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Author : Mrs. S. R. Kale,Mr. R. R. Kale Dr. S. A. Hasan
Publisher : Nirali Prakashan
Page : 84 pages
File Size : 41,7 Mb
Release : 2008-07-07
Category : Electronic
ISBN : 8185790493
Author : V. Sharma
Publisher : CBS Publishers & Distributors Pvt Limited, India
Page : 81 pages
File Size : 50,5 Mb
Release : 2018-10-30
Category : Medical
ISBN : 8123914253
This practical notebook contains 17 experiments, is well illustrated with graphs, and gives experimental data to make the experiments more meaningful to students. Blank pages have been provided at the end of the manual to allow students to write additional experiments.
Author : Mrs. S. R. Kale
Publisher : Pragati Books Pvt. Ltd.
Page : 238 pages
File Size : 46,6 Mb
Release : 2008-08-07
Category : Pharmacology
ISBN : 8185790248
Author : David Woolley,Adam Woolley
Publisher : CRC Press
Page : 472 pages
File Size : 52,9 Mb
Release : 2008-09-22
Category : Medical
ISBN : 9781420043150
This practical, user-friendly, and informative text surveys basic principles of toxicology. It is an invaluable guide to evaluating toxicity and related data, approaching toxicity testing and interpretation, and understanding the concepts of hazard prediction and risk assessment and management. A Guide to Practical Toxicology: examines how to evaluate various groups of chemicals—pharmaceuticals, cosmetics, and agrochemicals provides insights on toxicity determination, normality and naturality, prediction, and regulation Two all-new chapters cover: safety pharmacology evaluation of different chemical classes
Author : David Woolley,Adam Woolley
Publisher : CRC Press
Page : 528 pages
File Size : 45,6 Mb
Release : 2017-03-16
Category : Medical
ISBN : 9781498709309
Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data. Revised and updated chapters on risk assessment guide the reader to setting the foundations necessary for submission to regulatory authorities. In addition, a new chapter in the book reviews the errors in toxicology, mistakes, misuse, mismanagement, and misunderstanding with a view to avoiding these in the future. New Chapters in the Third Edition: Toxicology in silico Errors in Toxicology Safety Assessment of Extractables and Leachables. This new edition follows a practical sequence from introducing the basics of toxicology (including the vital concept of normality in controls) to describing a test program and then interpreting the data and translating that to risk assessment that can be used in a number of real world situations where safety and secure risk assessment are essential. Although written primarily from the perspective of pharmaceutical development, the test designs and toxicological problems encountered in that field are entirely relevant to those with other classes of chemicals, the only difference being the regulatory context. Toxicology is an international discipline and the book has been written to take into account some of the differences in regulatory nuance between the main regions of the world. Completely revised and written in an easily accessible style, the text address several audiences—from students and post-graduates coming to the subject for the first time to established professionals who find themselves needing to learn about toxicology, toxicity testing, interpretation of the results, and risk assessment. It is intended primarily as a textbook, with case studies and information on where to go to ask questions, but can also be used as a practical reference book. It covers all the basics of toxicology and the main aspects of safety evaluation testing and risk assessment while reviewing critically the current state of the discipline. It also provides a foundation for those seeking registration or certification.
Author : Ali S. Faqi
Publisher : Elsevier
Page : 1074 pages
File Size : 48,9 Mb
Release : 2024-02-11
Category : Medical
ISBN : 9780323984621
A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology
Author : Shayne C. Gad,Carrol S. Weil
Publisher : CRC Press
Page : 400 pages
File Size : 55,8 Mb
Release : 1989-12-15
Category : Medical
ISBN : 0936923180
This book serves as a primary text for students of pharmacology, toxicology, and biology, and as a practical handbook to support the daily operations of the toxicology laboratory and researcher. This edition retains the structure of earlier editions, but has been extensively revised to provide both the student and the working toxicologist with the necessary tools for the rigorous and critical design of studies and analysis of experimental data.
