Recent Advances In Psychiatry From Psycho Neuro Immunology Research Autoimmunencephalitis Autoimmune Encephalopathy Mild Encephalitis

Author : Karl Bechter,David Brown,Souhel Najjar
Publisher : Frontiers Media SA
Page : 189 pages
File Size : 40,8 Mb
Release : 2019-08-12
Category : Electronic
ISBN : 9782889459506

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Recent Advances in Psychiatry from Psycho-Neuro-Immunology Research: Autoimmunencephalitis, Autoimmune-Encephalopathy, Mild Encephalitis by Karl Bechter,David Brown,Souhel Najjar Pdf

Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms may contribute to a subset of patients currently diagnosed as having treatment-resistant SMDs such as schizophrenia and major depressive disorder. Additionally, mounting data indicate that various infections can serve as an immunological trigger of aberrant immune responses, presumably by causing release of excess neural antigen, thereby giving rise to NSAs or aberrant immune cellular responses to give rise to primary or secondary psychiatric disorders such as schizophrenia and those associated with AE, respectively. Collectively, these findings support the “mild encephalitis” hypothesis of SMD. The significant overlap among AE-associated psychosis, systemic autoimmune disorder-associated psychosis, and psychotic disorders associated with pathological processes involving inflammation and immune dysregulation has also prompted some authors to adopt the term “autoimmune psychosis” (AP). This term reflects that this psychosis subtype is mechanistically linked to complex neuroimmune and inflammatory signalling abnormalities that can be responsive to early immunomodulatory treatment. It also suggests that a subset of AP might represent an incomplete or “forme fruste” subtype of AE presenting with dominant or pure psychiatric symptoms mimicking primary psychiatric illnesses. Because data indicate that delayed diagnosis and treatment may lead to permanent sequelae, early recognition of AP utilizing neurodiagnostic workup (e.g., CSF analysis, neuroimaging, and EEG) and its early treatment with appropriate immunotherapy are paramount to a meaningful recovery. This eBook will provide an overview of the current knowledge and research areas from epidemiology, risk factors and diagnosis to the management of these conditions, in this rapidly emerging field, helping to bridge the gaps in knowledge that currently exist in the disciplines of Psychiatry, Neurology, and Neuroimmunology.

Author : Vida Demarin
Publisher : Springer Nature
Page : 140 pages
File Size : 46,7 Mb
Release : 2020-02-13
Category : Medical
ISBN : 9783030386061

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Mind and Brain by Vida Demarin Pdf

This book discusses the link between the brain and the mind. Adopting an evidence-based neuropsychiatry approach while also touching on philosophical aspects, it examines the association between diseases of the brain and mental health, offering comprehensive insights into the emerging new discipline of psychoneuroendocrinoimmunology and its translation to clinical practice. The book particularly focuses on brain plasticity and on explaining the ability of the brain to learn new pathways in everyday situations and at the same time improve creativity. Written by clinicians and leading experts in the field of brain physiology and pathology, this book is a valuable resource for medical professionals and postgraduate students.

Author : Susannah Cahalan
Publisher : Penguin UK
Page : 288 pages
File Size : 50,6 Mb
Release : 2012-11-13
Category : Biography & Autobiography
ISBN : 9780141975351

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Brain On Fire: My Month of Madness by Susannah Cahalan Pdf

'My first serious blackout marked the line between sanity and insanity. Though I would have moments of lucidity over the coming days and weeks, I would never again be the same person ...' Susannah Cahalan was a happy, clever, healthy twenty-four-year old. Then one day she woke up in hospital, with no memory of what had happened or how she had got there. Within weeks, she would be transformed into someone unrecognizable, descending into a state of acute psychosis, undergoing rages and convulsions, hallucinating that her father had murdered his wife; that she could control time with her mind. Everything she had taken for granted about her life, and who she was, was wiped out. Brain on Fire is Susannah's story of her terrifying descent into madness and the desperate hunt for a diagnosis, as, after dozens of tests and scans, baffled doctors concluded she should be confined in a psychiatric ward. It is also the story of how one brilliant man, Syria-born Dr Najar, finally proved - using a simple pen and paper - that Susannah's psychotic behaviour was caused by a rare autoimmune disease attacking her brain. His diagnosis of this little-known condition, thought to have been the real cause of devil-possessions through history, saved her life, and possibly the lives of many others. Cahalan takes readers inside this newly-discovered disease through the progress of her own harrowing journey, piecing it together using memories, journals, hospital videos and records. Written with passionate honesty and intelligence, Brain on Fire is a searingly personal yet universal book, which asks what happens when your identity is suddenly destroyed, and how you get it back. 'With eagle-eye precision and brutal honesty, Susannah Cahalan turns her journalistic gaze on herself as she bravely looks back on one of the most harrowing and unimaginable experiences one could ever face: the loss of mind, body and self. Brain on Fire is a mesmerizing story' -Mira Bartók, New York Times bestselling author of The Memory Palace Susannah Cahalan is a reporter on the New York Post, and the recipient of the 2010 Silurian Award of Excellence in Journalism for Feature Writing. Her writing has also appeared in the New York Times, and is frequently picked up by the Daily Mail, Gawker, Gothamist, AOL and Yahoo among other news aggregrator sites.

