Membranes And Sensory Transduction

Author : Giuliano Colombetti,Francesco Lenci
Publisher : Springer Science & Business Media
Page : 391 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461326755

Get Book

Membranes and Sensory Transduction by Giuliano Colombetti,Francesco Lenci Pdf

The main purpose of this book is to unify approaches and ideas in the field of aneural sensory transduction. This field has recently come to the attention of several research groups in various disciplines, and their number seems to be growing. Unfortunately, because of the diverse scientific backgrounds of the researchers in the field, the apparent heterogeneity of experimental techniques (i. e. , behavioral response analysis, sophisticated biochemical and genetic manipulations, conventional and pulsed laser spectroscopy) and theoretical approaches may be discouraging, for both the experienced worker and the new comer. Actually, this heterogeneity is more apparent than real, and unifying concepts, approaches, and ideas already exist, particularly with respect to all the questions concerning the role of membranes and their properties (such as ion permeability, electric potentials, and active transport) in the various steps of sensory perception and transduction processes. It is currently accepted that most, if not all, the fundamental facts in molecular sensory physiology of aneural organisms, be they chemosensory, photosensory, or geosensory, can ultimately be understood in terms of a few basic ideas. Each chapter of this book emphasizes and clarifies the role of mem brane properties and phenomena in the particular sensory response examined. Of course, in some cases, this task has been rather complex because of the limited amount of experimental data clearly supporting a membrane-based model of sensory transduction.

Author : Giuliano Colombetti,Francesco Lenci
Publisher : Springer
Page : 380 pages
File Size : 47,5 Mb
Release : 2012-01-30
Category : Science
ISBN : 1461326761

Get Book

Membranes and Sensory Transduction by Giuliano Colombetti,Francesco Lenci Pdf

The main purpose of this book is to unify approaches and ideas in the field of aneural sensory transduction. This field has recently come to the attention of several research groups in various disciplines, and their number seems to be growing. Unfortunately, because of the diverse scientific backgrounds of the researchers in the field, the apparent heterogeneity of experimental techniques (i. e. , behavioral response analysis, sophisticated biochemical and genetic manipulations, conventional and pulsed laser spectroscopy) and theoretical approaches may be discouraging, for both the experienced worker and the new comer. Actually, this heterogeneity is more apparent than real, and unifying concepts, approaches, and ideas already exist, particularly with respect to all the questions concerning the role of membranes and their properties (such as ion permeability, electric potentials, and active transport) in the various steps of sensory perception and transduction processes. It is currently accepted that most, if not all, the fundamental facts in molecular sensory physiology of aneural organisms, be they chemosensory, photosensory, or geosensory, can ultimately be understood in terms of a few basic ideas. Each chapter of this book emphasizes and clarifies the role of mem brane properties and phenomena in the particular sensory response examined. Of course, in some cases, this task has been rather complex because of the limited amount of experimental data clearly supporting a membrane-based model of sensory transduction.

Author : Gordon L. Fain
Publisher : Unknown
Page : 294 pages
File Size : 41,8 Mb
Release : 2019-10
Category : Electronic
ISBN : 9780198835028

Get Book

Sensory Transduction by Gordon L. Fain Pdf

Provides a comprehensive and up-to-date review of transduction in various sensory modalities.

Author : Antonio Borsellino,Luigi Cervetto,Vincent Torre
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468458411

Get Book

Sensory Transduction by Antonio Borsellino,Luigi Cervetto,Vincent Torre Pdf

Present knowledge of the mechanisms underlying any single sensory modality is so massive as to discourage effort directed towards completeness. The idea underlying the structure of this volume on "Sensory transduction" was to select just a few topics of general interest, which are currently being investigated and for which a reasonably clear picture is now available. During the last five years there has been a revolution in the way sensory physi ologists think about transduction, and a series of exciting advances have been made in understanding the basic processes of photo transduction, chemotransduction and mechan otransduction. It is clear that in many cases the fundamental processes by which nature attains optimization of performance are similar, and that they have much in common with more general processes of signal recognition by living structures. The molecular events underlying the detection of photons by visual cells, the recognition of a given molecule by a chemoreceptor, or the level of a hormone in the extracellular fluid by a target cell, are all very similar, and involve the activation of a sequence of events leading to a secon d messenger. The 20 papers that form the present volume cover various topics in the field of sensory transduction. They originate from the lectures, seminars and discussions which made up the XVIII Course of the International School of Biophysics held in Erice, 9th - 19th June 1988.

