Science Of Synthesis Biocatalysis In Organic Synthesis Vol 2

Author : Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner
Publisher : Thieme
Page : 1000 pages
File Size : 54,8 Mb
Release : 2015-03-11
Category : Science
ISBN : 9783131766410

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Science of Synthesis: Biocatalysis in Organic Synthesis Vol. 2 by Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner Pdf

The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 2 covers reactions involving the formation of C-C bonds. Addition of carbon nucleophiles at C-O and C-N double bonds are reviewed, as are methods for the formation of C-C bonds at arenes and additions to C-C double bonds. Other chapters present transamination and reductive amination reactions, reduction of carbonyl compounds, and the uses of epoxides in biocatalysis.

Author : Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner
Publisher : Unknown
Page : 0 pages
File Size : 49,8 Mb
Release : 2015
Category : Biocatalysis
ISBN : 3132028711

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Science of Synthesis by Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner Pdf

The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis.

Author : Kurt Faber,Wolf-Dieter Fessner,N. J. Turner
Publisher : Thieme/Houben-Weyl Series
Page : 0 pages
File Size : 45,5 Mb
Release : 2015
Category : Science
ISBN : 3131741619

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Biocatalysis in Organic Synthesis by Kurt Faber,Wolf-Dieter Fessner,N. J. Turner Pdf

The three Science of Synthesis volumes on Biocatalysis in Organic Synthesis present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. Biocatalysis in Organic Synthesis offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 2 covers reactions involving the formation of C-C bonds. Addition of carbon nucleophiles at C-O and C-N double bonds are reviewed, as are methods for the formation of C-C bonds at arenes and additions to C-C double bonds. Other chapters present transamination and reductive amination reactions, reduction of carbonyl compounds, and the uses of epoxides in biocatalysis.

Author : G. A. Molander
Publisher : Thieme
Page : 508 pages
File Size : 43,8 Mb
Release : 2020-05-22
Category : Science
ISBN : 9783132429833

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Science of Synthesis: Dual Catalysis in Organic Synthesis 2 by G. A. Molander Pdf

The field of dual catalysis has developed rapidly over the last decade, and these volumes define its impact on organic synthesis. The most important, basic concepts of synergistic, dual catalytic cycles are introduced, providing newcomers to the field with reliable information on this new approach to facilitating the synthesis of organic molecules. Background information and reliable procedures for challenging transformations in synthesis are presented, applying the concept of cooperative dual catalysis as a means of increasing molecular complexity in the most efficient manner. The most useful, practical, and reliable methods for dual catalysis combining metal catalysts, organocatalysts, photocatalysts, and biocatalysts are presented.

Author : Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner
Publisher : Thieme
Page : 944 pages
File Size : 42,7 Mb
Release : 2015-03-11
Category : Science
ISBN : 9783131766618

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Science of Synthesis: Biocatalysis in Organic Synthesis Vol. 3 by Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner Pdf

The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 3 begins with oxidation. A chapter on enzyme-catalyzed dihydroxylation is followed by reviews of alkane oxidation. Oxidations of alcohols, carbonyl compounds, and heteroatoms are covered, as are halogenations. The use of biocatalysts in total synthesis, cascade reactions, and large-scale industrial applications is considered. Finally, emerging trends are discussed.

Author : Nicholas J. Turner,Luke Humphreys
Publisher : Royal Society of Chemistry
Page : 416 pages
File Size : 51,9 Mb
Release : 2018-02-08
Category : Science
ISBN : 9781782625308

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Biocatalysis in Organic Synthesis by Nicholas J. Turner,Luke Humphreys Pdf

