Post Genomic Perspectives In Modeling And Control Of Breathing

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Post-Genomic Perspectives in Modeling and Control of Breathing

Jean Champagnat,Monique Denavit-Saubie,Gilles Fortin,Arthur S. Foutz,Muriel Thoby-Brisson
Post Genomic Perspectives in Modeling and Control of Breathing Book PDF

Author : Jean Champagnat,Monique Denavit-Saubie,Gilles Fortin,Arthur S. Foutz,Muriel Thoby-Brisson
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 54,7 Mb
Release : 2010-06-28
Category : Medical
ISBN : 9780387270234

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Post-Genomic Perspectives in Modeling and Control of Breathing by Jean Champagnat,Monique Denavit-Saubie,Gilles Fortin,Arthur S. Foutz,Muriel Thoby-Brisson Pdf

Post Genomic Perspectives in Modeling and Control of Breathing is comprised of the proceedings of the IXth Oxford Conference on Modeling and Control of Breathing, held September 13-16, 2003 in Paris, France. This publication is placed within the general framework of post-genomic neurobiology, pathology, and the precise example of the rhythmic respiratory neural assembly being used to understand how genetic networks have been selected and conserved in the vertebrate brain. Specific topics include: ion channels and synapses responsible for respiratory rhythmogenesis and plasticity; pre- and post-natal development of the respiratory rhythm; chemosensory transduction and chemo-afferent signalling. These valuable insights open new avenues as to why the genetic codes underlying a vital function such as breathing have been selected, conserved, or optimized during evolution – a major issue of post-genomic biology. This critical issue will be considered from both top-down and bottom-up integrative modeling standpoints, with a view to elucidating the functional genomics linking discrete molecules to the integrated system that regulates breathing.

Post-Genomic Perspectives in Modeling and Control of Breathing

Jean Champagnat,Monique Denavit-Saubie,Gilles Fortin,Arthur S. Foutz,Muriel Thoby-Brisson
Post Genomic Perspectives in Modeling and Control of Breathing Book PDF

Author : Jean Champagnat,Monique Denavit-Saubie,Gilles Fortin,Arthur S. Foutz,Muriel Thoby-Brisson
Publisher : Springer
Page : 0 pages
File Size : 54,5 Mb
Release : 2010-11-16
Category : Medical
ISBN : 0387560041

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Post-Genomic Perspectives in Modeling and Control of Breathing by Jean Champagnat,Monique Denavit-Saubie,Gilles Fortin,Arthur S. Foutz,Muriel Thoby-Brisson Pdf

Post Genomic Perspectives in Modeling and Control of Breathing is comprised of the proceedings of the IXth Oxford Conference on Modeling and Control of Breathing, held September 13-16, 2003 in Paris, France. This publication is placed within the general framework of post-genomic neurobiology, pathology, and the precise example of the rhythmic respiratory neural assembly being used to understand how genetic networks have been selected and conserved in the vertebrate brain. Specific topics include: ion channels and synapses responsible for respiratory rhythmogenesis and plasticity; pre- and post-natal development of the respiratory rhythm; chemosensory transduction and chemo-afferent signalling. These valuable insights open new avenues as to why the genetic codes underlying a vital function such as breathing have been selected, conserved, or optimized during evolution – a major issue of post-genomic biology. This critical issue will be considered from both top-down and bottom-up integrative modeling standpoints, with a view to elucidating the functional genomics linking discrete molecules to the integrated system that regulates breathing.

Integration in Respiratory Control

Marc Poulin,Richard J. A. Wilson
Integration in Respiratory Control Book PDF

Author : Marc Poulin,Richard J. A. Wilson
Publisher : Springer Science & Business Media
Page : 554 pages
File Size : 41,5 Mb
Release : 2007-12-10
Category : Medical
ISBN : 9780387736938

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Integration in Respiratory Control by Marc Poulin,Richard J. A. Wilson Pdf

This volume comprises the proceedings of the 10th Oxford Conference held at Lake Louise, Alberta, Canada, in September, 2006. It contains the most up-to-date research in cardio-respiratory control and its content spans the disciplines of respiratory physiology, neurobiology, modeling, and biomedical engineering. The volume will be of interest to clinicians working with patients with breathing disorders.

