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Author : Atta-ur-Rahman,Zahir Shah
Publisher : Springer Science & Business Media
Page : 534 pages
File Size : 47,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461383277
Author : Erick M. Carreira,Lisbet Kvaerno
Publisher : John Wiley & Sons
Page : 664 pages
File Size : 52,7 Mb
Release : 2009-02-09
Category : Science
ISBN : 3527324526
Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.
Author : Zahir Shah
Publisher : Unknown
Page : 540 pages
File Size : 51,6 Mb
Release : 1993-05-21
Category : Organic compounds
ISBN : 1461383285
Author : Mihály Nógrádi
Publisher : John Wiley & Sons
Page : 386 pages
File Size : 51,6 Mb
Release : 2008-07-11
Category : Science
ISBN : 9783527615681
The state-of-the-art in stereoselective synthesis! Thoroughly revised and updated, this enlarged second edition offers a plethora of valuable information on methods and reagents in stereoselective synthesis. Methods have been selected for high efficiency and selectivity; mechanistic aspects are treated succinctly, with a strong emphasis on practical applications. For this new edition, material has been added on * homogeneous diastereoselective hydrogenations * enantioselective oxidations * novel, efficient chiral auxiliaries Much of the information given is presented in figures and tables, which makes the book a valuable reference work for the practically minded organic chemist. From reviews of the first edition: 'The extensive material in the volume should prove particularly useful to anyone involved in synthetic chemistry or teaching a course in organic chemistry.' Journal of Medicinal Chemistry 'With nearly 1400 references cited, the book contains a wealth of information and should be a useful addition to the chemist's library.' The American Scientist
Author : Mihály Nógrádi,László Poppe,József Nagy,Gábor Hornyánszky,Zoltán Boros
Publisher : John Wiley & Sons
Page : 280 pages
File Size : 49,8 Mb
Release : 2016-06-22
Category : Science
ISBN : 9783527696314
Written by a well-respected and experienced author, this textbook fills the gap for a concise introduction to the key concepts of organic stereochemistry and the most important classical and modern methods in stereoselective synthesis. The concepts are extensively illustrated in color, with practical examples and question-answer sets to help consolidate the reader's knowledge. In addition, animations are available from the Wiley website. A must-have for students in chemistry, biochemistry, and life sciences, as well as researchers in pharmaceutical and agrochemical companies in need of a quick introduction to the field.
Author : Vasyl Andrushko,Natalia Andrushko
Publisher : John Wiley & Sons
Page : 1836 pages
File Size : 54,6 Mb
Release : 2013-08-16
Category : Science
ISBN : 9781118628331
Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.
Author : Jean Rodriguez,Damien Bonne
Publisher : John Wiley & Sons
Page : 480 pages
File Size : 46,8 Mb
Release : 2015-04-08
Category : Science
ISBN : 9781119006428
Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. • Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development • Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists • Organizes chapters by molecular structure of final products, making for a handbook-style resource • Discusses applications of the synthesis of natural products and of drug intermediates • Brings together otherwise-scattered information about a number of key, efficient chemical reactions
Author : Garry Procter
Publisher : Unknown
Page : 91 pages
File Size : 55,5 Mb
Release : 2007
Category : Organic compounds
ISBN : 0191849383
Stereoselective organic synthesis can be used for the selective preparation of new organic compounds with a defined and predictable three-dimensional architecture. This book offers an introduction to the chemistry involved.
Author : Maurizio Benaglia
Publisher : Walter de Gruyter GmbH & Co KG
Page : 606 pages
File Size : 43,6 Mb
Release : 2021-07-19
Category : Science
ISBN : 9783110588729
Organocatalysis is considered today one of the three pillars in asymmetric catalysis, along with biocatalysis and organometallic catalysis. The current book gives an overview of the new reactions, the catalysts and their activation strategies reported in recent years. In addition, the applications of organocatalysis in total synthesis, radical reactions, flow chemistry and industrial practice are discussed.
Author : Robert S. Atkinson
Publisher : Unknown
Page : 552 pages
File Size : 52,6 Mb
Release : 1995-09-13
Category : Science
ISBN : UOM:39015034446867
Introduces a new classification for stereoselective reactions based on the number of chiral centres contained in the starting material and the product. Based on stereochemical terms, this classification enables users to apply methods for the synthesis of target molecules.
