Rare Immune Mediated Diseases Novel Insights Into Underlying Mechanisms And Therapeutic Approaches

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Defects in Regulation: How, Where and When The Immune System Can Go Wrong

Author : Ger Rijkers,Carlo Riccardi,Frans G. M. Kroese
Publisher : Frontiers Media SA
Page : 117 pages
File Size : 44,7 Mb
Release : 2022-02-03
Category : Medical
ISBN : 9782889714469

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Defects in Regulation: How, Where and When The Immune System Can Go Wrong by Ger Rijkers,Carlo Riccardi,Frans G. M. Kroese Pdf

Advances in neural reprogramming, disease modeling and therapeutic insights

Author : Shong Lau,Fred H. Gage,Shani Stern,Janelle Drouin-Ouellet
Publisher : Frontiers Media SA
Page : 175 pages
File Size : 43,5 Mb
Release : 2023-08-21
Category : Science
ISBN : 9782832532218

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Advances in neural reprogramming, disease modeling and therapeutic insights by Shong Lau,Fred H. Gage,Shani Stern,Janelle Drouin-Ouellet Pdf

Genetics of Inflammatory and Immune Diseases

Author : Xianyong Yin,Yonghu Sun,Yunqing Ren
Publisher : Frontiers Media SA
Page : 223 pages
File Size : 50,8 Mb
Release : 2024-01-23
Category : Science
ISBN : 9782832543344

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Genetics of Inflammatory and Immune Diseases by Xianyong Yin,Yonghu Sun,Yunqing Ren Pdf

Genetics of Inflammatory and Immune Diseases

Advances in Pathogenesis, Etiology, and Therapies for Ankylosing Spondylitis

Author : Jieruo Gu,David Yu,James Cheng-Chung Wei
Publisher : Frontiers Media SA
Page : 106 pages
File Size : 44,8 Mb
Release : 2022-02-10
Category : Medical
ISBN : 9782889743209

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Advances in Pathogenesis, Etiology, and Therapies for Ankylosing Spondylitis by Jieruo Gu,David Yu,James Cheng-Chung Wei Pdf

The Autoimmune Brain

Author : David S. Younger
Publisher : Rowman & Littlefield
Page : 289 pages
File Size : 49,7 Mb
Release : 2019-11-10
Category : Health & Fitness
ISBN : 9781538117712

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The Autoimmune Brain by David S. Younger Pdf

There are millions of people who experience issues related to brain health—depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain—yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or anti-anxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their age—from children to teens or seniors—people and their loved ones are frustrated, scared, and confused by their continued poor health. Countless others display severe psychiatric symptoms that seem to come out of nowhere, ranging from tics, obsessive-compulsive behaviors and anxiety, to depression, bipolar-like mood swings, and even borderline personality disorder and suicidal ideas. Sometimes, the people affected are the only ones that notices a change to the way they think or feel, and they suffer in silence. Or, they reach out to try to get help, and are all too frequently misdiagnosed. David Younger, a world-renowned physician, provides relief to these patients and their families. His diagnostic techniques and treatment protocols will help readers identify the true cause of their symptoms and put them on a clear path to healing so they no longer feel unbalanced, out of control, forgetful, and exhausted. The Autoimmune Brain connects common brain health symptoms to the changes in the immune system, and particularly bacterial, viral, and parasitic infections. Younger explains his groundbreaking research and adds a new component: how traumatic stress (whether physical or emotional) and genetics affects this same triad as inextricable factors in initiating disease and brain health symptoms. In fact, a change in personality, behavior, coping style, and one’s emotional state may be the first clue that there is a health problem brewing somewhere else in the body. Readers will find new answers to troubling conditions, including: Alzheimer’s disease; Anxiety; Arthritis; Autism; Autonomic disturbances; Bacterial and viral infections; Bipolar Disorder; Cancer; Celiac disease and gluten intolerances; Chronic Fatigue Syndrome (now referred to as Systemic Exertion Intolerance Disease); Chronic Pain; Dementia; Depression; Endocrine Disorders; Immune modulatory therapy using IVIg; Lyme disease and co-infections; Mast cell activation syndrome; Medical cannabis; Obsessive Compulsive Disorder; Orthostatic hypotension; Peripheral Neuropathy; Porphyria; Post-Traumatic Stress Disorder; and Postural orthostatic tachycardia.

Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases

Author : Richard K. Burt,Dominique Farge,Milton A. Ruiz,Riccardo Saccardi,John A. Snowden
Publisher : CRC Press
Page : 687 pages
File Size : 53,6 Mb
Release : 2021-11-17
Category : Medical
ISBN : 9781351364768

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Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases by Richard K. Burt,Dominique Farge,Milton A. Ruiz,Riccardo Saccardi,John A. Snowden Pdf

This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune diseases versus current conventional treatments. Arranged by disease, the text provides a comprehensive guide to HSCT for all types of autoimmune/immune disorders including monogenetic autoimmune diseases; autoimmune aplastic anemia; neurologic immune diseases including multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, and stiff person syndrome; rheumatologic diseases such as systemic sclerosis and systemic lupus erythematosus; dermatologic diseases such as pemphigus; gastrointestinal disorders such as Crohn’s disease and celiac disease; and immune-mediated endocrinologic disease type I diabetes mellitus. Guidance is provided on the transplantation technique, cell collection and processing, conditioning regimens, infections, and early and late complications. Key Features Outlines therapies and techniques for HSCT for autoimmune diseases Discusses the advantages of HSCT over conventional therapies Reviews the entire process of stem cell therapy from harvest and ethics to indications, efficacy, and regulatory oversight

