Brain Hypoxia And Ischemia

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Brain Hypoxia and Ischemia

Author : Gabriel G. Haddad,Shan Ping Yu
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 49,8 Mb
Release : 2009-01-06
Category : Medical
ISBN : 9781603275798

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Brain Hypoxia and Ischemia by Gabriel G. Haddad,Shan Ping Yu Pdf

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development. This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

New Trends in Brain Hypoxia Ischemia Research

Author : Eetu Hämäläinen
Publisher : Nova Publishers
Page : 332 pages
File Size : 50,6 Mb
Release : 2008
Category : Medical
ISBN : 1604561408

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New Trends in Brain Hypoxia Ischemia Research by Eetu Hämäläinen Pdf

This book presents recent and significant research from around the world dedicated to brain hypoxia-ischemia which is a disorder characterised by a reduction in oxygen supply (hypoxia) combined with reduced blood flow (ischemia) to the brain. This condition may result from a localised obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain edema; coma; and other conditions.

Brain Hypoxia and Ischemia: New Insights Into Neurodegeneration and Neuroprotection

Author : Natalia N Nalivaeva,Elena A Rybnikova
Publisher : Frontiers Media SA
Page : 162 pages
File Size : 49,7 Mb
Release : 2019-11-15
Category : Electronic
ISBN : 9782889631179

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Brain Hypoxia and Ischemia: New Insights Into Neurodegeneration and Neuroprotection by Natalia N Nalivaeva,Elena A Rybnikova Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Brain Hypoxia-Ischemia Research Progress

Author : Océane M. Roux
Publisher : Nova Publishers
Page : 314 pages
File Size : 45,6 Mb
Release : 2008
Category : Cerebral anoxia
ISBN : 1604561394

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Brain Hypoxia-Ischemia Research Progress by Océane M. Roux Pdf

Brain hypoxia-ischemia is a disorder characterised by a reduction in oxygen supply (hypoxia) combined with reduced blood flow (ischemia) to the brain. This condition may result from a localised obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain oedema; coma; and other conditions. This book presents the latest research in this field from around the world.

Mechanisms of Cerebral Hypoxia and Stroke

Author : G. Somjen
Publisher : Springer Science & Business Media
Page : 474 pages
File Size : 40,7 Mb
Release : 2013-03-13
Category : Science
ISBN : 9781468455625

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Mechanisms of Cerebral Hypoxia and Stroke by G. Somjen Pdf

The articles and short communications in this volume are based on papers pre sented to the Symposium on Cerebral Hypoxia and Stroke held in Budapest in August of 1987. Besides participants at the meeting, three scientists who were invited but could not attend have also contributed chapters to this volume. A synopsis of the general discussion at the conference and a review chapter conclude this volume. To the readers of this book it will not be news that stroke is a worldwide problem. Efforts to cope with this often devastating condition are worldwide also, as attested by the international membership of the conference. It has been said of oxygen deficiency that it not only stops the machine, it also wrecks the machinery. The paramount question in stroke research is this: why can't the brain be restarted after a hypoxic episode in much the same manner as a motor car can when its gas tank is refilled after it stalled because it ran out of fuel? Participants at the Symposium had been requested in advance of the meeting to especially consider a series of specific questions in relation to this general problem. Among these specific questions were: the mechanism of synaptic blockade in hypoxic brain tissue; the transition from reversible to irreversible arrest of function; the nature of postischemic (delayed) cell death; the possible basic differences in the consequences of hypoxia and ischemia; and actual and potential approaches to the prevention and treatment of cell damage in hypoxia and stroke.

Hypoxia

Author : Robert C. Roach,Peter D. Wagner,Peter H. Hackett
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 51,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461547112

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Hypoxia by Robert C. Roach,Peter D. Wagner,Peter H. Hackett Pdf

Hypoxia is a constant threat throughout life. International experts from many different fields, including clinicians, clinical researchers, and basic scientists, have contributed to this volume, presenting state-of-the-art information regarding normal and abnormal (pathophysiological) responses to hypoxia. The topics covered include visitors to high altitude, the latest developments on high-altitude cerebral and pulmonary edema, the brain in hypoxia, high-altitude headache, and similarities between ischemic and hypoxic injury to the brain. In addition topics are covered such as blood-brain barrier in hypoxia, hypoxia interactions with vascular growth, and how humans adjust to extreme hypoxia.

