidly. This book is a combined theoretical text and practical manual which, it is hoped, will be of use to all who have an interest in virus diseases, particularly scientists, physicians and graduate students.
Author : John Sidney Oxford,Bo Öberg
Publisher : Elsevier
Page : 740 pages
File Size : 51,7 Mb
Release : 1985
Category : Medical
ISBN : 9780444805669
Author : S. Myint,David Taylor-Robinson
Publisher : Springer Science & Business Media
Page : 504 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401179300
This book is a festschrift to mark the career of ogy, immunology and clinical aspects of each Dr David Tyrrell, eminent virologist and group. There are also more general chapters physician. Almost all of the contributors have overviewing the clinical manifestations, treat been colleagues or students at some time ment and pathophysiology of respiratory during his career. Unlike most festschrifts, virus infections. In addition, chapters in however, the essays have been integrated to which psychological aspects and the ethical produce a comprehensive book that covers use of human volunteers are discussed will be the entire field of non-bacterial infections of of interest to all those involved with respira the human respiratory tract. This is a measure tory infectious agents. of the breadth of interest of the research We hope also that this book serves as a undertaken by David, spanning a period of fitting tribute to a man who is a true poly over 40 years. math: a physician, researcher, teacher, We hope that this book will be of interest mentor, linguist and ambassador for science, to microbiologists, virologists and in particu among other things. To those of us who have lar, to physicians. All the major virus groups contributed to this book, he is even more: a are covered, as well as chlamydial and friend.
Author : M.V. Nermut,A.C. Steven
Publisher : Elsevier
Page : 441 pages
File Size : 40,5 Mb
Release : 1987-10-01
Category : Science
ISBN : 0080877389
Animal Virus Structure provides a comprehensive, state-of-the-art summary of the structure, molecular composition, and principal antigenic and biological properties of each currently recognized family of animal viruses. Information deriving from electron microscopy, computer image processing and X-ray diffraction is integrated systematically with biochemical data into three-dimensional molecular models of viral architecture. A brief account of virus/cell interaction and pathogenicity completes each chapter.
Author : E. de Clercq,E.R. Kern
Publisher : Elsevier
Page : 162 pages
File Size : 47,8 Mb
Release : 2003-04-17
Category : Medical
ISBN : 0444513264
The atrocities of 11 September 2001 and the more recent casualties due to anthrax bioterrorism have dramatically emphasized the potential danger of biological warfare and bioterrorism. The editors of "Antiviral Research" have taken the initiative to edit a special issue of the Journal, focusing on Viral Bioterrorism and Biodefense. It is the first time in history that a special volume has been dedicated to this topic, which in view of the current circumstances is timely, appropriate and relevant. To what extent could viruses be "weaponized", i.e. turned into biological weapons, and used for biowarfare, which viruses would lend themselves for this purpose, how should we estimate the risk and the consequences, which diagnostic measures should be taken, and how should we react prophylactically, and, if needed, therapeutically?