Sex Differences In Cardiac Diseases

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Sex Differences in Heart Disease

Bohuslav Ostadal,Naranjan S. Dhalla
Sex Differences in Heart Disease Book PDF

Author : Bohuslav Ostadal,Naranjan S. Dhalla
Publisher : Springer Nature
Page : 284 pages
File Size : 52,8 Mb
Release : 2020-11-15
Category : Science
ISBN : 9783030586775

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Sex Differences in Heart Disease by Bohuslav Ostadal,Naranjan S. Dhalla Pdf

Cardiovascular diseases are the leading cause of mortality in men and women. Unfortunately, women have traditionally been excluded from clinical trials, and female animals have been used less or sex was not reported in basic research studies. Until recently, consideration of both sexes was not required in clinical and preclinical studies focusing on cardiovascular diseases. However, the number of clinical and experimental papers dealing with sex differences and heart disease significantly increases during the last years. This trend is obviously the result of at least two facts: the number of examples of different behavior of the male and female heart under physiological and pathological conditions is steadily increasing and there were controversial reports on the beneficial and adverse effect of hormonal replacement therapy. Detailed molecular and cellular mechanisms of these differences are still unknown but one is clear already today: sex differences are so important that they should be considered by the selection of optimum diagnostic and therapeutic procedures in clinical practice. The book presents 16 manuscripts on sex differences of heart disease, as developed by several investigators; the volume is organized in four parts. Part I, dealing with sex differences in cardiac ischemic injury, includes 5 chapters on experimental aspects of cardiac ischemia/reperfusion injury, the role of testosterone, and clinical aspects of ischemic heart disease. Part II is devoted to sex differences in heart failure and includes four chapters. Discussion in this part of the book is centered around the sex differences in heart failure due to volume overload. Part III of this volume includes four papers on risk factors of cardiovascular diseases, namely hypertension and obesity, and, finally, three chapters in part IV deal with sex differences of cardiac mitochondria under different pathological conditions. We believe this book will be very useful for cardiovascular scientists, graduate students, postdoctoral fellows and other health professionals.

Sex Differences in Cardiovascular Physiology and Pathophysiology

Babbette LaMarca, Ph.D.,Barbara T. Alexander, PhD, FAHA, FAPS
Sex Differences in Cardiovascular Physiology and Pathophysiology Book PDF

Author : Babbette LaMarca, Ph.D.,Barbara T. Alexander, PhD, FAHA, FAPS
Publisher : Academic Press
Page : 392 pages
File Size : 44,7 Mb
Release : 2019-06-15
Category : Medical
ISBN : 9780128131978

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Sex Differences in Cardiovascular Physiology and Pathophysiology by Babbette LaMarca, Ph.D.,Barbara T. Alexander, PhD, FAHA, FAPS Pdf

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Sex differences in Cardiac Diseases

Niti R. Aggarwal,Malissa J. Wood
Sex differences in Cardiac Diseases Book PDF

Author : Niti R. Aggarwal,Malissa J. Wood
Publisher : Elsevier
Page : 722 pages
File Size : 41,8 Mb
Release : 2021-01-29
Category : Science
ISBN : 9780128193709

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Sex differences in Cardiac Diseases by Niti R. Aggarwal,Malissa J. Wood Pdf

Significant biological differences exist between men and women that contribute to sex-specific differences in cardiovascular disease (CVD) risk factors, pathophysiology, presentation, response to therapy, and prognosis. It is essential for clinicians to be cognizant of these sex-specific differences in order to reduce the disparity in diagnosis and management of cardiovascular diseases in both genders.Sex Differences in Cardiac Disease provides a timely review of the contemporary data on these sex-specific differences in pathophysiology, clinical presentation, diagnostic evaluation, and management of cardiovascular diseases that fills a void for clinicians in practice and training. With contributions from renowned experts in the field and guideline writers, the text provides a state-of-the-art review of each topic encompassing the full spectrum of CVD in men and women. Sex-specific guideline-based recommendations are highlighted when available. Tailored to meet the needs of the busy clinicians and researchers, this text provides concise practical data to care for men and women at risk for or with CVD. The book serves as an essential resource for researchers, cardiologists, obstetricians, gynecologists, internists, family practitioners, nurse practitioners and physician assistants, and respective trainees who treat men and women with CVD. Provides a comprehensive state-of-the-art text written by internationally renowned experts in the field of CVD disease, serving as an indispensable resource for clinicians and researchers Enables the reader to understand the sexual dimorphism in the pathophysiology, diagnosis, management, and outcomes of the full spectrum of cardiovascular issues including ischemic heart disease, valvular disorders, arrhythmias, and heart failure Provides a concise evidence-based practical review of medical topics, with key points and eye-catching visual infographics to meet the needs of the busy clinicians, policy makers and researchers