Immune-Related Non-Communicable Diseases in Africa

Author : Mohamed-Ridha Barbouche,Brian Stephen Eley
Publisher : Frontiers Media SA
Page : 116 pages
File Size : 54,8 Mb
Release : 2022-02-17
Category : Medical
ISBN : 9782889744190

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Immune-Related Non-Communicable Diseases in Africa by Mohamed-Ridha Barbouche,Brian Stephen Eley Pdf

Case Studies in Immunology

Author : Raif Geha,Luigi Notarangelo
Publisher : Garland Science
Page : 385 pages
File Size : 43,5 Mb
Release : 2016-02-05
Category : Medical
ISBN : 9781317390008

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Case Studies in Immunology by Raif Geha,Luigi Notarangelo Pdf

Case Studies in Immunology, Seventh Edition is intended for medical students and undergraduate and graduate students in immunology. It presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms o

Textbook of Autoinflammation

Author : Philip J. Hashkes,Ronald M. Laxer,Anna Simon
Publisher : Springer
Page : 820 pages
File Size : 54,5 Mb
Release : 2019-02-13
Category : Medical
ISBN : 9783319986050

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Textbook of Autoinflammation by Philip J. Hashkes,Ronald M. Laxer,Anna Simon Pdf

This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2005

Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Page : 1890 pages
File Size : 47,5 Mb
Release : 2004
Category : United States
ISBN : MINN:31951D02570187S

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Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2005 by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies Pdf

Immune-Mediated Myopathies and Neuropathies

Author : Balan Louis Gaspar
Publisher : Springer Nature
Page : 296 pages
File Size : 40,7 Mb
Release : 2023-02-21
Category : Medical
ISBN : 9789811984211

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Immune-Mediated Myopathies and Neuropathies by Balan Louis Gaspar Pdf

The book covers all aspects of immune-mediated diseases of the muscle and nerve, which are a group of complex diseases, whose diagnosis needs a team of specialists in the field of neuropathology, immunopathology, neurology, and rheumatology. Nerve and muscle biopsy evaluation is invaluable in distinguishing immune-mediated from etiologies and therefore, despite being invasive, pathological evaluation of nerve and muscle has stood the test of time. Chapters cover all the essential aspects of each disease entity viz. the pathogenesis, clinical features, diagnostic armamentarium, and guidelines for diagnosis and management. It is supplemented with full-colorful illustrations and photomicrographs for better comprehension. It includes a chapter highlighting the current progress in the field of immune-mediated myopathies and neuropathies as it is a rapidly evolving field with the addition of many new entities. This clinically oriented book serves as a primer for general histopathologists as well as a practice guide for neuropathologists. It is also relevant for neurologists and rheumatologists and encourages young medical students, residents, and research scholars in the field of neuropathology, neurology, and rheumatology to get involved in active research.

Whitcup and Nussenblatt's Uveitis

Author : Scott M. Whitcup,H. Nida Sen
Publisher : Elsevier Health Sciences
Page : 432 pages
File Size : 45,8 Mb
Release : 2021-03-31
Category : Medical
ISBN : 9780323789592

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Whitcup and Nussenblatt's Uveitis by Scott M. Whitcup,H. Nida Sen Pdf

Comprehensive and readable, Whitcup and Nussenblatt's Uveitis, 5th Edition, covers every aspect of this complex subspecialty in a single convenient volume. This clinically relevant guide covers the medical, pharmacological, and surgical treatment of uveitis in a visually rich, full-color format, offering a complete overview for today’s clinicians. New and updated case studies, key points boxes, and more than 400 images and graphics highlight major clinical points and provide insight into real situations that you can apply in practice. Features multiple chapters on diagnostic approach to help you meet the challenge of making accurate diagnoses. Reflects advancements and new developments on all aspects of uveitis including new medical and surgical treatments. Covers key topics such as the use of PCR in diagnostic testing, cataract surgery in patients with uveitis, the use of OCT in diagnosis and treatment, new infectious causes of uveitis (including Zika and Ebola), and novel treatments for inflammatory eye disease. Includes new clinical photographs, illustrations, and OCT images throughout. Reviews new randomized clinical trials of new uveitis therapy, as well as the approach to patients with HIV and HIV-associated ocular diseases including CMV retinitis and immune recovery uveitis. Provides expanded information on masquerade syndromes with important tips on diagnosis and management of intraocular lymphoma.

Adverse Effects of Vaccines

Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines
Publisher : National Academies Press
Page : 894 pages
File Size : 44,9 Mb
Release : 2012-04-26
Category : Medical
ISBN : 9780309214353

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Adverse Effects of Vaccines by Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines Pdf

In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

Immunogenetics: A Molecular and Clinical Overview

Author : Muneeb U. Rehman,Azher Arafah,Md. Niamat Ali,Shafat Ali
Publisher : Academic Press
Page : 412 pages
File Size : 40,7 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9780323903356

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Immunogenetics: A Molecular and Clinical Overview by Muneeb U. Rehman,Azher Arafah,Md. Niamat Ali,Shafat Ali Pdf

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. Contains exclusive information about research on immunogenetics from around the globe Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner