Practical Organic Synthesis

Author : Reinhart Keese,Martin P. Brändle,Trevor P. Toube
Publisher : John Wiley & Sons
Page : 209 pages
File Size : 43,7 Mb
Release : 2006-06-16
Category : Science
ISBN : 9780470029664

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Practical Organic Synthesis by Reinhart Keese,Martin P. Brändle,Trevor P. Toube Pdf

Success in an experimental science such as chemistry depends on good laboratory practice, a knowledge of basic techniques, and the intelligent and careful handling of chemicals. Practical Organic Synthesis is a concise, useful guide to good laboratory practice in the organic chemistry lab with hints and tips on successful organic synthesis. Topics covered include: safety in the laboratory environmentally responsible handling of chemicals and solvents crystallisation distillation chromatographic methods extraction and work-up structure determination by spectroscopic methods searching the chemical literature laboratory notebooks writing a report hints on the synthesis of organic compounds disposal and destruction of dangerous materials drying and purifying solvents Practical Organic Synthesis is based on a successful course in basic organic chemistry laboratory practice which has run for several years at the ETH, Zurich and the University of Berne, and its course book Grundoperationen, now in its sixth edition. Condensing over 30 years of the authors’ organic laboratory teaching experience into one easy-to-read volume, Practical Organic Synthesis is an essential guide for those new to the organic chemistry laboratory, and a handy benchtop guide for practising organic chemists.

Author : John Leonard,Barry Lygo,Garry Procter
Publisher : CRC Press
Page : 328 pages
File Size : 46,9 Mb
Release : 1994-06-02
Category : Science
ISBN : 0748740716

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Advanced Practical Organic Chemistry, Second Edition by John Leonard,Barry Lygo,Garry Procter Pdf

The first edition of this book achieved considerable success due to its ease of use and practical approach, and to the clear writing style of the authors. The preparation of organic compounds is still central to many disciplines, from the most applied to the highly academic and, more tan ever is not limited to chemists. With an emphasis on the most up-to-date techniques commonly used in organic syntheses, this book draws on the extensive experience of the authors and their association with some of the world's mleading laboratories of synthetic organic chemistry. In this new edition, all the figures have been re-drawn to bring them up to the highest possible standard, and the text has been revised to bring it up to date. Written primarily for postgraduate, advanced undergraduate and industrial organic chemists, particularly those involved in pharmaceutical, agrochemical and other areas of fine chemical research, the book is also a source of reference for biochemists, biologists, genetic engineers, material scientists and polymer researchers.

Author : Stéphane Caron
Publisher : John Wiley & Sons
Page : 850 pages
File Size : 53,6 Mb
Release : 2020-02-05
Category : Science
ISBN : 9781119448853

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Practical Synthetic Organic Chemistry by Stéphane Caron Pdf

This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale

Author : Arthur I. Vogel
Publisher : Unknown
Page : 1371 pages
File Size : 52,5 Mb
Release : 1984
Category : Electronic
ISBN : OCLC:60966632

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Vogel's Textbook of Practical Organic Chemistry by Arthur I. Vogel Pdf

Author : S. A. Richards,J. C. Hollerton
Publisher : John Wiley & Sons
Page : 345 pages
File Size : 45,7 Mb
Release : 2010-12-07
Category : Science
ISBN : 9780470977224

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Essential Practical NMR for Organic Chemistry by S. A. Richards,J. C. Hollerton Pdf

This book describes the use of NMR spectroscopy for dealing with problems of small organic molecule structural elucidation. It features a significant amount of vital chemical shift and coupling information but more importantly, it presents sound principles for the selection of the techniques relevant to the solving of particular types of problem, whilst stressing the importance of extracting the maximum available information from the simple 1-D proton experiment and of using this to plan subsequent experiments. Proton NMR is covered in detail, with a description of the fundamentals of the technique, the instrumentation and the data that it provides before going on to discuss optimal solvent selection and sample preparation. This is followed by a detailed study of each of the important classes of protons, breaking the spectrum up into regions (exchangeables, aromatics, heterocyclics, alkenes etc.). This is followed by consideration of the phenomena that we know can leave chemists struggling; chiral centres, restricted rotation, anisotropy, accidental equivalence, non-first-order spectra etc. Having explained the potential pitfalls that await the unwary, the book then goes on to devote chapters to the chemical techniques and the most useful instrumental ones that can be employed to combat them. A discussion is then presented on carbon-13 NMR, detailing its pros and cons and showing how it can be used in conjunction with proton NMR via the pivotal 2-D techniques (HSQC and HMBC) to yield vital structural information. Some of the more specialist techniques available are then discussed, i.e. flow NMR, solvent suppression, Magic Angle Spinning, etc. Other important nuclei are then discussed and useful data supplied. This is followed by a discussion of the neglected use of NMR as a tool for quantification and new techniques for this explained. The book then considers the safety aspects of NMR spectroscopy, reviewing NMR software for spectral prediction and data handling and concludes with a set of worked Q&As.