New Frontiers in Respiratory Control

Ikuo Homma,Hiroshi Onimaru,Yoshinosuke Fukuchi
New Frontiers in Respiratory Control Book PDF

Author : Ikuo Homma,Hiroshi Onimaru,Yoshinosuke Fukuchi
Publisher : Springer Science & Business Media
Page : 374 pages
File Size : 54,6 Mb
Release : 2010-03-10
Category : Medical
ISBN : 9781441956927

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New Frontiers in Respiratory Control by Ikuo Homma,Hiroshi Onimaru,Yoshinosuke Fukuchi Pdf

Breathing is performed by the rhythmic contraction of respiratory muscles. It ma- tains homeostasis of the organism by taking in the oxygen necessary to live and work and by controlling the level of CO within the organism. At first glance, breathing 2 seems simple; however, it is produced by a complex system in the brain with various afferents and efferents. The control of breathing is of the utmost importance in s- taining life, and although more than 150 years have passed since research on brea- ing control was first begun, many unsolved mysteries still remain. Breathing is like watching the tides at a beach that are created by the vast, complex open sea. The first Oxford Conference on Modeling and Control of Breathing was held 30 years ago in September of 1978 at the University Laboratory of Physiology in Oxford, England. During this first conference, the participants engaged in a hot d- cussion on the problem of whether breathing rhythm was produced by pacemaker cells or a neural network. This was before the discovery of the Bötinger complex in the medulla, and at the time, central chemoreceptive areas were still the focus of research. This conference was an especially unforgettable moment in the dawning of the new age of respiratory research. It has since been held every 3 years in various countries around the globe and is widely appreciated as the best respiratory meeting in the world.

The Central Nervous System Control of Respiration

Anonim
The Central Nervous System Control of Respiration Book PDF

Author : Anonim
Publisher : Elsevier
Page : 441 pages
File Size : 43,9 Mb
Release : 2014-04-17
Category : Science
ISBN : 9780444632760

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The Central Nervous System Control of Respiration by Anonim Pdf

Respiration is one of the most basic motor activities crucial for survival of the individual. It is under total control of the central nervous system, which adjusts respiratory depth and frequency depending on the circumstances the individual finds itself. For this reason this volume not only reviews the basic control systems of respiration, located in the caudal brainstem, but also the higher brain regions, that change depth and frequency of respiration. Scientific knowledge of these systems is crucial for understanding the problems in the many patients suffering from respiratory failure. This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields

Breathing, Emotion and Evolution

Anonim
Breathing Emotion and Evolution Book PDF

Author : Anonim
Publisher : Elsevier
Page : 422 pages
File Size : 41,7 Mb
Release : 2014-09-04
Category : Science
ISBN : 9780444634955

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Breathing, Emotion and Evolution by Anonim Pdf

Respiration is one of the most basic motor activities crucial for survival of the individual. It is under total control of the central nervous system, which adjusts respiratory depth and frequency depending on the circumstances the individual finds itself. For this reason this volume not only reviews the basic control systems of respiration, located in the caudal brainstem, but also the higher brain regions, that change depth and frequency of respiration. Scientific knowledge of these systems is crucial for understanding the problems in the many patients suffering from respiratory failure. This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.

Respiratory Neurobiology

Anonim
Respiratory Neurobiology Book PDF

Author : Anonim
Publisher : Elsevier
Page : 462 pages
File Size : 52,9 Mb
Release : 2022-08-12
Category : Medical
ISBN : 9780323915359

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Respiratory Neurobiology by Anonim Pdf

Respiratory Neurobiology: Physiology and Clinical Disorders, Part One, Volume 188 is one of two volumes on the neurology of breathing. This volume focuses on the neurophysiology of breathing, while the second volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases. Explores the assessment and treatment of neural disorders of breathing Identifies neural complications of respiratory diseases Includes SIDS, stroke, Parkinson's, dementia, epilepsy, muscular dystrophy, and more

Physiological Responses to Intermittent Hypoxia in Humans

Jon C. Kolb
Physiological Responses to Intermittent Hypoxia in Humans Book PDF

Author : Jon C. Kolb
Publisher : Universal-Publishers
Page : 196 pages
File Size : 41,8 Mb
Release : 2004
Category : Medical
ISBN : 9781581122411

