Precision Medicine In Chronic Inflammation

Author : Geoffrey S. Ginsburg,Huntington F Willard,Christopher W. Woods,Ephraim L. Tsalik
Publisher : Academic Press
Page : 480 pages
File Size : 53,9 Mb
Release : 2019-08-15
Category : Science
ISBN : 9780128015582

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Genomic and Precision Medicine by Geoffrey S. Ginsburg,Huntington F Willard,Christopher W. Woods,Ephraim L. Tsalik Pdf

Genomic and Precision Medicine: Infectious and Inflammatory Disease, Third Edition, provides current clinical solutions on the application of genome discovery on a broad spectrum of disease categories in IMD - including asthma, obesity and multiple sclerosis. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies, along with information on a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Offers comprehensive coverage of infectious and inflammatory disease genomics Provides succinct commentary and key learning points to assist providers with the implementation of genomic and personalized medicine Presents an up-to-date overview on major opportunities for genomic and personalized medicine Includes case studies that highlight the practical use of genomics in the management of patients

Author : Luca Antonioli,Moshe Biton,Ilaria Puxeddu
Publisher : Frontiers Media SA
Page : 175 pages
File Size : 55,7 Mb
Release : 2022-03-09
Category : Science
ISBN : 9782889746293

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Precision Medicine and Immuno-Mediated Inflammatory Diseases: Latest Progress and Next Challenges by Luca Antonioli,Moshe Biton,Ilaria Puxeddu Pdf

Author : Ioana Agache,Peter Hellings
Publisher : Academic Press
Page : 228 pages
File Size : 43,8 Mb
Release : 2018-09-19
Category : Medical
ISBN : 9780128134726

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Implementing Precision Medicine in Best Practices of Chronic Airway Diseases by Ioana Agache,Peter Hellings Pdf

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases provides a comprehensive overview of the application of precision medicine in airway diseases with a goal of promoting optimal control of disease, higher patient satisfaction and disease prevention. As medical research continues to fund this area, the book highlights the need for implementation of the principles of precision medicine into the bedside management of chronic airway diseases. It is clear that chronic airway diseases are heterogeneous and that a personalized approach is warranted whereby treatment is tailored to the level of the individual patient. Written for basic researchers, medical doctors and other healthcare practitioners this book provides guidance on the implementation of the principles of precision medicine into further research and daily clinical practice. Bridges the gap between precision medicine research and the implementation of the principles into daily clinical practice Includes contributions from key opinion leaders in the field of airway disease giving a worldwide perspective Discusses precision medicine in terms of personalized and stratified medicine, biomarkers, prediction of success, participation of the patient and prevention of disease

Author : João Eurico Fonseca,Frances Claire Humby,Carl Kieran Orr
Publisher : Frontiers Media SA
Page : 129 pages
File Size : 48,9 Mb
Release : 2022-01-13
Category : Medical
ISBN : 9782889740598

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Synovial Tissue: Turning the Page to Precision Medicine in Arthritis? by João Eurico Fonseca,Frances Claire Humby,Carl Kieran Orr Pdf

Author : Xu-jie Zhou,Lam Cheung Tsoi,Amanda S. MacLeod
Publisher : Frontiers Media SA
Page : 227 pages
File Size : 40,6 Mb
Release : 2022-08-16
Category : Medical
ISBN : 9782889765836

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Towards Precision Medicine for Immune-Mediated Disorders: Advances in Using Big Data and Artificial Intelligence to Understand Heterogeneity in Inflammatory Responses by Xu-jie Zhou,Lam Cheung Tsoi,Amanda S. MacLeod Pdf

Topic Editor Dr. MacLeod is employed by Janssen. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Author : Anonim
Publisher : Frontiers Media SA
Page : 159 pages
File Size : 54,7 Mb
Release : 2021-11-09
Category : Medical
ISBN : 9782889716159

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Precision Medicine in Chronic Inflammation by Anonim Pdf

Author : Josep Bassaganya-Riera
Publisher : Springer
Page : 82 pages
File Size : 40,6 Mb
Release : 2018-04-25
Category : Medical
ISBN : 9783319732381

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Accelerated Path to Cures by Josep Bassaganya-Riera Pdf

Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical trials and post-approval monitoring, as alternative models of drug development. As a case of successful integration of computational modeling and drug development, we discuss the development of oral small molecule therapeutics for inflammatory bowel disease, from the application of docking studies to screening new chemical entities to the development of next-generation in silico human clinical trials from large-scale clinical data. Additionally, this book illustrates how modeling techniques, machine learning, and informatics can be utilized effectively at each stage of drug development to advance the progress towards predictive, preventive, personalized, precision medicine, and thus provide a successful framework for Path to Cures.

