Studies On Myocardial Energy Metabolism

Author : Gary D. Lopaschuk,Naranjan S. Dhalla
Publisher : Springer
Page : 301 pages
File Size : 48,7 Mb
Release : 2014-08-22
Category : Science
ISBN : 9781493912278

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Cardiac Energy Metabolism in Health and Disease by Gary D. Lopaschuk,Naranjan S. Dhalla Pdf

The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Author : J.W. de Jong
Publisher : Springer Science & Business Media
Page : 571 pages
File Size : 53,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400913196

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Myocardial Energy Metabolism by J.W. de Jong Pdf

Author : Kalervo Hiltunen
Publisher : Unknown
Page : 43 pages
File Size : 42,7 Mb
Release : 1977
Category : Myocardium
ISBN : 9514204921

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Studies on Myocardial Energy Metabolism by Kalervo Hiltunen Pdf

Author : Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran
Publisher : Frontiers Media SA
Page : 89 pages
File Size : 54,6 Mb
Release : 2019-08-08
Category : Electronic
ISBN : 9782889459384

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Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease by Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Richard J. Kones
Publisher : Blackwell Publishers
Page : 472 pages
File Size : 53,5 Mb
Release : 1975
Category : Medical
ISBN : UOM:39015000892383

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Glucose, Insulin, Potassium, and the Heart by Richard J. Kones Pdf

Author : V. N. Smirnov,Arnold M. Katz
Publisher : CRC Press
Page : 700 pages
File Size : 54,7 Mb
Release : 1987
Category : Calcium
ISBN : 371860311X

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Myocardial Metabolism by V. N. Smirnov,Arnold M. Katz Pdf

Author : Vasken Dilsizian,Gerald M. Pohost
Publisher : John Wiley & Sons
Page : 525 pages
File Size : 42,9 Mb
Release : 2011-09-14
Category : Medical
ISBN : 9781444347968

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Cardiac CT, PET and MR by Vasken Dilsizian,Gerald M. Pohost Pdf

This careful revision keeps pace with developments in the field, with new chapters on PET Metabolism, CT and MRI in the Emergency Department, Image-Guided Electrophysiology Mapping and Ablation, and Identification of Vulnerable Atherosclerotic Plaque by Radionuclide and CT techniques, plus the introduction of new contributors Udo Hoffman and Stephan Achenbach. Praised in its previous edition as a concise source of essential information, this new edition presents the most recent information in an accessible format and serves as an excellent reference source for all cardiologists, radiologists and nuclear medicine physicians.

Author : International Study Group for Research in Cardiac Metabolism
Publisher : Unknown
Page : 878 pages
File Size : 51,6 Mb
Release : 1974
Category : Electronic
ISBN : 3541063416

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Myocardial Metabolism by International Study Group for Research in Cardiac Metabolism Pdf

Author : Michael Schwarzer,Torsten Doenst
Publisher : Academic Press
Page : 240 pages
File Size : 47,5 Mb
Release : 2015-11-04
Category : Medical
ISBN : 9780128026144

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The Scientist's Guide to Cardiac Metabolism by Michael Schwarzer,Torsten Doenst Pdf

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field

Author : H. Böhles,A. C. Sewell
Publisher : CRC Press
Page : 188 pages
File Size : 52,8 Mb
Release : 2004
Category : Cardiomyopathy
ISBN : 3887631048

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Metabolic Cardiomyopathy by H. Böhles,A. C. Sewell Pdf

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Author : N. S. Dhalla
Publisher : Unknown
Page : 128 pages
File Size : 51,8 Mb
Release : 1974
Category : Electronic
ISBN : OCLC:464068210

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Myocardial Biology by N. S. Dhalla Pdf

Author : Gary D. Lopaschuk,Mario Marzilli
Publisher : Unknown
Page : 100 pages
File Size : 55,6 Mb
Release : 2013
Category : Electronic
ISBN : 2902050135

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Cardiac Energy Metabolism by Gary D. Lopaschuk,Mario Marzilli Pdf

Author : Joanne S. Ingwall
Publisher : Springer Science & Business Media
Page : 272 pages
File Size : 47,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461510932

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ATP and the Heart by Joanne S. Ingwall Pdf

ATP plays a central role in the two leading causes of cardiac morbidity and mortality in the western world: ischemia and heart failure. We are in our infancy applying what is known about biology and chemistry of ATP toward developing effective therapies for these diseases. In this volume, the current understanding of the chemistry and biology of ATP specifically in the cardiomyocyte is presented. New insights into ATP have been gleaned using biophysical techniques allowing dynamic measurement of chemical events in the intact beating heart and using new animal models in which cardiac proteins are either over expressed, deleted or harbor specific mutations. This book provides a summary of the basic understanding and includes illustrations of why ATP and the Heart is important to both the clinician and scientist.

Author : Stephen T. Sinatra
Publisher : Basic Health Publications, Inc.
Page : 276 pages
File Size : 47,9 Mb
Release : 2007-10
Category : Carnitine
ISBN : 1591202167

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The Sinatra Solution by Stephen T. Sinatra Pdf

A board-certified cardiologist discusses the importance of energy metabolism on cardiovascular health and the positive impact three energy-supplying nutrients--CoQ10, Carnitine, and Ribose--have on the cardiovascular system.

Author : Leslie A. Pray,Institute of Medicine,Ann L. Yaktine,Food and Nutrition Board,Board on Health Sciences Policy,Diana E. Pankevich,Planning Committee for a Workshop on Potential Health Hazards Associated with Consumption of Caffeine in Food and Dietary Supplements
Publisher : Unknown
Page : 0 pages
File Size : 46,6 Mb
Release : 2014
Category : Health & Fitness
ISBN : 0309297494

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Caffeine in Food and Dietary Supplements by Leslie A. Pray,Institute of Medicine,Ann L. Yaktine,Food and Nutrition Board,Board on Health Sciences Policy,Diana E. Pankevich,Planning Committee for a Workshop on Potential Health Hazards Associated with Consumption of Caffeine in Food and Dietary Supplements Pdf

Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.