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Author : Thomas R. Cech,Joan A. Steitz,John F. Atkins
Publisher : Unknown
Page : 580 pages
File Size : 54,5 Mb
Release : 2018-12-31
Category : Science
ISBN : 1621822249
"A Subject Collection from Cold Spring Harbor Perspectives in Biology."
Author : Michael Yarus
Publisher : Harvard University Press
Page : 212 pages
File Size : 45,6 Mb
Release : 2010
Category : Science
ISBN : 0674050754
A majority of evolutionary biologists believe that we now can envision our biological predecessors--not the first, but nearly the first, living beings on Earth. This book is about these vanished forebears. The era between the first rudimentary life on Earth and the appearance of more complex beings is called the RNA world. It is RNA (ribonucleic acid) long believed to be a mere biologic copier and messenger, that offers a glimpse into our ancient predecessors. To describe early RNA creatures, here called "ribocytes" or RNA cells, the author uses basics of molecular biology. He reviews our current understanding of the tree of life, examines the structure of RNA itself, explains the operation of the genetic code, and more. Courting controversy among those who question the role of ribocytes -- citing the chemical fragility of RNA and the uncertainty about the origin of an RNA synthetic apparatus -- he offers a vision of early life on Earth.
Author : Raymond F. Gesteland,Thomas Cech,John Fuller Atkins
Publisher : Unknown
Page : 744 pages
File Size : 52,6 Mb
Release : 1999
Category : Science
ISBN : UOM:39015050027823
Author : John F. Atkins,Raymond F. Gesteland,Thomas Cech,Cold Spring Harbor Laboratory. Press
Publisher : Unknown
Page : 0 pages
File Size : 48,6 Mb
Release : 2011
Category : Science
ISBN : 0879699469
This volume reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate.
Author : Laura L Mays Hoopes
Publisher : Lulu.com
Page : 172 pages
File Size : 55,5 Mb
Release : 2019-03-08
Category : Biography & Autobiography
ISBN : 9780359485208
A dual biography of Joan Steitz and Jennifer Doudna, two women who combined successful home lives with successful careers in science.
Author : Thomas Cech,Joan A. Steitz,John Fuller Atkins
Publisher : Unknown
Page : 559 pages
File Size : 49,5 Mb
Release : 2019
Category : Electronic
ISBN : 1621823539
Author : Raymond F. Gesteland,Thomas Cech,John F. Atkins
Publisher : CSHL Press
Page : 774 pages
File Size : 45,9 Mb
Release : 2006
Category : Science
ISBN : 9780879697396
Recent studies on the activities of RNA in the cell have revolutionized our understanding of the many roles played by this molecule. The first two editions of The RNA World(1993, 1999) shed light on the pre–biotic era dominated by this versatile molecule, and provided an overview of the state of RNA research at the time. The new third edition of The RNA Worldupdates this perspective, describing the vast array of newly discovered roles for RNA in the modern world. The updated original chapters are supplemented with new chapters on RNA–protein complexes, snRNPs and snoRNPs, telomerase RNA, RNAi, microRNAs, noncoding RNA, and many other subjects. This book is essential reading for anyone interested in the biology of nucleic acids and gene regulation and a valuable resource for teaching these concepts.
Author : Ashraf - Ali,André Canosa,David Leisawitz
Publisher : Frontiers Media SA
Page : 170 pages
File Size : 40,9 Mb
Release : 2022-09-26
Category : Science
ISBN : 9782832500736
Author : David Malcolm James Lilley,Fritz Eckstein
Publisher : Royal Society of Chemistry
Page : 339 pages
File Size : 40,7 Mb
Release : 2008
Category : Science
ISBN : 9780854042531
Takes the reader through the origins of catalysis in RNA and necessarily includes significant discussion of structure and folding. The main focus of the book concerns chemical mechanism with extensive comment on how, despite the importance of RNA catalysis in the cell, its origins are still poorly understood and often controversial. The reader is given an outline of the important role of RNA catalysis in many aspects of cell function, including RNA processing and translation.
Author : Matthew Cobb
Publisher : Profile Books
Page : 728 pages
File Size : 47,5 Mb
Release : 2015-06-11
Category : History
ISBN : 9781782830023
Life's Greatest Secret is the story of the discovery and cracking of the genetic code. This great scientific breakthrough has had far-reaching consequences for how we understand ourselves and our place in the natural world. The code forms the most striking proof of Darwin's hypothesis that all organisms are related, holds tremendous promise for improving human well-being, and has transformed the way we think about life. Matthew Cobb interweaves science, biography and anecdote in a book that mixes remarkable insights, theoretical dead-ends and ingenious experiments with the pace of a thriller. He describes cooperation and competition among some of the twentieth century's most outstanding and eccentric minds, moves between biology, physics and chemistry, and shows the part played by computing and cybernetics. The story spans the globe, from Cambridge MA to Cambridge UK, New York to Paris, London to Moscow. It is both thrilling science and a fascinating story about how science is done.
