Recent Development Of Electrospinning For Drug Delivery

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Recent Development of Electrospinning for Drug Delivery

Author : Romána Zelkó,Dimitrios A. Lamprou,István Sebe
Publisher : MDPI
Page : 206 pages
File Size : 46,8 Mb
Release : 2020-03-27
Category : Medical
ISBN : 9783039281404

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Recent Development of Electrospinning for Drug Delivery by Romána Zelkó,Dimitrios A. Lamprou,István Sebe Pdf

Several promising techniques have been developed to overcome the poor solubility and/or membrane permeability properties of new drug candidates, including different fiber formation methods. Electrospinning is one of the most commonly used spinning techniques for fiber formation, induced by the high voltage applied to the drug-loaded solution. With modifying the characteristics of the solution and the spinning parameters, the functionality-related properties of the formulated fibers can be finely tuned. The fiber properties (i.e., high specific surface area, porosity, and the possibility of controlling the crystalline–amorphous phase transitions of the loaded drugs) enable the improved rate and extent of solubility, causing a rapid onset of absorption. However, the enhanced molecular mobility of the amorphous drugs embedded into the fibers is also responsible for their physical–chemical instability. This Special Issue will address new developments in the area of electrospun nanofibers for drug delivery and wound healing applications, covering recent advantages and future directions in electrospun fiber formulations and scalability. Moreover, it serves to highlight and capture the contemporary progress in electrospinning techniques, with particular attention to the industrial feasibility of developing pharmaceutical dosage forms. All aspects of small molecule or biologics-loaded fibrous dosage forms, focusing on the processability, structures and functions, and stability issues, are included.

Recent Development of Electrospinning for Drug Delivery

Author : Romána Zelkó,Dimitrios A. Lamprou,István Sebe
Publisher : Unknown
Page : 206 pages
File Size : 50,5 Mb
Release : 2020
Category : Medicine (General)
ISBN : 3039281410

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Recent Development of Electrospinning for Drug Delivery by Romána Zelkó,Dimitrios A. Lamprou,István Sebe Pdf

Several promising techniques have been developed to overcome the poor solubility and/or membrane permeability properties of new drug candidates, including different fiber formation methods. Electrospinning is one of the most commonly used spinning techniques for fiber formation, induced by the high voltage applied to the drug-loaded solution. With modifying the characteristics of the solution and the spinning parameters, the functionality-related properties of the formulated fibers can be finely tuned. The fiber properties (i.e., high specific surface area, porosity, and the possibility of controlling the crystalline-amorphous phase transitions of the loaded drugs) enable the improved rate and extent of solubility, causing a rapid onset of absorption. However, the enhanced molecular mobility of the amorphous drugs embedded into the fibers is also responsible for their physical-chemical instability. This Special Issue will address new developments in the area of electrospun nanofibers for drug delivery and wound healing applications, covering recent advantages and future directions in electrospun fiber formulations and scalability. Moreover, it serves to highlight and capture the contemporary progress in electrospinning techniques, with particular attention to the industrial feasibility of developing pharmaceutical dosage forms. All aspects of small molecule or biologics-loaded fibrous dosage forms, focusing on the processability, structures and functions, and stability issues, are included.

Electrospun Nanofibers

Author : Mehdi Afshari
Publisher : Woodhead Publishing
Page : 648 pages
File Size : 40,6 Mb
Release : 2016-09-13
Category : Technology & Engineering
ISBN : 9780081009116

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Electrospun Nanofibers by Mehdi Afshari Pdf

Electrospun Nanofibers covers advances in the electrospinning process including characterization, testing and modeling of electrospun nanofibers, and electrospinning for particular fiber types and applications. Electrospun Nanofibers offers systematic and comprehensive coverage for academic researchers, industry professionals, and postgraduate students working in the field of fiber science. Electrospinning is the most commercially successful process for the production of nanofibers and rising demand is driving research and development in this field. Rapid progress is being made both in terms of the electrospinning process and in the production of nanofibers with superior chemical and physical properties. Electrospinning is becoming more efficient and more specialized in order to produce particular fiber types such as bicomponent and composite fibers, patterned and 3D nanofibers, carbon nanofibers and nanotubes, and nanofibers derived from chitosan. Provides systematic and comprehensive coverage of the manufacture, properties, and applications of nanofibers Covers recent developments in nanofibers materials including electrospinning of bicomponent, chitosan, carbon, and conductive fibers Brings together expertise from academia and industry to provide comprehensive, up-to-date information on nanofiber research and development Offers systematic and comprehensive coverage for academic researchers, industry professionals, and postgraduate students working in the field of fiber science