Author : H.M. Colquhoun,J. Holton,D.J. Thompson,M.V. Twigg
Publisher : Springer Science & Business Media
Page : 459 pages
File Size : 46,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461326519

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New Pathways for Organic Synthesis by H.M. Colquhoun,J. Holton,D.J. Thompson,M.V. Twigg Pdf

The continually growing contribution of transition metal chemistry to synthetic organic chemistry is, of course, widely recognized. Equally well known is the difficulty in keeping up-to-date with the multifarious reactions and procedures that seem to be spawned at an ever-increasing rate. These can certainly be summarized on the basis of reviews under the headings of the individual transition metals. More useful to the bench organic chemist, however, would be the opposite type of concordance based on the structural type of the desired synthetic product. This is the approach taken in the present monograph, which presents for each structural entity a conspectus of the transition metal-mediated processes that can be employed in its production. The resulting comparative survey should be a great help in devising the optimum synthetic approach for a particular goal. It is presented from an essentially practical viewpoint, with detailed direc tions interspersed in the Houben-Weyl style. The wide scope of the volume should certainly encourage synthetic organic chemists to utilize fully the range and versatility of these transition metal-mediated processes. This will certainly be a well-thumbed reference book! R. A. RAPHAEL Cambridge University v Preface In recent years an enormous amount of work has been done on the catalysis of organic reactions by various transition metal species and on the organic reactivity of organo-transition-metal compounds.

Author : Carlos A. M. Afonso,Nuno R. Candeias,Dulce Pereira Simão,Alexandre F. Trindade,Jaime A. S. Coelho,Bin Tan,Robert Franzén
Publisher : Royal Society of Chemistry
Page : 976 pages
File Size : 51,9 Mb
Release : 2016-12-16
Category : Science
ISBN : 9781849739634

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Comprehensive Organic Chemistry Experiments for the Laboratory Classroom by Carlos A. M. Afonso,Nuno R. Candeias,Dulce Pereira Simão,Alexandre F. Trindade,Jaime A. S. Coelho,Bin Tan,Robert Franzén Pdf

This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.

Author : Nicolas Bogliotti,Roba Moumné
Publisher : John Wiley & Sons
Page : 350 pages
File Size : 47,8 Mb
Release : 2017-08-04
Category : Science
ISBN : 9783527698998

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Multi-Step Organic Synthesis by Nicolas Bogliotti,Roba Moumné Pdf

Combining theoretical knowledge of synthetic transformations, practical considerations, structural elucidation by interpretation of spectroscopic data as well as rationalization of structure-property relations, this textbook presents a series of 16 independent exercises, including detailed descriptions of experimental procedures, questions, and answers. The experimental descriptions are very helpful for guiding less experienced students towards a better understanding of practical aspects in synthetic organic chemistry, while the broad scope of the questions and answers is excellent for learning purposes. The exercises are based on published research articles, adapted for didactic purposes, and will thus inspire students by way of having to solve real-life problems in chemistry. A must-have for MSc and PhD students as well as postdocs in organic chemistry and related disciplines, and lecturers and organizers of lab courses in organic chemistry.

Author : Arthur I. Vogel
Publisher : Unknown
Page : 1188 pages
File Size : 40,9 Mb
Release : 1972
Category : Electronic
ISBN : OCLC:634184368

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A text-book of practical organic chemistry by Arthur I. Vogel Pdf

Author : Dmitry V. Liskin,Penny Chaloner
Publisher : CRC Press
Page : 81 pages
File Size : 53,5 Mb
Release : 2015-11-04
Category : Medical
ISBN : 9781498722537

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Advanced Organic Synthesis by Dmitry V. Liskin,Penny Chaloner Pdf

Laboratory experience equips students with techniques that are necessary for professional practice. Advanced Organic Synthesis: A Laboratory Manual focuses on a mechanistic background of key reactions in organic chemistry, gives insight into well-established trends, and introduces new developments in the field.The book features experiments performe