Gender Differences in the Pathogenesis and Management of Heart Disease

Jawahar L. Mehta,Jean McSweeney
Gender Differences in the Pathogenesis and Management of Heart Disease Book PDF

Author : Jawahar L. Mehta,Jean McSweeney
Publisher : Springer
Page : 361 pages
File Size : 50,8 Mb
Release : 2018-03-02
Category : Medical
ISBN : 9783319711355

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Gender Differences in the Pathogenesis and Management of Heart Disease by Jawahar L. Mehta,Jean McSweeney Pdf

This book reviews all aspects of the diagnosis and management of heart disease in women, covering areas such as gender differences in metabolic syndrome, hypertension and atherogenesis. Gender differences in cardiovascular diseases are widespread, but while gender medicine takes into account the effects of sex and gender on the health of women and men, traditionally, women have been underrepresented in cardiovascular clinical trials, in management of different cardiac diseases and drug use. Gender Differences in the Pathogenesis and Management of Heart Disease deals with the gender-specific differences in cardiac physiology and diseases and brings into perspective the critical significance of gender in management of cardiovascular disease presentations and management. As such it is of enormous use to all clinical staff who manage women with cardiovascular disease.

Metabolic Cardiomyopathy

H. Böhles,A. C. Sewell
Metabolic Cardiomyopathy Book PDF

Author : H. Böhles,A. C. Sewell
Publisher : CRC Press
Page : 188 pages
File Size : 48,6 Mb
Release : 2004
Category : Cardiomyopathy
ISBN : 3887631048

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Metabolic Cardiomyopathy by H. Böhles,A. C. Sewell Pdf

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Sex-Specific Analysis of Cardiovascular Function

Peter L. M. Kerkhof,Virginia M. Miller
Sex Specific Analysis of Cardiovascular Function Book PDF

Author : Peter L. M. Kerkhof,Virginia M. Miller
Publisher : Springer
Page : 725 pages
File Size : 42,7 Mb
Release : 2018-07-26
Category : Medical
ISBN : 9783319779324

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Sex-Specific Analysis of Cardiovascular Function by Peter L. M. Kerkhof,Virginia M. Miller Pdf

This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.

Sex and Cardiac Electrophysiology

Marek Malik
Sex and Cardiac Electrophysiology Book PDF

Author : Marek Malik
Publisher : Academic Press
Page : 986 pages
File Size : 49,7 Mb
Release : 2020-07-11
Category : Science
ISBN : 9780128177297

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Sex and Cardiac Electrophysiology by Marek Malik Pdf

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients Provides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure

Exploring the Biological Contributions to Human Health

Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Exploring the Biological Contributions to Human Health Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publisher : National Academies Press
Page : 288 pages
File Size : 50,5 Mb
Release : 2001-07-02
Category : Medical
ISBN : 0309132975

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Exploring the Biological Contributions to Human Health by Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences Pdf

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Management of Cardiovascular Disease in Women

Hanna Z. Mieszczanska,Gladys P. Velarde
Management of Cardiovascular Disease in Women Book PDF

Author : Hanna Z. Mieszczanska,Gladys P. Velarde
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 40,7 Mb
Release : 2014-03-24
Category : Medical
ISBN : 9781447155171

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Management of Cardiovascular Disease in Women by Hanna Z. Mieszczanska,Gladys P. Velarde Pdf