Author : Brian C. Gilger
Publisher : Unknown
Page : 0 pages
File Size : 43,7 Mb
Release : 2014
Category : Anatomy
ISBN : 1627037454
"Covering ocular pharmacokinetics, pharmacodynamics, and toxicology, Ocular Pharmacology and Toxicology provides ophthalmologists, toxicologists, and pharmacologists with both an introduction to the proper methods for ocular pharmacology and toxicology as well as providing practical methodologies for conducting ocular studies. Expert authors have contributed detailed chapters on study design, analysis, and routes to regulatory approval for various types and routes of ophthalmic drugs. As a volume in the Methods in Pharmacology and Toxicology series, chapters feature the kind of in-depth specifics and implementation advice to ensure successful results. Practical and authoritative, Ocular Pharmacology and Toxicology serves as an ideal basis of training in the proper design and conduct of essential studies to accurately determine pharmacokinetics and ocular toxicity from the systemic, topical, periocular, or intraocular administration of drugs or compounds, from the use of ocular medical devices and from ocular surgical procedures."--Publisher's description.
Author : Bikash Mehdi,Ajay Prakash
Publisher : Jaypee Brothers,Medical Publishers Pvt. Limited
Page : 430 pages
File Size : 46,6 Mb
Release : 2016-10-26
Category : Medical
ISBN : 9386150727
Author : DR. K. N. JAYAVEERA
Publisher : Unknown
Page : 128 pages
File Size : 44,7 Mb
Release : 2014
Category : Electronic
ISBN : 8121942497
Author : Ali S. Faqi
Publisher : Academic Press
Page : 904 pages
File Size : 49,7 Mb
Release : 2012-11-02
Category : Business & Economics
ISBN : 9780123878151
A Comprehensive Guide to Toxicology in Preclinical Drug Development is designed for toxicologists who need a thorough understanding of the drug development process. This multi-contributed reference will provide a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics --
Author : G. D. Gupta
Publisher : Unknown
Page : 58 pages
File Size : 55,9 Mb
Release : 2020-02
Category : Medical
ISBN : 9386700158
Author : Alberto Lodola,Jeanne Stadler
Publisher : John Wiley & Sons
Page : 280 pages
File Size : 47,5 Mb
Release : 2011-03-31
Category : Medical
ISBN : 9780470922729
This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.
Author : Ethan B Russo
Publisher : Routledge
Page : 482 pages
File Size : 48,7 Mb
Release : 2013-09-05
Category : Health & Fitness
ISBN : 9781136614934
Study the latest research findings by international experts! This comprehensive volume presents state-of-the-art scientific research on the therapeutic uses of cannabis and its derivatives. All too often, discussions of the potential medical uses of this substance are distorted by political considerations that have no place in a medical debate. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential features fair, equitable discussion of this emerging and controversial medical topic by the world’s foremost researchers. Cannabis and Cannabinoids examines the benefits, drawbacks, and side effects of medical marijuana as a treatment for various conditions and diseases. This book discusses the scientific basis for marijuana’s use in cases of pain, nausea, anorexia, and cachexia. It also explores its possible benefits in glaucoma, ischemia, spastic disorders, and migraine. Cannabis and Cannabinoids examines all facets of the medical use of marijuana, including: botany history biochemistry pharmacology clinical use toxicology side effects Cannabis and Cannabinoids is a reference work that will become indispensable to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public. No other book available offers this comprehensive, even-handed look at a deeply divisive subject.
Author : D. Michael Salmon
Publisher : John Wiley & Sons
Page : 162 pages
File Size : 47,8 Mb
Release : 2013-12-19
Category : Medical
ISBN : 9781118696569
Practical Pharmacology for the Pharmaceutical Sciences is a lab survival guide for those studying Pharmacology, providing hands-on advice on developing pharmacology laboratory and data handling skills. Suitable for both undergraduates and postgraduates, it focuses on laboratory techniques rather than computer-simulated data. It also guides the reader through the process of communicating experimental results in a variety of formats, including posters, oral presentations and project reports. Split into three main areas, the following topics are covered in detail: Preparation for Experimental Pharmacology Legal aspects Fundamentals of Pharmacology Definitions, calculations and statistics Experiments in Pharmacology Microtitre-based techniques using isolated cells In vitro techniques using isolated tissues and organs Biochemical techniques using cell-free systems Communicating experimental results Data presentation How to write scientific reports Pharmacological literature Supported with numerous questions throughout the text, as well as step by step instructions for practical experiments, this book presents an approach to learning pharmacology through an appreciation of authentic experimental data.