Neurohospitalist Medicine

Author : S. Andrew Josephson,W. David Freeman,David J. Likosky
Publisher : Cambridge University Press
Page : 128 pages
File Size : 45,7 Mb
Release : 2011-09-29
Category : Medical
ISBN : 9781139501828

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Neurohospitalist Medicine by S. Andrew Josephson,W. David Freeman,David J. Likosky Pdf

Over the past decade, the hospitalist model has become a dominant system for the delivery of inpatient care. Forces such as national mandates to improve safety and quality, and intense pressure to safely reduce length of hospital stays, are now exerting pressure on neurologists. To meet these challenges, a new neurohospitalist model is emerging. This is the first authoritative text to detail the advances and strategies for treating neurologic disease in a hospital setting. It includes chapters on specific acute neurologic diseases including stroke, epilepsy, neuromuscular disease and traumatic brain injury and also addresses common reasons for neurologic consultation in the hospital including encephalopathy, electrolyte disturbances and neurologic complications of pregnancy. Ethical and structural issues commonly encountered in neurologic inpatients are also addressed. This will be a key resource for any clinician or trainee caring for neurologic patients in the hospital including practising neurologists, internists and trainees across multiple subspecialities.

Seizures in Critical Care

Author : Panayiotis Varelas
Publisher : Springer Science & Business Media
Page : 391 pages
File Size : 42,9 Mb
Release : 2008-08-17
Category : Medical
ISBN : 9781592598410

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Seizures in Critical Care by Panayiotis Varelas Pdf

A panel of international ICU and epilepsy physicians and researchers detail the epileptic phenomena that occur in the complex environment of the ICU. Focusing on the central nervous system, the authors systematically examine the most up-to-date evidenced-based data regarding ICU seizures, including their most frequent causes, their pathophysiology, their clinical presentation, and the diagnostic evaluation needed to confirm their presence. They also discuss the challenges and specifics of the management of ICU seizures, reviewing the new antiepileptics and their interaction with other ICU medications, drugs with epileptogenic properties used in the ICU, and the role of the new enterally available antiepileptics in treating seizures. Numerous tables summarize drug interactions, neuroimages reveal common ICU seizure etiologies, and multiple electroencephalographic recordings demonstrate clinical or subclinical seizures in ICU patients.

Cerebral Ischemia and Resuscitation

Author : Avital Schurr,Benjamin M. Rigor
Publisher : CRC Press
Page : 456 pages
File Size : 50,7 Mb
Release : 1990-09-24
Category : Science
ISBN : 0849367158

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Cerebral Ischemia and Resuscitation by Avital Schurr,Benjamin M. Rigor Pdf

This fascinating monograph is filled with information formerly found only in periodicals and symposia proceedings. Chapters discuss the different models of cerebral ischemia in use today, including their advantages and disadvantages. This one-of-a-kind resource also contains essential chapters on cellular mechanisms of ion and acid-base homeostases, and energy metabolism of the ischemic brain. It reviews the possible role of lipids, free fatty acids, and free radicals. Four chapters are devoted to neurotransmitters and neuroregulators in cerebral ischemia. This extraordinary work also covers aspects of protection against and resuscitation from cerebral ischemia. An extremely informative volume, this book is an absolute must for every student in the field of cerebral ischemia, as well as the clinician or scientist who is already involved with this worldwide problem.

The Newborn Brain

Author : Hugo Lagercrantz
Publisher : Cambridge University Press
Page : 427 pages
File Size : 43,6 Mb
Release : 2010-01-07
Category : Medical
ISBN : 9780521889759

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The Newborn Brain by Hugo Lagercrantz Pdf

The new edition of this respected work presents a comprehensive review of basic mechanisms of fetal and neonatal brain development.

