Sex And Gender Differences In Cardiovascular Renal Metabolic Physiology And Pathophysiology

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Sex and Gender Differences in Cardiovascular-Renal Diseases and Hypertension

Jane Reckelhoff
Sex and Gender Differences in Cardiovascular Renal Diseases and Hypertension Book PDF

Author : Jane Reckelhoff
Publisher : Biota Publishing
Page : 99 pages
File Size : 50,7 Mb
Release : 2014-11-01
Category : Medical
ISBN : 9781615045792

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Sex and Gender Differences in Cardiovascular-Renal Diseases and Hypertension by Jane Reckelhoff Pdf

Many of the mechanisms responsible for cardiovascular disease and hypertension are well known, and gender is an independent risk factor in many cohorts. How gender contributes to cardiovascular disease has not been completely elucidated. Even in normotensive populations, blood pressure is higher in men than women, although why this occurs is unclear. While both men and women suffer from high incidences of cardiovascular disease, women are typically protected against cardiovascular disease until after menopause, so that on average they are about 10 years older than men when these diseases develop, making aging a confounding problem contributing to increased morbidity. Because hypertension is one of the leading causes of cardiovascular disease in both men and women, this review will focus on hypertension, and the mechanisms that have been found to play a role in mediating blood pressure control and how they differ in men and women.

Gender Differences in the Pathogenesis and Management of Heart Disease

Jawahar L. Mehta,Jean McSweeney
Gender Differences in the Pathogenesis and Management of Heart Disease Book PDF

Author : Jawahar L. Mehta,Jean McSweeney
Publisher : Springer
Page : 361 pages
File Size : 45,9 Mb
Release : 2018-03-02
Category : Medical
ISBN : 9783319711355

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Gender Differences in the Pathogenesis and Management of Heart Disease by Jawahar L. Mehta,Jean McSweeney Pdf

This book reviews all aspects of the diagnosis and management of heart disease in women, covering areas such as gender differences in metabolic syndrome, hypertension and atherogenesis. Gender differences in cardiovascular diseases are widespread, but while gender medicine takes into account the effects of sex and gender on the health of women and men, traditionally, women have been underrepresented in cardiovascular clinical trials, in management of different cardiac diseases and drug use. Gender Differences in the Pathogenesis and Management of Heart Disease deals with the gender-specific differences in cardiac physiology and diseases and brings into perspective the critical significance of gender in management of cardiovascular disease presentations and management. As such it is of enormous use to all clinical staff who manage women with cardiovascular disease.

Sex Differences in Physiology

Gretchen Neigh,Megan Mitzelfelt
Sex Differences in Physiology Book PDF

Author : Gretchen Neigh,Megan Mitzelfelt
Publisher : Academic Press
Page : 236 pages
File Size : 47,9 Mb
Release : 2016-05-10
Category : Medical
ISBN : 9780128026083

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Sex Differences in Physiology by Gretchen Neigh,Megan Mitzelfelt Pdf

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Sex Differences in Cardiovascular Physiology and Pathophysiology

Babbette LaMarca, Ph.D.,Barbara T. Alexander, PhD, FAHA, FAPS
Sex Differences in Cardiovascular Physiology and Pathophysiology Book PDF

Author : Babbette LaMarca, Ph.D.,Barbara T. Alexander, PhD, FAHA, FAPS
Publisher : Academic Press
Page : 392 pages
File Size : 49,8 Mb
Release : 2019-06-15
Category : Medical
ISBN : 9780128131978

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Sex Differences in Cardiovascular Physiology and Pathophysiology by Babbette LaMarca, Ph.D.,Barbara T. Alexander, PhD, FAHA, FAPS Pdf

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Sex Differences in Cardiovascular Physiology and Pathophysiology

Babbette LaMarca,Barbara T. Alexander
Sex Differences in Cardiovascular Physiology and Pathophysiology Book PDF

Author : Babbette LaMarca,Barbara T. Alexander
Publisher : Academic Press
Page : 392 pages
File Size : 54,5 Mb
Release : 2019-04-09
Category : Medical
ISBN : 9780128131985

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Sex Differences in Cardiovascular Physiology and Pathophysiology by Babbette LaMarca,Barbara T. Alexander Pdf

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Metabolic Cardiomyopathy

H. Böhles,A. C. Sewell
Metabolic Cardiomyopathy Book PDF

Author : H. Böhles,A. C. Sewell
Publisher : CRC Press
Page : 188 pages
File Size : 54,8 Mb
Release : 2004
Category : Cardiomyopathy
ISBN : 3887631048

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Metabolic Cardiomyopathy by H. Böhles,A. C. Sewell Pdf

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Exploring the Biological Contributions to Human Health

Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Exploring the Biological Contributions to Human Health Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publisher : National Academies Press
Page : 288 pages
File Size : 40,9 Mb
Release : 2001-07-02
Category : Medical
ISBN : 0309132975

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Exploring the Biological Contributions to Human Health by Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences Pdf

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Sex and Gender Aspects in Clinical Medicine

Sabine Oertelt-Prigione,Vera Regitz-Zagrosek
Sex and Gender Aspects in Clinical Medicine Book PDF

Author : Sabine Oertelt-Prigione,Vera Regitz-Zagrosek
Publisher : Springer Science & Business Media
Page : 204 pages
File Size : 51,6 Mb
Release : 2011-11-15
Category : Medical
ISBN : 0857298321

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Sex and Gender Aspects in Clinical Medicine by Sabine Oertelt-Prigione,Vera Regitz-Zagrosek Pdf

This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.