The application of biocatalysis in organic synthesis is rapidly gaining popularity amongst chemists. Compared to traditional synthetic methodologies biocatalysis offers a number of advantages in terms of enhanced selectivity (chemo-, regio-, stereo-), reduced environmental impact and lower cost of starting materials. Together these advantages can contribute to more sustainable manufacturing processes across a wide range of industries ranging from pharmaceuticals to biofuels. The biocatalytic toolbox has expanded significantly in the past five years and given the current rate of development of new engineered biocatalysts it is likely that the number of available biocatalysts will double in the next few years. This textbook gives a comprehensive overview of the current biocatalytic toolbox and also establishes new guidelines or rules for “biocatalytic retrosynthesis”. Retrosynthesis is a well known and commonly used technique whereby organic chemists start with the structure of their target molecule and generate potential starting materials and intermediates through a series of retrosynthetic disconnections. These disconnections are then used to devise a forward synthesis, in this case using biocatalytic transformations in some of the key steps. Target molecules are disconnected with consideration for applying biocatalysts, as well as chemical reagents and chemocatalysts, in the forward synthesis direction. Using this textbook, students will be able to place biocatalysis within the context of other synthetic transformations that they have learned earlier in their studies. This additional awareness of biocatalysis will equip students for the modern world of organic synthesis where biocatalysts play an increasingly important role. In addition to guidelines for identifying where biocatalysts can be applied in organic synthesis, this textbook also provides examples of current applications of biocatalysis using worked examples and case studies. Tutorials enable the reader to practice disconnecting target molecules to find the ‘hidden’ biocatalytic reactions which can be applied in the synthetic direction. The book contains a complete description of the current biocatalyst classes that are available for use and also suggests areas where new enzymes are likely to be developed in the next few years. This textbook is an essential resource for lecturers and students studying synthetic organic chemistry. It also serves as a handy reference for practicing chemists who wish to embed biocatalysis into their synthetic toolbox.

Author : Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner
Publisher : Thieme
Page : 997 pages
File Size : 55,5 Mb
Release : 2015-03-11
Category : Science
ISBN : 9783131766212

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Science of Synthesis: Biocatalysis in Organic Synthesis Vol. 1 by Kurt Faber,Wolf-Dieter Fessner,Nicholas J. Turner Pdf

The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 1 begins with chapters discussing the historical development of the field, sources of enzymes and appropriate selection of catalysts, and general strategies employed in biocatalysis. This is followed by reviews of the biocatalytic hydrolysis of various substrates. The volume concludes with chapters devoted to biocatalytic isomerizations, and the synthesis of glycosides.

Author : Animesh Goswami,Jon D. Stewart
Publisher : Academic Press
Page : 438 pages
File Size : 40,7 Mb
Release : 2015-09-06
Category : Science
ISBN : 9780124115422

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Organic Synthesis Using Biocatalysis by Animesh Goswami,Jon D. Stewart Pdf

Organic Synthesis Using Biocatalysis provides a concise background on the application of biocatalysis for the synthesis of organic compounds, including the important biocatalytic reactions and application of biocatalysis for the synthesis of organic compounds in pharmaceutical and non-pharmaceutical areas. The book provides recipes for carrying out various biocatalytic reactions, helping both newcomers and non-experts use these methodologies. It is written by experts in their fields, and provides both a current status and future prospects of biocatalysis in the synthesis of organic molecules. Provides a concise background of the application of biocatalysis for the synthesis of organic compounds Expert contributors present recipes for carrying out biocatalytic reactions, including subject worthy discussions on biocatalysis in organic synthesis, biocatalysis for selective organic transformation, enzymes as catalysis for organic synthesis, biocatalysis in Industry, including pharmaceuticals, and more Contains detailed, separate chapters that describe the application of biocatalysis

Author : Kurt Faber,Wolf-Dieter Fessner,Nicholas Turner
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 2015
Category : Biocatalysis
ISBN : 3131746718

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Biocatalysis in Organic Synthesis by Kurt Faber,Wolf-Dieter Fessner,Nicholas Turner Pdf

The three Science of Synthesis volumes on Biocatalysis in Organic Synthesis present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. Biocatalysis in Organic Synthesis offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 3 begins with oxidation. A chapter on enzyme-catalyzed dihydroxylation is followed by reviews of alkane oxidation. Oxidations of alcohols, carbonyl compounds, and heteroatoms are covered, as are halogenations. The use of biocatalysts in total synthesis, cascade reactions, and large-scale industrial applications is considered. Finally, emerging trends are discussed.

Author : G. A. Molander
Publisher : Thieme
Page : 490 pages
File Size : 55,6 Mb
Release : 2020-05-22
Category : Science
ISBN : 9783132429789

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Science of Synthesis: Dual Catalysis in Organic Synthesis 1 by G. A. Molander Pdf

The field of dual catalysis has developed rapidly over the last decade, and these volumes define its impact on organic synthesis. The most important, basic concepts of synergistic, dual catalytic cycles are introduced, providing newcomers to the field with reliable information on this new approach to facilitating the synthesis of organic molecules. Background information and reliable procedures for challenging transformations in synthesis are presented, applying the concept of cooperative dual catalysis as a means of increasing molecular complexity in the most efficient manner. The most useful, practical, and reliable methods for dual catalysis combining metal catalysts, organocatalysts, photocatalysts, and biocatalysts are presented.

