Real World Experience With Cftr Modulator Therapy

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Real-world experience with CFTR modulator therapy

Author : Burkhard Tümmler,Pierre-Régis Burgel
Publisher : Frontiers Media SA
Page : 151 pages
File Size : 43,7 Mb
Release : 2023-12-04
Category : Science
ISBN : 9782832540244

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Real-world experience with CFTR modulator therapy by Burkhard Tümmler,Pierre-Régis Burgel Pdf

Cystic Fibrosis

Author : Dennis Wat,Dilip Nazareth
Publisher : Unknown
Page : 136 pages
File Size : 50,6 Mb
Release : 2020
Category : Electronic
ISBN : 1838809686

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Cystic Fibrosis by Dennis Wat,Dilip Nazareth Pdf

Cystic Fibrosis - Heterogeneity and Personalized Treatment provides the latest research and clinical evidence for clinicians, scientists and researchers involved in the care of patients with cystic fibrosis (CF). This book outlines the burden of the CF microbiome, utilisation of CF registries to impact future care, the sequelae of hepatobiliary complication, the use of upcoming technologies to provide patient-centred care, and provides an overview of cystic fibrosis transmembrane regulator (CFTR) modulators. Looking after patients with CF is highly rewarding, allowing those of us to combine our dedication and problem-solving skills to create a personalized approach. This book is invaluable for those involved in the care of CF patients.

Advances in Cystic Fibrosis, An Issue of Clinics in Chest Medicine, E-Book

Author : Clemente J. Britto,Jennifer L. Taylor-Cousar
Publisher : Elsevier Health Sciences
Page : 281 pages
File Size : 46,6 Mb
Release : 2022-11-09
Category : Medical
ISBN : 9780323849623

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Advances in Cystic Fibrosis, An Issue of Clinics in Chest Medicine, E-Book by Clemente J. Britto,Jennifer L. Taylor-Cousar Pdf

In this issue of Clinics in Chest Medicine, guest editors Drs. Clemente J. Britto and Jennifer L. Taylor-Cousar bring their considerable expertise to Advances in Cystic Fibrosis. Top experts in the field cover key topics such as genetics of cystic fibrosis (CF): clinical implications; innate and adaptive immunity in CF; novel applications of biomarkers and personalized medicine to define the spectrum of CF; emerging approaches to understand CF pathogenesis; and more. Contains 18 relevant, practice-oriented topics including novel approaches to multidrug resistant infections in CF; clinical outcomes of highly-effective modulator therapy; nontuberculous mycobacterial infections in CF; management of mental health in CF; sexual and reproductive health in CF; nutritional management in CF; transitions of care in CF; and more. Provides in-depth clinical reviews on advances in cystic fibrosis, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Cystic Fibrosis

Author : Dennis Wat,Dilip Nazareth
Publisher : BoD – Books on Demand
Page : 138 pages
File Size : 51,8 Mb
Release : 2020-07-08
Category : Medical
ISBN : 9781789841459

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Cystic Fibrosis by Dennis Wat,Dilip Nazareth Pdf

Cystic Fibrosis - Heterogeneity and Personalized Treatment provides the latest research and clinical evidence for clinicians, scientists and researchers involved in the care of patients with cystic fibrosis (CF). This book outlines the burden of the CF microbiome, utilisation of CF registries to impact future care, the sequelae of hepatobiliary complication, the use of upcoming technologies to provide patient-centred care, and provides an overview of cystic fibrosis transmembrane regulator (CFTR) modulators. Looking after patients with CF is highly rewarding, allowing those of us to combine our dedication and problem-solving skills to create a personalized approach. This book is invaluable for those involved in the care of CF patients.

