Synthetic Biology A Primer Revised Edition

Author : Paul S. FREEMONT,Richard I. KITNEY
Publisher : World Scientific
Page : 194 pages
File Size : 53,9 Mb
Release : 2015-08-24
Category : Science
ISBN : 9781783268801

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Synthetic Biology - a Primer (revised Edition) by Paul S. FREEMONT,Richard I. KITNEY Pdf

Synthetic Biology -- A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made.The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch exploring the fundamental basis of living systems.Examples of cutting-edge applications designed using synthetic biology principles are presented, including: The book also describes the Internationally Genetically Engineered Machine (iGEM) competition, which brings together students and young researchers from around the world to carry out summer projects in synthetic biology. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences into synthetic biology research.Final year undergraduates, postgraduates and established researchers interested in learning about the interdisciplinary field of synthetic biology will benefit from this up-to-date primer on synthetic biology.

Author : George M Church,Edward Regis
Publisher : Basic Books
Page : 305 pages
File Size : 43,7 Mb
Release : 2014-04-08
Category : Science
ISBN : 9780465038657

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Regenesis by George M Church,Edward Regis Pdf

A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

Author : R. I. Kitney
Publisher : Unknown
Page : 179 pages
File Size : 44,7 Mb
Release : 2012
Category : Synthetic biology
ISBN : 1848168640

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Synthetic Biology by R. I. Kitney Pdf

'Synthetic Biology' provides a broad overview of the emerging field of synthetic biology and the foundational concepts on which it is built. It will be of interest to final year undergraduates, postgraduates and established researchers who are interested in learning about this new field.

Author : Jim Haseloff,James Warren Ajioka,R. I. Kitney
Publisher : Unknown
Page : 176 pages
File Size : 54,5 Mb
Release : 2009
Category : Synthetic biology
ISBN : 0854037632

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Synthetic Biology by Jim Haseloff,James Warren Ajioka,R. I. Kitney Pdf

Author : Natalie Kuldell PhD.,Rachel Bernstein,Karen Ingram,Kathryn M Hart
Publisher : "O'Reilly Media, Inc."
Page : 238 pages
File Size : 54,9 Mb
Release : 2015-06-22
Category : Science
ISBN : 9781491907535

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BioBuilder by Natalie Kuldell PhD.,Rachel Bernstein,Karen Ingram,Kathryn M Hart Pdf

Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges. Learn the fundamentals of biodesign and DNA engineering Explore important ethical issues raised by examples of synthetic biology Investigate the BioBuilder labs that probe the design-build-test cycle Test synthetic living systems designed and built by engineers Measure several variants of an enzyme-generating genetic circuit Model "bacterial photography" that changes a strain’s light sensitivity Build living systems to produce purple or green pigment Optimize baker’s yeast to produce ?-carotene

Author : Basant K. Tiwary
Publisher : Springer Nature
Page : 239 pages
File Size : 55,9 Mb
Release : 2021-11-23
Category : Medical
ISBN : 9789811642418

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Bioinformatics and Computational Biology by Basant K. Tiwary Pdf

This textbook introduces fundamental concepts of bioinformatics and computational biology to the students and researchers in biology, medicine, veterinary science, agriculture, and bioengineering . The respective chapters provide detailed information on biological databases, sequence alignment, molecular evolution, next-generation sequencing, systems biology, and statistical computing using R. The book also presents a case-based discussion on clinical, veterinary, agricultural bioinformatics, and computational bioengineering for application-based learning in the respective fields. Further, it offers readers guidance on reconstructing and analysing biological networks and highlights computational methods used in systems medicine and genome-wide association mapping of diseases. Given its scope, this textbook offers an essential introductory book on bioinformatics and computational biology for undergraduate and graduate students in the life sciences, botany, zoology, physiology, biotechnology, bioinformatics, and genomic science as well as systems biology, bioengineering and the agricultural, and veterinary sciences.

Author : Frank H. Stephenson
Publisher : Academic Press
Page : 460 pages
File Size : 53,6 Mb
Release : 2010-07-30
Category : Science
ISBN : 012375691X

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Calculations for Molecular Biology and Biotechnology by Frank H. Stephenson Pdf

Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology. The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing. Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text New to this Edition: Updated and increased coverage of real time PCR and the mathematics used to measure gene expression More sample problems in every chapter for readers to practice concepts

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Publisher : National Academies Press
Page : 189 pages
File Size : 44,7 Mb
Release : 2019-01-05
Category : Technology & Engineering
ISBN : 9780309465182

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Biodefense in the Age of Synthetic Biology by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology Pdf

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Author : Kent H. Redford,William M. Adams
Publisher : Yale University Press
Page : 296 pages
File Size : 40,8 Mb
Release : 2021-06-22
Category : Nature
ISBN : 9780300230970

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Strange Natures by Kent H. Redford,William M. Adams Pdf

