Sex Differences In Cardiovascular Physiology And Pathophysiology

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Sex Differences in Cardiovascular Physiology and Pathophysiology

Babbette LaMarca,Barbara T. Alexander
Sex Differences in Cardiovascular Physiology and Pathophysiology Book PDF

Author : Babbette LaMarca,Barbara T. Alexander
Publisher : Academic Press
Page : 392 pages
File Size : 52,8 Mb
Release : 2019-04-09
Category : Medical
ISBN : 9780128131985

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Sex Differences in Cardiovascular Physiology and Pathophysiology by Babbette LaMarca,Barbara T. Alexander Pdf

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Gender Differences in the Pathogenesis and Management of Heart Disease

Jawahar L. Mehta,Jean McSweeney
Gender Differences in the Pathogenesis and Management of Heart Disease Book PDF

Author : Jawahar L. Mehta,Jean McSweeney
Publisher : Springer
Page : 361 pages
File Size : 44,6 Mb
Release : 2018-03-02
Category : Medical
ISBN : 9783319711355

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Gender Differences in the Pathogenesis and Management of Heart Disease by Jawahar L. Mehta,Jean McSweeney Pdf

This book reviews all aspects of the diagnosis and management of heart disease in women, covering areas such as gender differences in metabolic syndrome, hypertension and atherogenesis. Gender differences in cardiovascular diseases are widespread, but while gender medicine takes into account the effects of sex and gender on the health of women and men, traditionally, women have been underrepresented in cardiovascular clinical trials, in management of different cardiac diseases and drug use. Gender Differences in the Pathogenesis and Management of Heart Disease deals with the gender-specific differences in cardiac physiology and diseases and brings into perspective the critical significance of gender in management of cardiovascular disease presentations and management. As such it is of enormous use to all clinical staff who manage women with cardiovascular disease.

Sex Differences in Physiology

Gretchen Neigh,Megan Mitzelfelt
Sex Differences in Physiology Book PDF

Author : Gretchen Neigh,Megan Mitzelfelt
Publisher : Academic Press
Page : 236 pages
File Size : 50,7 Mb
Release : 2016-05-10
Category : Medical
ISBN : 9780128026083

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Sex Differences in Physiology by Gretchen Neigh,Megan Mitzelfelt Pdf

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Sex Differences in Heart Disease

Bohuslav Ostadal,Naranjan S. Dhalla
Sex Differences in Heart Disease Book PDF

Author : Bohuslav Ostadal,Naranjan S. Dhalla
Publisher : Springer Nature
Page : 284 pages
File Size : 54,6 Mb
Release : 2020-11-15
Category : Science
ISBN : 9783030586775

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Sex Differences in Heart Disease by Bohuslav Ostadal,Naranjan S. Dhalla Pdf

Cardiovascular diseases are the leading cause of mortality in men and women. Unfortunately, women have traditionally been excluded from clinical trials, and female animals have been used less or sex was not reported in basic research studies. Until recently, consideration of both sexes was not required in clinical and preclinical studies focusing on cardiovascular diseases. However, the number of clinical and experimental papers dealing with sex differences and heart disease significantly increases during the last years. This trend is obviously the result of at least two facts: the number of examples of different behavior of the male and female heart under physiological and pathological conditions is steadily increasing and there were controversial reports on the beneficial and adverse effect of hormonal replacement therapy. Detailed molecular and cellular mechanisms of these differences are still unknown but one is clear already today: sex differences are so important that they should be considered by the selection of optimum diagnostic and therapeutic procedures in clinical practice. The book presents 16 manuscripts on sex differences of heart disease, as developed by several investigators; the volume is organized in four parts. Part I, dealing with sex differences in cardiac ischemic injury, includes 5 chapters on experimental aspects of cardiac ischemia/reperfusion injury, the role of testosterone, and clinical aspects of ischemic heart disease. Part II is devoted to sex differences in heart failure and includes four chapters. Discussion in this part of the book is centered around the sex differences in heart failure due to volume overload. Part III of this volume includes four papers on risk factors of cardiovascular diseases, namely hypertension and obesity, and, finally, three chapters in part IV deal with sex differences of cardiac mitochondria under different pathological conditions. We believe this book will be very useful for cardiovascular scientists, graduate students, postdoctoral fellows and other health professionals.

Sex and Gender Differences in Cardiovascular-Renal-Metabolic Physiology and Pathophysiology

Jane Reckelhoff,Licy Yanes Cardozo,Noha Shawky
Sex and Gender Differences in Cardiovascular Renal Metabolic Physiology and Pathophysiology Book PDF

Author : Jane Reckelhoff,Licy Yanes Cardozo,Noha Shawky
Publisher : Academic Press
Page : 0 pages
File Size : 53,5 Mb
Release : 2024-09-01
Category : Science
ISBN : 0443222665

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Sex and Gender Differences in Cardiovascular-Renal-Metabolic Physiology and Pathophysiology by Jane Reckelhoff,Licy Yanes Cardozo,Noha Shawky Pdf

Sex and Gender Differences in Cardiovascular-Renal-Metabolic Physiology and Pathophysiology: Sex, Gender and Function provides a fundamental overview on sex and gender differences in all aspects of physiology. The book shares information on sex and gender differences in a variety of topics in a single comprehensive volume. This book, published as part of the Fundamentals of Physiology series in association with the International Union of Physiological Sciences acts as a primer of information scientists can build upon with their own research in sex and gender-based research.