Author : Krishna C. Persaud,Santiago Marco,Agustin Gutierrez-Galvez
Publisher : CRC Press
Page : 237 pages
File Size : 42,9 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439871720

Get Book

Neuromorphic Olfaction by Krishna C. Persaud,Santiago Marco,Agustin Gutierrez-Galvez Pdf

Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p

Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
Page : 502 pages
File Size : 55,5 Mb
Release : 2006-09-29
Category : Medical
ISBN : 9781420005844

Get Book

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by Wolfgang B. Liedtke, MD, PH.D. Pdf

Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,5 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

Get Book

Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Lindsay Biga,Devon Quick,Sierra Dawson,Amy Harwell,Robin Hopkins,Joel Kaufmann,Mike LeMaster,Philip Matern,Katie Morrison-Graham,Jon Runyeon
Publisher : Unknown
Page : 128 pages
File Size : 48,8 Mb
Release : 2019-09-26
Category : Electronic
ISBN : 1955101159

Get Book

Anatomy & Physiology by Lindsay Biga,Devon Quick,Sierra Dawson,Amy Harwell,Robin Hopkins,Joel Kaufmann,Mike LeMaster,Philip Matern,Katie Morrison-Graham,Jon Runyeon Pdf

A version of the OpenStax text

Author : Peter J. Quinn
Publisher : Springer Science & Business Media
Page : 502 pages
File Size : 41,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475758061

Get Book

Membrane Dynamics and Domains by Peter J. Quinn Pdf

The fluid-mosaic model of membrane structure formulated by Singer and Nicolson in the early 1970s has proven to be a durable concept in terms of the principles governing the organization of the constituent lipids and proteins. During the past 30 or so years a great deal of information has accumulated on the composition of various cell membranes and how this is related to the dif ferent functions that membranes perform. Nevertheless, the task of explaining particular functions at the molecular level has been hampered by lack of struc tural detail at the atomic level. The reason for this is primarily the difficulty of crystallizing membrane proteins which require strategies that differ from those used to crystallize soluble proteins. The unique exception is bacteriorhodopsin of the purple membrane of Halobacterium halobium which is interpolated into a membrane that is neither fluid nor in a mosaic configuration. To date only 50 or so membrane proteins have been characterised to atomic resolution by diffraction methods, in contrast to the vast data accumulated on soluble proteins. Another factor that has been difficult to explain is the reason why the lipid compliment of membranes is often extremely complex. Many hundreds of different molecular species of lipid can be identified in some membranes. Remarkably, the particular composition of each membrane appears to be main tained within relatively narrow limits and its identity distinguished from other morphologically-distinct membranes.

Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Page : 618 pages
File Size : 44,5 Mb
Release : 2018-01-07
Category : Science
ISBN : 9888407457

Get Book

Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Author : Robert J. Person,Roger Thies
Publisher : Springer Science & Business Media
Page : 271 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468403428

Get Book

Physiology by Robert J. Person,Roger Thies Pdf

This review covers the major systems of human physiology. These Notes are not exhaustive and assume that students have completed a course in human physiology and wish to refresh their memory in preparing for an examination. Students are encouraged to refer to a comprehensive textbook or to monographs while using this review. This book is a revised version of a review book used by our medical students for over ten years. Coverage of various topics in physiology is comparable to the percentage of questions on those topics in recent National Board, Part I examinations. Review questions follow every few pages of text in order to monitor your understanding of the just preceding material. Multiple choice questions are mainly of the two conventional types; "single best answer" questions and "multiple correct answer" questions. "Single co~ct answer" questions have lettered alternatives (Le. , A to E); "multiple correct answer" questions have numbered alternatives (Le. , 1, 2, 3 and 4). The latter questions are answered as follows: Answer A if 1, 2 and 3 are correct Answer B if 1 and 3 are correct Answer C if 2 and 4 are correct Answer D if 4 only is correct Answer E if all are correct National Board Examinations also use matching questions, and matching with four choices (Le. , Situation 1, Situation 2, Both 1 and 2, Neither 1 or 2). Review questions are numbered consecutively within each of the seven chapters.