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Physiological Responses to Intermittent Hypoxia in Humans by Jon C. Kolb Pdf

Recently, endurance athletes and high altitude climbers have gained access to commercially available, portable normobaric hypoxic chambers. Intermittent exposures to hypoxia in these chambers may elicit adaptations similar to those observed during acclimatization to altitude. Manufactures of these systems purport that intermittent exposures may elicit adaptations similar to those observed in response to the hypoxia of high altitude, however there have been no reports in the scientific literature that ventilatory acclimatization or alterations in cerebrovascular dynamics occur following repeated episodes in the portable chambers. The main conclusions are that an intermittent normobaric hypoxic intervention, consisting of five consecutive overnight exposures to a simulated altitude of 4300m, elicits perturbations in the acute cerebrovascular and ventilatory responses to both hypoxia and hypercapnia, which are similar to changes following chronic altitude exposure. Individual variability to intermittent hypoxia may have an impact on the rate at which the process of acclimatization proceeds. The extent of physiological and symptomatic responses to intermittent hypoxia are likely to be associated with the severity of hypoxia as well as the length and number of recurrent episodes of hypoxia.

Respiratory Control

F.S. Grodins,G.D. Swanson,Richard L. Hughson
Respiratory Control Book PDF

Author : F.S. Grodins,G.D. Swanson,Richard L. Hughson
Publisher : Springer
Page : 488 pages
File Size : 45,8 Mb
Release : 1989
Category : Science
ISBN : UOM:39015018484066

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Respiratory Control by F.S. Grodins,G.D. Swanson,Richard L. Hughson Pdf

The fourth Oxford Conference entitled "Control of Breathing: A Model ing Perspective" was held in September of 1988 at Grand Lake, Colorado. Grand Lake, also called Spirit Lake, was chosen for the fourth meet i ng so as to continue the meditative atmosphere of the previ ous meetings and to put the conference on a new higher plane (8,500 feet). The weather, as promised, exhibited its random-like rain showers. The snow report became essential for traveling the 12,000 foot passes to and from Grand Lake. Even the servi ces such as telephone and elect ri city proved to be uncertain. In all, the overall atmosphere of Spirit Lake contributed to an uninhibited free-style of presentation and interaction. All of us who attend the Oxford Conferences share a common interest in exploring respiratory control and the regulation of breathing. Modeling has become an adjunct to our exploration process. For us, models are tools that extend our ability to conceptualize just as instruments are tools that extend our ability to measure. And so these meetings attract physicians, physiologists, mathematicians and engineers who are modelers and modelers who are engineers, mathematicians, physiologists and physicians. Four of these physician-modelers have now passed away. They have been very important mentors for many of us. J. W. Bellville was my Ph.D. dissertation advisor at Stanford who introduced me to the intrigue of respiratory control. G. F. Filley was my colleague at the University of Colorado who enhanced my thinking about respiratory control. E. S.

Animal Biotechnology

Ashish S. Verma,Anchal Singh
Animal Biotechnology Book PDF

Author : Ashish S. Verma,Anchal Singh
Publisher : Academic Press
Page : 685 pages
File Size : 55,6 Mb
Release : 2013-11-04
Category : Science
ISBN : 9780123914347

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Animal Biotechnology by Ashish S. Verma,Anchal Singh Pdf

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering

Cell Volume and Signaling

Peter Lauf,Norma Adragna
Cell Volume and Signaling Book PDF

Author : Peter Lauf,Norma Adragna
Publisher : Springer Science & Business Media
Page : 441 pages
File Size : 55,5 Mb
Release : 2006-11-30
Category : Science
ISBN : 9780387237527

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Cell Volume and Signaling by Peter Lauf,Norma Adragna Pdf