Author : Tse-Lok Ho
Publisher : Wiley-Interscience
Page : 360 pages
File Size : 53,7 Mb
Release : 1999-03-25
Category : Science
ISBN : UOM:39015045994897
Many chemicals are found in "right-" and "left-handed" forms that may react differently in the body. In planning a synthesis, chemists must know how to select the best method for making the preferred form of a chemical. This book shows how to choose the best method for a given synthesis. It provides readers with a thorough understanding of stereoselectivity in organic and medicinal chemistry as well as the pharmaceutical, agricultural, and food industries.
Author : Robert S. Ward
Publisher : John Wiley & Sons
Page : 194 pages
File Size : 53,6 Mb
Release : 1999-05-04
Category : Science
ISBN : UOM:39015050252199
Selectivity is an important part of organic synthesis. The whole basis of organic chemistry, and especially organic synthesis, depends upon the selectivity which can be achieved in organic reactions. This concise textbook describes the strategies which can be adopted to improve selectivity, and the reactions which have been specially designed to afford high selectivity. The book illustrates the range of processes to which these principles can be applied and the high degree of selectivity which can be achieved. Selectivity in Organic Synthesis provides a solid introduction to this subject, focusing on the key areas and applications. Selectivity in Organic Synthesis features: * A concise introduction to selectivity in organic chemistry. * Lucidly written text including many carefully chosen examples and applications. * Numerous problems along with their solutions to help and encourage the reader. Suitable for organic chemistry students taking a course on organic synthesis or asymmetric synthesis in the 3rd or final year of an undergraduate chemistry course or in the first year of a postgraduate course.
Author : Eckhard Ottow,Klaus Schöllkopf,Bernd-Günter Schulz
Publisher : Springer Science & Business Media
Page : 147 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642784965
Devising methods and reagents for stereoselective synthesis is an intellectually demanding venture. Six experts on diastereo- and enantioselective synthesis contributed their papers to this volume. They were presented at a symposium on stereoselective synthesis to honour Professor Dr. Dr. h.c. Rudolf Wiechert's achievements in medicinal chemistry research. The symposium was organized by the Schering AG on the occasion of Professor Wiechert's 65th birthday.
Author : Atta-ur- Rahman
Publisher : Elsevier
Page : 731 pages
File Size : 48,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483100975
Studies in Natural Products Chemistry, Volume 10: Stereoselective Synthesis (Part F) is a collection of articles about studies on important organic molecules. The book covers studies such as that on the synthesis of cembranes as well as its natural occurrence and bioactivity; the stereoselective synthesis of Vitamin D; the synthesis of isoquinolinequinone antibiotics; and the nucleophilic addition chemistry of polyunsaturated carbonyl compounds. Also covered in the book are subjects such as developments in the synthesis of medium ring ethers; the biological properties, chemistry, and synthesis of didemnins; and natural products synthesis based on novel ring transformation. The text is recommended for organic chemists who would like to know more about the progresses in the study of important organic molecules and their implications in different fields.
Author : Jianbo Wang
Publisher : Springer
Page : 283 pages
File Size : 52,7 Mb
Release : 2012-08-13
Category : Science
ISBN : 9783642318245
Stereoselective Synthesis of Tetrasubstituted Alkenes via Torquoselectivity-Controlled Olefination of Carbonyl Compounds with Ynolates, by Mitsuru Shindo and Kenji Matsumoto.- Stereoselective Synthesis of Z-Alkenes, by Woon-Yew Siau, Yao Zhang and Yu Zhao.- Stereoselective Synthesis of Mono-fluoroalkenes, by Shoji Hara.- Recent Advances in Stereoselective Synthesis of 1,3-Dienes, by Michael De Paolis, Isabelle Chataigner and Jacques Maddaluno.- Selective Olefination of Carbonyl Compounds via Metal-Catalyzed Carbene Transfer from Diazo Reagents, by Yang Hu and X. Peter Zhang.- Selective Alkene Metathesis in the Total Synthesis of Complex Natural Product, by Xiaoguang Lei and Houhua Li.- Olefination Reactions of Phosphorus-Stabilized Carbon Nucleophiles, by Yonghong Gu and Shi-Kai Tian.- Alkene Synthesis Through Transition Metal-Catalyzed Cross-Coupling of N-Tosylhydrazones, by Yan Zhang and Jianbo Wang.