Sex-Specific Analysis of Cardiovascular Function

Peter L. M. Kerkhof,Virginia M. Miller
Sex Specific Analysis of Cardiovascular Function Book PDF

Author : Peter L. M. Kerkhof,Virginia M. Miller
Publisher : Springer
Page : 725 pages
File Size : 53,6 Mb
Release : 2018-07-26
Category : Medical
ISBN : 9783319779324

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Sex-Specific Analysis of Cardiovascular Function by Peter L. M. Kerkhof,Virginia M. Miller Pdf

This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.

Sex and Gender Differences in Cardiovascular-Renal Diseases and Hypertension

Jane Reckelhoff
Sex and Gender Differences in Cardiovascular Renal Diseases and Hypertension Book PDF

Author : Jane Reckelhoff
Publisher : Biota Publishing
Page : 99 pages
File Size : 43,8 Mb
Release : 2014-11-01
Category : Medical
ISBN : 9781615045792

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Sex and Gender Differences in Cardiovascular-Renal Diseases and Hypertension by Jane Reckelhoff Pdf

Many of the mechanisms responsible for cardiovascular disease and hypertension are well known, and gender is an independent risk factor in many cohorts. How gender contributes to cardiovascular disease has not been completely elucidated. Even in normotensive populations, blood pressure is higher in men than women, although why this occurs is unclear. While both men and women suffer from high incidences of cardiovascular disease, women are typically protected against cardiovascular disease until after menopause, so that on average they are about 10 years older than men when these diseases develop, making aging a confounding problem contributing to increased morbidity. Because hypertension is one of the leading causes of cardiovascular disease in both men and women, this review will focus on hypertension, and the mechanisms that have been found to play a role in mediating blood pressure control and how they differ in men and women.

Sex differences in Cardiac Diseases

Niti R. Aggarwal,Malissa J. Wood
Sex differences in Cardiac Diseases Book PDF

Author : Niti R. Aggarwal,Malissa J. Wood
Publisher : Elsevier
Page : 720 pages
File Size : 51,9 Mb
Release : 2021-02-09
Category : Medical
ISBN : 9780128193693

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Sex differences in Cardiac Diseases by Niti R. Aggarwal,Malissa J. Wood Pdf

Significant biological differences exist between men and women that contribute to sex-specific differences in cardiovascular disease (CVD) risk factors, pathophysiology, presentation, response to therapy, and prognosis. It is essential for clinicians to be cognizant of these sex-specific differences in order to reduce the disparity in diagnosis and management of cardiovascular diseases in both genders. Sex Differences in Cardiac Disease provides a timely review of the contemporary data on these sex-specific differences in pathophysiology, clinical presentation, diagnostic evaluation, and management of cardiovascular diseases that fills a void for clinicians in practice and training. With contributions from renowned experts in the field and guideline writers, the text provides a state-of-the-art review of each topic encompassing the full spectrum of CVD in men and women. Sex-specific guideline-based recommendations are highlighted when available. Tailored to meet the needs of the busy clinicians and researchers, this text provides concise practical data to care for men and women at risk for or with CVD. The book serves as an essential resource for researchers, cardiologists, obstetricians, gynecologists, internists, family practitioners, nurse practitioners and physician assistants, and respective trainees who treat men and women with CVD. Provides a comprehensive state-of-the-art text written by internationally renowned experts in the field of CVD disease, serving as an indispensable resource for clinicians and researchers Enables the reader to understand the sexual dimorphism in the pathophysiology, diagnosis, management, and outcomes of the full spectrum of cardiovascular issues including ischemic heart disease, valvular disorders, arrhythmias, and heart failure Provides a concise evidence-based practical review of medical topics, with key points and eye-catching visual infographics to meet the needs of the busy clinicians, policy makers and researchers.

