Septic Shock

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Sepsis Management in Resource-limited Settings

Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz
Sepsis Management in Resource limited Settings Book PDF

Author : Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz
Publisher : Springer
Page : 216 pages
File Size : 46,7 Mb
Release : 2019-02-08
Category : Medical
ISBN : 9783030031435

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Sepsis Management in Resource-limited Settings by Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz Pdf

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Septic Shock

Benedict Graver
Septic Shock Book PDF

Author : Benedict Graver
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 55,6 Mb
Release : 2015
Category : Septic shock
ISBN : 1634639162

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Septic Shock by Benedict Graver Pdf

In a 2013 Healthcare Cost and Utilization Project Statistical Brief by the US Agency for Healthcare Research and Quality, septicemia was ranked as the number one most expensive national inpatient hospital cost. This ranking comes in spite of substantial advances in the clinical management of sepsis over the past fifteen years. While adherence with internationally established sepsis management protocols have demonstrated reduction in mortality and hospital/ICU length of stay, compliance with these protocols remains poor. This book discusses risk factors, management and prognosis of septic shock in individuals.

Essentials of Shock Management

Gil Joon Suh
Essentials of Shock Management Book PDF

Author : Gil Joon Suh
Publisher : Springer
Page : 147 pages
File Size : 42,9 Mb
Release : 2018-11-30
Category : Medical
ISBN : 9789811054068

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Essentials of Shock Management by Gil Joon Suh Pdf

This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of shock – septic, hemorrhagic, cardiogenic, anaphylactic, and obstructive – at all stages from initial response through to ICU admission. As well as management, the coverage encompasses pathophysiology, clinical presentation, diagnosis, and emerging trends. A further key feature is the use of a scenario-based approach to present a series of cases based on real-life experiences. Here, a narrative style and Q&A form are employed to vividly convey scenarios that may be encountered in clinical practice and to elucidate decision making in complex circumstances. When readers experience difficulty in answering the questions, the earlier sections can be consulted to identify the correct response. This book will be of great value for all health care professionals. In particular, it will be very helpful for novice or inexperienced practitioners in emergency medicine, critical care medicine, and traumatology.

Clinical Management of Shock

Stanislaw P. Stawicki,Mamta Swaroop
Clinical Management of Shock Book PDF

Author : Stanislaw P. Stawicki,Mamta Swaroop
Publisher : BoD – Books on Demand
Page : 210 pages
File Size : 44,5 Mb
Release : 2020-06-24
Category : Medical
ISBN : 9781838811709

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Clinical Management of Shock by Stanislaw P. Stawicki,Mamta Swaroop Pdf

Shock is a physiological state of war! From a healthcare provider perspective, the word “shock” is associated with a mixed array of feelings, including dread, well-founded fear, and deep respect. The physiological state of shock is well recognized for the associated destructive consequences, and its successful management requires prompt identification, immediate action, and sustained effort by all members of the healthcare team. This mindset of advanced preparation and constant readiness constitutes the foundation of the modern approach toward shock – early detection and prompt treatment for optimal outcomes. Despite the heterogeneity of “shock” as a clinico-pathological entity, there are some common threads that permeate all forms and manifestations of shock, with apparent increase in observed commonalities in the more advanced (and often irreversible) stages of the systemic syndrome. When faced with shock, the body and its systems do their best to compensate for the maldistribution of oxygen and nutrients. This is known as the so-called compensated shock. Beyond that, the body loses its ability to adjust any further, thus descending into “uncompensated shock,” with a refractory state characterized by vasoplegia and irreversible cardiovascular failure. As the reader journeys through the chapters of the book, he or she will read about various biomarkers and endpoints of resuscitation, explore different types of shock (e.g., septic, hemorrhagic, anaphylactic) and learn about some of the less often discussed topics such as neurogenic and spinal shock, as well as the amniotic fluid embolism. Our goals were to keep things clinically relevant and practically oriented, thus enabling the reader to apply the newly acquired knowledge in their everyday clinical routines. As the reader progresses through the book, we hope to help stimulate further discourse and innovative thinking about the topic. In this context, it is critical that basic, translational, and clinical research on shock continues to advance. Only through ongoing scientific progress can we help improve outcomes for patients with both rare and common forms of shock.

