Surviving Hypoxia

Author : Peter W. Hochachka,Peter L. Lutz,Thomas J. Sick,Myron Rosenthal
Publisher : CRC Press
Page : 592 pages
File Size : 42,5 Mb
Release : 1993-03-24
Category : Medical
ISBN : 0849342260

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Surviving Hypoxia by Peter W. Hochachka,Peter L. Lutz,Thomas J. Sick,Myron Rosenthal Pdf

Surviving Hypoxia: Mechanisms of Control and Adaptation is a synthesis of findings and thoughts concerning hypoxia. The thermodynamics of hypoxia are discussed in detail, including acid-base balance and self-pollution resulting from the accumulation of anaerobic end-products. The book focuses on descriptions and discussions of common facets, contrasting solutions in a variety of physiological hypoxia defense strategies, including those shown by plants, invertebrates, and vertebrates. Special treatment is given to the distinctive problems that hypoxia presents to vulnerable organs such as the kidney, liver, and brain. It also addresses pathological events in addition to protective mechanisms. Clinical implications of basic research are examined in the book, which provides new insights into underlying pathological processes occuring in hypoxic-induced organ failure and indicates new paths for successful clinical intervention. Surviving Hypoxia: Mechanisms of Control and Adaptation is an excellent reference for all researchers interested in the physiological effects of hypoxia, underlying pathological events, and protective mechanisms.

Author : Peter W. Hochachka,Peter L. Lutz,Thomas J. Sick,Myron Rosenthal
Publisher : CRC Press
Page : 587 pages
File Size : 49,7 Mb
Release : 2022-11-30
Category : Medical
ISBN : 9781000714210

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Surviving Hypoxia by Peter W. Hochachka,Peter L. Lutz,Thomas J. Sick,Myron Rosenthal Pdf

Surviving Hypoxia: Mechanisms of Control and Adaptation is a synthesis of findings and thoughts concerning hypoxia. The thermodynamics of hypoxia are discussed in detail, including acid-base balance and self-pollution resulting from the accumulation of anaerobic end-products. The book focuses on descriptions and discussions of common facets, contrasting solutions in a variety of physiological hypoxia defense strategies, including those shown by plants, invertebrates, and vertebrates. Special treatment is given to the distinctive problems that hypoxia presents to vulnerable organs such as the kidney, liver, and brain. It also addresses pathological events in addition to protective mechanisms. Clinical implications of basic research are examined in the book, which provides new insights into underlying pathological processes occuring in hypoxic-induced organ failure and indicates new paths for successful clinical intervention. Surviving Hypoxia: Mechanisms of Control and Adaptation is an excellent reference for all researchers interested in the physiological effects of hypoxia, underlying pathological events, and protective mechanisms.

Author : Elena Loreti,Gustavo Striker
Publisher : MDPI
Page : 288 pages
File Size : 52,9 Mb
Release : 2021-03-02
Category : Science
ISBN : 9783036501482

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Plant Responses to Hypoxia by Elena Loreti,Gustavo Striker Pdf

Molecular oxygen deficiency leads to altered cellular metabolism and can dramatically reduce crop productivity. Nearly all crops are negatively affected by a lack of oxygen (hypoxia) due to adverse environmental conditions such as excessive rain and soil waterlogging. Extensive efforts to fully understand how plants sense oxygen deficiency and their ability to respond using different strategies are crucial to increase hypoxia tolerance. Progress in our understanding has been significant in recent years. This topic certainly deserves more attention from the academic community; therefore, we have compiled a series of articles reflecting the advancements made thus far.

Author : Peter L. Lutz,Goran E. Nilsson
Publisher : R G Landes Company
Page : 207 pages
File Size : 47,6 Mb
Release : 1997-01-01
Category : Science
ISBN : 1570594589

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The Brain Without Oxygen by Peter L. Lutz,Goran E. Nilsson Pdf

Author : Eetu Hämäläinen
Publisher : Nova Publishers
Page : 332 pages
File Size : 40,5 Mb
Release : 2008
Category : Medical
ISBN : 1604561408

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New Trends in Brain Hypoxia Ischemia Research by Eetu Hämäläinen Pdf

This book presents recent and significant research from around the world dedicated to brain hypoxia-ischemia which is a disorder characterised by a reduction in oxygen supply (hypoxia) combined with reduced blood flow (ischemia) to the brain. This condition may result from a localised obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain edema; coma; and other conditions.

