Sclerosing Bone Dysplasias

Author : P. Beighton,B. J. Cremin
Publisher : Springer Science & Business Media
Page : 193 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447112921

Get Book

Sclerosing Bone Dysplasias by P. Beighton,B. J. Cremin Pdf

Much confusion exists in the accurate identification and classification of the many disorders in infancy which affect the skeleton by producing sclerosing lesions throughout the entire skeleton or in selected areas. A scholarly effort to bring order into this confusing field must be welcomed. Professors Beighton and Cremin have skillfully defined the problem and concisely yet thoroughly have identified the various sclerosing dysplasias. They bring to this task a wealth of clinical experience in their many years in the Departments of Radiology at the University of Cape Town Medical School and the Groote Schuur and Red Cross Children's Hospitals in Cape Town, South Africa. The authors also have had available data from the University of Cape Town Skeletal Dysplasia Registry. Professors Beighton and Cremin have used as a basis for their treatise the Paris Nomenclature (the modified version of 1977). This monograph is a felicitous combination of a working atlas and a scholarly exposition of the various sclerosing bone dysplasias, considering in detail eighteen major entities adopted from the Paris classification. Other disorders which present with osteosclerosis are also described. These include Caffey disease, oculodento-osseous dysplasia, central osteosclerosis with bamboo hair, fluorosis, osteosclerosis associated with renal disease and mastocytosis.

Author : Philip Rubin
Publisher : Unknown
Page : 434 pages
File Size : 42,7 Mb
Release : 1964
Category : Bones
ISBN : UOM:39015000868094

Get Book

Dynamic Classification of Bone Dysplasias by Philip Rubin Pdf

Author : Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi
Publisher : Academic Press
Page : 878 pages
File Size : 55,7 Mb
Release : 2017-10-31
Category : Medical
ISBN : 9780128041987

Get Book

Genetics of Bone Biology and Skeletal Disease by Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi Pdf

Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder

Author : Pauline M. Camacho
Publisher : Springer
Page : 271 pages
File Size : 40,7 Mb
Release : 2019-02-22
Category : Medical
ISBN : 9783030036942

Get Book

Metabolic Bone Diseases by Pauline M. Camacho Pdf

This concise, case-based text discusses the current state of the art for the diagnosis and management of metabolic bones diseases. Each chapter opens with a unique case presentation and utilizes a consistent format that includes relevant anatomy, physiology, and pathophysiology as well as examination, treatment approaches and clinical outcomes. Topics covered include osteoporosis, rickets and osteomalacia, hypoparathyroidism and pseudohypoparathyroidism, osteogenesis imperfecta, Paget's disease of bone, calcium and phosphorous disorders, hypophosphatasia, sclerotic bone disorders, fibrous and osteochondroplasia, and other malignancies of bone. Written and edited by experts in the field, Metabolic Bone Diseases is a valuable resource for practicing endocrinologists, rheumatologists and orthopedic surgeons, residents and fellows.

Author : Juliet E. Compston,Jane B. Lian
Publisher : John Wiley & Sons
Page : 559 pages
File Size : 40,6 Mb
Release : 2009-12-22
Category : Science
ISBN : 9780470623985

Get Book

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism by Juliet E. Compston,Jane B. Lian Pdf

EDITOR-IN-CHIEF: Clifford J. Rosen, M.D., Maine Medical Center Research Institute, Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, M.D., FRCP, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom Jane B. Lian, Ph.D., University of Massachusetts Medical School, Worcester, Massachusetts This comprehensive yet concise handbook is an indispensable reference for the many clinicians who see patients with disorders of bone formation, metabolic bone diseases, or disorders of stone formation. It is also a crucial tool for researchers, students, and all other professionals working in the bone field. In a format designed for quick reference, it provides complete information on the symptoms, pathophysiology, diagnosis, and treatment of all common and rare bone and mineral disorders. New in this edition: detailed coverage of osteonecrosis of the jaw, more in-depth coverage of cancer and bone including new approaches to pathogenesis, diagnosis, and treatment; new approaches to anabolic therapy of osteoporosis; the latest research on Vitamin D; expanded coverage of international topics; more on the genetics of bone mass; and newer imaging techniques for the skeleton. In addition, this edition features a free, online-only appendix of medicines used to treat bone disorders and their availability around the world.

Author : Jürgen W. Spranger,Paula W. Brill,Andrew K. Poznanski
Publisher : Oxford University Press, USA
Page : 306 pages
File Size : 52,7 Mb
Release : 2002
Category : Bone Diseases, Developmental
ISBN : 0195214749

Get Book

Bone Dysplasias by Jürgen W. Spranger,Paula W. Brill,Andrew K. Poznanski Pdf

Many advances have been made in understanding skeletal dysplasias since the first edition of this classic text appeared in 1974. The diagnostic process has been refined, many new disorders have been recognized, and the molecular aspects in many cases have been elucidated. The second edition has been completely renovated, with the help of two new co-authors, to incorporate these advances. The book's format is similar to the original but the number of conditions covered has almost doubled and molecular information has been added wherever available. The number of figures has been increased to the limit of economic wisdom. As in the first edition, the illustrations have been selected and sequenced to illustrate both the degree of variability of a given disorder and its changs with age. This book is designed for physicians involved in the evaluation and treatment of patients with skeletal dysplasias, including radiologists, medical geneticists, pediatricians, and orthopedic surgeons. Its main goal is to assist in the diagnosis of specific conditions and the care of affected individuals. Though mutations of specific genes can produce dysplasias with very different phenotypes and prognoses, the primarily clinical aim of this book dictated a phenotypic classification in general, with compromises on etiologic grounds where necessary. Since the attempt to diagnose a skeletal dysplasia from single signs, alone or in cominations, is fraught with errors, the authors focus on basic patterns of skeletal abnormalities.

