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Author : Barbara R. Cardoso,Cristiane Cominetti,Lucia A. Seale
Publisher : Frontiers Media SA
Page : 141 pages
File Size : 53,5 Mb
Release : 2022-02-22
Category : Medical
ISBN : 9782889744701
Author : Catherine Méplan ,David J. Hughes
Publisher : MDPI
Page : 170 pages
File Size : 41,8 Mb
Release : 2020-12-06
Category : Science
ISBN : 9783039361465
“Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This highlights the importance of personalized nutrition strategies targeted at individuals with increased risk of disease and low selenium intake. The mechanisms by which selenium status, selenoprotein expression, and inherited genetic variations in the selenium pathway interact to affect molecular pathways involved in disease development are explored in human cohorts [2,3,5-7], and in animal [4] and in vitro models [8]. Furthermore, some reports identified novel potential biomarkers of disease risk and prognosis within the selenium pathway that could further our understanding of many chronic diseases [2,3]. Overall, this book broadens our understanding of the role of selenium in chronic diseases, and provides new directions for future preventative approaches.
Author : Catherine Méplan,David J. Hughes
Publisher : Unknown
Page : 170 pages
File Size : 41,6 Mb
Release : 2020
Category : Electronic
ISBN : 3039361473
“Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This highlights the importance of personalized nutrition strategies targeted at individuals with increased risk of disease and low selenium intake. The mechanisms by which selenium status, selenoprotein expression, and inherited genetic variations in the selenium pathway interact to affect molecular pathways involved in disease development are explored in human cohorts [2,3,5-7], and in animal [4] and in vitro models [8]. Furthermore, some reports identified novel potential biomarkers of disease risk and prognosis within the selenium pathway that could further our understanding of many chronic diseases [2,3]. Overall, this book broadens our understanding of the role of selenium in chronic diseases, and provides new directions for future preventative approaches.
Author : Bernhard Michalke
Publisher : Springer
Page : 522 pages
File Size : 47,5 Mb
Release : 2018-10-24
Category : Medical
ISBN : 9783319953908
This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-metabolism--as well as the molecular pathways, physiological roles, and the molecular action of selenium including interaction with other elements and vitamins or as Se-nanoparticles. The reader will receive the newest information regarding redox status and redox regulatory systems, specifically in relation to different glutathione peroxidases and thioredoxin-reductases as well as about cellular bioavailability and cytotoxicity, de-balanced immune response, inflammation or dietary aspects.
Author : Institute of Medicine,Food and Nutrition Board,Standing Committee on the Scientific Evaluation of Dietary Reference Intakes,Subcommittee on Interpretation and Uses of Dietary Reference Intakes,Subcommittee on Upper Reference Levels of Nutrients,Panel on Dietary Antioxidants and Related Compounds
Publisher : National Academies Press
Page : 530 pages
File Size : 44,7 Mb
Release : 2000-08-27
Category : Medical
ISBN : 9780309069496
This volume is the newest release in the authoritative series of quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. Dietary Reference Intakes (DRIs) is the newest framework for an expanded approach developed by U.S. and Canadian scientists. This book discusses in detail the role of vitamin C, vitamin E, selenium, and the carotenoids in human physiology and health. For each nutrient the committee presents what is known about how it functions in the human body, which factors may affect how it works, and how the nutrient may be related to chronic disease. Dietary Reference Intakes provides reference intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for different groups based on age and gender, along with a new reference intake, the Tolerable Upper Intake Level (UL), designed to assist an individual in knowing how much is "too much" of a nutrient.
Author : Dolph L. Hatfield,Ulrich Schweizer,Petra A. Tsuji,Vadim N. Gladyshev
Publisher : Springer
Page : 628 pages
File Size : 42,6 Mb
Release : 2016-09-15
Category : Medical
ISBN : 9783319412832
In the current edition, Selenium: Its Molecular Biology and Role in Human Health expands extensively on the previous editions providing readers with the most significant advances in the rapidly developing selenium field. Evidence from epidemiology and veterinary science supports the essential role of selenium in (human) health, but its split personality in both preventing and supporting cancer and also in promoting insulin resistance has become more clearly defined. The pivotal role of glutathione peroxidase 4 in a new process of programmed cell death, ferroptosis, brings new impetus to the field. Recently defined mutations in selenoprotein and biosynthesis factor genes have been identified in patients, and the resulting disorders further emphasize the significance of selenoproteins in human health. The mechanism of selenoprotein biosynthesis, the functions of selenoproteins, and the roles of dietary selenium have been further elucidated, and new regulatory mechanisms involving selenoproteins discovered. The book, therefore, covers the breadth of current selenium research. With up-to-date chapters written by leaders in their fields, it serves as an invaluable resource for novices as well as specialists.
Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Diet and Health
Publisher : National Academies Press
Page : 765 pages
File Size : 55,6 Mb
Release : 1989-01-01
Category : Medical
ISBN : 9780309039949
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Author : Victor R. Preedy,Vinood B. Patel
Publisher : Springer
Page : 0 pages
File Size : 41,7 Mb
Release : 2019-03-22
Category : Medical
ISBN : 3319553860
This book addresses the causes and effects of nutrient deficiencies along the cell-to-communities continuum. The book is primarily concerned with a lack or deficiency of one or more micro- or macronutrients in connection with malnutrition, under nutrition, and starvation. Embedded within the deficiency states is acute restriction whereby food is withdrawn completely for short periods, as when individuals are adhering to religious requirements or undergoing surgical procedures. Further downstream is the consumption of a fraction of the normal diet, as when individuals are dieting or when there is restriction in the amount or variety of food available. The causes of such reductions in dietary intake are varied and also include the social context of poverty, financial limitations, and famine. Refugees and displaced persons may also be vulnerable to under nutrition or total starvation. Diseases may also impact on the total food consumed, such as when there are physical impediments (intestinal obstruction or dysphagia) or anorexia (induced by organic disease or as a disease process per se, ie, anorexia nervosa). This book, organized as approximately 125 chapters in 17 major sections, covers the variable manifestations of dietary restrictions on cells, whole organs, the individual, and societies.