Nanofibres in Drug Delivery

Author : Gareth R. Williams ,Bahijja T. Raimi-Abraham,C. J. Luo
Publisher : UCL Press
Page : 242 pages
File Size : 51,5 Mb
Release : 2018-09-17
Category : Medical
ISBN : 9781787350182

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Nanofibres in Drug Delivery by Gareth R. Williams ,Bahijja T. Raimi-Abraham,C. J. Luo Pdf

In recent years there has been an explosion of interest in the production of nanoscale fibres for drug delivery and tissue engineering. Nanofibres in Drug Delivery aims to outline to new researchers in the field the utility of nanofibres in drug delivery, and to explain to them how to prepare fibres in the laboratory. The book begins with a brief discussion of the main concepts in pharmaceutical science. The authors then introduce the key techniques that can be used for fibre production and explain briefly the theory behind them. They discuss the experimental implementation of fibre production, starting with the simplest possible set-up and then moving on to consider more complex arrangements. As they do so, they offer advice from their own experience of fibre production, and use examples from current literature to show how each particular type of fibre can be applied to drug delivery. They also consider how fibre production could be moved beyond the research laboratory into industry, discussing regulatory and scale-up aspects.

Electrospinning

Author : Sajjad Haider,Adnan Haider
Publisher : BoD – Books on Demand
Page : 168 pages
File Size : 51,6 Mb
Release : 2016-12-21
Category : Science
ISBN : 9789535128212

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Electrospinning by Sajjad Haider,Adnan Haider Pdf

This is a timely, an informative, an interesting, and a well-managed book. The book not only offers an in-depth review of the current status of the knowledge of electrospinning and its biomedical applications but also discusses the emerging ideas and features, both from the East and West, with a focus on the needless electrospinning for the production of uniform fibers. The book is equally helpful to the experts of this field, who wish to enhance their understanding of the emerging technologies, and to the new comers, who can use this book as a reference.

Nanofibres in Drug Delivery

Author : Gareth R. Williams,Bahijja T. Raimi-Abraham,C. J. Luo
Publisher : UCL Press
Page : 244 pages
File Size : 45,7 Mb
Release : 2018-09-17
Category : Medical
ISBN : 9781787350236

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Nanofibres in Drug Delivery by Gareth R. Williams,Bahijja T. Raimi-Abraham,C. J. Luo Pdf

In recent years there has been an explosion of interest in the production of nanoscale fibres for drug delivery and tissue engineering. Nanofibres in Drug Delivery aims to outline to new researchers in the field the utility of nanofibres in drug delivery, and to explain to them how to prepare fibres in the laboratory. The book begins with a brief discussion of the main concepts in pharmaceutical science. The authors then introduce the key techniques that can be used for fibre production and explain briefly the theory behind them. They discuss the experimental implementation of fibre production, starting with the simplest possible set-up and then moving on to consider more complex arrangements. As they do so, they offer advice from their own experience of fibre production, and use examples from current literature to show how each particular type of fibre can be applied to drug delivery. They also consider how fibre production could be moved beyond the research laboratory into industry, discussing regulatory and scale-up aspects.

Innovative Approaches for Nanobiotechnology in Healthcare Systems

Author : Amna, Touseef,Hassan, M. Shamshi
Publisher : IGI Global
Page : 424 pages
File Size : 46,8 Mb
Release : 2021-09-17
Category : Technology & Engineering
ISBN : 9781799882527

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Innovative Approaches for Nanobiotechnology in Healthcare Systems by Amna, Touseef,Hassan, M. Shamshi Pdf

Innovative and fusion technologies have shown an incredible ability to improve various aspects of society, such as healthcare systems. Nanobiotechnology is one such technology that is being applied to medical equipment and treatment approaches. Many pharmaceutical and medical companies have begun to count on medical nanotechnology due to its abundant applications and practical uses. Innovative Approaches for Nanobiotechnology in Healthcare Systems is a pivotal reference source that provides insights into a comprehensive collection of novel techniques used for the development of safe drugs using the available resources for diverse deadly diseases. This book discusses the various platforms of nanobiotechnology that are utilized in various fields. It is expected that bionanosytems will play a crucial role in the treatment of human diseases and the improvement of existing healthcare systems. This book is ideal for scientists, biotechnologists, microbiologists, medical professionals, entrepreneurs, policymakers, researchers, academicians, and students.