Author : Davor Margetic,Vjekoslav Štrukil
Publisher : Elsevier
Page : 386 pages
File Size : 54,5 Mb
Release : 2016-04-23
Category : Science
ISBN : 9780128025253

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Mechanochemical Organic Synthesis by Davor Margetic,Vjekoslav Štrukil Pdf

Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendly methodologies for the synthesis of organic molecules of interest. Amongst the green methodologies drawing attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency. The development of synthetic strategies that require less, or the minimal, amount of energy to carry out a specific reaction with optimum productivity is of vital importance for large-scale industrial production. Experimental procedures at room temperature are the mildest reaction conditions (essentially required for many temperature-sensitive organic substrates as a key step in multi-step sequence reactions) and are the core of mechanochemical organic synthesis. This green synthetic method is now emerging in a very progressive manner and until now, there is no book that reviews the recent developments in this area. Features cutting-edge research in the field of mechanochemical organic synthesis for more sustainable reactions Integrates advances in green chemistry research into industrial applications and process development Focuses on designing techniques in organic synthesis directed toward mild reaction conditions Includes global coverage of mechanochemical synthetic protocols for the generation of organic compounds

Author : C. Oliver Kappe,Doris Dallinger,Shaun S. Murphree
Publisher : John Wiley & Sons
Page : 310 pages
File Size : 53,5 Mb
Release : 2008-11-21
Category : Science
ISBN : 9783527623914

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Practical Microwave Synthesis for Organic Chemists by C. Oliver Kappe,Doris Dallinger,Shaun S. Murphree Pdf

With the novice user in mind, this beginner's guide explains thebasics behind microwave technology, evaluates available instrumentsand reaction modes, and provides practical hints for everyeventuality. Includes 27 detailed protocols for often-usedreactions. From the contents: 1 Microwave Synthesis - An Introduction 2 Microwave Theory 3 Equipment Review 4 Microwave Processing Techniques 5 Starting With Microwave Chemistry 6 Experimental Protocols 6.1 General Small-Scale Sealed-Vessel Microwave Processing 6.2 Reaction Optimization 6.3 Library Generation 6.4 Reaction Scale-Up 6.5 Special Processing Techniques

Author : Frederick George Mann,Bernard Charles Saunders
Publisher : Orient Blackswan
Page : 612 pages
File Size : 51,8 Mb
Release : 1975
Category : Analytical chemistry
ISBN : 8125013806

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Practical Organic Chemistry by Frederick George Mann,Bernard Charles Saunders Pdf

A Clear And Reliable Guide To Students Of Practical Organic Chemistry At The Undergraduate And Postgraduate Levels. This Edition S Special Emphasis Is On Semi Micro Methods And Modern Techniques And Reactions.

Author : Alfred Hassner,Irishi Namboothiri
Publisher : Elsevier
Page : 612 pages
File Size : 47,8 Mb
Release : 2012-01-05
Category : Science
ISBN : 9780080966304

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Organic Syntheses Based on Name Reactions by Alfred Hassner,Irishi Namboothiri Pdf

Rev. ed. of: Organic syntheses based on name reactions and unnamed reactions. 1st ed. 1994.

Author : Goutam Brahmachari
Publisher : Elsevier
Page : 386 pages
File Size : 45,5 Mb
Release : 2015-03-19
Category : Science
ISBN : 9780128011386

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Room Temperature Organic Synthesis by Goutam Brahmachari Pdf

Filling a gap in the scientific literature, Room Temperature Organic Synthesis is unique in its authoritative, thorough, and applied coverage of a wide variety of "green" organic synthetic methodologies. The book describes practical, feasible protocols for room temperature reactions to produce carbon-carbon and carbon-heteroatom bond formations including aliphatic, aromatic, alicyclic, heterocycles, and more. Consistently organized for easy access, each selected reaction is discussed in a very compact and structured manner including: reaction type, reaction condition, reaction strategy, catalyst, keywords, general reaction scheme, mechanism (in selected cases), representative entries, experimental procedure, characterization data of representative entries, and references. This book will be a valuable resource for synthetic organic, natural products, medicinal, and biochemists as well as those working in the pharmaceutical and agrochemical industry. Includes more than 300 protocols for a green approach to organic synthesis Provides specific detail about experimental conditions Increases efficiency in the laboratory by eliminating time-consuming literature searches