Cardiovascular disease is the leading cause of death in women in the US, with more women dying from heart disease than men. Women may have different presentation from men and often need a different approach to diagnosis and treatment. There are also unique topics of management of heart disease in women, including issues during pregnancy, lactation, and menopause. Many different health care providers, as well as cardiologists are involved in treating these patients. A manual reviewing diagnosis and treatment of cardiac disease in women would help providers without specific cardiology training to deliver care with greater efficiency. A practical and comprehensive guide geared towards these providers would be a highly practical and valuable resource that would be utilized in everyday practice in offices that include urban clinics, general medicine offices, obstetrics and gynecology offices, as well as in the surgical subspecialties. This book will be a highly practical resource that can be directly applied to the issues that arise in everyday practice. There is no available book on the market that focuses on a broader approach to cardiac disease in women or focuses on non-cardiology providers (and their trainees) who have the need to know more about treatment of cardiovascular disease in women.​

Sex Differences in Physiology

Gretchen Neigh,Megan Mitzelfelt
Sex Differences in Physiology Book PDF

Author : Gretchen Neigh,Megan Mitzelfelt
Publisher : Academic Press
Page : 236 pages
File Size : 48,8 Mb
Release : 2016-05-10
Category : Medical
ISBN : 9780128026083

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Sex Differences in Physiology by Gretchen Neigh,Megan Mitzelfelt Pdf

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Coronary Microvascular Dysfunction

Filippo Crea,Gaetano A. Lanza,Paolo G. Camici
Coronary Microvascular Dysfunction Book PDF

Author : Filippo Crea,Gaetano A. Lanza,Paolo G. Camici
Publisher : Springer Science & Business Media
Page : 257 pages
File Size : 42,9 Mb
Release : 2013-08-15
Category : Medical
ISBN : 9788847053670

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Coronary Microvascular Dysfunction by Filippo Crea,Gaetano A. Lanza,Paolo G. Camici Pdf

In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

Sex Differences in Cardiovascular Physiology and Pathophysiology

Babbette LaMarca,Barbara T. Alexander
Sex Differences in Cardiovascular Physiology and Pathophysiology Book PDF

Author : Babbette LaMarca,Barbara T. Alexander
Publisher : Academic Press
Page : 392 pages
File Size : 45,5 Mb
Release : 2019-04-09
Category : Medical
ISBN : 9780128131985

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Sex Differences in Cardiovascular Physiology and Pathophysiology by Babbette LaMarca,Barbara T. Alexander Pdf

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Brain and Heart Dynamics

Stefano Govoni,Pierluigi Politi,Emilio Vanoli
Brain and Heart Dynamics Book PDF

Author : Stefano Govoni,Pierluigi Politi,Emilio Vanoli
Publisher : Springer
Page : 0 pages
File Size : 43,5 Mb
Release : 2020-07-31
Category : Medical
ISBN : 3030280071

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Brain and Heart Dynamics by Stefano Govoni,Pierluigi Politi,Emilio Vanoli Pdf

This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects. It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

Manual of Gynecardiology

Angela H. E. M. Maas,C. Noel Bairey Merz
Manual of Gynecardiology Book PDF

Author : Angela H. E. M. Maas,C. Noel Bairey Merz
Publisher : Unknown
Page : 251 pages
File Size : 55,6 Mb
Release : 2017
Category : Cardiology
ISBN : 3319549618

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Manual of Gynecardiology by Angela H. E. M. Maas,C. Noel Bairey Merz Pdf

This book provides a much-needed, internationally oriented text, focusing on specific aspects of heart disease in women. Despite the large amount of information available, there is still considerable confusion regarding female patients. As such, the book highlights the health events that occur during aging in women and that may influence the future CVD risk. For instance, pregnancy-related disorders are important predictors for CVD risk in women, and inflammatory diseases like rheumatic, thyroid disorders etc, which also interfere with CVD risk, are also more common in women. Adopting a multidisciplinary approach, including gynecology and endocrinology, it offers separate chapters on female-specific manifestations of ischemic heart disease, such as Tako Tsubo CMP and spontaneous coronary artery dissections. The book also discusses the effects and side effects of important medications. The chapters are clearly formatted, making it easy for readers to find subjects of interest.

Global Health Risks

World Health Organization
Global Health Risks Book PDF

Author : World Health Organization
Publisher : World Health Organization
Page : 71 pages
File Size : 54,9 Mb
Release : 2009-10-28
Category : Business & Economics
ISBN : 9789241563871

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Global Health Risks by World Health Organization Pdf

This publication is a comprehensive assessment of leading risks to global health. It provides detailed global and regional estimates of premature mortality, disability and loss of health attributable to 24 global risk factors.--Publisher's description.