Tissue Hypoxia and Ischemia

Author : Martin Reivich
Publisher : Springer Science & Business Media
Page : 382 pages
File Size : 52,8 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781461590354

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Tissue Hypoxia and Ischemia by Martin Reivich Pdf

This monograph contains the proceedings of a symposium entitled, "Tissue Hypoxia and Ischemia," which was held at the Annenberg Center of the University of Pennsylvania on August 13 and 14, 1976. The symposium was jointly sponsored by the following groups at the University of Pennsylvania: the Respiratory Physiology Group of the Department of Physio logy, the Cardiopulmonary Section of the Department of Medicine, the Johnson Research Foundation, the Cerebrovascular Research Center of the Department of Neurology, the Head Injury Center of the Department of Neurosurgery, the. Institute for Environ mental Medicine, and the International Society on Oxygen Transport to Tissues. Its purpose was to promote an interdisciplinary discussion of oxygen sensors in various tissues and their mechanism of action as well as to examine the deleterious effects of hypoxia and ischemia with special reference to the brain. There were four sessions, one on the biochemistry of physi ologic oxygen sensors, two on the mechanism of oxygen sensing in tissues and one on the circulatory and metabolic aspects of cerebral hypoxia and ischemia.

Fetal and Neonatal Brain Injury

Author : David K. Stevenson,William E. Benitz,Philip Sunshine,Susan R. Hintz,Maurice L. Druzin
Publisher : Cambridge University Press
Page : 855 pages
File Size : 47,7 Mb
Release : 2017-12-21
Category : Medical
ISBN : 9781107110809

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Fetal and Neonatal Brain Injury by David K. Stevenson,William E. Benitz,Philip Sunshine,Susan R. Hintz,Maurice L. Druzin Pdf

Authoritative, practical clinical text giving clear management advice on diagnosis, treatment and outcomes of all fetal and neonatal brain injuries.

Cardiopulmonary Critical Care

Author : David R. Dantzker
Publisher : Philadelphia : Saunders
Page : 888 pages
File Size : 48,6 Mb
Release : 1991
Category : Medical
ISBN : UOM:39015019841470

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Cardiopulmonary Critical Care by David R. Dantzker Pdf

Explores the spectrum of topics important to the treatment of critically ill patients with cardiac and respiratory failure, including in-depth discussions on pathophysiologic principles, approaches to therapy and individual disorders. Ethical and legal aspects are also considered.

Hypoxia and the Central Nervous System

Author : Charanjit Kaur
Publisher : Unknown
Page : 197 pages
File Size : 46,8 Mb
Release : 2007-01-01
Category : Anoxemia
ISBN : 8178952890

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Hypoxia and the Central Nervous System by Charanjit Kaur Pdf

Hypoxia-ischemia is an important and common cause of brain injury to the fetal and neonatal brain resulting in long term neurological deficits. In the adult, hypoxia, be it generalized or focal, is the most common pathological endpoint in a number of clinical conditions. Examples of these medical conditions include stroke, cardiac arrest, diseases of the respiratory system, carbon monoxide poisoning, asphyxia, brain trauma and tumors. Hypoxia also occurs when man challenges the environment and goes beyond the normal range of capabilities of the human body. Mountaineers, divers and aviators typically experience the effects of hypoxia associated with the extremes of such environments. Many of the mechanisms underlying the cellular responses are similar in the developing and adult brain. Cerebral hypoxia poses a challenge in terms of its pathological cascade, the adaptive responses and the possible protective mechanisms and therapeutic entities. This monograph is a collection of topics written by subject matter experts working on the various aspects of hypoxia with a particular emphasis on the developing central nervous system. The chapters range from a general introduction to various types of hypoxia followed by description of transcription factor activation, pathological changes, metabolism of iron in hypoxia, approaches to neuroprotection and finally stem cell therapy to combat hypoxic/ischemic injury. Researchers and clinicians will benefit from this treatise which begins with a general overview of hypoxia and goes on to the subtleties of the depth of research into this ubiquitous modality through which clinical and other effects manifest themselves.

Intensive Care in Childhood

Author : Dick Tibboel,Edwin van der Voort
Publisher : Springer Science & Business Media
Page : 553 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642802270

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Intensive Care in Childhood by Dick Tibboel,Edwin van der Voort Pdf

Intensive care in childhood is a relatively new field of medicine. Due to major differences in physiology, many disciplines are involved in the care of the critically ill child. Apart from specific disease patterns, morbidity in direct relation to the stay in the ICU or the underlying disease mainly determine long term morbidity. Today we understand that the treatment of the critically ill child can have a great impact on the quality of life in adulthood. This book covers the whole spectrum of intensive care in childhood. It is based on the experience of leading specialists from the various fields involved in the treatment of these children.