A groundbreaking examination of the implications of synthetic biology for biodiversity conservation Nature almost everywhere survives on human terms. The distinction between what is natural and what is human-made, which has informed conservation for centuries, has become blurred. When scientists can reshape genes more or less at will, what does it mean to conserve nature? The tools of synthetic biology are changing the way we answer that question. Gene editing technology is already transforming the agriculture and biotechnology industries. What happens if synthetic biology is also used in conservation to control invasive species, fight wildlife disease, or even bring extinct species back from the dead? Conservation scientist Kent Redford and geographer Bill Adams turn to synthetic biology, ecological restoration, political ecology, and de-extinction studies and propose a thoroughly innovative vision for protecting nature.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 49,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Robert H. Carlson
Publisher : Harvard University Press
Page : 290 pages
File Size : 47,5 Mb
Release : 2011-04-15
Category : Science
ISBN : 9780674053625

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Biology Is Technology by Robert H. Carlson Pdf

“Essential reading for anyone who wishes to understand the current state of biotechnology and the opportunities and dangers it may create.” —American Scientist Technology is a process and a body of knowledge as much as a collection of artifacts. Biology is no different—and we are just beginning to comprehend the challenges inherent in the next stage of biology as a human technology. It is this critical moment, with its wide-ranging implications, that Robert Carlson considers in Biology Is Technology. He offers a uniquely informed perspective on the endeavors that contribute to current progress in this area—the science of biological systems and the technology used to manipulate them. In a number of case studies, Carlson demonstrates that the development of new mathematical, computational, and laboratory tools will facilitate the engineering of biological artifacts—up to and including organisms and ecosystems. Exploring how this will happen, with reference to past technological advances, he explains how objects are constructed virtually, tested using sophisticated mathematical models, and finally constructed in the real world. Such rapid increases in the power, availability, and application of biotechnology raise obvious questions about who gets to use it, and to what end. Carlson’s thoughtful analysis offers rare insight into our choices about how to develop biological technologies and how these choices will determine the pace and effectiveness of innovation as a public good.

Author : Jeffrey Carl Braman
Publisher : Springer Nature
Page : 523 pages
File Size : 42,7 Mb
Release : 2024-06-02
Category : Electronic
ISBN : 9781071636589

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Synthetic Biology by Jeffrey Carl Braman Pdf

Author : Justin Pahara,Julie Legault
Publisher : Maker Media, Inc.
Page : 336 pages
File Size : 53,8 Mb
Release : 2021-08-19
Category : Science
ISBN : 9781680457674

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Zero to Genetic Engineering Hero by Justin Pahara,Julie Legault Pdf

Zero to Genetic Engineering Hero is made to provide you with a first glimpse of the inner-workings of a cell. It further focuses on skill-building for genetic engineering and the Biology-as-a-Technology mindset (BAAT). This book is designed and written for hands-on learners who have little knowledge of biology or genetic engineering. This book focuses on the reader mastering the necessary skills of genetic engineering while learning about cells and how they function. The goal of this book is to take you from no prior biology and genetic engineering knowledge toward a basic understanding of how a cell functions, and how they are engineered, all while building the skills needed to do so.

Author : Christina Smolke
Publisher : John Wiley & Sons
Page : 426 pages
File Size : 47,6 Mb
Release : 2018-06-05
Category : Science
ISBN : 9783527330751

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Synthetic Biology by Christina Smolke Pdf

A review of the interdisciplinary field of synthetic biology, from genome design to spatial engineering. Written by an international panel of experts, Synthetic Biology draws from various areas of research in biology and engineering and explores the current applications to provide an authoritative overview of this burgeoning field. The text reviews the synthesis of DNA and genome engineering and offers a discussion of the parts and devices that control protein expression and activity. The authors include information on the devices that support spatial engineering, RNA switches and explore the early applications of synthetic biology in protein synthesis, generation of pathway libraries, and immunotherapy. Filled with the most recent research, compelling discussions, and unique perspectives, Synthetic Biology offers an important resource for understanding how this new branch of science can improve on applications for industry or biological research.

Author : Madan L. Nagpal,Oana-Maria Boldura,Cornel Balta,Shymaa Enany
Publisher : BoD – Books on Demand
Page : 208 pages
File Size : 45,5 Mb
Release : 2020-02-12
Category : Medical
ISBN : 9781789840896

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Synthetic Biology by Madan L. Nagpal,Oana-Maria Boldura,Cornel Balta,Shymaa Enany Pdf

Synthetic biology gives us a new hope because it combines various disciplines, such as genetics, chemistry, biology, molecular sciences, and other disciplines, and gives rise to a novel interdisciplinary science. We can foresee the creation of the new world of vegetation, animals, and humans with the interdisciplinary system of biological sciences. These articles are contributed by renowned experts in their fields. The field of synthetic biology is growing exponentially and opening up new avenues in multidisciplinary approaches by bringing together theoretical and applied aspects of science.