Author : Shyamala Dakshinamurti
Publisher : CRC Press
Page : 268 pages
File Size : 47,9 Mb
Release : 2021-10-29
Category : Medical
ISBN : 9781000442328

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Hypoxic Respiratory Failure in the Newborn by Shyamala Dakshinamurti Pdf

We have all been hypoxic. Fetal tolerance for intrauterine hypoxia arises from evolutionarily conserved physiological mechanisms, the antecedents of which can be learned from diving mammals or species at high altitudes. Understanding fetal hypoxia leads to understanding the huge physiological shifts of neonatal transition and the dangers of perinatal hypoxia. This comprehensive volume of topical review articles by expert authors addresses the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit, as well as the classification, diagnosis, and clinical management of hypoxic respiratory failure and persistent pulmonary hypertension in the term neonate. The goal of Hypoxic Respiratory Failure in the Newborn is to connect our understanding of hypoxia from animals in extreme environments, with how the human fetus handles its hypoxic environment; and why the human newborn suddenly cannot. The book will educate health care professionals on how to care for newborns with hypoxic respiratory failure, including the use of up-to-date diagnostic tools and therapies. It also highlights areas of controversy and ongoing research in hypoxic respiratory failure and pulmonary hypertension of the newborn, including challenging case studies. Key Features Explores evolutionary context and comparative physiology of hypoxia tolerance in the fetus and neonate, from basic research to clinical scenarios Provides guidance to trainees, physicians, and allied health professionals engaged in NICU care; pediatricians, cardiologists, pulmonologists, anesthesiologists, neonatologists, and physiologists to effectively manage infants in hypoxic respiratory failure Includes case scenarios emphasizing current diagnostic and therapeutic controversies and algorithmic approaches to decipher difficult clinical cases

Author : P.L. Lutz,G.E. Nilsson,H.M. Prentice
Publisher : Springer Science & Business Media
Page : 252 pages
File Size : 52,9 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9780306481970

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The Brain Without Oxygen by P.L. Lutz,G.E. Nilsson,H.M. Prentice Pdf

It is well known and researched, that deprivation of oxygen to the brain can quickly result in irreversible damage and death. What is less well known, is that some vertebrate species are exceptionally tolerant of brain hypoxia. The Brain Without Oxygen: Causes of failure - Physiological and molecular mechanisms for survival, Third edition, discusses the mechanisms of brain hypoxia tolerance in these exceptional vertebrates, which include diving marine mammals, high altitude dwellers and the hibernating mammal. Special attention is given to the extraordinary adaptations that allow a few turtle and fish species to tolerate months of brain anoxia. This third, fully updated edition addresses the potential of these animal models as targets for human clinical intervention. Perhaps the most interesting of these, are those involved in the suppression of metabolic activities to new set points well below their normoxic minima or maintenance levels. This volume will be valuable reading for researchers in physiology, medicine and general biological sciences, and of great importance to pharmaceutical companies researching novel models for stroke and brain ischemia.

Author : Jeffrey G. Richards,Anthony P. Farrell,Colin J. Brauner
Publisher : Academic Press
Page : 517 pages
File Size : 53,6 Mb
Release : 2009-03-10
Category : Technology & Engineering
ISBN : 0080877990

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Fish Physiology: Hypoxia by Jeffrey G. Richards,Anthony P. Farrell,Colin J. Brauner Pdf

Periods of environmental hypoxia (Low Oxygen Availability) are extremely common in aquatic systems due to both natural causes such as diurnal oscillations in algal respiration, seasonal flooding, stratification, under ice cover in lakes, and isolation of densely vegetated water bodies, as well as more recent anthropogenic causes (e.g. eutrophication). In view of this, it is perhaps not surprising that among all vertebrates, fish boast the largest number of hypoxia tolerant species; hypoxia has clearly played an important role in shaping the evolution of many unique adaptive strategies. These unique adaptive strategies either allow fish to maintain function at low oxygen levels, thus extending hypoxia tolerance limits, or permit them to defend against the metabolic consequences of oxygen levels that fall below a threshold where metabolic functions cannot be maintained. The aim of this volume is two-fold. First, this book will review and synthesize the adaptive behavioural, morphological, physiological, biochemical, and molecular strategies used by fish to survive hypoxia exposure and place them within an environmental and ecological context. Second, through the development of a synthesis chapter this book will serve as the cornerstone for directing future research into the effects of hypoxia exposures on fish physiology and biochemistry. The only single volume available to provide an in-depth discussion of the adaptations and responses of fish to environmental hypoxia Reviews and synthesizes the adaptive behavioural, morphological, physiological, biochemical, and molecular strategies used by fish to survive hypoxia exposure Includes discussion of the evolutionary and ecological consequences of hypoxia exposure in fish