Electrospun Nanofibers

Author : Ashok Vaseashta,Nimet Bölgen
Publisher : Springer Nature
Page : 769 pages
File Size : 44,6 Mb
Release : 2022-07-14
Category : Technology & Engineering
ISBN : 9783030999582

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Electrospun Nanofibers by Ashok Vaseashta,Nimet Bölgen Pdf

This book presents the development of electrospun materials, fundamental principles of electrospinning process, controlling parameters, electrospinning strategies, and electrospun nanofibrous structures with specific properties for applications in tissue engineering and regenerative medicine, textile, water treatment, sensor, and energy fields. This book can broadly be divided into three parts: the first comprises basic principles of electrospinning process, general requirements of electrospun materials and advancement in electrospinning technology, the second part describes the applications of electrospun materials in different fields and future prospects, while the third part describes applications that can be used in advanced manufacturing based on conjoining electrospinning and 3D printing. Electrospinning is the most successful process for producing functional nanofibers and nanofibrous membranes with superior chemical and physical properties. The unique properties of electrospun materials including high surface to volume ratio, flexibility, high mechanical strength, high porosity, and adjustable nanofiber and pore size distribution make them potential candidates in a wide range of applications in biomedical and engineering areas. Electrospinning is becoming more efficient and more specialized in order to produce particular fiber types with tunable diameter and morphology, tunable characteristics, having specific patterns and 3D structures. With a strong focus on fundamental materials science and engineering, this book provides systematic and comprehensive coverage of the recent developments and novel perspectives of electrospun materials. This comprehensive book includes chapters that discuss the latest and emerging applications of nanofiber technology in various fields, specifically in areas such as wearable textile, biomedical applications, energy generation and storage, water treatment and environmental remediation, and sensors such as biomarkers in healthcare and biomedical engineering. Despite all these advancements, there are still challenges to be addressed and overcome for nanofiber technology to move towards maturation.

Electrospinning and Electrospraying

Author : Sajjad Haider,Adnan Haider
Publisher : BoD – Books on Demand
Page : 122 pages
File Size : 40,6 Mb
Release : 2019-12-11
Category : Science
ISBN : 9781789847000

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Electrospinning and Electrospraying by Sajjad Haider,Adnan Haider Pdf

This book focuses on the recent advancements in the process parameters, research, and applications of electrospinning and electrospraying. The first chapter introduces the techniques and the effect of the parameters on the morphology of the nanofiber and nanoparticles and then the subsequent chapters focus on the applications of these techniques in different areas. This book will attract a broad audience including postgraduate students and industrial and academic investigators in sciences and engineering who wish to enhance their understanding of the emerging technologies and use this book as reference.

Nanopharmaceutical Advanced Delivery Systems

Author : Vivek Dave,Nikita Gupta,Srija Sur
Publisher : John Wiley & Sons
Page : 467 pages
File Size : 46,7 Mb
Release : 2020-12-29
Category : Computers
ISBN : 9781119711681

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Nanopharmaceutical Advanced Delivery Systems by Vivek Dave,Nikita Gupta,Srija Sur Pdf

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Electrospun Materials and Their Allied Applications

Author : Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 42,7 Mb
Release : 2020-05-27
Category : Technology & Engineering
ISBN : 9781119654865

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Electrospun Materials and Their Allied Applications by Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri Pdf

The aim of this book is to explore the history, fundamentals, manufacturing processes, optimization parameters, and applications of electrospun materials. The book includes various types of electrospun materials such as antimicrobial, smart, bioinspired systems. It focuses on the many application areas for electrospun materials such as energy storage and harvesting, catalysis, biomedical including gene delivery and tissue engineering, separation, adsorption and water treatment technologies, packaging. The book emphasizes the enhanced sustainable properties of electrospun materials, with the challenges and future developments being discussed in detail. The chapters are written by top-class researchers and experts from throughout the world.

