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Author : Thomas R. Cech,Joan A. Steitz,John F. Atkins
Publisher : Unknown
Page : 580 pages
File Size : 52,5 Mb
Release : 2018-12-31
Category : Science
ISBN : 1621822249
"A Subject Collection from Cold Spring Harbor Perspectives in Biology."
Author : Raymond F. Gesteland,Thomas Cech,John Fuller Atkins
Publisher : Unknown
Page : 744 pages
File Size : 54,8 Mb
Release : 1999
Category : Science
ISBN : UOM:39015050027823
Author : Michael Yarus
Publisher : Harvard University Press
Page : 212 pages
File Size : 52,8 Mb
Release : 2010
Category : Science
ISBN : 0674050754
A majority of evolutionary biologists believe that we now can envision our biological predecessors--not the first, but nearly the first, living beings on Earth. This book is about these vanished forebears. The era between the first rudimentary life on Earth and the appearance of more complex beings is called the RNA world. It is RNA (ribonucleic acid) long believed to be a mere biologic copier and messenger, that offers a glimpse into our ancient predecessors. To describe early RNA creatures, here called "ribocytes" or RNA cells, the author uses basics of molecular biology. He reviews our current understanding of the tree of life, examines the structure of RNA itself, explains the operation of the genetic code, and more. Courting controversy among those who question the role of ribocytes -- citing the chemical fragility of RNA and the uncertainty about the origin of an RNA synthetic apparatus -- he offers a vision of early life on Earth.
Author : Raymond F. Gesteland,Thomas Cech,John F. Atkins
Publisher : CSHL Press
Page : 774 pages
File Size : 41,6 Mb
Release : 2006
Category : Science
ISBN : 9780879697396
Recent studies on the activities of RNA in the cell have revolutionized our understanding of the many roles played by this molecule. The first two editions of The RNA World(1993, 1999) shed light on the pre–biotic era dominated by this versatile molecule, and provided an overview of the state of RNA research at the time. The new third edition of The RNA Worldupdates this perspective, describing the vast array of newly discovered roles for RNA in the modern world. The updated original chapters are supplemented with new chapters on RNA–protein complexes, snRNPs and snoRNPs, telomerase RNA, RNAi, microRNAs, noncoding RNA, and many other subjects. This book is essential reading for anyone interested in the biology of nucleic acids and gene regulation and a valuable resource for teaching these concepts.
Author : Laura L Mays Hoopes
Publisher : Lulu.com
Page : 172 pages
File Size : 42,6 Mb
Release : 2019-03-08
Category : Biography & Autobiography
ISBN : 9780359485208
A dual biography of Joan Steitz and Jennifer Doudna, two women who combined successful home lives with successful careers in science.
Author : John F. Atkins,Raymond F. Gesteland,Thomas Cech,Cold Spring Harbor Laboratory. Press
Publisher : Unknown
Page : 0 pages
File Size : 55,9 Mb
Release : 2011
Category : Science
ISBN : 0879699469
This volume reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate.
Author : Ulrich C. Schreiber,Christian Mayer
Publisher : Springer Nature
Page : 186 pages
File Size : 53,5 Mb
Release : 2020-06-05
Category : Science
ISBN : 9783030453817
This book introduces a fresh perspective on the conditions for the genesis of the first cell. An important possible environment of the prehistoric Earth has long been overlooked as a host to the perfect biochemical conditions for this process. The first complexes of continental crust on the early Earth must have already contained systems of interconnected cracks and cavities, which were filled with volatiles like water, carbon dioxide and nitrogen. This book offers insights into how these conditions may have provided the ideal physical and chemical setting for the formation of protocells and early stages of life. The authors support their hypothesis with a number of astonishing findings from laboratory experiments focusing on a variety of organic compounds, and on the formation of key cellular ingredients and of primitive cell-like structures. Moreover, they discuss the principles of prebiotic evolution regarding the aspects of order and complexity. Guiding readers through various stages of hypotheses and re-created evolutionary processes, the book is enriched with personal remarks and experiences throughout, reflecting the authors' personal quest to solve the mystery surrounding the first cell.
Author : David Malcolm James Lilley,Fritz Eckstein
Publisher : Royal Society of Chemistry
Page : 339 pages
File Size : 43,9 Mb
Release : 2008
Category : Science
ISBN : 9780854042531
Takes the reader through the origins of catalysis in RNA and necessarily includes significant discussion of structure and folding. The main focus of the book concerns chemical mechanism with extensive comment on how, despite the importance of RNA catalysis in the cell, its origins are still poorly understood and often controversial. The reader is given an outline of the important role of RNA catalysis in many aspects of cell function, including RNA processing and translation.
