Rna Turnover In Eukaryotes Nucleases Pathways And Analysis Of Mrna Decay

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RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay

Author : Lynne E. Maquat,Megerditch Kiledjian
Publisher : Academic Press
Page : 656 pages
File Size : 47,6 Mb
Release : 2009-01-30
Category : Science
ISBN : 0080922074

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RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay by Lynne E. Maquat,Megerditch Kiledjian Pdf

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover, which are central to the process of gene expression Offers step-by-step lab instructions, including necessary equipment and reagents

RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways

Author : Lynne E. Maquat,Megerditch Kiledjian
Publisher : Academic Press
Page : 463 pages
File Size : 55,6 Mb
Release : 2011-09-02
Category : Science
ISBN : 9780080923321

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RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways by Lynne E. Maquat,Megerditch Kiledjian Pdf

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway Expert researchers introduce the most advanced technologies and techniques Offers step-by-step lab instructions, including necessary equipment and reagents

RNA Exosome

Author : Torben Heick Jensen
Publisher : Springer Science & Business Media
Page : 161 pages
File Size : 50,9 Mb
Release : 2011-06-29
Category : Medical
ISBN : 9781441978417

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RNA Exosome by Torben Heick Jensen Pdf

The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.

Laboratory Methods in Enzymology: RNA

Author : Jon Lorsch
Publisher : Academic Press
Page : 472 pages
File Size : 44,6 Mb
Release : 2013-09-11
Category : Science
ISBN : 9780124200517

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Laboratory Methods in Enzymology: RNA by Jon Lorsch Pdf

Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on RNA, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. Indispensable tool for the researcher Carefully written and edited by experts to contain step-by-step protocols In this volume we have brought together a number of core protocols concentrating on RNA

Imaging and Spectroscopic Analysis of Living Cells

Author : P. Michael Conn
Publisher : Academic Press
Page : 559 pages
File Size : 52,5 Mb
Release : 2012
Category : Cell physiology
ISBN : 9780123918567

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Imaging and Spectroscopic Analysis of Living Cells by P. Michael Conn Pdf

This volume of Methods in Enzymology is the third of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike. Publisher's note.

Imaging and Spectroscopic Analysis of Living Cells

Author : Anonim
Publisher : Academic Press
Page : 576 pages
File Size : 50,9 Mb
Release : 2012-03-15
Category : Medical
ISBN : 9780123919076

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Imaging and Spectroscopic Analysis of Living Cells by Anonim Pdf

This volume of Methods in Enzymology is the second of three parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike. Expert authors who are leaders in the field Extensively referenced and useful figures and tables Provides hints and tricks to facilitate reproduction of methods

RNA Helicases

Author : Eckhard Jankowsky
Publisher : Academic Press
Page : 590 pages
File Size : 53,5 Mb
Release : 2012-06-22
Category : Medical
ISBN : 9780123965462

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RNA Helicases by Eckhard Jankowsky Pdf

This work integrates the current knowledge about RNA helicases from diverse fields ranging from cell and developmental biology to mechanistic enzymology and structural biology into one useful resource.

Laboratory Methods in Enzymology: DNA

Author : Anonim
Publisher : Elsevier
Page : 405 pages
File Size : 48,7 Mb
Release : 2013-09-02
Category : Science
ISBN : 9780124199545

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Laboratory Methods in Enzymology: DNA by Anonim Pdf

Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on DNA, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. Indispensable tool for the researcher Carefully written and edited by experts to contain step-by-step protocols In this volume we have brought together a number of core protocols concentrating on DNA

Natural Product Biosynthesis by Microorganisms and Plants Part B

Author : Anonim
Publisher : Academic Press
Page : 463 pages
File Size : 55,7 Mb
Release : 2012-10-01
Category : Science
ISBN : 9780123946287

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Natural Product Biosynthesis by Microorganisms and Plants Part B by Anonim Pdf

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants. This new volume continues the legacy of this premier serial Contains quality chapters authored by leaders in the field The second of 3 volumes it has chapters on such topics as biological chlorination, bromination and iodination, and phylogenetic approaches to natural product structure prediction

Ghrelin

Author : Anonim
Publisher : Academic Press
Page : 519 pages
File Size : 54,6 Mb
Release : 2012-12-17
Category : Science
ISBN : 9780123812735

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Ghrelin by Anonim Pdf

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volume covers ghrelin, and has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice. Contains quality chapters authored by leaders in the field Has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice

Cilia, Part B

Author : Anonim
Publisher : Academic Press
Page : 497 pages
File Size : 49,5 Mb
Release : 2013-03-16
Category : Science
ISBN : 9780123984852

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Cilia, Part B by Anonim Pdf

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers cilia Contains chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins

Research Methods in Biomineralization Science

Author : Anonim
Publisher : Elsevier
Page : 703 pages
File Size : 55,9 Mb
Release : 2013-10-31
Category : Science
ISBN : 9780124166554

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Research Methods in Biomineralization Science by Anonim Pdf

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in biomineralization science, and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Contains sections on such topics as and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure

Natural Product Biosynthesis by Microorganisms and Plants

Author : D. A. Hopwood
Publisher : Academic Press
Page : 488 pages
File Size : 47,6 Mb
Release : 2012
Category : Alkaloids
ISBN : 9780123942906

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Natural Product Biosynthesis by Microorganisms and Plants by D. A. Hopwood Pdf

Annotation This volume of 'Methods in Enzymology' continues the legacy of this premier serial by containing quality chapters authored by leaders in the field.

Nucleosomes, Histones and Chromatin Part B

Author : Anonim
Publisher : Academic Press
Page : 429 pages
File Size : 47,6 Mb
Release : 2012-12-31
Category : Science
ISBN : 9780123919397

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Nucleosomes, Histones and Chromatin Part B by Anonim Pdf

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volume covers nucleosomes, histones and chromatin and has chapters on dynamic mapping of histone-DNA interactions in nucleosomes by unzipping single molecules of DNA, digital DNase technology, and genome-wide analysis of chromatin transition. Contains quality chapters authored by leaders in the field The volume covers nucleosomes, histones and chromatin Has chapters on dynamic mapping of histone-DNA interactions in nucleosomes by unzipping single molecules of DNA, digital DNase technology, and genome-wide analysis of chromatin transition

Natural Product Biosynthesis by Microorganisms and Plants, Part A

Author : Anonim
Publisher : Academic Press
Page : 487 pages
File Size : 42,6 Mb
Release : 2012-12-31
Category : Science
ISBN : 9780123946270

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Natural Product Biosynthesis by Microorganisms and Plants, Part A by Anonim Pdf

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The first of 3 volumes covering Natural product biosynthesis by microorganisms and plants, it has chapters on such topics as Kinetics of plant sesquiterpene synthases, Terpenoid biosynthesis in fungi, and plant Type III polyketide synthases. Contains quality chapters authored by leaders in the field The first of 3 volumes Has chapters on such topics as kinetics of plant sesquiterpene synthases, terpenoid biosynthesis in fungi, and plant Type III polyketide synthases