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Author : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations
Publisher : Unknown
Page : 724 pages
File Size : 52,7 Mb
Release : 2004
Category : Medical
ISBN : UVA:X005105317
Author : United States. Congress. House. Committee on Energy and Commerce
Publisher : Unknown
Page : 308 pages
File Size : 42,5 Mb
Release : 2005
Category : Energy policy
ISBN : STANFORD:36105050382428
Author : Anonim
Publisher : Unknown
Page : 600 pages
File Size : 46,7 Mb
Release : 2005
Category : Government publications
ISBN : OSU:32437122349281
Author : Alison Bass
Publisher : Algonquin Books
Page : 273 pages
File Size : 55,6 Mb
Release : 2008-06-17
Category : Medical
ISBN : 9781565126435
As the mental health reporter for the Boston Globe, Alison Bass's front-page reporting on conflicts of interest in medical research stunned readers, and her series on sexual misconduct among psychiatrists earned a Pulitzer Prize nomination. Now she turns her investigative skills to a controversial case that exposed the increased suicide rates among adolescents taking antidepressants such as Paxil, Prozac, and Zoloft. Side Effects tells the tale of a gutsy assistant attorney general who, along with an unlikely whistle-blower at an Ivy League university, uncovered evidence of deception behind one of the most successful drug campaigns in history. Paxil was the world's bestselling antidepressant in 2002. Pediatric prescriptions soared, even though there was no proof that the drug performed any better than sugar pills in treating children and adolescents, and the real risks the drugs posed were withheld from the public. The New York State Attorney General's office brought an unprecedented lawsuit against giant manufacturer GlaxoSmithKline, the maker of Paxil, for consumer fraud. The successful suit launched a tidal wave of protest that changed the way drugs are tested, sold, and marketed in this country. With meticulous research, Alison Bass shows us the underbelly of the pharmaceutical industry. She lays bare the unhealthy ties between the medical establishment, big pharma, and the FDA—relationships that place vulnerable children and adults at risk every day.
Author : Scott N. Compton,Marianne A. Villabo,Hanne Kristensen
Publisher : Academic Press
Page : 570 pages
File Size : 40,8 Mb
Release : 2019-03-28
Category : Psychology
ISBN : 9780128130056
Pediatric Anxiety Disorders provides a critical, updated and comprehensive overview of anxiety disorders in children and adolescents based on the current state of empirical research. The book provides specific clinical recommendations which integrate new knowledge from neuroscience and innovative delivery formats for interventions. This is the first reference to examine anxiety diagnoses in accordance with the latest edition of the DSM-5, including childhood onset disorders, such as Separation Anxiety Disorder, Selective Mutism, Specific Phobia, Social Anxiety Disorder, Panic Disorder, Agoraphobia and Generalized Anxiety Disorder. The book assists clinicians in critically appraising the certainty of the evidence-base and the strength of clinical recommendations. Uses the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, the DSM-5 Includes the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach in assessing guideline development Focuses on advances in etiology, assessment and treatment Presents new advances in our understanding of the brain behind fear and anxiety Uses a stepped care approach to treatment
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Clinical Research Involving Children
Publisher : National Academies Press
Page : 445 pages
File Size : 50,9 Mb
Release : 2004-07-09
Category : Medical
ISBN : 9780309133388
In recent decades, advances in biomedical research have helped save or lengthen the lives of children around the world. With improved therapies, child and adolescent mortality rates have decreased significantly in the last half century. Despite these advances, pediatricians and others argue that children have not shared equally with adults in biomedical advances. Even though we want children to benefit from the dramatic and accelerating rate of progress in medical care that has been fueled by scientific research, we do not want to place children at risk of being harmed by participating in clinical studies. Ethical Conduct of Clinical Research Involving Children considers the necessities and challenges of this type of research and reviews the ethical and legal standards for conducting it. It also considers problems with the interpretation and application of these standards and conduct, concluding that while children should not be excluded from potentially beneficial clinical studies, some research that is ethically permissible for adults is not acceptable for children, who usually do not have the legal capacity or maturity to make informed decisions about research participation. The book looks at the need for appropriate pediatric expertise at all stages of the design, review, and conduct of a research project to effectively implement policies to protect children. It argues persuasively that a robust system for protecting human research participants in general is a necessary foundation for protecting child research participants in particular.
Author : Graziano Pinna
Publisher : Unknown
Page : 412 pages
File Size : 42,8 Mb
Release : 2015-04-01
Category : Electronic
ISBN : 1634820762
Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure.
