Restoring Functional Behaviors After Traumatic Peripheral Nerve Injuries

Author : George Davis Bittner,Jared Bushman,Jaimie Shores,Joseph Alderete,Dale Sengelaub
Publisher : Frontiers Media SA
Page : 142 pages
File Size : 47,8 Mb
Release : 2024-02-20
Category : Science
ISBN : 9782832544785

Get Book

Restoring Functional Behaviors After Traumatic Peripheral Nerve Injuries by George Davis Bittner,Jared Bushman,Jaimie Shores,Joseph Alderete,Dale Sengelaub Pdf

Peripheral nerve injuries (PNIs) by trauma are the most common neuronal injury in civilian and military populations and significantly burden health care systems. Mammals (including humans) with PNIs experience: (1) immediate loss of sensory and motor functions mediated by the denervated target tissues; (2) rapid (3-7d) Wallerian Degeneration (WD) of severed distal axonal segments; and, (3) slow (~1mm/day) regeneration by naturally occurring axonal outgrowths from surviving, severed proximal stumps that produce poor (if any) functional recovery because of slow axonal regeneration for long distances and lack of axonal guidance. Denervated muscle fibers and sensory organs often atrophy before any re-innervation can occur.

Author : Giovanna Gambarotta,Kirsten Haastert-Talini,Esther Udina,Stefania Raimondo,James Phillips
Publisher : Frontiers Media SA
Page : 302 pages
File Size : 44,9 Mb
Release : 2019-12-24
Category : Electronic
ISBN : 9782889632688

Get Book

Peripheral Nerve Regeneration by Giovanna Gambarotta,Kirsten Haastert-Talini,Esther Udina,Stefania Raimondo,James Phillips Pdf

Author : Seyed Mansoor Rayegani
Publisher : BoD – Books on Demand
Page : 292 pages
File Size : 52,6 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9789535104070

Get Book

Basic Principles of Peripheral Nerve Disorders by Seyed Mansoor Rayegani Pdf

Peripheral nerve disorders are comprising one of the major clinical topics in neuromusculoskeletal disorders. Sharp nerve injuries, chronic entrapment syndromes, and peripheral neuropathic processes can be classified in this common medical topic. Different aspects of these disorders including anatomy, physiology, pathophysiology, injury mechanisms, and different diagnostic and management methods need to be addressed when discussing this topic. The goal of preparing this book was to gather such pertinent chapters to cover these aspects.

Author : Dr Thomas Wilson,Dr Lynda J-S Yang
Publisher : Oxford University Press
Page : 320 pages
File Size : 48,9 Mb
Release : 2018-10-02
Category : Medical
ISBN : 9780190617141

Get Book

Peripheral Nerve Surgery by Dr Thomas Wilson,Dr Lynda J-S Yang Pdf

Part of the Neurosurgery by Example series, this volume on peripheral nerve disorders presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases are divided into four distinct areas of peripheral nerve pathology: entrapment and inflammatory neuropathies, peripheral nerve pain syndromes, peripheral nerve tumors, and peripheral nerve trauma. Each chapter also contains 'pivot points' that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Peripheral Nerve Surgery is appropriate for neurosurgeons who wish to learn more about this subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

Author : William M. Reichert
Publisher : CRC Press
Page : 296 pages
File Size : 43,9 Mb
Release : 2007-12-17
Category : Science
ISBN : 1420009303

Get Book

Indwelling Neural Implants by William M. Reichert Pdf

Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections · Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body. · Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing. · Part three presents both in vitro and in vivo approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an in vivo model is used to assess molecular transport in brain tissue surrounding the implant. · The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair. This seminal work provides researchers with an up-to-date account of the progress in the field that they can build upon to bring us closer to realizing the full value of neural implants in combating otherwise intractable human health problems.

Author : Jianguo Cheng
Publisher : Oxford University Press
Page : 337 pages
File Size : 48,9 Mb
Release : 2019-01-21
Category : Medical
ISBN : 9780190298357

Get Book

Neuropathic Pain by Jianguo Cheng Pdf

Neuropathic pain is one of the most common, most debilitating, most costly, and most difficult to treat categories of chronic pain conditions that are characterized by a lesion or disease of the somatosensory nervous system. Managing neuropathic pain is challenging and requires skillful assessment and comprehensive and integrated treatment strategies that are mechanism-guided, evidence-based, and individualized. However, these critical and integral elements are very fragmented in the current literature. The mechanistic understanding of neuropathic pain is typically found in basic research articles. Clinical research evidence is presented in forms of clinical trials with emphasis on minimizing biases such as those from patient selection and assessment. Individualized considerations for each patient are usually presented in case reports and problem-based learning discussions. This book overcomes these barriers and integrates all the critical elements around individual patient care into a coherent management strategy that is practical and applicable to daily clinical practice. Rather than compiling what have been published in the literature, this work emphasizes on identifying and highlighting the key points or findings that guide decision-making in clinical practice. It integrates the key points around a typical case scenario that not only represents the core of the diagnostic and therapeutic processes but also allows introduction and differentiation of painful conditions that bare similarities with the case in hand. The overarching goal is to improve clinical outcomes through better understanding of the mechanisms, more accurate diagnosis, and wiser and more comprehensive treatment strategies.

