Retinoids In Dermatology

Author : Ayse Serap Karadag,Berna Aksoy,Lawrence Charles Parish
Publisher : CRC Press
Page : 508 pages
File Size : 50,8 Mb
Release : 2019-10-28
Category : Medical
ISBN : 9780429852619

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Retinoids in Dermatology by Ayse Serap Karadag,Berna Aksoy,Lawrence Charles Parish Pdf

Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.

Author : Anders Vahlquist,Madeleine Duvic
Publisher : CRC Press
Page : 390 pages
File Size : 53,9 Mb
Release : 2007-06-20
Category : Medical
ISBN : 9781420021189

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Retinoids and Carotenoids in Dermatology by Anders Vahlquist,Madeleine Duvic Pdf

This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of

Author : Zoe Diana Draelos
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 41,7 Mb
Release : 2015-10-08
Category : Medical
ISBN : 9781118655481

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Cosmetic Dermatology by Zoe Diana Draelos Pdf

Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

Author : Stephen E. Wolverton,Jashin . Wu
Publisher : Elsevier Health Sciences
Page : 858 pages
File Size : 54,8 Mb
Release : 2019-12-14
Category : Medical
ISBN : 9780323612128

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Comprehensive Dermatologic Drug Therapy by Stephen E. Wolverton,Jashin . Wu Pdf

Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you’re likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You’ll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. Covers the best uses for new biologic therapeutics. Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a highly detailed, disease-specific index, as well as purchase information for major drugs. Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book.

Author : C.E. Orfanos,O. Braun-Falco,E.M. Farber,C. Grupper,M.K. Polano,R. Schuppli
Publisher : Springer Science & Business Media
Page : 500 pages
File Size : 41,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642680236

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Retinoids by C.E. Orfanos,O. Braun-Falco,E.M. Farber,C. Grupper,M.K. Polano,R. Schuppli Pdf

With the aromatic retinoic acid analog Tigason oral and intravenous pharmacokinetic studies have been performed in 5 normal volunteers. Simultaneous fitting of single i. v. and oral data to a three-compartment model assuming first-order absorption was possible. Using Nonlin parameter estimates of the single-dose data, one is able to predict the decline in plasma levels of parent drug following cessation of a 10 days multiple dosing regimen up to 24 hours. The model is however unable to predict a phase of prolonged elimination observed beyond 24 hours. Moreover in 5 patients, who underwent chronic therapy (8-15 months), substantial plasma levels of both unchanged drug and main metabolite (corre sponding carboxylic acid) were observed up to 140 days after cessation of the therapy. An apparent half-life of elimination of 80-100 days can be calculated. The drug appears to be stored at some yet unknown storage site. Investigation of metabolism of Tigason in rats and humans revealed 19 different bio transformation products thus far, most of them appearing in the urine in low amounts (20010 of dose). A few of them (mainly the acid Ro 10-1670) after conjugation to glucuronic acid are excreted in the bile in high amounts (60-80% of dose). No drug appeared unchanged in the excreta after i. v. administration to rats. References 1. Bollag W (1971) Effects of vitamin A acid (NSC-122758) on transplantable and chemically-induced tumors. Cancer Chemother Rep 55:53-58 2.

Author : Uwe Reichert,B. Schroot
Publisher : Unknown
Page : 308 pages
File Size : 45,7 Mb
Release : 1989
Category : Medical
ISBN : UOM:39015072263042

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Pharmacology of Retinoids in the Skin by Uwe Reichert,B. Schroot Pdf

Author : W.J. Cunliffe,A.J. Miller
Publisher : Springer Science & Business Media
Page : 386 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401163491

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Retinoid Therapy by W.J. Cunliffe,A.J. Miller Pdf

The impact of the retinoids in clinical practice has primarily been in dermatology. When Dr Werner Bollag began his basic research and screening programme in the early 1960's, the expectation was that the retinoids would have a major impact on oncology. However, the laboratory and clinical experiences of Bollag and his colleagues in Switzerland, Stuttgen and Orfanos in Germany, led to publications on both etretinates (Tigason) and isotretinoin (Roaccutane) in the years between 1972 and 1976 in the field of dermatology. In fact the first symposium on retinoid research held in Berlin in 1981 was almost entirely dermatological. A year later a retinoid workshop in Iowa was designed to provide a forum for dermatolog ists from the USA involved in specific protocols investigating oral retinoids. In the UK, research into the retinoids began rather later than in Continental Europe or in the USA, although Tigason was first marketed here. It was felt in late 1982 that as many dermatologists had relatively little experience with these compounds it would be appropriate to hold an International Symposium on retinoid therapy in the UK. Thus on 16-18 May 1983 in London, 37 speakers from 11 countries addressed an audience of 300, aminly UK, dermatologists. The scientific organizing committee consisted of but two persons Dr William Cunliffe of Leeds General Infirmary, representing the European Society of Dermatolo gical Research, and myself from Roche Clinical Research. The Symposium was held under the auspices of the ESDR and of Roche Products Limited.

