Quantitative Imaging

Author : Nicole Seiberlich,Vikas Gulani,Adrienne Campbell-Washburn,Steven Sourbron,Mariya Ivanova Doneva,Fernando Calamante,Houchun Harry Hu
Publisher : Academic Press
Page : 1094 pages
File Size : 44,9 Mb
Release : 2020-11-18
Category : Computers
ISBN : 9780128170588

Get Book

Quantitative Magnetic Resonance Imaging by Nicole Seiberlich,Vikas Gulani,Adrienne Campbell-Washburn,Steven Sourbron,Mariya Ivanova Doneva,Fernando Calamante,Houchun Harry Hu Pdf

Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Author : Habib Zaidi
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 50,9 Mb
Release : 2006-07-11
Category : Science
ISBN : 9780387254449

Get Book

Quantitative Analysis in Nuclear Medicine Imaging by Habib Zaidi Pdf

This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.

Author : Anonim
Publisher : Academic Press
Page : 588 pages
File Size : 42,9 Mb
Release : 2014-06-25
Category : Science
ISBN : 9780124202016

Get Book

Quantitative Imaging in Cell Biology by Anonim Pdf

This new volume, number 123, of Methods in Cell Biology looks at methods for quantitative imaging in cell biology. It covers both theoretical and practical aspects of using optical fluorescence microscopy and image analysis techniques for quantitative applications. The introductory chapters cover fundamental concepts and techniques important for obtaining accurate and precise quantitative data from imaging systems. These chapters address how choice of microscope, fluorophores, and digital detector impact the quality of quantitative data, and include step-by-step protocols for capturing and analyzing quantitative images. Common quantitative applications, including co-localization, ratiometric imaging, and counting molecules, are covered in detail. Practical chapters cover topics critical to getting the most out of your imaging system, from microscope maintenance to creating standardized samples for measuring resolution. Later chapters cover recent advances in quantitative imaging techniques, including super-resolution and light sheet microscopy. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

Author : Julien Cohen-Adad,Claudia Wheeler-Kingshott
Publisher : Academic Press
Page : 330 pages
File Size : 41,7 Mb
Release : 2014-01-16
Category : Medical
ISBN : 9780123972828

Get Book

Quantitative MRI of the Spinal Cord by Julien Cohen-Adad,Claudia Wheeler-Kingshott Pdf

Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. Chapters authored by international experts in the field of MRI of the spinal cord Contains “cooking recipes —examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice Ideal for clinical settings

Author : J.M. Blackledge
Publisher : Elsevier
Page : 374 pages
File Size : 45,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323153591

Get Book

Quantitative Coherent Imaging by J.M. Blackledge Pdf

Quantitative Coherent Imaging: Theory, Methods and Some Applications discusses the principles of interpreting the structure and material properties of objects by the way in which they scatter electromagnetic and acoustic radiation. It presents an account of the fundamental physical principles which are common to nearly all imaging systems. The book is divided into three parts. Part One deals with the mathematical and computational background to the subject. Part Two discusses the theory of quantitative coherent imaging, presenting the theoretical foundations used in a variety of applications. It looks at both acoustic and electromagnetic imaging systems. Part Three examines some of the data-processing techniques which are common to most types of imagery. It cites methods of deconvolution, image enhancement, and noise reduction. This book caters to the reader interested in different fields of research in imaging science. It explains the principles of coherent imaging and provides a text that covers the theoretical foundations of imaging science in an integrated form.

