Research Of Pathogenesis And Novel Therapeutics In Arthritis

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Research of Pathogenesis and Novel Therapeutics in Arthritis

Author : Chih-Hsin Tang
Publisher : MDPI
Page : 366 pages
File Size : 53,8 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9783038970651

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Research of Pathogenesis and Novel Therapeutics in Arthritis by Chih-Hsin Tang Pdf

Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.

Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0

Author : Hih-Hsin Tang
Publisher : Mdpi AG
Page : 0 pages
File Size : 44,6 Mb
Release : 2023-05-24
Category : Electronic
ISBN : 3036575928

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Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0 by Hih-Hsin Tang Pdf

Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features of the disease, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used in the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of heart attack and other cardiovascular problems. It is therefore crucial that we continue to research the pathogenesis of arthritis and seek to discover novel modes of therapy. This book summarizes the themes of the 29 articles published in our Special Issue "Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0". This book details important novel research discoveries that contribute to our current understanding of arthritis.

Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0

Author : Chih-Hsin Tang
Publisher : Unknown
Page : 0 pages
File Size : 40,6 Mb
Release : 2023
Category : Electronic
ISBN : 3036575936

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Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0 by Chih-Hsin Tang Pdf

Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features of the disease, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used in the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of heart attack and other cardiovascular problems. It is therefore crucial that we continue to research the pathogenesis of arthritis and seek to discover novel modes of therapy. This reprint summarizes the themes of the 29 articles published in our Special Issue “Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0”. This reprint details important novel research discoveries that contribute to our current understanding of arthritis.

Research of Pathogenesis and Novel Therapeutics in Arthritis

Author : Chih-Hsin Tang
Publisher : Unknown
Page : 366 pages
File Size : 52,7 Mb
Release : 2019
Category : Medicine (General)
ISBN : 3038970662

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Research of Pathogenesis and Novel Therapeutics in Arthritis by Chih-Hsin Tang Pdf

Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.

Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0

Author : Chih-Hsin Tang
Publisher : Mdpi AG
Page : 0 pages
File Size : 52,5 Mb
Release : 2023-06-30
Category : Electronic
ISBN : 3036580840

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Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0 by Chih-Hsin Tang Pdf

Arthritis has a high prevalence globally and includes over 100 types; the most common types are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features, including monocyte infiltration, inflammation, synovial swelling, pannus formation, stiffness in the joints, and articular cartilage destruction. The exact etiology of arthritis remains unclear, and no cure exists as of yet. Anti-inflammatory drugs (NSAIDs and corticosteroids) are commonly used for the treatment of arthritis. However, these drugs are associated with significant side effects, such as gastric bleeding and an increased risk of a heart attack and other cardiovascular problems. Therefore, it is crucial that we continue to research the pathogenesis of arthritis and novel modes of therapy. This reprint summarizes and discusses the themes of 19 articles published in our Special Issue "Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0". The reprint details important novel research discoveries that contribute to our current understanding of arthritis.

Inflammation and Rheumatic Diseases

Author : Stefan Laufer,Steffen Gay,Kay Brune
Publisher : Georg Thieme Verlag
Page : 154 pages
File Size : 49,5 Mb
Release : 2003
Category : Anti-inflammatory agents
ISBN : 3131330910

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Inflammation and Rheumatic Diseases by Stefan Laufer,Steffen Gay,Kay Brune Pdf

This book is a useful guide for students, physicians in continuing education and practitioners who want to keep abreast of the latest developments in rheumatology. The chapters on the pathogenesis of rheumatoid arthritis and the biochemistry of inflammation present the latest research results in this field and are illustrated by a wealth of charts and tables. There follows practical and critical information on all drug groups that are currently used in the treatment of inflammatory rheumatic diseases and osteoarthritis. (Midwest).

Osteoarthritis

Author : Mohit Kapoor,Nizar N. Mahomed
Publisher : Springer
Page : 278 pages
File Size : 54,9 Mb
Release : 2015-07-20
Category : Medical
ISBN : 9783319195605

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Osteoarthritis by Mohit Kapoor,Nizar N. Mahomed Pdf

This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patient’s phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics.

New Developments in the Pathogenesis of Rheumatoid Arthritis

Author : Lazaros Sakkas
Publisher : BoD – Books on Demand
Page : 166 pages
File Size : 42,7 Mb
Release : 2017-02-22
Category : Medical
ISBN : 9789535129691

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New Developments in the Pathogenesis of Rheumatoid Arthritis by Lazaros Sakkas Pdf

The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-6, and also T cells and B cells, reinforced the pathogenetic role of the respective factors. ACPAs, induced by cigarette smoking and periodontitis in individuals with HLA-DRB1 shared epitope, appear to be autoantigens that initiate the inflammatory immune response in RA. MicroRNAs, part of epigenetic mechanisms, which also include DNA methylation, and histone modification, as well as microbiota, the composition of microbes in body cavities, also appear to influence arthritis and are discussed in this book.

