Sodium Calcium Exchange A Growing Spectrum Of Pathophysiological Implications

Author : Lucio Annunziato
Publisher : Springer Science & Business Media
Page : 457 pages
File Size : 52,7 Mb
Release : 2012-12-09
Category : Medical
ISBN : 9781461447566

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Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications by Lucio Annunziato Pdf

This book reports the text of the lectures of the 6th International Conference on Sodium Calcium Exchange held in Lacco Ameno in the Island of Ischia in the Gulf of Naples, Italy, from October 1 to October 5, 2011. The present book uncovers the most striking new findings on NCX that emerged since the previous Conference on Sodium Calcium Exchange, such as the structural dissection of the molecular determinants of Ca2+ sensitivity of the exchanger, the epigenetic regulation of ncx1 gene, the molecular identification of the mitochondrial Sodium Calcium Exchanger, and the discovery of NCX in unexpected anatomical locations such as the female reproductive tract. The book is organized into 11 parts covering NCX structural aspects, genetic and epigenetic regulation, regulatory mechanisms, subcellular localization in mitochondria, involvement in neurodegenerative diseases and in immune regulation, and the role of the cardiovascular and endocrine systems, as well as diabetes in physiology and pathophysiology. Selected chapters of the book are also devoted to the interaction of NCKX and other ion channels and transporters with NCX, like ASICs, TRPM, and NHE.

Author : Dieter Wicher,Frédéric Marion-Poll
Publisher : Frontiers Media SA
Page : 176 pages
File Size : 48,8 Mb
Release : 2019-02-08
Category : Electronic
ISBN : 9782889457489

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Function and Regulation of Chemoreceptors by Dieter Wicher,Frédéric Marion-Poll Pdf

To perceive environmental chemical compounds and to convert these external signals into an intracellular message might be the oldest way for a living being to get information from the outside world. Chemoreceptors are proteins or protein complexes that detect molecules from the outside world either at distance (olfaction) or at close range (gustation). Chemoreceptors can operate as ionotropic or as metabotropic receptors. Ionotropic receptors form ion channels that are activated via ligand binding. Activation of a metabotropic receptor initiates an intracellular signaling cascade that could include a change of enzymatic activity, production of second messenger or activation of ion channels. The receptor performance has to be fine-tuned according to the actual physiological requirements and the presentation of the chemical signal. This Research Topic collects reports and reviews on structure and function of chemoreceptors in the animal kingdom, and how these receptors are regulated.

Author : Anonim
Publisher : Unknown
Page : 1488 pages
File Size : 46,7 Mb
Release : 1993
Category : Medicine
ISBN : MINN:31951D00878048X

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Cumulated Index Medicus by Anonim Pdf

Author : Institute of Medicine,Committee on Fluid Resuscitation for Combat Casualties
Publisher : National Academies Press
Page : 208 pages
File Size : 54,5 Mb
Release : 1999-11-05
Category : Medical
ISBN : 9780309064811

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Fluid Resuscitation by Institute of Medicine,Committee on Fluid Resuscitation for Combat Casualties Pdf

Historically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood lossâ€"hemorrhageâ€"is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties. In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research. The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.

Author : Shaul Massry
Publisher : Springer Science & Business Media
Page : 611 pages
File Size : 53,8 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781461342175

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Phosphate Metabolism by Shaul Massry Pdf

We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year.

Author : Robert Fitridge,M. M. Thompson
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 49,9 Mb
Release : 2011
Category : Medical
ISBN : 9781922064004

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Mechanisms of Vascular Disease by Robert Fitridge,M. M. Thompson Pdf

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Author : Ambrose S. Kibos,Bradley P. Knight,Vidal Essebag,Steven B. Fishberger,Mark Slevin,Ion C. Țintoiu
Publisher : Springer Science & Business Media
Page : 678 pages
File Size : 43,7 Mb
Release : 2013-12-13
Category : Medical
ISBN : 9781447153160

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Cardiac Arrhythmias by Ambrose S. Kibos,Bradley P. Knight,Vidal Essebag,Steven B. Fishberger,Mark Slevin,Ion C. Țintoiu Pdf

This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.​

Author : Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publisher : National Academies Press
Page : 444 pages
File Size : 43,7 Mb
Release : 2011-07-01
Category : Medical
ISBN : 9780309210089

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Nutrition and Traumatic Brain Injury by Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain Pdf

Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Author : Klaus Olgaard,Isidro B. Salusky,Justin Silver
Publisher : Oxford University Press
Page : 617 pages
File Size : 43,8 Mb
Release : 2010-06-10
Category : Medical
ISBN : 9780199559176

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The Spectrum of Mineral and Bone Disorders in Chronic Kidney Disease by Klaus Olgaard,Isidro B. Salusky,Justin Silver Pdf

Rev. ed. of: Spectrum of renal osteodystrophy / edited by Tilman Drueke, Isidro B. Salusky. 1st. 2001.

Author : Anonim
Publisher : Unknown
Page : 2388 pages
File Size : 54,7 Mb
Release : 2004
Category : Medicine
ISBN : MINN:31951P00992561K

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 45,5 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author : Anonim
Publisher : Unknown
Page : 460 pages
File Size : 43,6 Mb
Release : 1991-03
Category : Agriculture
ISBN : PSU:000057553689

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Bibliography of Agriculture by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 1408 pages
File Size : 53,9 Mb
Release : 1971
Category : Diabetes
ISBN : UTEXAS:059171102461870

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Diabetes Literature Index by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 586 pages
File Size : 43,6 Mb
Release : 1995
Category : Agriculture
ISBN : UOM:39015036998691

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Bibliography of Agriculture with Subject Index by Anonim Pdf

Author : Susumu Seino,Graeme I. Bell
Publisher : Springer Science & Business Media
Page : 475 pages
File Size : 50,6 Mb
Release : 2008-04-08
Category : Science
ISBN : 9784431754527

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Pancreatic Beta Cell in Health and Disease by Susumu Seino,Graeme I. Bell Pdf

The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.