In front of you is the finished product of your work, the text of your contributions to the 2003 Dayton International Symposium on Cell Volume and Signal Transduction. As we all recall, this symposium brought together the Doyens of Cellular and Molecular Physiology as well as aspiring young investigators and students in this field. It became a memorable event in an illustrious series of International Symposia on Cell Volume and Signaling. This series, started by Professors Vladimir Strbák, Florian Lang and Monte Greer in Smolenice, Slovakia in 1997 and continued by Professors Rolf Kinne, Florian Lang and Frank Wehner in Berlin in 2000, is projected for 2005 in Copenhagen to be hosted by our colleague, Professor Else Hoffmann and her team. We dearly miss Monte Greer to whom this symposium was dedicated and addressed so eloquently by Vladimir Strbák in his Dedication to Monte. Monte and I became friends in Smolenice and had begun to discuss the 2003 meeting only a few days before his tragic accident in 2002. There are others who were not with us, and we missed them, too. We would not have been able to succeed in this event without the unflagging support of our higher administration at Wright State University, the NIDDKD of the National Institute of Health, and the Fuji Medical System (see Acknowledgments).

Protecting Infants through Human Milk

Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler
Protecting Infants through Human Milk Book PDF

Author : Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler
Publisher : Springer Science & Business Media
Page : 506 pages
File Size : 46,5 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781475742428

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Protecting Infants through Human Milk by Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler Pdf

Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.

Pheochromocytoma, Paraganglioma and Neuroblastoma

Pasquale Cianci,Enrico Restini,Amit Agrawal
Pheochromocytoma Paraganglioma and Neuroblastoma Book PDF

Author : Pasquale Cianci,Enrico Restini,Amit Agrawal
Publisher : BoD – Books on Demand
Page : 132 pages
File Size : 50,9 Mb
Release : 2021-08-18
Category : Medical
ISBN : 9781839689475

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Pheochromocytoma, Paraganglioma and Neuroblastoma by Pasquale Cianci,Enrico Restini,Amit Agrawal Pdf

Pheochromocytoma, paraganglioma and neuroblastoma are the most common neural crest-derived tumors in adults and children, respectively. These neoplasms are associated with significant morbidity and mortality. Some international studies currently underway are researching and evaluating the presence of any similarities and differences between these tumors. Hopefully, future results will reveal several potential novel genes and pathways that might have major roles in the pathogenesis and progression of these neoplasms. This book discusses epidemiology, genetics, and treatment of these malignancies.

Biomaterials

Nesrin Hasirci,Vasif Hasirci
Biomaterials Book PDF

Author : Nesrin Hasirci,Vasif Hasirci
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 42,5 Mb
Release : 2010-02-23
Category : Medical
ISBN : 9780306485848

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Biomaterials by Nesrin Hasirci,Vasif Hasirci Pdf

Biomaterials: From Molecules to Engineered Tissue gives examples of the application areas of biomaterials involving molecules at one end of the spectrum and finished devices in the other. It covers molecular approaches as well as molecules functional in preparing and modifying biomaterials, medical devices and systems, tissue engineering and artificial organs. Chapters on biomedical informatics and ethics complement the design and production aspects with their contribution in informatics and ethical concerns of biomedical research. This is a reference book for the advanced graduate student eager to learn the biomaterials area and for all researchers working in medicine, pharmacy, engineering and basic sciences in universities, hospitals, and industry involved in biomaterials and biomedical device production.

Defects of Secretion in Cystic Fibrosis

Carsten Schultz
Defects of Secretion in Cystic Fibrosis Book PDF

Author : Carsten Schultz
Publisher : Springer Science & Business Media
Page : 185 pages
File Size : 53,7 Mb
Release : 2007-07-13
Category : Medical
ISBN : 9780387232508

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Defects of Secretion in Cystic Fibrosis by Carsten Schultz Pdf

Defects in Secretion of Cystic Fibrosis presents an overview on current research from leading experts in North America and Europe. This update on cystic fibrosis provides in depth original work as well as review material on many of the relevant physiological and molecular topics in the field. Subjects covered include the interplay of the various epithelial ion channels, the underlying intracellular signal transduction, mucus secretion, and novel approaches to develop drugs against cystic fibrosis. This book brings together physicians, physiologists, and other scientists involved in basic research, from molecular biology to drug design and introduces novel investigative and therapeutic aspects of secretion disorders relevant in cystic fibrosis and related diseases. This book will be of interest to Molecular biologists, physiologists, scientists working in pharmaceutical research and drug developement, physicians and researchers in Cystic fibrosis and related diseases.