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Author : Gordon L. Fain
Publisher : Unknown
Page : 294 pages
File Size : 48,8 Mb
Release : 2019-10
Category : Electronic
ISBN : 9780198835028
Provides a comprehensive and up-to-date review of transduction in various sensory modalities.
Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
Page : 502 pages
File Size : 53,5 Mb
Release : 2006-09-29
Category : Medical
ISBN : 9781420005844
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Author : Antonio Borsellino,Luigi Cervetto,Vincent Torre
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468458411
Present knowledge of the mechanisms underlying any single sensory modality is so massive as to discourage effort directed towards completeness. The idea underlying the structure of this volume on "Sensory transduction" was to select just a few topics of general interest, which are currently being investigated and for which a reasonably clear picture is now available. During the last five years there has been a revolution in the way sensory physi ologists think about transduction, and a series of exciting advances have been made in understanding the basic processes of photo transduction, chemotransduction and mechan otransduction. It is clear that in many cases the fundamental processes by which nature attains optimization of performance are similar, and that they have much in common with more general processes of signal recognition by living structures. The molecular events underlying the detection of photons by visual cells, the recognition of a given molecule by a chemoreceptor, or the level of a hormone in the extracellular fluid by a target cell, are all very similar, and involve the activation of a sequence of events leading to a secon d messenger. The 20 papers that form the present volume cover various topics in the field of sensory transduction. They originate from the lectures, seminars and discussions which made up the XVIII Course of the International School of Biophysics held in Erice, 9th - 19th June 1988.
Author : Frank Zufall,Steven D. Munger
Publisher : Academic Press
Page : 430 pages
File Size : 52,8 Mb
Release : 2016-02-18
Category : Science
ISBN : 9780128017869
Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University’s Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals. Provides a comprehensive overview for all chemosensory transduction mechanisms Valuable for academics focused on sensory biology, neurobiology, and chemosensory transduction, as well as industry researchers in new flavor, fragrance, and food testing Edited by leading experts in the field of olfactory transduction Focuses on mammals, but lower vertebrates and invertebrate model systems are also included
Author : Gordon L. Fain
Publisher : Oxford University Press
Page : 304 pages
File Size : 49,6 Mb
Release : 2019-10-17
Category : Science
ISBN : 9780192571977
How are sights and sounds and smells converted into electrical signals in a form that can be interpreted by the nervous system? Although this process, called sensory transduction, began to be understood only relatively recently, so much progress has been made that it is now possible to say at least in outline (but in most cases in remarkable detail) how transduction occurs for all of the major sense organs of the body. Since the first edition was published in 2003, many new experiments have radically changed some of our previously-held views.This new edition fulfils the book's original aims, both as an accessible textbook and a general introduction to the senses, by bringing the contents fully up to date with the new information acquired over the last 15 years. In so doing, it continues to provide a comprehensive survey of one of the greatest achievements of modern biology and neuroscience - the unravelling of the mechanism of sensation. Sensory Transduction is written for advanced undergraduates, graduate students, and researchers in neurophysiology and sensory neuroscience. It is also of relevance and use to a broader audience of neuro, evolutionary, integrative, and comparative biologists.
Author : Stephan Frings,Jonathan Bradley
Publisher : John Wiley & Sons
Page : 321 pages
File Size : 44,5 Mb
Release : 2006-03-06
Category : Science
ISBN : 9783527604975
This is the first book to provide a molecular level explanation of how the senses work, linking molecular biology with sensory physiology to deduce the molecular mechanism of a key step in sensory signal generation. The editors have assembled expert authors from all fields of sensory physiology for an authoritative overview of the mechanisms of sensory signal transduction in both animals and plants. They systematically cover phototransduction, chemosensory transduction, mechanotransduction, temperature and pain perception, as well as specialized receptors for electrical and magnetic signals. Required reading for biologists, physiologists and medical researchers with an interest in sensory physiology.
Author : Giuliano Colombetti,Francesco Lenci
Publisher : Springer Science & Business Media
Page : 391 pages
File Size : 45,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461326755
The main purpose of this book is to unify approaches and ideas in the field of aneural sensory transduction. This field has recently come to the attention of several research groups in various disciplines, and their number seems to be growing. Unfortunately, because of the diverse scientific backgrounds of the researchers in the field, the apparent heterogeneity of experimental techniques (i. e. , behavioral response analysis, sophisticated biochemical and genetic manipulations, conventional and pulsed laser spectroscopy) and theoretical approaches may be discouraging, for both the experienced worker and the new comer. Actually, this heterogeneity is more apparent than real, and unifying concepts, approaches, and ideas already exist, particularly with respect to all the questions concerning the role of membranes and their properties (such as ion permeability, electric potentials, and active transport) in the various steps of sensory perception and transduction processes. It is currently accepted that most, if not all, the fundamental facts in molecular sensory physiology of aneural organisms, be they chemosensory, photosensory, or geosensory, can ultimately be understood in terms of a few basic ideas. Each chapter of this book emphasizes and clarifies the role of mem brane properties and phenomena in the particular sensory response examined. Of course, in some cases, this task has been rather complex because of the limited amount of experimental data clearly supporting a membrane-based model of sensory transduction.