Author : Charlotte Watts
Publisher : Singing Dragon
Page : 394 pages
File Size : 49,8 Mb
Release : 2022-10-21
Category : Health & Fitness
ISBN : 9781839970887

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Yoga and Somatics for Immune and Respiratory Health by Charlotte Watts Pdf

Our respiratory and immune systems are intrinsically linked to how we relate to the world around us. Engaging with our vitality through the movement we were designed to express equips us with an invaluable ability to support the optimal functioning of our internal systems. This book explains how movement, embodied awareness, and self-compassion can be incorporated into yoga practice to support respiratory and immune health. It delves into how stress, trauma, breath, movement, and posture can impact the quality of these systems and how yoga teachers can integrate a range of practises focussing on movement, meditation, and breath to help improve them. Through an exploration of our boundaries, our breath, and our bodies, this book will help yoga teachers develop a more integrated and nuanced approach to their teaching

Author : Brigitte Wildemann,Patrick Oschmann,Hansotto Reiber
Publisher : Thieme
Page : 624 pages
File Size : 43,7 Mb
Release : 2010-08-11
Category : Medical
ISBN : 9783132579064

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Laboratory Diagnosis in Neurology by Brigitte Wildemann,Patrick Oschmann,Hansotto Reiber Pdf

A practice-oriented reference for the laboratory diagnosis of neurologic diseases Up-to-date, comprehensive, and beautifully illustrated, Laboratory Diagnosis in Neurology presents all the measuring parameters and methods relevant to the analysis of cerebrospinal fluid, serum, and tissues affected by neurologic disease and syndromes. Following an introduction to basic concepts, the book guides clinicians through the methods of CSF analysis, neurochemical examinations, clinical applications of neuroimmunology, microbiology and virology, neurogenetic tests, and evaluation of biopsies. Readers will learn about the equipment and various procedures, and how to effectively differentiate similar methods. In the final section of the book, the authors provide a systematic introduction to the pathophysiology and laboratory findings for specific clinical disorders, indications for particular test methods, and criteria for diagnostic interpretation. Key features: Clear presentation of pearls, pitfalls, and practical tips in blue boxes for at-a-glance review Contributions by neurologists, psychiatrists with experience in laboratory analysis, clinical chemists, and neurochemists More than 140 high-quality illustrations, mostly in full color, demonstrating common findings Appendix with basic rules for interpreting disease-specific patterns, recommendations for quality control, and a list of the most important reference values An indispensable tool for neurologists, laboratory physicians, and pathologists, this book is also a valuable reference for neurosurgeons, internists, and psychiatrists.

Author : Brisa S. Fernandes,Andre F. Carvalho,Stefan Borgwardt,Johann Steiner
Publisher : Frontiers Media SA
Page : 237 pages
File Size : 44,5 Mb
Release : 2020-04-24
Category : Electronic
ISBN : 9782889636617

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Back to the Future: On the Road Towards Precision Psychiatry by Brisa S. Fernandes,Andre F. Carvalho,Stefan Borgwardt,Johann Steiner Pdf

Author : Katherine J. Aitchison,Robin M. Murray,Patrick J. Power,Eva M. Tsapakis
Publisher : CRC Press
Page : 152 pages
File Size : 40,5 Mb
Release : 2022-03-26
Category : Medical
ISBN : 9780429524141

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First Episode Psychosis by Katherine J. Aitchison,Robin M. Murray,Patrick J. Power,Eva M. Tsapakis Pdf

The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management. This is an authoritative text written by a team of highly respected authors for psychiatrists, neurologists, primary care practitioners and health care professional working in psychiatry. Drawing from their experience, the presentation and assessment of the first psychotic episode are discussed, details regarding antipsychotic drugs and their appropriate use are reviewed and psychosocial approaches are examined. The resulting book offers a concise and valuable guide to those wishing to review the latest proposals for the treatment of first-episode psychosis supported by up-to-date references, in a single publication.

Author : Anonim
Publisher : Elsevier
Page : 568 pages
File Size : 48,9 Mb
Release : 2016-03-11
Category : Science
ISBN : 9780444634467

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Autoimmune Neurology by Anonim Pdf

Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Author : I. Berczi,Judith Szélenyi
Publisher : Springer Science & Business Media
Page : 373 pages
File Size : 43,7 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781475791044

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Advances in Psychoneuroimmunology by I. Berczi,Judith Szélenyi Pdf

Proceedings of the Third Hans Selye Symposium on Neuroendocrinology and Stress held in Budapest, Hungary, August 17-21, 1992.