Hodson and Geddes' Cystic Fibrosis

Author : Andrew Bush,Margarida D. Amaral,Jane C. Davies,Nicholas J. Simmonds,Jennifer L. Taylor-Cousar,Sarath C. Ranganathan
Publisher : CRC Press
Page : 747 pages
File Size : 55,8 Mb
Release : 2023-11-20
Category : Medical
ISBN : 9781000988536

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Hodson and Geddes' Cystic Fibrosis by Andrew Bush,Margarida D. Amaral,Jane C. Davies,Nicholas J. Simmonds,Jennifer L. Taylor-Cousar,Sarath C. Ranganathan Pdf

Cystic Fibrosis has seen dramatic advances in treatment since the last edition, including targeted cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators for most CFTR gene abnormalities. This new fifth edition is an update and expansion of the rapid clinical and scientific advances in improving prognosis, and the impact of COVID-19, all of which has transformed conventional models of care. It covers basic science, such as how detailed understanding of the biology of the CFTR gene and protein has led to novel and beneficial therapies, as well as all aspects of clinical management in high-, middle- and low-income settings and the voices of individuals with CF from across the world. It will be a useful reference for clinicians, including all levels of trainees, across the whole multidisciplinary team, scientists and students. Key Features • Follows an appealing organization of chapters, by developing fundamental knowledge of the reader before moving on to more complex or developing topics. • Presents a comprehensive, authoritative and up-to-date text, integrating fundamental science and clinical aspects of cystic fibrosis providing an attractive read for clinicians, trainee doctors and scientists. • Draws on global expertise and reflects best evidence-based practice from experts conducting cutting-edge clinical and basic science research from around the world.

Ion Channels as Targets in Drug Discovery

Author : Gary Stephens
Publisher : Springer Nature
Page : 540 pages
File Size : 40,5 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9783031521973

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Ion Channels as Targets in Drug Discovery by Gary Stephens Pdf

The Transition of Respiratory Care: from Child to Adult

Author : Alexandra M. Nanzer,Peter J. Barry,Brian D. Kent
Publisher : European Respiratory Society
Page : 191 pages
File Size : 44,7 Mb
Release : 2024-06-01
Category : Medical
ISBN : 9781849841795

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The Transition of Respiratory Care: from Child to Adult by Alexandra M. Nanzer,Peter J. Barry,Brian D. Kent Pdf

One in five adolescents have special healthcare needs; one in 10 face limitations to daily activities due to chronic illness or disability. Taken alongside the ever-changing societal landscape and the multifaceted psychological aspects of adolescence, these statistics underline the need to recognise adolescents and young adults as a distinct patient population with unique healthcare needs. This Monograph addresses this need. Opening with chapters that discuss health inequalities, adolescent psychology and treatment adherence, the book goes on to cover specific respiratory diseases and the requirements of their adolescent subjects. Readers will find this Monograph a useful and interesting insight into adolescent health.

Kendig and Wilmott’s Disorders of the Respiratory Tract in Children

Author : Andrew Bush,Robin R Deterding,Albert Li,Felix Ratjen,Peter Sly,Heather Zar,Robert W. Wilmott
Publisher : Elsevier Health Sciences
Page : 1584 pages
File Size : 47,7 Mb
Release : 2023-08-21
Category : Medical
ISBN : 9780323829168

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Kendig and Wilmott’s Disorders of the Respiratory Tract in Children by Andrew Bush,Robin R Deterding,Albert Li,Felix Ratjen,Peter Sly,Heather Zar,Robert W. Wilmott Pdf

Extensively revised from cover to cover, Kendig and Wilmott's Disorders of the Respiratory Tract in Children, 10th Edition, continues to be your #1 choice for reliable, up-to-date information on all aspects of pediatric respiratory disorders. This highly respected reference is accessible to specialists and primary care providers alike, with coverage of both common and less common respiratory problems found in the newborn and child. Detailed and thorough, this edition covers basic science and its relevance to today’s clinical issues as well as treatment, management, and outcomes information, making it an ideal resource for day-to-day practice as well as certification or recertification review and other professional examinations such as pHERMES. Offers an international perspective on the whole spectrum of the specialty, including a robust video library with demonstrations of key procedures and bronchoscopic views. Uses a consistent format with succinct, bulleted text, and contains abundant tables and figures, chapter summaries, and more than 500 full-color images to convey key information in an easy-to-digest manner. Contains eleven new chapters and discusses timely topics such as big data and -omics in respiratory disease, COVID-19, obesity and its consequences, and vaping and nicotine addiction among children and young people. Provides up-to-date instruction on key procedures, such as bronchoscopy and pulmonary function testing. Highlights the knowledge and expertise of nearly 90 new authors who are global experts in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery.