Author : Gesteland
Publisher : Unknown
Page : 768 pages
File Size : 50,9 Mb
Release : 2006-01-01
Category : Electronic
ISBN : 818823799X
Recent studies on the activities of RNA in the cell have revolutionized our understanding of the many roles played by this molecule. The first two editions of The RNA World (1993, 1999) shed light on the pre biotic era dominated by this versatile molecule, and provided an overview of the state of RNA research at the time. The new third edition of The RNA World updates this perspective, describing the vast array of newly discovered roles for RNA in the modern world. The updated original chapters are supplemented with new chapters on RNA protein complexes, snRNPs and snoRNPs, telomerase RNA, RNAi, microRNAs, noncoding RNA, and many other subjects. This book is essential reading for anyone interested in the biology of nucleic acids and gene regulation and a valuable resource for teaching these concepts
Author : Sabine Müller,Benoît Masquida,Wade Winkler
Publisher : John Wiley & Sons
Page : 81 pages
File Size : 43,8 Mb
Release : 2021-07-09
Category : Science
ISBN : 9783527814534
Ribozymes Provides comprehensive coverage of a core field in the molecular biosciences, bringing together decades of knowledge from the world’s top professionals in the field Timely and unique in its breadth of content, this all-encompassing and authoritative reference on ribozymes documents the great diversity of nucleic acid-based catalysis. It integrates the knowledge gained over the past 35 years in the field and features contributions from virtually every leading expert on the subject. Ribozymes is organized into six major parts. It starts by describing general principles and strategies of nucleic acid catalysis. It then introduces naturally occurring ribozymes and includes the search for new catalytic motifs or novel genomic locations of known motifs. Next, it covers the development and design of engineered ribozymes, before moving on to DNAzymes as a close relative of ribozymes. The next part examines the use of ribozymes for medicinal and environmental diagnostics, as well as for therapeutic tools. It finishes with a look at the tools and methods in ribozyme research, including the techniques and assays for structural and functional characterization of nucleic acid catalysts. The first reference to tie together all aspects of the multi-faceted field of ribozymes Features more than 30 comprehensive chapters in two volumes Covers the chemical principles of RNA catalysis; naturally occurring ribozymes, engineered ribozymes; DNAzymes; ribozymes as tools in diagnostics and therapy, and tools and methods to study ribozymes Includes first-hand accounts of concepts, techniques, and applications by a team of top international experts from leading academic institutions Dedicates half of its content to methods and practical applications, ranging from bioanalytical tools to medical diagnostics to therapeutics Ribozymes is an unmatched resource for all biochemists, biotechnologists, molecular biologists, and bioengineers interested in the topic.
Author : Akihiko Yamagishi,Takeshi Kakegawa,Tomohiro Usui
Publisher : Springer
Page : 465 pages
File Size : 46,9 Mb
Release : 2019-02-27
Category : Science
ISBN : 9789811336393
This book provides concise and cutting-edge reviews in astrobiology, a young and still emerging multidisciplinary field of science that addresses the fundamental questions of how life originated and diversified on Earth, whether life exists beyond Earth, and what is the future for life on Earth. Readers will find coverage of the latest understanding of a wide range of fascinating topics, including, for example, solar system formation, the origins of life, the history of Earth as revealed by geology, the evolution of intelligence on Earth, the implications of genome data, insights from extremophile research, and the possible existence of life on other planets within and beyond the solar system. Each chapter contains a brief summary of the current status of the topic under discussion, sufficient references to enable more detailed study, and descriptions of recent findings and forthcoming missions or anticipated research. Written by leading experts in astronomy, planetary science, geoscience, chemistry, biology, and physics, this insightful and thought-provoking book will appeal to all students and scientists who are interested in life and space.
Author : James E. Darnell
Publisher : Unknown
Page : 0 pages
File Size : 45,7 Mb
Release : 2011
Category : Science
ISBN : 1936113198
RNA molecules could function as catalysts. --
Author : Aysha Divan,Janice Royds
Publisher : Oxford University Press
Page : 144 pages
File Size : 52,7 Mb
Release : 2016-08-18
Category : Science
ISBN : 9780191035814
Molecular Biology is the story of the molecules of life, their relationships, and how these interactions are controlled. It is an expanding field in life sciences, and its applications are wide and growing. We can now harness the power of molecular biology to treat diseases, solve crimes, map human history, and produce genetically modified organisms and crops, and these applications have sparked a multitude of fascinating legal and ethical debates. In this Very Short Introduction, Aysha Divan and Janice Royds examine the history, present, and future of Molecular Biology. Starting with the building blocks established by Darwin, Wallace and Mendel, and the discovery of the structure of DNA in 1953, they consider the wide range of applications for Molecular Biology today, including the development of new drugs, and forensic science. They also look forward to two key areas of evolving research such as personalised medicine and synthetic biology. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Author : Peter Walde
Publisher : Springer Science & Business Media
Page : 248 pages
File Size : 49,9 Mb
Release : 2005-10-13
Category : Science
ISBN : 3540277595
Author : A. I. Oparin,A. E. Braunshteĭn,A. G. Pasynskiĭ
Publisher : Elsevier
Page : 731 pages
File Size : 40,7 Mb
Release : 2013-09-03
Category : Science
ISBN : 9781483222400
The Origin of Life on the Earth covers the proceedings of the First International Symposium of The Origin of Life on the Earth, held at Moscow on August 19-24, 1957. This symposium brings together numerous scientific studies on the evolutionary principles and the different stages in the evolutionary development of matter. This book is organized into seven parts encompassing 60 chapters. The first parts discuss evidence that on the formation of hydrocarbons and their derivatives on the surface of the Earth even before the emergence of life. The subsequent parts are devoted to the many asymmetrical syntheses under the influence of circularly-polarized ultraviolet light, by catalytic reactions occurring on the surface of quartz crystals, and spontaneously by slow crystallization from solutions. These topics are followed by reviews on the possible means of abiogenic formation of amino acids, porphyrins, protein-like polymers, polynucleotides and other high-molecular organic compounds. Considerable chapters explore the complete possibility of the primary formation of these compounds on the surface of the Earth even before life was present on it. Other general topics covered include nucleic acids, nucleoproteins and viruses. The last part considers general biochemical problems connected with the further development of metabolism. This book will be of value to astronomers, physicists, geologists, chemists, and biologists.