Author : Carla Mucignat-Caretta
Publisher : CRC Press
Page : 614 pages
File Size : 54,5 Mb
Release : 2014-02-14
Category : Medical
ISBN : 9781466553415
Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism—ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their presence to members of the same species and to regulate interactions aimed at establishing and regulating social and reproductive bonds. In the last two decades, scientists have developed a greater understanding of the neural processing of these chemical signals. Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans. The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones. An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.
Author : Rodolfo Madrid,Juan Bacigalupo
Publisher : Springer
Page : 234 pages
File Size : 55,8 Mb
Release : 2015-08-24
Category : Medical
ISBN : 9783319187051
TRP channels play a key role in sensory physiology and have been the focus of intensive investigation in recent years. The proposed book will be a comprehensive, detailed overview of the ways in which TRP channels are involved in a wide variety of sensory modalities. Authors will explore the involvement of TRP channels in photo transduction (sight), chemotransduction (taste and odor), mechanotransduction (touch and hearing), thermo transduction (the sensation of temperature) and pain perception. Furthermore, the book will include some grounding chapters such as one on the history of TRP channel research, one on the biophysical characteristics of the proteins and one on trafficking and post-translational regulation.
Author : Francesco Lenci
Publisher : Springer Science & Business Media
Page : 421 pages
File Size : 55,7 Mb
Release : 2013-03-09
Category : Science
ISBN : 9781461591641
This book collects all the lectures presented during the NATO Advanced Study Institute on "Photoreception and Sensory Transduction in Aneura1 Organisms," held in Villa Le Pianore (Versi1ia, Italy), September 3-14, 1979. In order to publish the lectures in the shortest possible time, we had to make the decision not to include the free communications, the informal seminars, and the panel discussions, notwithstanding their very high scientific level and interest. Only the final panel discussion has been summarized by Prof. W. Haupt (whose effort we gratefully acknowledge), because it gives a comprehensive view of the state of the art in this field. The ASI was intended to be a high-level course, characterized by an interdisciplinary approach to the problem of photoreception and photosensory physiology in aneural organisms, bringing together scientists from different fields and specializations. We hope that these characteristics are reflected in the content of the book, which is meant to be both an advanced textbook for researchers and students entering the field and a critical overview of the problems of photosensory transduction in aneura1 organisms. The topics pre sented range from a phenomenological description of the different photomotile responses in various microorganisms to a discussion of the molecular processes involved in the primary events of photo reception as well as in the subsequent steps of the transduction chain.
Author : Lewis C. Cantley,Tony Hunter,Richard Sever,Jeremy Thorner
Publisher : Unknown
Page : 452 pages
File Size : 49,8 Mb
Release : 2014-05-31
Category : Science
ISBN : 0879699019
"This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. It first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function"--
Author : Bastien D. Gomperts,Ijsbrand M. Kramer,Peter E.R. Tatham
Publisher : Gulf Professional Publishing
Page : 444 pages
File Size : 42,7 Mb
Release : 2003-10-15
Category : Medical
ISBN : 0122896327
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Author : Friedrich Marks,Ursula Klingmüller,Karin Müller-Decker
Publisher : Garland Science
Page : 982 pages
File Size : 47,5 Mb
Release : 2017-05-17
Category : Medical
ISBN : 9781351677219
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Author : Bozzano G Luisa
Publisher : Academic Press
Page : 480 pages
File Size : 45,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323139120
An explosion of information has occurred over the past few years in the field of signal transduction. As information form prokaryotes and eukaryotes has accumulated, it has become evident that diverse sensory systems share common mechanistic themes. This volume reviews our the current knowledge of molecular mechanisms for sensory transduction in a variety of microbial systems, as well as elegant work done in nematodes and Drosophila. Signal Transduction is intended for both researchers studying microbial systems and investigators and students of signal transduction in more complex organisms, who can learn from the paradigms and mechanisms conserved between prokaryotes and eukaryotes.
Author : L. Jaenicke
Publisher : Springer
Page : 644 pages
File Size : 42,5 Mb
Release : 2011-11-11
Category : Medical
ISBN : 3642660142
This volume contains the Proceedings of the 25th Mosbach Colloquium, the general theme of which is the Biochemistry of Sensory Functions. It was intended, continuing the silver-tradition of these Colloquia, to provide the uninitiated biochemist with an insight into the current status of a line of research in Molecular Biology which, more than many other fields in Biochemistry, has maintained its contacts with and respect for Physiology. The speakers were asked to attempt to outline their topic sufficiently to define the fundamentals and to build up upon this basis the more sophisticated details of their own studies. It is for the reader to evaluate how well both organizer and participants 1 have attained this end • These Proceedings not only mirror the hubs around which several groups of scientists wheel but may also serve as a source of literature references and for the advanced student as an introduction to this highly up-to-date branch of Biochemistry, although no index is provided as the table of con tents is considered sufficient to locate most of the s,