Author : Donald L. Schomer,Fernando Lopes da Silva
Publisher : Lippincott Williams & Wilkins
Page : 1308 pages
File Size : 42,7 Mb
Release : 2012-10-18
Category : Medical
ISBN : 9781451153156

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Niedermeyer's Electroencephalography by Donald L. Schomer,Fernando Lopes da Silva Pdf

The leading reference on electroencephalography since 1982, Niedermeyer's Electroencephalography is now in its thoroughly updated Sixth Edition. An international group of experts provides comprehensive coverage of the neurophysiologic and technical aspects of EEG, evoked potentials, and magnetoencephalography, as well as the clinical applications of these studies in neonates, infants, children, adults, and older adults. This edition's new lead editor, Donald Schomer, MD, has updated the technical information and added a major new chapter on artifacts. Other highlights include complete coverage of EEG in the intensive care unit and new chapters on integrating other recording devices with EEG; transcranial electrical and magnetic stimulation; EEG/TMS in evaluation of cognitive and mood disorders; and sleep in premature infants, children and adolescents, and the elderly. A companion website includes fully searchable text and image bank.

Author : Jorge H. Daruna
Publisher : Academic Press
Page : 336 pages
File Size : 41,9 Mb
Release : 2012-02-24
Category : Medical
ISBN : 9780123820495

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Introduction to Psychoneuroimmunology by Jorge H. Daruna Pdf

Health is maintained by the coordinated operation of all the biological systems that make up the individual. The Introduction to Psychoneuroimmunology, Second Edition, presents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader. Single authored for consistency of breadth and depth, with no redundancy of coverage between chapters Covers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others Expanded use of figures, tables, and text boxes

Author : Tracey A. Cho,Shamik Bhattacharyya,Simon Helfgott
Publisher : Springer
Page : 293 pages
File Size : 44,8 Mb
Release : 2019-06-29
Category : Medical
ISBN : 9783030169282

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Neurorheumatology by Tracey A. Cho,Shamik Bhattacharyya,Simon Helfgott Pdf

This detailed, practical textbook focuses on immune mediated disorders of the nervous system with particular focus on systemic autoimmune disorders. Divided into three sections, the first discusses the neuroanatomical and pathophysiologic basis of immune mediated disorders of the nervous system. Following this are 25 chapters devoted to individual clinical conditions. To conclude, the final section explains what is known about the mechanisms of immunomodulatory treatments and practical points about monitoring patients on these treatments. Neurorheumatology: A Comprehensive Guide to Immune Mediated Disorders of the Nervous System bridges the gaps among different branches of medicine and is an indispensable resource for rheumatologists and neurologists looking to develop a firm understanding of these dynamic disorders

Author : Rudolf N. Cardinal,Edward T. Bullmore
Publisher : Cambridge University Press
Page : 402 pages
File Size : 53,5 Mb
Release : 2011-03-31
Category : Medical
ISBN : 9781139497909

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The Diagnosis of Psychosis by Rudolf N. Cardinal,Edward T. Bullmore Pdf

Psychosis has many causes. Psychiatrists typically receive the most thorough training in its diagnosis, but the diagnosis of psychosis secondary to nonpsychiatric conditions is not often emphasized. An understanding of the underlying cause of psychosis is important for effective management. The Diagnosis of Psychosis bridges the gap between psychiatry and medicine, providing a comprehensive review of primary and secondary causes of psychosis. It covers both common and rare causes in a clinically focused guide. Useful both for teaching and reference, the text covers physical and mental state examination, describes key investigations, and summarizes the non-psychiatric features of medical conditions causing psychosis. Particularly relevant for psychiatrists and trainees in psychiatry, this volume will also assist neurologists and general physicians who encounter psychosis in their practice.

Author : Eelco F.M. Wijdicks
Publisher : Oxford University Press
Page : 688 pages
File Size : 45,7 Mb
Release : 2014-04-28
Category : Medical
ISBN : 9780199331239

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The Comatose Patient by Eelco F.M. Wijdicks Pdf

The Comatose Patient, Second Edition, is a critical historical overview of the concepts of consciousness and unconsciousness, covering all aspects of coma within 100 detailed case vignettes. This comprehensive text includes principles of neurologic examination of comatose patients as well as instruction of the FOUR Score coma scale, and also discusses landmark legal cases and ethical problems. As the Chair of Division of Critical Care Neurology at Mayo Clinic, Dr. Wijdicks uses his extensive knowledge to discuss a new practical multistep approach to the diagnosis of the comatose patient. Additionally, this edition includes extensive coverage of the interpretation of neuroimaging and its role in daily practice and decision making, as well as management in the emergency room and ICU. Dr. Wijdicks details long-term supportive care and an appropriate approach to communication with family members about end-of-life decision making. In addition, video clips on neurologic examination and neurologic manifestations seen in comatose patients can be found here: http://oxfordmedicine.com/comatosepatient2e. All video recordings from the first edition have been reformatted and remastered for optimal use, and several more video clips of patients have also been included.

Author : Eduardo E. Benarroch
Publisher : Oxford University Press
Page : 512 pages
File Size : 44,8 Mb
Release : 2014-04-03
Category : Medical
ISBN : 9780199920204

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Autonomic Neurology by Eduardo E. Benarroch Pdf

The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.