Author : Meir Shinitzky
Publisher : Wiley-Blackwell
Page : 344 pages
File Size : 52,5 Mb
Release : 1993
Category : Science
ISBN : UOM:39015026923592

Get Book

Biomembranes, Signal Transduction Across Membranes by Meir Shinitzky Pdf

Biomembranes Signal Transduction Across Membranes Edited by Meir Shinitzky An up-to-date review of basic research on biomembranes. In this volume, foremost experts in the field consider the most important aspects of signal transduction across biological membranes: General Mechanistic Patterns of Signal Transduction Receptors for Neurotransmitters and Peptide Hormones G Proteins in Signal Transduction Membrane-associated Protein Kinases and Phosphatases Phospholipases in Signal Transduction The volume is an excellent supplement to "Biomembranes -- Physical Aspects" and "Biomembranes -- Structural and Functional Aspects," also edited by Meir Shinitzky. These three books together provide a comprehensive ground for understanding complex physiological processes. Meir Shinitzky, Ph.D., is Professor of Biophysics in the Department of Membrane Research and Biophysics. The Weizman Institute of Science, Rehovot, Israel. Since 1971, his research has focused on various aspects of membrane structure and dynamics.

Author : A.E. Evangelopoulos,J.P. Changeux,L. Packer,T.G. Sotiroudis,K.W.A. Wirtz
Publisher : Springer
Page : 387 pages
File Size : 52,8 Mb
Release : 2011-12-06
Category : Science
ISBN : 3642742025

Get Book

Receptors, Membrane Transport and Signal Transduction by A.E. Evangelopoulos,J.P. Changeux,L. Packer,T.G. Sotiroudis,K.W.A. Wirtz Pdf

A NATO Advanced study Institute on "Receptors, Membrane Trans port and Signal Transduction", was held on the Island of Spet sai, Greece, from August 16-27, 1988, in order to consider re cent developments in membrane receptor research, membrane trans port and signal transduction mechanisms. These topics were put in the larger context of current knowledge on the structure and function of membranes; connections between different fields of research were established by in-depth dis cussions of energy transduction and transport mechanisms. The general principles of regulation by signal transduction and protein phosphorylation/dephosphorylation were presented in the context of specific cellular processes. Discussions included al so the role of protein tyrosine kinases which are structurally related to oncogene products and, therefore, implicated in va rious aspects of cell development and transformation. This book presents the content of the major lectures and a se lection of the most relevant posters presented during the course of the Institute. The book is intended to make the proceedings of the Institute accessible to a larger audience and to offer a comprehensive account of those topics on receptors, membrane transport and signal transduction that were discussed extensive ly during the course of the Institute. February 1989 The Editors CONTENTS I. G-PROTEINS, ADENYLATE CYCLASE AND PROTEIN PHOSPHORYLATION Selective regulation of G proteins by Cell surface receptors ......... .

Author : F. Javier Alvarez-Leefmans,Eric Delpire
Publisher : Academic Press
Page : 630 pages
File Size : 42,6 Mb
Release : 2009-08-22
Category : Medical
ISBN : 9780080922034

Get Book

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System by F. Javier Alvarez-Leefmans,Eric Delpire Pdf

The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases. The first comprehensive book on the structure, molecular biology, cell physiology, and role in diseases of chloride transporters / channels in the nervous system in almost 20 years Chloride is the most abundant free anion in animal cells. THis book summarizes and integrates for the first time the important research of the past two decades that has shown that Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control The first book that systematically discusses the result of disruption of Cl- homeostasis in neurons which underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation Spanning topics from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases Involves all of the leading researchers in the field Includes an extensive introductory section that covers basic thermodynamic and kinetics aspects of Cl- transport, as well as current methods for studying Cl- regulation, spanning from fluorescent dyes in single cells to knock-out models to make the book available for a growing population of graduate students and postdocs entering the field

Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 47,5 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808

Get Book

Anatomy and Physiology by J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young Pdf