Author : Hoffmann-La Roche Limited
Publisher : Oxford [England] : Medical Education Services
Page : 66 pages
File Size : 53,8 Mb
Release : 1984
Category : Etretinate
ISBN : 0886610168

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The Retinoids : a Significant Advance in Dermatology : Proceedings of a Symposium Held in Toronto, Canada, October 1983 by Hoffmann-La Roche Limited Pdf

Author : W. A. D. Griffiths
Publisher : Unknown
Page : 67 pages
File Size : 48,6 Mb
Release : 1995-01-01
Category : Dermatologic agents
ISBN : 1871211026

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Retinoids in Dermatology by W. A. D. Griffiths Pdf

Author : Maria Claudia Almeida Issa,Bhertha Tamura
Publisher : Springer
Page : 0 pages
File Size : 53,5 Mb
Release : 2017-08-11
Category : Medical
ISBN : 3319125885

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Daily Routine in Cosmetic Dermatology by Maria Claudia Almeida Issa,Bhertha Tamura Pdf

​The series “Clinical Approaches and Procedures in Cosmetic Dermatology” intends to be a practical guide in Cosmetic Dermatology. Procedures in cosmetic dermatology are very popular and useful in medicine, indicated to complement topical and oral treatments not only for photodamaged skin but also for other dermatosis such as acne, rosacea, scars, etc. Also, full-face treatments using peelings, lasers, fillers and toxins are increasingly being used, successfully substituting or postponing the need for plastic surgeries. Altogether, these techniques not only provide immediate results but also help patients to sustain long-term benefits, both preventing/treating dermatological diseases and maintaining a healthy and youthful skin. Throughout this series, different treatments in Cosmetic Dermatology will be discussed in detail covering the use of many pharmacological groups of cosmeceuticals, the new advances in nutraceuticals and emerging technologies and procedures. This volume, entitled “Daily Routine in Cosmetic Dermatology” will be an important tool for aesthetic doctors, practicing dermatologists, plastic surgeons, and all other physicians interested in the field of aesthetic medicine. It discloses in detail the semiology and general treatments in cosmetic dermatology, providing the state-of-the-art regarding patients’ evaluation, photoprotection, nutraceuticals and cosmeceuticals and special prescriptions. Also check the other volumes: Volume II - Chemical and Physical Peelings Volume III - Lasers, Lights and Other Technologies Volume IV - Botulinum Toxins, Fillers and Related Substances

Author : Guy F. Webster,Anthony V. Rawlings
Publisher : CRC Press
Page : 336 pages
File Size : 46,5 Mb
Release : 2007-05-17
Category : Medical
ISBN : 9781420018417

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Acne and Its Therapy by Guy F. Webster,Anthony V. Rawlings Pdf

Addressing one of the most commonly encountered conditions seen by the dermatologist, this source analyzes the pathophysiology, evaluation, diagnosis, clinical features, and control of acne. With full-color illustrations, this source delves into the available treatment options for difficult cases of acne and scarring and provides expert discussions

Author : Leslie S. Baumann
Publisher : McGraw Hill Professional
Page : 364 pages
File Size : 48,8 Mb
Release : 2014-10-22
Category : Medical
ISBN : 9780071793995

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Cosmeceuticals and Cosmetic Ingredients by Leslie S. Baumann Pdf

UNDERSTAND WHAT INGREDIENTS WORK FOR VARIOUS SKIN TYPES AND WHY WITH THE HELP OF THIS UNIQUE TEXT Cosmeceuticals and Cosmetic Ingredients helps skin-care professionals understand topical drug delivery through cosmeceuticals, the scientific basis of cosmetic ingredients, and the challenges of using either in a skin care regimen. The author addresses myths and misconseptions about specific ingredients and carefully details what each can and cannot do. It provides an unbiased brandneutralapproach along with detailed information and references to published evidence. Cosmeceuticals and Cosmetic Ingredients is logically divided into ten sections: Cleansing Agents Moisturizing Agents Barrier Repair Ingredients Skin Lightening Agents Antioxidants Vitamins Other Ingredients (Coenzyme Q10, Ginger, Honey, etc.) Anti-Inflammatory Agents Anti-Acne Ingredients Anti-Aging Ingredients

Author : Constantin E. Orfanos,Rudolf Schuppli
Publisher : Unknown
Page : 72 pages
File Size : 49,8 Mb
Release : 1978
Category : Retinoids
ISBN : UOM:39015013798460

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Oral Retinoids in Dermatology by Constantin E. Orfanos,Rudolf Schuppli Pdf

Author : Jean-Hilaire Saurat
Publisher : S. Karger AG (Switzerland)
Page : 536 pages
File Size : 46,9 Mb
Release : 1985
Category : Medical
ISBN : UOM:39015010662677

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Retinoids, New Trends in Research and Therapy by Jean-Hilaire Saurat Pdf

Author : Dae Hun Suh
Publisher : Springer Nature
Page : 194 pages
File Size : 55,9 Mb
Release : 2021-08-20
Category : Medical
ISBN : 9783030689964

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Acne by Dae Hun Suh Pdf

This book brings together world-famous acne researchers and specialists to compile a source of comprehensive, state-of-the-art information for management of acne. It examines acne as a chronic skin disease from pathogenesis to treatment. The book covers the clinical aspects of acne, topical treatments, light therapies, environmental factors and more alongside real patient photos from around the world. Treatments that chapters explore include photodynamic therapy and topical retinoids. In addition to genetic and hormonal causes of acne, chapters also include discussions on the connections between acne and diet, and acne and environmental factors. International contributors make this text unique in that it can focus solely on acne but also include international factors. Throughout the text, authors present the most up-to-date knowledge of acne pathophysiology, clinical features, differential diagnosis, treatment, and more. Pathophysiology, in particular, includes information on bacteria, immunity, endocrinologic factors, various deteriorating factors and environmental factors. As for clinical features, adult acne, differences in clinical patterns by region and race, and acne fulminans are covered. Regarding treatment, the latest knowledge on existing treatments or treatment methods, new drugs, and core outcome measures are mentioned. Acne: Current Concepts and Management is written for the dermatologist community from resident to researcher to privately practicing clinician.