Management of Cardiovascular Disease in Women

Hanna Z. Mieszczanska,Gladys P. Velarde
Management of Cardiovascular Disease in Women Book PDF

Author : Hanna Z. Mieszczanska,Gladys P. Velarde
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 41,5 Mb
Release : 2014-03-24
Category : Medical
ISBN : 9781447155171

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Management of Cardiovascular Disease in Women by Hanna Z. Mieszczanska,Gladys P. Velarde Pdf

Cardiovascular disease is the leading cause of death in women in the US, with more women dying from heart disease than men. Women may have different presentation from men and often need a different approach to diagnosis and treatment. There are also unique topics of management of heart disease in women, including issues during pregnancy, lactation, and menopause. Many different health care providers, as well as cardiologists are involved in treating these patients. A manual reviewing diagnosis and treatment of cardiac disease in women would help providers without specific cardiology training to deliver care with greater efficiency. A practical and comprehensive guide geared towards these providers would be a highly practical and valuable resource that would be utilized in everyday practice in offices that include urban clinics, general medicine offices, obstetrics and gynecology offices, as well as in the surgical subspecialties. This book will be a highly practical resource that can be directly applied to the issues that arise in everyday practice. There is no available book on the market that focuses on a broader approach to cardiac disease in women or focuses on non-cardiology providers (and their trainees) who have the need to know more about treatment of cardiovascular disease in women.​

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Franck Mauvais-Jarvis
Sex and Gender Factors Affecting Metabolic Homeostasis Diabetes and Obesity Book PDF

Author : Franck Mauvais-Jarvis
Publisher : Springer
Page : 627 pages
File Size : 49,8 Mb
Release : 2017-12-08
Category : Medical
ISBN : 9783319701783

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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity by Franck Mauvais-Jarvis Pdf

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Sex and Gender Differences in Pharmacology

Vera Regitz-Zagrosek
Sex and Gender Differences in Pharmacology Book PDF

Author : Vera Regitz-Zagrosek
Publisher : Springer Science & Business Media
Page : 599 pages
File Size : 51,8 Mb
Release : 2012-10-02
Category : Medical
ISBN : 9783642307263

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Sex and Gender Differences in Pharmacology by Vera Regitz-Zagrosek Pdf

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

H.Gerhard Vogel,Jochen Maas,Alexander Gebauer
Drug Discovery and Evaluation Methods in Clinical Pharmacology Book PDF

Author : H.Gerhard Vogel,Jochen Maas,Alexander Gebauer
Publisher : Springer Science & Business Media
Page : 576 pages
File Size : 55,6 Mb
Release : 2010-12-15
Category : Medical
ISBN : 9783540898900

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Drug Discovery and Evaluation: Methods in Clinical Pharmacology by H.Gerhard Vogel,Jochen Maas,Alexander Gebauer Pdf

Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

Caffeine for the Sustainment of Mental Task Performance

Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research
Caffeine for the Sustainment of Mental Task Performance Book PDF

Author : Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research
Publisher : National Academies Press
Page : 172 pages
File Size : 51,6 Mb
Release : 2002-01-07
Category : Medical
ISBN : 9780309082587

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Caffeine for the Sustainment of Mental Task Performance by Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research Pdf

This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.

Principles of Gender-Specific Medicine

Marianne J. Legato
Principles of Gender Specific Medicine Book PDF

Author : Marianne J. Legato
Publisher : Academic Press
Page : 792 pages
File Size : 55,7 Mb
Release : 2017-05-15
Category : Medical
ISBN : 9780128035429

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Principles of Gender-Specific Medicine by Marianne J. Legato Pdf

The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols

Cardiac Drugs

Kanu Chatterjee,Eric J Topol
Cardiac Drugs Book PDF

Author : Kanu Chatterjee,Eric J Topol
Publisher : JAYPEE BROTHERS PUBLISHERS
Page : 529 pages
File Size : 54,6 Mb
Release : 2013-12-15
Category : Cardiovascular agents
ISBN : 9789350907795

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Cardiac Drugs by Kanu Chatterjee,Eric J Topol Pdf

Doody Rating : 3 stars : Cardiac drugs resource endows with the latest advances in cardiovascular pharmacology. Written by experts in cardiology from world renowned institutes, equipped with global view, signifying the best possible combination of clinical and research expertise in cardiovascular pharmacology. This is a comprehensive drug resource which provides up-to-date information on one of the most rapidly changing areas of medicine. Easy to follow, providing practical advice on how to manage cardiac diseases with a focus on hands-on therapeutic guidance for the clinicians. Text talks abo.