Author : Anonim
Publisher : Academic Press
Page : 592 pages
File Size : 51,9 Mb
Release : 2007-11-08
Category : Science
ISBN : 0080554865

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Oxygen Biology and Hypoxia by Anonim Pdf

For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume features articles on the topic of oxygen biology and hypoxia.

Author : Robert C. Roach,Peter D. Wagner,Peter H. Hackett
Publisher : Springer Science & Business Media
Page : 466 pages
File Size : 43,8 Mb
Release : 2002-01-31
Category : Medical
ISBN : 0306466961

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Hypoxia by Robert C. Roach,Peter D. Wagner,Peter H. Hackett Pdf

Hypoxia remains a constant threat throughout life. It is for this reason that the International Hypoxia Society strives to maintain a near quarter century tradition of presenting a stimulating blend of clinical and basic science discussions. International experts from many fields have focused on the state-of-the-art discoveries in normal and pathophysiological responses to hypoxia. Topics in this volume include gene-environment interactions, a theme developed in both a clinical context regarding exercise and hypoxia, as well as in native populations living in high altitudes. Furthermore, experts in the field have combined topics such as skeletal muscle angiogenesis and hypoxia, high altitude pulmonary edema, new insights into the biology of the erythropoietin receptor, and the latest advances in cardiorespiratory control in hypoxia. This volume explores the fields of anatomy, cardiology, biological transport, and biomedical engineering among many others.

Author : Anonim
Publisher : ScholarlyEditions
Page : 1453 pages
File Size : 51,9 Mb
Release : 2012-01-09
Category : Technology & Engineering
ISBN : 9781464964541

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Issues in Biomedical Engineering Research and Application: 2011 Edition by Anonim Pdf

Issues in Biomedical Engineering Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biomedical Engineering Research and Application. The editors have built Issues in Biomedical Engineering Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biomedical Engineering Research and Application in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biomedical Engineering Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Gabriel G. Haddad,Shan Ping Yu
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 52,7 Mb
Release : 2009-01-06
Category : Medical
ISBN : 9781603275798

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Brain Hypoxia and Ischemia by Gabriel G. Haddad,Shan Ping Yu Pdf

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development. This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

Author : Peter L. Lutz,Goran E. Nilsson
Publisher : Unknown
Page : 207 pages
File Size : 44,7 Mb
Release : 1997-01-01
Category : Adaptation (Physiology)
ISBN : 3540631313

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The Brain Without Oxygen by Peter L. Lutz,Goran E. Nilsson Pdf

This book discusses the problem of how any interruption in energy supply to the brain of more than a few minutes results in irreversible damage. From a comparative perspective, the book presents the most recent findings concerning the pathological processes occurring in brain hypoxia and discusses in detail the defense mechanisms that allow the brains of a few vertebrate species to survive anoxia for long periods of time. It describes the processes underlying the enhanced hypoxid tolerance shown by the brains of the mammalian neonate, the hibernating mammal and the diving marine mammal. The book identifies the key processes that are protected in anoxia tolerant animals, which allow new insights into the survival hierarchy of the many systems that collapse in the energy-deprived mammalian brain.

Author : Hemanshu Prabhakar
Publisher : Academic Press
Page : 500 pages
File Size : 54,6 Mb
Release : 2016-02-11
Category : Medical
ISBN : 9780128041130

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Complications in Neuroanesthesia by Hemanshu Prabhakar Pdf

Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients. Quick and easy reference for understanding problems in neuroanesthesia Provides comprehensive insights into all possible complications occurring during perioperative management of neurosurgical and neurologic patients Includes useful section with clinical case studies of complications in neuroanesthesia

Author : Jing Zheng,Chi Zhou
Publisher : BoD – Books on Demand
Page : 456 pages
File Size : 53,7 Mb
Release : 2017-02-01
Category : Medical
ISBN : 9789535128953

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Hypoxia and Human Diseases by Jing Zheng,Chi Zhou Pdf

This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.