Author : Axel Meyer,Yves van de Peer
Publisher : Springer Science & Business Media
Page : 242 pages
File Size : 54,6 Mb
Release : 2011-06-28
Category : Science
ISBN : 9789401002639
In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation. This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.
Author : John Hudson Tiner
Publisher : New Leaf Publishing Group
Page : 275 pages
File Size : 50,5 Mb
Release : 2009-01-28
Category : Juvenile Nonfiction
ISBN : 9780890515525
This book in Master Books Exploring series is a fascinating look at life--from the smallest proteins and spores, to the complex life systems of humans and animals.
Author : James E. Darnell
Publisher : Unknown
Page : 0 pages
File Size : 43,8 Mb
Release : 2011
Category : Science
ISBN : 1936113198
RNA molecules could function as catalysts. --
Author : Shabir H. Wani,Vinay Kumar
Publisher : John Wiley & Sons
Page : 315 pages
File Size : 50,8 Mb
Release : 2020-04-06
Category : Science
ISBN : 9781119432364
Demystifies the genetic, biochemical, physiological, and molecular mechanisms underlying heat stress tolerance in plants Heat stress—when high temperatures cause irreversible damage to plant function or development—severely impairs the growth and yield of agriculturally important crops. As the global population mounts and temperatures continue to rise, it is crucial to understand the biochemical, physiological, and molecular mechanisms of thermotolerance to develop ‘climate-smart’ crops. Heat Stress Tolerance in Plants provides a holistic, cross-disciplinary survey of the latest science in this important field. Presenting contributions from an international team of plant scientists and researchers, this text examines heat stress, its impact on crop plants, and various mechanisms to modulate tolerance levels. Topics include recent advances in molecular genetic approaches to increasing heat tolerance, the potential role of biochemical and molecular markers in screening germplasm for thermotolerance, and the use of next-generation sequencing to unravel the novel genes associated with defense and metabolite pathways. This insightful book: Places contemporary research on heat stress in plants within the context of global climate change and population growth Includes diverse analyses from physiological, biochemical, molecular, and genetic perspectives Explores various approaches to increasing heat tolerance in crops of high commercial value, such as cotton Discusses the applications of plant genomics in the development of thermotolerant ‘designer crops’ An important contribution to the field, Heat Stress Tolerance in Plants is an invaluable resource for scientists, academics, students, and researchers working in fields of pulse crop biochemistry, physiology, genetics, breeding, and biotechnology.
Author : Sabine Müller,Benoît Masquida,Wade Winkler
Publisher : John Wiley & Sons
Page : 81 pages
File Size : 42,9 Mb
Release : 2021-07-09
Category : Science
ISBN : 9783527814534
Ribozymes Provides comprehensive coverage of a core field in the molecular biosciences, bringing together decades of knowledge from the world’s top professionals in the field Timely and unique in its breadth of content, this all-encompassing and authoritative reference on ribozymes documents the great diversity of nucleic acid-based catalysis. It integrates the knowledge gained over the past 35 years in the field and features contributions from virtually every leading expert on the subject. Ribozymes is organized into six major parts. It starts by describing general principles and strategies of nucleic acid catalysis. It then introduces naturally occurring ribozymes and includes the search for new catalytic motifs or novel genomic locations of known motifs. Next, it covers the development and design of engineered ribozymes, before moving on to DNAzymes as a close relative of ribozymes. The next part examines the use of ribozymes for medicinal and environmental diagnostics, as well as for therapeutic tools. It finishes with a look at the tools and methods in ribozyme research, including the techniques and assays for structural and functional characterization of nucleic acid catalysts. The first reference to tie together all aspects of the multi-faceted field of ribozymes Features more than 30 comprehensive chapters in two volumes Covers the chemical principles of RNA catalysis; naturally occurring ribozymes, engineered ribozymes; DNAzymes; ribozymes as tools in diagnostics and therapy, and tools and methods to study ribozymes Includes first-hand accounts of concepts, techniques, and applications by a team of top international experts from leading academic institutions Dedicates half of its content to methods and practical applications, ranging from bioanalytical tools to medical diagnostics to therapeutics Ribozymes is an unmatched resource for all biochemists, biotechnologists, molecular biologists, and bioengineers interested in the topic.