Author : Hiroaki Naritomi,D. W. Krieger
Publisher : Karger Medical and Scientific Publishers
Page : 162 pages
File Size : 40,6 Mb
Release : 2013
Category : Medical
ISBN : 9783318023084

Get Book

Clinical Recovery from CNS Damage by Hiroaki Naritomi,D. W. Krieger Pdf

A compilation of innovative findings and new directions in neurological recovery After decades of focusing on how to alleviate and prevent recurrence of acute CNS injuries, the emphasis has finally shifted towards repairing such devastating events and rehabilitation. This development has been made possible by substantial progress in understanding the scientific underpinnings of recovery as well as by novel diagnostic tools, and most importantly, by emerging therapies awaiting clinical trials. In this publication, several international experts introduce novel areas of neurological reorganization and repair following CNS damage. Principles and methods to monitor and augment neuroplasticity are explored in depth and supplemented by a critical appraisal of neurological repair mechanisms and possibilities to curtail disability using computer or robotic interfaces. Rather than providing a textbook approach of CNS restoration, the editors selected topics where progress is most imminent in this labyrinthine domain of medicine. Moreover, the varied background and origins of the contributors lend this book a truly global perspective on the current state of affairs in neurological recovery.

Author : National Research Council,Division on Earth and Life Studies,Institute of Medicine,Commission on Life Sciences,Committee on Trauma Research
Publisher : National Academies Press
Page : 175 pages
File Size : 54,5 Mb
Release : 1985-01-01
Category : Medical
ISBN : 9780309035453

Get Book

Injury in America by National Research Council,Division on Earth and Life Studies,Institute of Medicine,Commission on Life Sciences,Committee on Trauma Research Pdf

"Injury is a public health problem whose toll is unacceptable," claims this book from the Committee on Trauma Research. Although injuries kill more Americans from 1 to 34 years old than all diseases combined, little is spent on prevention and treatment research. In addition, between $75 billion and $100 billion each year is spent on injury-related health costs. Not only does the book provide a comprehensive survey of what is known about injuries, it suggests there is a vast need to know more. Injury in America traces findings on the epidemiology of injuries, prevention of injuries, injury biomechanics and the prevention of impact injury, treatment, rehabilitation, and administration of injury research.

Author : Bo He,Ji-Fan Hu,Zhaowei Zhu
Publisher : Frontiers Media SA
Page : 148 pages
File Size : 41,6 Mb
Release : 2023-02-08
Category : Science
ISBN : 9782832513996

Get Book

The function of Schwann cells in peripheral nervous system by Bo He,Ji-Fan Hu,Zhaowei Zhu Pdf

Author : Jörg Bahm
Publisher : BoD – Books on Demand
Page : 178 pages
File Size : 50,8 Mb
Release : 2022-01-26
Category : Medical
ISBN : 9781839696862

Get Book

Brachial Plexus Injury by Jörg Bahm Pdf

In this book, specialists from different countries and continents share their knowledge and experience in brachial plexus surgery. It discusses the different types of brachial plexus injury and advances in surgical treatments.

Author : Augustus D Mazzocca,Adam Lindsay
Publisher : Elsevier Health Sciences
Page : 400 pages
File Size : 47,9 Mb
Release : 2018-11-27
Category : Medical
ISBN : 9780323551410

Get Book

Biologics in Orthopaedic Surgery by Augustus D Mazzocca,Adam Lindsay Pdf

Designed with the practicing clinician in mind, Biologics in Orthopaedic Surgery provides a succinct, easy-to-digest overview of the integration of biologics (platelet-rich-plasma [PRP], bone marrow aspirate [BMA], and stem cells) into today’s orthopaedic practice. Covering relevant basic science as well as clinical applications, this concise reference takes a head-to-toe approach to the emerging role of orthobiologics for specific conditions and procedures, in addition to future directions for implementation.

Author : Mahmut Nedim Doral,Jon Karlsson
Publisher : Springer Nature
Page : 3295 pages
File Size : 40,7 Mb
Release : 2015-06-29
Category : Medical
ISBN : 9783642365690

Get Book

Sports Injuries by Mahmut Nedim Doral,Jon Karlsson Pdf

Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.

Author : Kwok Fai So,Xiao-Ming Xu
Publisher : Academic Press
Page : 444 pages
File Size : 49,8 Mb
Release : 2015-02-03
Category : Science
ISBN : 9780128018347

Get Book

Neural Regeneration by Kwok Fai So,Xiao-Ming Xu Pdf

Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including: Neural regeneration in lower vertebrates Neural regeneration in the peripheral nervous system Neural regeneration in the central nervous system Transplantation-mediated neural regeneration Clinical and translational research on neural regeneration The contributors to this book are experts in their fields and work at distinguished institutions in the United States, Canada, Australia, and China. Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapidly growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate the most optimal regenerative strategies to treatments of human nervous system injuries. This valuable reference book is useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research. Provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration Highly translational and clinically-relevance International authors who are leaders in their respective fields Vivid art work making the chapters easily understood

Author : Anonim
Publisher : Unknown
Page : 912 pages
File Size : 54,9 Mb
Release : 1988
Category : Medicine
ISBN : IND:30000090515457

Get Book

Biomedical Index to PHS-supported Research by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 1064 pages
File Size : 42,5 Mb
Release : 1992
Category : Medicine
ISBN : MINN:31951P00216728F

Get Book

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H by Anonim Pdf