Emerging Drug Delivery and Biomedical Engineering Technologies

Author : Dimitrios Lamprou
Publisher : CRC Press
Page : 535 pages
File Size : 53,9 Mb
Release : 2023-04-05
Category : Medical
ISBN : 9781000857337

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Emerging Drug Delivery and Biomedical Engineering Technologies by Dimitrios Lamprou Pdf

This book details the advances in drug discovery and delivery and the present need for emerging technologies. Throughout the text new micro and nanofabrication techniques are described, including methods such as electrohydrodynamic processes, additive manufacturing, and microfluidics, which have the potential to produce drug delivery systems that were not possible a few years ago. This book is of great use to both entry-level and experienced researchers in the field of emerging technologies for the manufacturing of drug delivery devices. Features: Describes technologies that are significantly enhancing the delivery of drugs and biologics Presents new data on mobile and wearable point-of-care testing systems Features hot topics such as electrospinning, 3D printing and micro-needles Focuses on additive manufacturing (AM) which can be used to provide customized treatment for patients Will appeal to experienced researchers and those considering entering the field of emerging technologies for the manufacturing of drug delivery devises

Synthesis and Applications of Electrospun Nanofibers

Author : Ramazan Asmatulu,Waseem S. Khan
Publisher : Elsevier
Page : 306 pages
File Size : 51,8 Mb
Release : 2018-10-12
Category : Science
ISBN : 9780128139158

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Synthesis and Applications of Electrospun Nanofibers by Ramazan Asmatulu,Waseem S. Khan Pdf

Synthesis and Applications of Electrospun Nanofibers examines processing techniques for nanofibers and their applications in a variety of industry sectors, including energy, agriculture and biomedicine. The book gives readers a thorough understanding of both electrospinning and interfacial polymerization techniques for their production. In addition, the book explore the use of nanofibers in a variety of industry sectors, with particular attention given to nanofibers in medicine, such as in drug and gene delivery, artificial blood vessels, artificial organs and medical facemasks, and in energy and environmental applications. Specific topics of note include fuel cells, lithium ion batteries, solar cells, supercapacitors, energy storage materials, sensors, filtration materials, protective clothing, catalysis and electromagnetic shielding. This book will serve as an important reference resource for materials scientists, engineers and biomedical scientists who want to learn more on the uses of nanofibers. Describes a variety of techniques for producing nanofibers Shows how nanofibers are used in a range of industrial sectors, including illustrative case studies Discusses the pros and cons of using different fabrication techniques to produce nanofibers

Electrospinning for Advanced Biomedical Applications and Therapies

Author : Nuno M Neves
Publisher : Smithers Rapra
Page : 338 pages
File Size : 46,5 Mb
Release : 2012-08-30
Category : Technology & Engineering
ISBN : 9781847356024

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Electrospinning for Advanced Biomedical Applications and Therapies by Nuno M Neves Pdf

The main focus of this book is on the development of electrospun membranes for advanced biomedical technologies including tissue engineering and drug delivery devices.Serving as a reference book for the beginner this book also provides an in-depth analysis of the challenges to be overcome in the future. Each section of the book covers not only the developments in the various fields of application of the electrospun meshes, but also the advances required for the successful development of new and high-end biomedical applications.Important areas tackled include:Biomedical applications of the technologySpecific aspects of equipments and materialsSurface characterization and functionalizationIn vitro testing with electrospun meshes. In all of these areas the main achievements, challenges ahead and expert opinions are given, making this book highly unusual in the level of detail covered.

Nanomaterials

Author : Igor Linkov,Jeffery A. Steevens
Publisher : Springer Science & Business Media
Page : 459 pages
File Size : 47,6 Mb
Release : 2008-12-26
Category : Technology & Engineering
ISBN : 9781402094910

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Nanomaterials by Igor Linkov,Jeffery A. Steevens Pdf

Many potential questions regarding the risks associated with the development and use of wide-ranging technologies enabled through engineered nanomaterials. For example, with over 600 consumer products available globally, what information exists that describes their risk to human health and the environment? What en- neering or use controls can be deployed to minimize the potential environmental health and safety impacts of nanomaterials throughout the manufacturing and product lifecycles? How can the potential environmental and health benefits of nanotechnology be realized and maximized? The idea for this book was conceived at the NATO Advanced Research Workshop (ARW) on “Nanomaterials: Environmental Risks and Benefits and Emerging Consumer Products. ” This meeting – held in Algarve, Portugal, in April 2008 – started with building a foundation to harmonize risks and benefits associated with nanomaterials to develop risk management approaches and policies. More than 70 experts, from 19 countries, in the fields of risk assessment, decision-analysis, and security discussed the current state-of-knowledge with regard to nanomaterial risk and benefits. The discussion focused on the adequacy of available risk assessment tools to guide nanomaterial applications in industry and risk governance. The workshop had five primary purposes: Describe the potential benefits of nanotechnology enabled commercial products. Identify and describe what is known about environmental and human health risks of nanomaterials and approaches to assess their safety. Assess the suitability of multicriteria decision analysis for reconciling the benefits and risks of nanotechnology.