Pathophysiology of Shock, Sepsis, and Organ Failure

Günther Schlag,Heinz Redl
Pathophysiology of Shock Sepsis and Organ Failure Book PDF

Author : Günther Schlag,Heinz Redl
Publisher : Springer Science & Business Media
Page : 1180 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642767364

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Pathophysiology of Shock, Sepsis, and Organ Failure by Günther Schlag,Heinz Redl Pdf

In this book current knowledge of the pathophysiology of shock, sepsis and multi organ failure is presented. The rapid progress which has been made and the results achieved in intensive care medicine are based on sound basic research, which is duly reflected in these chapters. Multiorgan failure is the foremost cause of postoperative and posttraumatic death and many complex mechanisms are involved. Only with a good foundation of basic research can abnormalities in the physiological, biochemical, and morphological course of shock be recognized and the necessary conclusions for treatment drawn. Therapy must proceed from profound knowledge of the multi variant physiological events in order to influence shock, sepsis and organ failure. Although numerous possibilities for therapy have arisen from pharmaceutical research in recent years, they are beyond the scope of this book and are not discussed here. To gain a better understanding of the pathophysiological events it was necessary to examine and to describe different models that simulate and reproduce these events. Here we describe the causative agents (shock) and the consequences (sepsis, organ failure) in two main sections, divided on the basis of their pathophysiology.

Septic Shock

Jean-François Dhainaut,Lambertus G. Thijs,Gilbert R. Park
Septic Shock Book PDF

Author : Jean-François Dhainaut,Lambertus G. Thijs,Gilbert R. Park
Publisher : Bailliere Tindall Limited
Page : 608 pages
File Size : 50,6 Mb
Release : 2000
Category : Medical
ISBN : UOM:39015050173940

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Septic Shock by Jean-François Dhainaut,Lambertus G. Thijs,Gilbert R. Park Pdf

A current, authoritative guide to the clinical management of the critically ill septic shock patient. Discusses the benefits and limitations of alternative management strategies. Identifies key clinical problems to be addressed, and assigns the correct priority to each problem in a step-by-step manner. Checklists and algorithms are provided as appropriate.

Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases

Gerald L. Mandell,John Eugene Bennett
Mandell Douglas and Bennett s Principles and Practice of Infectious Diseases Book PDF

Author : Gerald L. Mandell,John Eugene Bennett
Publisher : Unknown
Page : 1489 pages
File Size : 49,5 Mb
Release : 1995
Category : Communicable diseases
ISBN : 0443089353

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Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases by Gerald L. Mandell,John Eugene Bennett Pdf

Discusses infectious diseases by major clinical syndrome, specific etiologic organism, and by host characteristics for patients who are compromised.

Septic Shock

George H. Sakorafas,Adelais G. Tsiotou
Septic Shock Book PDF

Author : George H. Sakorafas,Adelais G. Tsiotou
Publisher : Nova Publishers
Page : 128 pages
File Size : 44,8 Mb
Release : 2005
Category : Septic shock
ISBN : 159454168X

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Septic Shock by George H. Sakorafas,Adelais G. Tsiotou Pdf

Sepsis is one of the most frequent complications in the surgical patient and one of the leading causes of mortality in intensive care units. During the past two decades, a great deal has been learned about surgical bacteriology, antibiotic prophylaxis, supportive management, and the host response to microbial invasion. Sepsis can be caused by infection with gram-negative bacteria, gram-positive bacteria, fungi (and particularly Candida), or viruses. Sepsis may also occur in the absence of detectable bacterial invasion, and in these cases, microbial toxins, particularly gram-negative bacterial endotoxin (lipopolysaccharide, LPS), and endogenous cytokine production have been implicated as initiators and mediators. Although activation of the immune system during microbial invasion is generally protective, septic shock develops in a significant number of patients as a consequence of a poorly regulated immune response to the offending organism. Sepsis can be presented with a spectrum of severity. Septic shock represents the most severe form of host response to infection. The aim of this monograph is to summarise the currently available data regarding epidemiology, pathogenesis, and optimal management of septic shock, with a particular emphasis on the role of source control in sepsis. Emerging therapies for septic shock are also discussed.

The Sepsis Text

Jean-Louis Vincent,Jean Carlet,Steven M. Opal
The Sepsis Text Book PDF

Author : Jean-Louis Vincent,Jean Carlet,Steven M. Opal
Publisher : Springer Science & Business Media
Page : 848 pages
File Size : 45,9 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9780306476648

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The Sepsis Text by Jean-Louis Vincent,Jean Carlet,Steven M. Opal Pdf

This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the culmination of decades of basic and applied research by innovative researchers and clinical investigators worldwide. The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology; monitoring systems; general support; microbial aspects; complications; and anti-sepsis therapies.