Antimicrobial peptides and their druggability, bio-safety, stability, and resistance

Author : Jianhua Wang,Octavio Luiz Franco,Rustam Aminov,Cesar de la Fuente-Nunez,Guangshun Wang
Publisher : Frontiers Media SA
Page : 322 pages
File Size : 52,9 Mb
Release : 2024-05-29
Category : Science
ISBN : 9782832549810

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Antimicrobial peptides and their druggability, bio-safety, stability, and resistance by Jianhua Wang,Octavio Luiz Franco,Rustam Aminov,Cesar de la Fuente-Nunez,Guangshun Wang Pdf

Anion Channels and Transporters

Author : Christoph Fahlke
Publisher : Springer Nature
Page : 368 pages
File Size : 52,5 Mb
Release : 2024-01-04
Category : Medical
ISBN : 9783031513466

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Anion Channels and Transporters by Christoph Fahlke Pdf

This book provides an overview on recent progress in anion channels and transporters. It covers multiple scales of analysis ranging from studying the molecular basis of function at atomic resolution to cellular consequences to channel/transporter dysfunction and approaches to correct such processes by pharmacological intervention. Similar anion channels and transporters are expressed in multiple tissues – often fulfilling similar cellular tasks, but also clearly distinct functions. The aim is to combine work on multiple cell and organ systems.

Curing Genetic Diseases through Genome Reprogramming

Author : Anonim
Publisher : Academic Press
Page : 560 pages
File Size : 49,6 Mb
Release : 2021-06-24
Category : Science
ISBN : 9780323853026

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Curing Genetic Diseases through Genome Reprogramming by Anonim Pdf

Curing Genetic Diseases through Genome Reprogramming, Volume 182 captures an historic moment in the field of gene therapy—the dawn of a new age in which the dream of curing genetic diseases has become realizable. The volume presents the most clinically advanced gene therapy and genome editing approaches for the treatment of genetic diseases in specific organs, including difficult therapeutic targets, futuristic ideas of genetic interventions, and large scale human genome repair. An initial chapter addresses the complex ethical aspects involved in the very idea of modifying the human genome. Provides a comprehensive view of gene therapy and genome editing technologies, including epigenetic editing Describes the state-of-the-art and future directions for the treatment of genetic diseases, also considering economical aspects Presents chapters that each give a thorough review of a specific disease, target organ or visionary approach, including ethical considerations

Rare Diseases of the Respiratory System

Author : Thomas O.F. Wagner,Marc Humbert,Marlies Wijsenbeek,Michael Kreuter
Publisher : European Respiratory Society
Page : 399 pages
File Size : 42,8 Mb
Release : 2023-06-01
Category : Medical
ISBN : 9781849841672

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Rare Diseases of the Respiratory System by Thomas O.F. Wagner,Marc Humbert,Marlies Wijsenbeek,Michael Kreuter Pdf

Diagnosing rare diseases can be challenging, and treating these conditions is complex because of their often quite specific needs and treatment options. To address this, the European Respiratory Society (ERS) has published Rare Diseases of the Respiratory System. Structured into thematic sections, the book covers: the identification of rare diseases of the respiratory system and their differential diagnosis; rare diseases of the lung interstitium; rare diseases of the airways or alveoli; and rare pulmonary vascular diseases. The Guest Editors and authors belong to and/or support the vision and mission of the European Reference Network for Rare Diseases of the Respiratory System (ERN-LUNG), which offers expert support to both patients and professionals. As such, this comprehensive book will prove an excellent resource for healthcare professionals, researchers and students interested in rare diseases of the respiratory system.