Author : Dolph L. Hatfield,Marla J. Berry,Vadim N. Gladyshev
Publisher : Springer Science & Business Media
Page : 596 pages
File Size : 51,6 Mb
Release : 2011-11-13
Category : Science
ISBN : 9781461410256
Many health benefits have been attributed to selenium that include preventing various forms of cancer (e.g., colon cancer, prostate cancer, lung cancer and liver cancer), heart disease and other cardiovascular and muscle disorders, inhibiting viral expression, delaying the progression of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV)-positive patients, slowing the aging process, and having roles in mammalian development, including male reproduction and immune function. The purpose of the book is the same as the first two volumes which is to bring an up to date status of current research in the rapidly developing selenium field centered around the health benefits attributed to this element and how this element makes its way into protein.
Author : Raymond F. Burk
Publisher : Unknown
Page : 250 pages
File Size : 40,9 Mb
Release : 1994
Category : Nutrition
ISBN : UOM:39015032835269
Presents research syntheses on a number of important topics in the field of selenium, an element that is important in human health. Deficiency of selenium has been linked to Keshan disease in children, cretinism, cancer, and other diseases. Of interest to basic, nutritional, and medical scientists.
Author : Georgette Lockett
Publisher : Independently Published
Page : 0 pages
File Size : 52,7 Mb
Release : 2023-12-14
Category : Health & Fitness
ISBN : 9798871829783
Embark on an illuminating journey into the world of Selenium, a trace mineral that holds the key to optimal health and well-being. In this comprehensive guide, delve into the depths of this crucial element, uncovering its significance and multifaceted roles. Discover the elemental force behind Selenium's prowess, from its definition and chemical properties to its profound impact on human health. Unravel the intricate tapestry of its functions and benefits, ranging from its antioxidant properties to its indispensable contribution to immune function and thyroid health. But beware, for imbalances lurk at both ends of the spectrum! Learn to navigate the treacherous territories of deficiency and toxicity, understanding their causes, symptoms, and the populations most at risk. Navigate the maze of nutrition, decoding recommended dietary allowances and the delicate balance of supplementation. Grasp the threads connecting Selenium to disease prevention, exploring its potential in safeguarding against chronic illnesses like cancer and supporting cardiovascular health. It's not just about human health - explore the symbiotic relationship between Selenium and agriculture, deciphering its impact on crops and ecosystems. Peer into the future through the lens of research, unveiling the promising therapeutic applications awaiting discovery. But knowledge alone won't suffice; this guide empowers action. Learn how to infuse Selenium into your daily life through dietary habits, supplementation considerations, and holistic lifestyle choices. Are you ready to unlock the secrets of Selenium and embrace a healthier, more balanced life? Seize this guide, chart your course toward well-being, and harness the power of Selenium today.
Author : National Academy of Sciences,Institute of Medicine
Publisher : National Academies Press
Page : 190 pages
File Size : 46,6 Mb
Release : 1992-01-01
Category : Medical
ISBN : 9780309040495
Results from the National Research Council's (NRC) landmark study Diet and health are readily accessible to nonscientists in this friendly, easy-to-read guide. Readers will find the heart of the book in the first chapter: the Food and Nutrition Board's nine-point dietary plan to reduce the risk of diet-related chronic illness. The nine points are presented as sensible guidelines that are easy to follow on a daily basis, without complicated measuring or calculatingâ€"and without sacrificing favorite foods. Eat for Life gives practical recommendations on foods to eat and in a "how-to" section provides tips on shopping (how to read food labels), cooking (how to turn a high-fat dish into a low-fat one), and eating out (how to read a menu with nutrition in mind). The volume explains what protein, fiber, cholesterol, and fats are and what foods contain them, and tells readers how to reduce their risk of chronic disease by modifying the types of food they eat. Each chronic disease is clearly defined, with information provided on its prevalence in the United States. Written for everyone concerned about how they can influence their health by what they eat, Eat for Life offers potentially lifesaving information in an understandable and persuasive way. Alternative Selection, Quality Paperback Book Club
Author : Marco Malavolta,Eugenio Mocchegiani
Publisher : Springer
Page : 328 pages
File Size : 45,8 Mb
Release : 2018-11-13
Category : Medical
ISBN : 9783030037420
This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
Author : Fan Huang,Chang Li,Yu Zhao,Zhanzhan Zhang
Publisher : Frontiers Media SA
Page : 153 pages
File Size : 42,7 Mb
Release : 2023-10-30
Category : Science
ISBN : 9782832537466
Author : Raymond F. Burk
Publisher : Springer
Page : 221 pages
File Size : 42,7 Mb
Release : 2011-10-04
Category : Science
ISBN : 1461225930
Selenium plays a fascinating and still poorly understood role in the function of living cells and therefore in human health. Starting with investigations over 60 years ago into its role as a toxic agent in livestock disease, selenium studies have progressed rapidly with the application of tools from immunology and molecular biology. Selenium is now known to be important in human and animal nutrition, has been discovered as a structural component of so-called selenoproteins, and may play a number of physiological roles, ranging from cancer protection to hormone metabolism. Selenium in Biology and Human Health presents research syntheses on a range of topics involving selenium, written by specialists from around the world. It will be of interest to cell biologists and physiologists, nutritional scientists, and animal health researchers.