Author : Gabriel Popescu
Publisher : McGraw Hill Professional
Page : 384 pages
File Size : 55,7 Mb
Release : 2011-03-14
Category : Technology & Engineering
ISBN : 9780071663434

Get Book

Quantitative Phase Imaging of Cells and Tissues by Gabriel Popescu Pdf

Cutting-edge quantitative phase imaging techniques and their applications Filled with unique, full-color images taken by advanced quantitative phase imaging (QPI), Quantitative Phase Imaging of Cells and Tissues thoroughly explores this innovative technology and its biomedical applications. An introductory background on optical imaging and traditional optical microscopy is included to illustrate concept development. The book explains how various visualization modalities can be obtained by numerical calculations. This authoritative resource reveals how to take full advantage of the unprecedented capabilities of QPI, such as rendering scattering properties of minute subcellular structures and nanoscale fluctuations in live cells. Coverage includes: Groundwork Spatiotemporal field correlations Image characteristics Light microscopy Holography Point scanning QPI methods Principles of full-field QPI Off-axis full-field methods Phase-shifting techniques Common-path methods White light techniques Fourier transform light scattering (FTLS) Current trends in QPI

Author : International Atomic Energy Agency
Publisher : Unknown
Page : 59 pages
File Size : 48,9 Mb
Release : 2014
Category : Medical
ISBN : 9201415109

Get Book

Quantitative Nuclear Medicine Imaging by International Atomic Energy Agency Pdf

This publication reviews the current state of the art of image quantification and provides a solid background of tools and methods to medical physicists and other related professionals who are faced with quantification of radionuclide distribution in clinical practice. It describes and analyses the physical effects that degrade image quality and affect the accuracy of quantification, and describes methods to compensate for them in planar, single-photon emission computed tomography (SPECT) and positron emission tomography (PET) images.

Author : Hernan Jara
Publisher : World Scientific Publishing Company Incorporated
Page : 250 pages
File Size : 55,9 Mb
Release : 2012-10-31
Category : Medical
ISBN : 981429523X

Get Book

Theory of Quantitative Magnetic Resonance Imaging by Hernan Jara Pdf

qMRI is a rapidly evolving scientific field of high current interest because it has the potential of radically changing the clinical and research practices of magnetic resonance imaging (MRI). This focuses solely on the theoretical aspects of qMRI, which are treated and analyzed at three different spatial scales, specifically: i) the quantum physics scale of individual spins; ii) the semi-classical physics scale of spin packets; and iii) the imaging scale of voxels. Topics are presented paying particular attention to theoretical unification and mathematical uniformity.

Author : Pietro Ferraro,Adam Wax,Zeev Zalevsky
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 47,9 Mb
Release : 2011-02-09
Category : Science
ISBN : 9783642158131

Get Book

Coherent Light Microscopy by Pietro Ferraro,Adam Wax,Zeev Zalevsky Pdf

This book deals with the latest achievements in the field of optical coherent microscopy. While many other books exist on microscopy and imaging, this book provides a unique resource dedicated solely to this subject. Similarly, many books describe applications of holography, interferometry and speckle to metrology but do not focus on their use for microscopy. The coherent light microscopy reference provided here does not focus on the experimental mechanics of such techniques but instead is meant to provide a users manual to illustrate the strengths and capabilities of developing techniques. The areas of application of this technique are in biomedicine, medicine, life sciences, nanotechnology and materials sciences.

Author : Luis Martí-Bonmatí,Angel Alberich-Bayarri
Publisher : Springer
Page : 316 pages
File Size : 42,7 Mb
Release : 2016-11-03
Category : Medical
ISBN : 9783319435046

Get Book

Imaging Biomarkers by Luis Martí-Bonmatí,Angel Alberich-Bayarri Pdf

This is the first book to cover all aspects of the development of imaging biomarkers and their integration into clinical practice, from the conceptual basis through to the technical aspects that need to be considered in order to ensure that medical imaging can serve as a powerful quantification instrument capable of providing valuable information on organ and tissue properties. The process of imaging biomarker development is considered step by step, covering proof of concept, proof of mechanism, image acquisition, image preparation, imaging biomarker analysis and measurement, detection of measurement biases (proof of principle), proof of efficacy and effectiveness, and reporting of results. Sources of uncertainty in the accuracy and precision of measurements and pearls and pitfalls in gold standards and biological correlation are discussed. In addition, practical use cases are included on imaging biomarker implementation in brain, oncologic, cardiovascular, musculoskeletal, and abdominal diseases. The authors are a multidisciplinary team of expert radiologists and engineers, and the book will be of value to all with an interest in the quantitative imaging of biomarkers in personalized medicine.