Author : Jürgen W. Spranger,Paula W. Brill,Christine Hall,Gen Nishimura,Andrea Superti-Furga,Sheila Unger
Publisher : Oxford University Press
Page : 976 pages
File Size : 43,5 Mb
Release : 2018-10-25
Category : Medical
ISBN : 9780190626662

Get Book

Bone Dysplasias by Jürgen W. Spranger,Paula W. Brill,Christine Hall,Gen Nishimura,Andrea Superti-Furga,Sheila Unger Pdf

The definitive guide to genetic bone disorders, now revised and expanded with glossy photographs and radiographs "Brilliantly written and produced and deserves to be on the shelves of all pediatric radiologists. It should also be available to geneticists, counselors, and pediatricians." --Radiology This updated and expanded fourth edition of Bone Dysplasias presents age-related radiographs, photographs and clinical guidelines for more than 250 rare constitutional skeletal diseases. Focusing on diagnostically essential imaging and clinical features, each chapter is supplemented with prognostic and therapeutic information, a guide to differential diagnoses, and a short list of the most relevant publications. Organized in accordance with the most recent International Nosology and Classification of Genetic Skeletal Disorders, this new Bone Dysplasias distills the insights of a small, world-class author team on diagnosis and clinical approaches to this most difficult class of disorders.

Author : Roger Smith,Paul Wordsworth
Publisher : Oxford University Press
Page : 449 pages
File Size : 53,8 Mb
Release : 2016-01-05
Category : Medical
ISBN : 9780191503603

Get Book

Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton by Roger Smith,Paul Wordsworth Pdf

Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton 2 is a definitive reference providing comprehensive coverage of common polygenic and rare monogenic disorders, emphasizing new advances in bone cell biology and human skeletal disease. With an up-to-date account of common and rare metabolic disorders of the skeleton, including their causes, clinical aspects, and treatment, this book offers the reader clarity in the complex field of the molecular biology of the skeleton. Topics covered include bone biology and investigation, osteoporosis, osteomalacia and rickets, parathyroid bone disease, Paget disease, and the effects of malignancy on the skeleton. Newer metabolic bone disorders are also included, along with chapters on osteogenesis imperfecta, skeletal dysplasias, osteopetrosis and osteosclerosis, Marfan syndrome, Ehlers-Danlos syndrome, fibrous dysplasia, and ectopic mineralisation. Essential for postgraduates and clinicians, this accessible and highly illustrated book provides a clear authoritative account of metabolic bone diseases in their widest sense. Bringing together considerable advances in the field, it discusses molecular causes and personal experiences of all disorders, ensuring a comprehensive and didactic reference. Enriched with over 100 new illustrations and revised chapters to reflect a rapidly developing field, this second edition will be indispensable for those who look after patients with metabolic bone disease, including general physicians, rheumatologists, endocrinologists, and orthopaedic surgeons, along with paediatricians and geneticists. This print edition of The Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Author : Hooshang Taybi,Ralph S. Lachman
Publisher : Mosby Incorporated
Page : 1135 pages
File Size : 49,9 Mb
Release : 1996
Category : Medical
ISBN : 0815187092

Get Book

Radiology of Syndromes, Metabolic Disorders, and Skeletal Dysplasias by Hooshang Taybi,Ralph S. Lachman Pdf

Intended for the practitioner and student, this clinical radiologic reference is one of the most widely used by pediatric radiologists today. This edition features an expanded Gamuts section, which presents differential diagnoses of various clinical and radiologic symptoms and signs. Genetic information on syndromes and disorders is also included.

Author : Edward F. McCarthy,Frank J. Frassica
Publisher : Cambridge University Press
Page : 385 pages
File Size : 46,9 Mb
Release : 2014-11-20
Category : Medical
ISBN : 9781107041233

Get Book

Pathology of Bone and Joint Disorders Print and Online Bundle by Edward F. McCarthy,Frank J. Frassica Pdf

Fully updated new edition covering all aspects of bone and joint diseases in one easily readable volume. Color illustrations throughout.