Author : Johannes G. de Vries
Publisher : Thieme
Page : 723 pages
File Size : 45,5 Mb
Release : 2018-07-13
Category : Science
ISBN : 9783132406292

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Science of Synthesis: Catalytic Reduction in Organic Synthesis by Johannes G. de Vries Pdf

Catalytic reductions are among the most used synthetic transformations, and the past 15 years have seen great progress in this field. Science of Synthesis: Catalytic Reduction in Organic Synthesis includes the latest developments, as well as selective coverage of more well-established methods. Both heterogeneous and homogeneous catalytic systems are covered, and enantioselective methodology is well represented. There is a focus on the use of metal nanoparticles, both in suspension as well as on solid supports. Furthermore, the advent of research on the conversion of renewable resources into fuels and chemicals has given a great impetus to the field, as deoxygenations are often the first step in the conversion of biomass and this can often be achieved using hydrogenation or hydrogenolysis reactions. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included.

Author : Steven Nolan,Catherine Cazin
Publisher : Thieme
Page : 816 pages
File Size : 45,5 Mb
Release : 2017-06-14
Category : Science
ISBN : 9783132414037

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Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 2 by Steven Nolan,Catherine Cazin Pdf

The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis" presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.

Author : Timothy Jamison,Guido Koch
Publisher : Unknown
Page : 0 pages
File Size : 50,9 Mb
Release : 2018
Category : Electronic
ISBN : 3132423335

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Science of Synthesis: Flow Chemistry in Organic Synthesis by Timothy Jamison,Guido Koch Pdf

Author : S. Sarel
Publisher : Elsevier
Page : 144 pages
File Size : 44,5 Mb
Release : 2018-01-23
Category : Science
ISBN : 9781483152097

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Organic Synthesis - 2 by S. Sarel Pdf

Organic Synthesis — 2 consists of plenary lectures presented at the Second International Symposium on Organic Synthesis, held in Jerusalem-Haifa, Israel, on September 10-15, 1978. The papers explore advances that have been made in organic synthesis and cover topics ranging from methods in peptide synthesis based on supernucleophiles to the use of palladium catalysts in natural products synthesis; asymmetric carbon-carbon bond forming reactions; asymmetric synthesis of chiral dimers and polymers with quantitative enantiomeric yield; and reactions based on the onium salts of azaaromatics. This volume is comprised of 10 chapters and begins with a discussion on some protecting group techniques and synthetic methods for peptides based on supernucleophiles. The reader is then introduced to the use of palladium catalyzed reactions in the synthesis of natural products; synthesis of 3aH-indenes and their heterocyclic analogues; alternatives to oxidative phenolic coupling in natural products total synthesis; and the occurrence of steric and electronic effects during reactions of propellanes. The final chapter deals with alpha-alkali-metalated isocyanides in organic synthesis. This book will be a useful resource for organic chemists.

Author : William A. Smit,Alekseĭ Feodosʹevich Bochkov,Ron Caple
Publisher : Royal Society of Chemistry
Page : 508 pages
File Size : 46,8 Mb
Release : 1998
Category : Education
ISBN : 0854045449

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Organic Synthesis by William A. Smit,Alekseĭ Feodosʹevich Bochkov,Ron Caple Pdf

The view of organic synthesis as "a concentrated expression of predictive ability and creative capacity" was advocated in the early 1950s. A concise and readable account of the role of synthesis in modern science, Organic Synthesis: The Science Behind the Art presents the general ideology of pursuits in the area of organic synthesis, and examines the methodologies that have evolved in the search for solutions to synthetic problems. This unique book details outstanding achievements of modern organic synthesis, not only for their scientific merits, but also for the aesthetic appeal of the target molecules chosen and the intrinsic beauty of the solutions to the problems posed. By judicious selection of data covering the main areas of synthetic explorations, this book serves to illustrate both the evolution of well-known approaches as well as recently emerged trends most likely to determine the future development of organic synthesis. Special attention is given to the consideration of principles of molecular design in promising and challenging areas of current research. Primarily aimed at advanced undergraduate and graduate students, Organic Synthesis: The Science Behind the Art will also be of interest to teachers, researchers and anyone requiring an introduction to the problems of organic synthesis.