Arthritis Research

Author : Frank H. Columbus
Publisher : Nova Publishers
Page : 250 pages
File Size : 43,9 Mb
Release : 2005
Category : Arthritis
ISBN : 1590339843

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Arthritis Research by Frank H. Columbus Pdf

Arthritis is an inflammatory disease affecting the joints and surrounding tissues. As the disease develops it can cause severe pain and disability. The two most common types of arthritis are osteoarthritis and rheumatoid arthritis. Osteoarthritis (OA) is a painful, degenerative joint disease that often involves the hips, knees, neck, lower back, or the small joints of the hands. Treatment usually includes analgesics, topical creams, or non-steroidal anti-inflammatory medications (known as NSAIDs); appropriate exercises or physical therapy; joint splinting; or joint replacement surgery for seriously damaged larger joints, such as the knee or hip. Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that usually involves the hands, wrists, elbows, shoulders, knees, feet, or ankles. This new book brings together leading research in the field.

Post-Traumatic Arthritis

Author : Steven A. Olson, MD,Farshid Guilak, PhD
Publisher : Springer
Page : 360 pages
File Size : 50,9 Mb
Release : 2015-06-29
Category : Medical
ISBN : 9781489976062

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Post-Traumatic Arthritis by Steven A. Olson, MD,Farshid Guilak, PhD Pdf

Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-articular tissue responses to of joint injury and potential mechanisms of PTA; the current clinical assessment and treatment of common joint injuries leading to PTA; and emerging technologies and treatments for PTA, including biomarkers and stem cell therapies. Taken together, it will be an invaluable resource for orthopedic surgeons, rheumatologists and other joint injury researchers and clinicians.

Bone and Osteoarthritis

Author : Felix Bronner,Mary C. Farach-Carson
Publisher : Springer Science & Business Media
Page : 218 pages
File Size : 53,6 Mb
Release : 2007-09-26
Category : Medical
ISBN : 9781846287015

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Bone and Osteoarthritis by Felix Bronner,Mary C. Farach-Carson Pdf

The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on genetics and on newer viewpoints and approaches, exemplified by the possible effect of subchondral bone on osteoarthritis, gives a wider viewpoint to the reader and may enable novel approaches to solving a clinical problem.

Arthritis

Author : Debasis Bagchi,Hiroyoshi Moriyama,Siba P. Raychaudhuri
Publisher : Unknown
Page : 0 pages
File Size : 47,7 Mb
Release : 2019-10-15
Category : Electronic
ISBN : 0367382873

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Arthritis by Debasis Bagchi,Hiroyoshi Moriyama,Siba P. Raychaudhuri Pdf

An overall analysis of available arthritis treatments, including osteo- and rheumatoid arthritis, this book covers pathophysiology, traditional medicine, alternative therapies, and lifestyle changes. It focuses on treatment regimens, including synthetic drugs, their safety and toxicity; natural and herbal products; healthy foods; and non pharmacologic interventions such as acupuncture and psychosocial management. With numerous tables, figures, and charts, it examines the association of arthritis in obesity, hypertension, and cardiovascular disease and offers extensive research on natural products as well as synthetic drugs such as COX-2 inhibitors.

Oxford Textbook of Rheumatology

Author : Philip Conaghan,Chris Denton,Helen Foster,John Isaacs
Publisher : Oxford University Press
Page : 1553 pages
File Size : 51,8 Mb
Release : 2013-10
Category : Medical
ISBN : 9780199642489

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Oxford Textbook of Rheumatology by Philip Conaghan,Chris Denton,Helen Foster,John Isaacs Pdf

A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.

Mayo Clinic Internal Medicine Board Review Questions and Answers

Author : Robert D. Ficalora
Publisher : Oxford University Press
Page : 164 pages
File Size : 46,8 Mb
Release : 2013-08-15
Category : Medical
ISBN : 9780199985876

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Mayo Clinic Internal Medicine Board Review Questions and Answers by Robert D. Ficalora Pdf

Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013.

Periprosthetic Joint Infection: Practical Management Guide

Author : Parvizi Javad ,Kerr Glenn J,Glynn Aaron,Higuera Carlos A,Hansen Erik N
Publisher : JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
Page : 432 pages
File Size : 42,8 Mb
Release : 2013-12-15
Category : Artificial joints
ISBN : 9789350908259

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Periprosthetic Joint Infection: Practical Management Guide by Parvizi Javad ,Kerr Glenn J,Glynn Aaron,Higuera Carlos A,Hansen Erik N Pdf

This book Periprosthetic Joint Infection is a portable guide to the practical management of surgical site infections following orthopedic procedures. It designed to help answer clinician's questions regarding the prevention and treatment of periprosthetic infections. It organized for rapid review, featuring evidence reviews, pitfalls, Rothman Institute Current Practices and Controversies. The guide is being included in the course materials for the 29th Annual Current Concepts in Joint Replacement® (CCJR) meeting thanks to a generous educational grant from 3M Health Care.