Author : Maurice M. Reeder
Publisher : Springer Science & Business Media
Page : 998 pages
File Size : 48,7 Mb
Release : 2006-04-18
Category : Medical
ISBN : 9780387216867

Get Book

Reeder and Felson’s Gamuts in Radiology by Maurice M. Reeder Pdf

Gamuts in Radiology is the world's most complete, best known, and most trusted guide to radiologic differential diagnosis. Since 1975, radiologists the world over have used it to ensure that every diagnostic possibility is considered. For the Fourth Edition, Dr. Maurice M. Reeder has assembled an all-new board of Section Editors who have completely revised and updated their respective sections. New features in the fourth edition include: over 250 new gamuts, updates in more than 80 percent of the previous gamuts, an entire new section on obestetrical ultrasound.

Author : Francis H. Glorieux,John M. Pettifor,Harald Jüppner
Publisher : Academic Press
Page : 885 pages
File Size : 40,8 Mb
Release : 2011-09-28
Category : Medical
ISBN : 9780123820402

Get Book

Pediatric Bone by Francis H. Glorieux,John M. Pettifor,Harald Jüppner Pdf

Pediatric osteology, a medical specialty that has come of age, has contributed to the understanding of adult bone diseases as well. This second edition reference updates the 2003 edition with more emphasis on management as well as new and revised contributions. Thirty chapters present basic information regarding bone development, tools and techniques for evaluation (including a new chapter on radiographic imaging), and the specifics of various diseases. The three editors are affiliated as follows: Francis H. Glorieux (McGill U., Canada), John M. Pettifor (Chir Hani Baragwanath Hospital, South Africa), and Harald Juppner (Harvard Medical School, US). Academic Press is an imprint of Elsevier. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com).

Author : Wilfred C. G. Peh
Publisher : Springer
Page : 976 pages
File Size : 45,6 Mb
Release : 2017-08-11
Category : Medical
ISBN : 9783319534961

Get Book

Pitfalls in Musculoskeletal Radiology by Wilfred C. G. Peh Pdf

This superbly illustrated book offers comprehensive and systematic coverage of the pitfalls that may arise during musculoskeletal imaging, whether as a consequence of the imaging technique itself or due to anatomical variants or particular aspects of disease. The first section is devoted to technique-specific artifacts encountered when using different imaging modalities and covers the entire range of advanced methods, including high-resolution ultrasonography, computed tomography, magnetic resonance imaging and positron emission tomography. Advice is provided on correct imaging technique. In the second section, pitfalls in imaging interpretation that may occur during the imaging of trauma to various structures and of the diseases affecting these structures are described. Misleading imaging appearances in such pathologies as inflammatory arthritides, infections, metabolic bone lesions, congenital skeletal dysplasis, tumors and tumor-like conditions are highlighted, and normal variants are also identified. Pitfalls in Musculoskeletal Radiology will be an invaluable source of information for the practicing radiologist, facilitating recognition of pitfalls of all types and avoidance of diagnostic errors and misinterpretations, with their medicolegal implications.

Author : B. J. Cremin,P. Beighton
Publisher : Springer Science & Business Media
Page : 109 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642483073

Get Book

Bone Dysplasias of Infancy by B. J. Cremin,P. Beighton Pdf

The tremendous expansion of medical knowledge during the last few decades, together with the introduction of many new diagnostic techniques, has demanded such a degree of specialisation that no single individual can be conversant with all the information available. More and more emphasis, therefore, has been placed on the importance of teamwork and close collaboration between associated disciplines. The bone dysplasias of infancy represent a classical example of this concept. Only a few years ago these heritable conditions were divided into a relatively small number of entities, for many of which "atypical variants" were accepted. More recent studies have resulted in appreciation and early recognition of a large number of these disorders, thanks to co-operation between paediatricians, radiologists, geneticists and biochemists. Not only maya reasonably accurate prognosis be offered for the affected child in many instances, but, almost of greater value, genetic counselling concerning the chance of subsequent offspring being similarly affected has become available to parents. Most radiologists have little opportunity of becoming familiar with this rapidly widening field of diagnosis, so that the occasional case which may be encountered is likely to engender diagnostic difficulty. This Atlas should facilitate greatly the solution of the problem. It has been prepared by Professor CREMIN, an outstanding paediatric radiologist whose work has been known and admired by me for many years, in close collaboration with his colleague Professor BEIGHTON, a geneticist of great distinction.

Author : Vincent J. Vigorita
Publisher : Lippincott Williams & Wilkins
Page : 872 pages
File Size : 45,9 Mb
Release : 2015-09-21
Category : Medical
ISBN : 9781496326881

Get Book

Orthopaedic Pathology by Vincent J. Vigorita Pdf

Ideal for orthopaedic, pathology, and radiology residents and practitioners, the updated third edition of Orthopaedic Pathology is a comprehensive, practical guide to diagnosing musculoskeletal disorders, offering details on the pathologic and radiologic characteristics of all bone and joint diseases. Highlighted by more than 1,700 high-quality illustrations, it focuses on helping you reach an accurate diagnosis for virtually any orthopaedic disorder you’re likely to encounter, including cysts, arthritis, synovial lesions, fibrous lesions, metastatic cancer, metabolic bone disease such as osteoporosis and Paget’s disease, fractures, osteomyelitis, tumors and tumor-like lesions and developmental bone disorders. A separate section on soft-tissue pathology discusses meniscal injuries, bursa, ligaments, and tendons.