Author : Guido Buonincontri,Joshua Kaggie,Martin Graves
Publisher : Springer Nature
Page : 124 pages
File Size : 49,9 Mb
Release : 2022-05-31
Category : Technology & Engineering
ISBN : 9783031016677

Get Book

Fast Quantitative Magnetic Resonance Imaging by Guido Buonincontri,Joshua Kaggie,Martin Graves Pdf

Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challenges remain. The primary source of contrast in MRI images are the various relaxation parameters associated with the nuclear magnetic resonance (NMR) phenomena upon which MRI is based. Although it is possible to quantify these relaxation parameters (qMRI) they are rarely used in the clinic, and radiological interpretation of images is primarily based upon images that are relaxation time weighted. The clinical adoption of qMRI is mainly limited by the long acquisition times required to quantify each relaxation parameter as well as questions around their accuracy and reliability. More specifically, the main limitations of qMRI methods have been the difficulty in dealing with the high inter-parameter correlations and a high sensitivity to MRI system imperfections. Recently, new methods for rapid qMRI have been proposed. The multi-parametric models at the heart of these techniques have the main advantage of accounting for the correlations between the parameters of interest as well as system imperfections. This holistic view on the MR signal makes it possible to regress many individual parameters at once, potentially with a higher accuracy. Novel, accurate techniques promise a fast estimation of relevant MRI quantities, including but not limited to longitudinal (T1) and transverse (T2) relaxation times. Among these emerging methods, MR Fingerprinting (MRF), synthetic MR (syMRI or MAGIC), and T1‒T2 Shuffling are making their way into the clinical world at a very fast pace. However, the main underlying assumptions and algorithms used are sometimes different from those found in the conventional MRI literature, and can be elusive at times. In this book, we take the opportunity to study and describe the main assumptions, theoretical background, and methods that are the basis of these emerging techniques. Quantitative transient state imaging provides an incredible, transformative opportunity for MRI. There is huge potential to further extend the physics, in conjunction with the underlying physiology, toward a better theoretical description of the underlying models, their application, and evaluation to improve the assessment of disease and treatment efficacy.

Author : Heidi Johansen-Berg,Timothy E.J. Behrens
Publisher : Academic Press
Page : 632 pages
File Size : 44,5 Mb
Release : 2013-11-04
Category : Medical
ISBN : 9780124055094

Get Book

Diffusion MRI by Heidi Johansen-Berg,Timothy E.J. Behrens Pdf

Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain Provides practical advice on running an experiment Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience Full color throughout

Author : Richard E. Carson,Margaret E. Daube-Witherspoon,Peter Herscovitch
Publisher : Academic Press
Page : 544 pages
File Size : 48,7 Mb
Release : 1998-08-28
Category : Medical
ISBN : UOM:39015045622928

Get Book

Quantitative Functional Brain Imaging with Positron Emission Tomography by Richard E. Carson,Margaret E. Daube-Witherspoon,Peter Herscovitch Pdf

This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers

Author : Nandita Maria deSouza,Laure S. Fournier,Daniela Elena Oprea-Lager
Publisher : Frontiers Media SA
Page : 124 pages
File Size : 45,5 Mb
Release : 2022-08-19
Category : Medical
ISBN : 9782889746767

Get Book

Quantitative Imaging for Clinical Decisions by Nandita Maria deSouza,Laure S. Fournier,Daniela Elena Oprea-Lager Pdf

Author : John James Frost,Henry N. Wagner (Jr.)
Publisher : Raven Press (ID)
Page : 232 pages
File Size : 49,5 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015017928998

Get Book

Quantitative Imaging by John James Frost,Henry N. Wagner (Jr.) Pdf