Author : Anonim
Publisher : ScholarlyEditions
Page : 440 pages
File Size : 50,6 Mb
Release : 2013-01-10
Category : Medical
ISBN : 9781481645904
Issues in Discovery, Experimental, and Laboratory Medicine: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Medical Research. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Medical Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Alexander Glassman,Mario M. Maj,Norman Sartorius
Publisher : John Wiley & Sons
Page : 110 pages
File Size : 43,6 Mb
Release : 2011-06-20
Category : Medical
ISBN : 9781119957621
Recently, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. Patients with psychiatric problems, particularly depression, may be more susceptible to cardiovascular disorders. Depression and Heart Disease synthesizes current evidence, including some previously unpublished data, in a concise, easy-to-read format. The authors succinctly describe the epidemiology, pathogenesis (including cytokines and genetics), and risk factors of the comorbidity between depression and heart disease. The book also reviews the best pharmacological and psychotherapeutic approaches for people with this comorbidity.
Author : Bob Fiddaman
Publisher : Chipmunkapublishing ltd
Page : 332 pages
File Size : 46,7 Mb
Release : 2024-06-30
Category : Electronic
ISBN : 9781849911207
Author : George MacLean
Publisher : Unknown
Page : 152 pages
File Size : 51,8 Mb
Release : 1990
Category : Adolescent psychotherapy
ISBN : UOM:39015018314032
Author : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations
Publisher : Unknown
Page : 646 pages
File Size : 52,7 Mb
Release : 2005
Category : Antidepressants
ISBN : UCSD:31822030310940
Author : Peter Fonagy,David Cottrell,Jeannette Phillips,Dickon Bevington,Danya Glaser,Elizabeth Allison
Publisher : Guilford Publications
Page : 656 pages
File Size : 42,5 Mb
Release : 2015-11-12
Category : Psychology
ISBN : 9781462525928
The standard reference in the field, this acclaimed work synthesizes findings from hundreds of carefully selected studies of mental health treatments for children and adolescents. Chapters on frequently encountered clinical problems systematically review the available data, identify gaps in what is known, and spell out recommendations for evidence-based practice. The authors draw on extensive clinical experience as well as research expertise. Showcasing the most effective psychosocial and pharmacological interventions for young patients, they also address challenges in translating research into real-world clinical practice. New to This Edition *Incorporates over a decade of research advances and evolving models of evidence-based care. *New chapter topic: child maltreatment. *Separate chapters on self-injurious behavior, eating disorders, and substance use disorders (previously covered in a single chapter on self-harming disorders). *Expanded chapters on depression, anxiety, and conduct disorder. *Includes reviews of the burgeoning range of manualized psychosocial "treatment packages" for children.
Author : Kevin Dew,Anne Scott,Allison Kirkman
Publisher : Springer
Page : 247 pages
File Size : 44,9 Mb
Release : 2016-05-09
Category : Social Science
ISBN : 9783319315089
This book comprehensively explores social, political and cultural dimensions of health in contemporary society. It addresses many issues and pertinent questions, including the following: Are we over diagnosed and over medicated? How can patients participate in their own care? Do pharmaceutical companies coerce us into medication regimes? What drives inequalities in health outcomes? What is the experience of health care for indigenous communities? Why do different countries have such different health care systems? How do we respond to life-changing conditions? Can we achieve a ‘good death’? How do new genetics shape our identities? Is public health a force of liberation or disempowerment? The book incorporates the range of levels of influence on health, covering individual patient experiences, the health professions, multinational corporations, the state, global organisations as well as examining trends in social organisation, cultural expression and technological developments. It volume provides an accessible, yet in-depth, overview and discussion of the sociology of health. The chapters include an illustrative case study and further readings relating to the topic.
Author : Rebecca Weintraub Brendel,Michelle Hume
Publisher : Elsevier Health Sciences
Page : 161 pages
File Size : 41,6 Mb
Release : 2021-11-13
Category : Medical
ISBN : 9780323835695
This issue of Psychiatric Clinics, guest edited by Drs. Rebecca Brendel and Michelle will discuss a number of important topics surrounding Psychiatric Ethics and impact on clinical practice. This issue is one of four each year selected by our series consulting editor, Dr. Harsh Trivedi of Sheppard Pratt Health System. Topics in this issue include: Ethics in Psychiatric Research, Ethical Aspects of Trauma Informed Care, Ethical Challenges in Addiction Psychiatry, Ethics in Child and Adolescent Psychiatry, Forensic Psychiatric Ethics, Geriatric Psychiatry Ethics, Ethics of emerging technologies, Ethical considerations in Psychiatric Genetics, Organizational Ethics, Suicide and the end of life, Psychiatry in public spaces, Autonomy and Multiculturalism, and Justice and Parity in Mental Health Treatment, among others.