Oxford Textbook of Critical Care

Webb
Oxford Textbook of Critical Care Book PDF

Author : Webb
Publisher : Oxford University Press
Page : 1961 pages
File Size : 52,6 Mb
Release : 2020-01-10
Category : Medical
ISBN : 9780198855439

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Oxford Textbook of Critical Care by Webb Pdf

Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

Oxford Handbook of Acute Medicine

Punit S. Ramrakha,Kevin P. Moore
Oxford Handbook of Acute Medicine Book PDF

Author : Punit S. Ramrakha,Kevin P. Moore
Publisher : Oxford University Press, USA
Page : 1011 pages
File Size : 43,9 Mb
Release : 2004
Category : Medical
ISBN : 9780198520726

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Oxford Handbook of Acute Medicine by Punit S. Ramrakha,Kevin P. Moore Pdf

This practical guide to the management of emergency situations in everyday clinical practice contains details on how to treat acute medical emergencies and how to provide treatment for the patient while awaiting specialist help.

An Introduction to Clinical Emergency Medicine

S. V. Mahadevan,Gus M. Garmel
An Introduction to Clinical Emergency Medicine Book PDF

Author : S. V. Mahadevan,Gus M. Garmel
Publisher : Cambridge University Press
Page : 911 pages
File Size : 52,5 Mb
Release : 2012-04-10
Category : Medical
ISBN : 9780521747769

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An Introduction to Clinical Emergency Medicine by S. V. Mahadevan,Gus M. Garmel Pdf

Fully-updated edition of this award-winning textbook, arranged by presenting complaints with full-color images throughout. For students, residents, and emergency physicians.

Hemodynamic Monitoring

Michael R. Pinsky,Jean-Louis Teboul,Jean-Louis Vincent
Hemodynamic Monitoring Book PDF

Author : Michael R. Pinsky,Jean-Louis Teboul,Jean-Louis Vincent
Publisher : Springer
Page : 476 pages
File Size : 48,7 Mb
Release : 2019-02-21
Category : Medical
ISBN : 9783319692692

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Hemodynamic Monitoring by Michael R. Pinsky,Jean-Louis Teboul,Jean-Louis Vincent Pdf

This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.

Septic Shock Methods and Protocols

Thomas J. Evans
Septic Shock Methods and Protocols Book PDF

Author : Thomas J. Evans
Publisher : Springer Science & Business Media
Page : 206 pages
File Size : 43,7 Mb
Release : 2008-02-01
Category : Medical
ISBN : 9781592592166

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Septic Shock Methods and Protocols by Thomas J. Evans Pdf

Septic shock remains a serious medical condition with high mortality. Despite many advances in intensive care medicine and antibiotic devel- ment, this has not changed appreciably in the last 20 years. Frustratingly, over the same period of time, enormous advances have been made in understa- ing the underlying pathogenic mechanisms of this condition. This has resulted in the development of several novel therapies for septic shock, which, despite excellent theoretical grounds for their efficacy, have failed in altering mort- ity attributable to sepsis. The reasons for these failures are multiple, but it is clear that further research is required aimed at increasing our understanding of the basic pat- physiological processes that occur following infection. Research into septic shock draws upon a number of different disciplines, ranging from molecular and cellular biology to physiological measurements on whole animals. Septic Shock Methods and Protocols is an attempt to draw together into one volume a number of protocols that are of use in the investigation of the mechanisms of septic shock. I have divided the book into five sections. The first deals with endotoxin, the lipopolysaccharide component of the Gram-negative cell m- brane that can mimic many of the features of septic shock. Gram-positive organisms are found increasingly as causes of septic shock, and several - pects of toxins produced from these bacteria are considered in the second s- tion.

Nephrology and Public Health Worldwide

G.B. Silva Junior,A. Ferreiro Fuentes,M. Nangaku,G. Remuzzi,C. Ronco
Nephrology and Public Health Worldwide Book PDF

Author : G.B. Silva Junior,A. Ferreiro Fuentes,M. Nangaku,G. Remuzzi,C. Ronco
Publisher : Karger Medical and Scientific Publishers
Page : 369 pages
File Size : 43,5 Mb
Release : 2021-11-02
Category : Medical
ISBN : 9783318069372

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Nephrology and Public Health Worldwide by G.B. Silva Junior,A. Ferreiro Fuentes,M. Nangaku,G. Remuzzi,C. Ronco Pdf

Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the desirable equity worldwide, the nephrology community needs to discuss this public health issue and take part in decisions for elaboration of public health policies with more justice and equity. This book brings together key current public health problems that affect kidney function and illuminates them in contributions by an international group of nephrologists and general practitioners. The chapters review current knowledge and provide guidelines to manage these conditions and decrease the disease burden. At the end, developments in the digital era and their application to kidney disease treatment are synthesized, and a broader outlook on the future of nephrology is given. Ultimately, the publication aims to gather nephrology and public health expertise from researchers from all over the world, providing a broad vision of issues that must be discussed and overcome to guarantee a better treatment for patients with kidney diseases in the world today.