Biotechnology and Drug Development for Targeting Human Diseases

Author : Israel Valencia Quiroz
Publisher : Bentham Science Publishers
Page : 235 pages
File Size : 44,8 Mb
Release : 2024-03-14
Category : Science
ISBN : 9789815223170

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Biotechnology and Drug Development for Targeting Human Diseases by Israel Valencia Quiroz Pdf

Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease. Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology. Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource. Readership Students and professionals in the fields of biotechnology and pharmacology.

Kendig's Disorders of the Respiratory Tract in Children E-Book

Author : Robert W. Wilmott,Andrew Bush,Robin R Deterding,Felix Ratjen,Peter Sly,Heather Zar,Albert Li
Publisher : Elsevier Health Sciences
Page : 1150 pages
File Size : 46,6 Mb
Release : 2018-01-17
Category : Medical
ISBN : 9780323555951

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Kendig's Disorders of the Respiratory Tract in Children E-Book by Robert W. Wilmott,Andrew Bush,Robin R Deterding,Felix Ratjen,Peter Sly,Heather Zar,Albert Li Pdf

Now in a fully updated 9th Edition, Kendig's Disorders of the Respiratory Tract in Children, by Drs. Robert Wilmott, Andrew Bush, Robin Deterding, and Felix Ratjen, continues to provide authoritative, evidence-based information to residents, fellows, and practitioners in this wide-ranging specialty. Bringing key knowledge from global experts together in one easy-to-understand volume, it covers everything from the latest basic science and its relevance to today’s clinical issues, to improving patient outcomes for the common and rare respiratory problems found in newborns and children worldwide. Uses succinct, straightforward text, numerous tables and figures, summaries at the end of each chapter, and more than 500 full-color images to convey key information in an easy-to-digest manner. Contains new chapters reflecting expanding knowledge on the respiratory complications of Down syndrome and other genetic disorders, modern molecular therapies for cystic fibrosis and asthma, and pulmonary embolism and thromboembolic disease. Features a new templated format with more descriptive headings and bulleted text for quick reference and navigation. Covers today’s key issues, including the genetic basis of respiratory disease, new and emerging respiratory infections, interstitial lung diseases in infants and young children, technology and diagnostic techniques for pulmonary function tests, emerging lung infections, and new therapies for cystic fibrosis and asthma. Provides up-to-date instruction on important procedures, such as bronchoscopy and pulmonary function testing. Highlights the knowledge and expertise of three new editors, as well as more than 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery.

Cystic Fibrosis

Author : Stephanie Duggins Davis,Margaret Rosenfeld,James Chmiel
Publisher : Springer Nature
Page : 525 pages
File Size : 47,6 Mb
Release : 2020-05-21
Category : Medical
ISBN : 9783030423827

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Cystic Fibrosis by Stephanie Duggins Davis,Margaret Rosenfeld,James Chmiel Pdf

This book provides a comprehensive overview of the multisystem disease, cystic fibrosis, for both pediatric and adult patients. Written by experts in the field, the text outlines the progressive nature of CF as well as the impact of this autosomal recessive disease on the respiratory, gastrointestinal, endocrine, rheumatologic, and renal systems, as well as the patient’s mental health. The book begins with a chapter describing the history of cystic fibrosis and how the face of this life-shortening disease has changed over the past several decades. The following chapters elucidate the pathophysiology of how cystic fibrosis impacts each organ system. Current management and therapeutics are detailed with step-by-step guidelines for clinicians. This book is unique in that it highlights the entire person, not just the respiratory system, with detailed inclusion of the patient perspectives throughout, informing practice standards and considerations. This is an ideal guide for pediatric and adult physicians who care for patients with cystic fibrosis, as well as respiratory therapists, physical therapists, nurses, nutritionists, and pharmacists who care for these patients.