Exploring the Biological Contributions to Human Health

Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Exploring the Biological Contributions to Human Health Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publisher : National Academies Press
Page : 288 pages
File Size : 55,7 Mb
Release : 2001-07-02
Category : Medical
ISBN : 0309132975

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Exploring the Biological Contributions to Human Health by Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences Pdf

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Principles of Sex-based Differences in Physiology

Virginia L. Miller,Virginia M. Miller,Meredith Hay
Principles of Sex based Differences in Physiology Book PDF

Author : Virginia L. Miller,Virginia M. Miller,Meredith Hay
Publisher : Gulf Professional Publishing
Page : 356 pages
File Size : 47,6 Mb
Release : 2004
Category : Electronic books
ISBN : 044451497X

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Principles of Sex-based Differences in Physiology by Virginia L. Miller,Virginia M. Miller,Meredith Hay Pdf

Differences in physiology between men and women extend far beyond differences in reproductive functions. Medical literature abounds in descriptions of differences in prevalence, symptoms and severity of diseases between men and women including heart attack, rheumatic diseases, gastrointestinal disease and osteoporosis. Much of the information is descriptive rather than mechanistic and scattered throughout a variety of books, review articles and original papers. This book provides a single source that summarizes current basic mechanisms of gene/hormone interactions and their subsequent impact on physiological functions. It is an ideal source material to be used in training the next generation of physician/scientists who will develop a more individualized approach to prevention, diagnosis and therapeutic medical practice.

Management of Cardiovascular Disease in Women

Hanna Z. Mieszczanska,Gladys P. Velarde
Management of Cardiovascular Disease in Women Book PDF

Author : Hanna Z. Mieszczanska,Gladys P. Velarde
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 49,5 Mb
Release : 2014-03-24
Category : Medical
ISBN : 9781447155171

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Management of Cardiovascular Disease in Women by Hanna Z. Mieszczanska,Gladys P. Velarde Pdf

Cardiovascular disease is the leading cause of death in women in the US, with more women dying from heart disease than men. Women may have different presentation from men and often need a different approach to diagnosis and treatment. There are also unique topics of management of heart disease in women, including issues during pregnancy, lactation, and menopause. Many different health care providers, as well as cardiologists are involved in treating these patients. A manual reviewing diagnosis and treatment of cardiac disease in women would help providers without specific cardiology training to deliver care with greater efficiency. A practical and comprehensive guide geared towards these providers would be a highly practical and valuable resource that would be utilized in everyday practice in offices that include urban clinics, general medicine offices, obstetrics and gynecology offices, as well as in the surgical subspecialties. This book will be a highly practical resource that can be directly applied to the issues that arise in everyday practice. There is no available book on the market that focuses on a broader approach to cardiac disease in women or focuses on non-cardiology providers (and their trainees) who have the need to know more about treatment of cardiovascular disease in women.​

Sex and Cardiac Electrophysiology

Marek Malik
Sex and Cardiac Electrophysiology Book PDF

Author : Marek Malik
Publisher : Academic Press
Page : 986 pages
File Size : 46,9 Mb
Release : 2020-07-11
Category : Science
ISBN : 9780128177297

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Sex and Cardiac Electrophysiology by Marek Malik Pdf

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients Provides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure

Principles of Gender-Specific Medicine

Marianne Legato J
Principles of Gender Specific Medicine Book PDF

Author : Marianne Legato J
Publisher : Academic Press
Page : 797 pages
File Size : 43,8 Mb
Release : 2009-10-29
Category : Science
ISBN : 9780080921501

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Principles of Gender-Specific Medicine by Marianne Legato J Pdf

The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men as well conditions that predominantly occur in women. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. The Second Edition of Principles of Gender-Specific Medicine focuses on the essentials of gender-specific medicine and the current study of sex and gender differences in human physiology and pathophysiology. New section editors, new chapter authors, and new chapters have been added to reflect the most up-to-date clinical research and practice. Offers insight into how the gender-specific risks of one organ system’s disease affects the health of other organ systems Outlines the sex-specific differences of normal anatomy and physiology Illustrates the gender-specific features and quantifies "gender" and "sex" as risk factors across all major diseases Qualifies and analyzes the results of new drug therapies designed with gender-specific differences in mind: ex, hormone therapy in men and women for the prevention and treatment of cardiovascular disease All chapters progress translationally from the basic science to the clinical applications of gender-specific therapies, drugs, or treatments Sections on drug metabolism, aging, and meta-analysis of data incorporated into all disease-specific chapters

Sex and Gender Aspects in Clinical Medicine

Sabine Oertelt-Prigione,Vera Regitz-Zagrosek
Sex and Gender Aspects in Clinical Medicine Book PDF

Author : Sabine Oertelt-Prigione,Vera Regitz-Zagrosek
Publisher : Springer Science & Business Media
Page : 204 pages
File Size : 42,8 Mb
Release : 2011-11-15
Category : Medical
ISBN : 0857298321

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Sex and Gender Aspects in Clinical Medicine by Sabine Oertelt-Prigione,Vera Regitz-Zagrosek Pdf

This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Franck Mauvais-Jarvis
Sex and Gender Factors Affecting Metabolic Homeostasis Diabetes and Obesity Book PDF

Author : Franck Mauvais-Jarvis
Publisher : Springer
Page : 627 pages
File Size : 40,8 Mb
Release : 2017-12-08
Category : Medical
ISBN : 9783319701783

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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity by Franck Mauvais-Jarvis Pdf

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.