Author : Michael Mahler
Publisher : Academic Press
Page : 300 pages
File Size : 46,7 Mb
Release : 2021-03-12
Category : Science
ISBN : 9780323854320

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Precision Medicine and Artificial Intelligence by Michael Mahler Pdf

Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

Author : Geoffrey S. Ginsburg,Huntington F Willard,John Strickler,Matthew Stuart McKinney
Publisher : Academic Press
Page : 379 pages
File Size : 42,8 Mb
Release : 2022-04-09
Category : Science
ISBN : 9780128006535

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Genomic and Precision Medicine by Geoffrey S. Ginsburg,Huntington F Willard,John Strickler,Matthew Stuart McKinney Pdf

Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice Covers case studies that highlight the practical use of genomics in the management of patients

Author : Geoffrey S. Ginsburg,Huntington F Willard,Sean P. David
Publisher : Academic Press
Page : 370 pages
File Size : 54,9 Mb
Release : 2017-03-30
Category : Science
ISBN : 9780128006542

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Genomic and Precision Medicine by Geoffrey S. Ginsburg,Huntington F Willard,Sean P. David Pdf

Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care. One of the major areas where genomic and personalized medicine is most active is the realm of the primary care practitioner. Risk, family history, personal genomics and pharmacogenomics are becoming increasingly important to the PCP and their patients, and this book discusses the implications as they relate to primary care practitioners. Presents a comprehensive volume for primary care providers Provides succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine Includes a current overview on major opportunities for genomic and personalized medicine in practice Highlights case studies that illustrate the practical use of genomics in the management in patients

Author : Richard H. Carmona,Mark Liponis
Publisher : Oxford University Press
Page : 585 pages
File Size : 40,6 Mb
Release : 2017-12-12
Category : Medical
ISBN : 9780190241254

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Integrative Preventive Medicine by Richard H. Carmona,Mark Liponis Pdf

For most clinicians, the science and evidence for many integrative therapies is largely unknown or considered suspect. Most physicians don't have time to learn integrative approaches and aren't sure what to recommend or which approaches have merit or improved outcomes. Here, clinicians have easy access to the best practices in integrative medicine and expectations for outcomes

Author : Adam Bohr,Kaveh Memarzadeh
Publisher : Academic Press
Page : 385 pages
File Size : 46,9 Mb
Release : 2020-06-21
Category : Computers
ISBN : 9780128184394

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Artificial Intelligence in Healthcare by Adam Bohr,Kaveh Memarzadeh Pdf

Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Author : Ganji Purnachandra Nagaraju,Sujatha Peela
Publisher : Academic Press
Page : 388 pages
File Size : 55,8 Mb
Release : 2022-02-16
Category : Psychology
ISBN : 9780323993647

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Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 1 by Ganji Purnachandra Nagaraju,Sujatha Peela Pdf

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume One: Biology and Pathophysiology provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This volume discusses topics such as tumor microenvironment in hepatocellular carcinoma, endoplasmic reticulum stress and unfolded protein response, effects of cirrhosis and hepatitis on the prognosis of HCC, mitochondrial metabolism, next generation sequencing, and telomerase. In addition, it discusses exosomes role in HCC progression, metastasis and chemokines. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer for their research work or clinical setting. Provides an updated literature review and detailed understanding of liver cancer tumor biology Discusses abnormal changes in the liver caused, resulting from, or associated with hepatocellular carcinoma from a holistic view Presents the content with fully colored images and summarizing tables for easy understanding of complex topics

Author : Peter L. M. Kerkhof,Virginia M. Miller
Publisher : Springer
Page : 725 pages
File Size : 49,9 Mb
Release : 2018-07-26
Category : Medical
ISBN : 9783319779324

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Sex-Specific Analysis of Cardiovascular Function by Peter L. M. Kerkhof,Virginia M. Miller Pdf

This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.

Author : Ganji Purnachandra Nagaraju,Sarfraz Ahmad
Publisher : Academic Press
Page : 469 pages
File Size : 51,6 Mb
Release : 2022-04-15
Category : Computers
ISBN : 9780323992848

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Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 3 by Ganji Purnachandra Nagaraju,Sarfraz Ahmad Pdf

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma: Translational and Clinical Outcomes, Volume Three provides comprehensive information about ongoing research and clinical data on liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This updated volume discusses topics such as clinical and safety assessment of HCC patients, liver transplantation as a therapeutic option, immunotherapy interventions, and image-based surveillance. In addition, it discusses immunohistology of HCC-enabled precision medicine and artificial intelligence for hepatocellular carcinomas. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting. Provides best practices for the management of hepatocellular carcinoma in the clinical setting Discusses emerging treatment approaches based on artificial intelligence and precision medicine tools and techniques Brings updated information on international clinical trials for the treatment of HCC