Systemic Drug Delivery Strategies

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Systemic Drug Delivery Strategies

Mansoor M. Amiji,Lara Scheherazade Milane
Systemic Drug Delivery Strategies Book PDF

Author : Mansoor M. Amiji,Lara Scheherazade Milane
Publisher : Academic Press
Page : 590 pages
File Size : 55,5 Mb
Release : 2021-08-21
Category : Business & Economics
ISBN : 9780323909259

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Systemic Drug Delivery Strategies by Mansoor M. Amiji,Lara Scheherazade Milane Pdf

Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 examines the challenges of delivering immuno-oncology therapies, focusing specifically on the multiple technologies of affective drug delivery strategies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. This volume of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy discusses methods of targeting tumors, CRISPR technology, and vaccine delivery among many other delivery strategies. Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO

Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications

Wing-Fu Lai
Systemic Delivery Technologies in Anti Aging Medicine Methods and Applications Book PDF

Author : Wing-Fu Lai
Publisher : Springer Nature
Page : 511 pages
File Size : 44,5 Mb
Release : 2020-10-19
Category : Medical
ISBN : 9783030544904

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Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications by Wing-Fu Lai Pdf

This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development. There is a gap between basic aging research and the development of intervention technologies. This major obstacle must be overcome before biogerontological interventions can be put into clinical practice. As biogerontology comes to understand aging as a systemic degenerative process, it is clear that there is a pressing need for technologies that enable cells and tissues in a fully developed adult body to be manipulated systemically to combat aging. The authors review advances in the chemistry and engineering of systemic delivery methods and analyze the strengths and limitations of each. The book is organized into six sections. The first offers an overview of the need for systemic delivery technologies alongside the development of anti-aging therapies and describes approaches that will be required for studying the properties and efficiency of carriers for systemic delivery. Sections II, III and IV describe recent advances in a range of strategies that may enable systemic delivery to help combat aging conditions ranging from cell senescence to decline in immune function and hormonal secretion. Section V discusses practical strategies to engineer and optimize the performance of delivery technologies for applications in systemic delivery, along with their working principles. The final section discusses technical and biological barriers that must be overcome as systemic delivery technologies move from research laboratory to clinical applications aimed at tackling aging and age-associated diseases. Benefiting scholars, students and a broader audience of interested readers, the book includes helpful glossary sections in each chapter, as well as sidebars that highlight important notes, and questions for future research.

Advanced Drug Delivery Systems in the Management of Cancer

Kamal Dua,Meenu Mehta,Terezinha de Jesus Andreoli Pinto,Lisa G. Pont,Kylie A. Williams,Michael Rathbone
Advanced Drug Delivery Systems in the Management of Cancer Book PDF

Author : Kamal Dua,Meenu Mehta,Terezinha de Jesus Andreoli Pinto,Lisa G. Pont,Kylie A. Williams,Michael Rathbone
Publisher : Elsevier
Page : 572 pages
File Size : 54,6 Mb
Release : 2021-06-24
Category : Business & Economics
ISBN : 9780323900799

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Advanced Drug Delivery Systems in the Management of Cancer by Kamal Dua,Meenu Mehta,Terezinha de Jesus Andreoli Pinto,Lisa G. Pont,Kylie A. Williams,Michael Rathbone Pdf

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Nano Drug Delivery Strategies for the Treatment of Cancers

Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Nano Drug Delivery Strategies for the Treatment of Cancers Book PDF

Author : Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Publisher : Academic Press
Page : 374 pages
File Size : 54,6 Mb
Release : 2020-09-03
Category : Science
ISBN : 9780128197943

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Nano Drug Delivery Strategies for the Treatment of Cancers by Awesh K. Yadav,Umesh Gupta,Rajeev Sharma Pdf

Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles

Engineering Technologies and Clinical Translation

Mansoor M. Amiji,Lara Scheherazade Milane
Engineering Technologies and Clinical Translation Book PDF

Author : Mansoor M. Amiji,Lara Scheherazade Milane
Publisher : Academic Press
Page : 526 pages
File Size : 52,6 Mb
Release : 2021-08-25
Category : Business & Economics
ISBN : 9780323909501

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Engineering Technologies and Clinical Translation by Mansoor M. Amiji,Lara Scheherazade Milane Pdf

Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies, focusing specifically on the development of solutions for drug delivery and its clinical outcomes. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. This volume of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy discusses biomaterial, microfluidic, and biodegradable devices, engineered microbes, personalized medicine, clinical approval process, and many other IO technologies. Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Explores engineering technologies and their clinical translation in a comprehensive way Presents forecasting on the future of nanotechnology and drug delivery for IO Engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side

Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics

Alexandru Mihai Grumezescu
Multifunctional Systems for Combined Delivery Biosensing and Diagnostics Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 372 pages
File Size : 51,9 Mb
Release : 2017-05-03
Category : Technology & Engineering
ISBN : 9780323527262

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Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics by Alexandru Mihai Grumezescu Pdf

Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriented guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment. Explores the benefits of using a variety of nanomaterials as drug delivery agents Explains how nanocarriers can reduce the side effects of therapeutic agents Provides an analysis of the pros and cons of using specific nanocarriers to solve particular diagnosis and delivery problems

Drug Targeting and Stimuli Sensitive Drug Delivery Systems

Alexandru Mihai Grumezescu
Drug Targeting and Stimuli Sensitive Drug Delivery Systems Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 836 pages
File Size : 46,6 Mb
Release : 2018-05-21
Category : Science
ISBN : 9780128136904

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Drug Targeting and Stimuli Sensitive Drug Delivery Systems by Alexandru Mihai Grumezescu Pdf

Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy

Strategies to Modify the Drug Release from Pharmaceutical Systems

Marcos Luciano Bruschi
Strategies to Modify the Drug Release from Pharmaceutical Systems Book PDF

Author : Marcos Luciano Bruschi
Publisher : Woodhead Publishing
Page : 208 pages
File Size : 55,9 Mb
Release : 2015-06-16
Category : Medical
ISBN : 9780081001127

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Strategies to Modify the Drug Release from Pharmaceutical Systems by Marcos Luciano Bruschi Pdf

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. Addresses the principles, systems, applications and advances in the field of drug delivery Highlights the mathematical and physicochemical principles related to strategies Discusses drug release and its possible modifications

Modeling and Control of Drug Delivery Systems

Ahmad Taher Azar
Modeling and Control of Drug Delivery Systems Book PDF

Author : Ahmad Taher Azar
Publisher : Academic Press
Page : 410 pages
File Size : 54,9 Mb
Release : 2021-02-06
Category : Technology & Engineering
ISBN : 9780128211953

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Modeling and Control of Drug Delivery Systems by Ahmad Taher Azar Pdf

Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS

Drug Delivery Aspects

Ranjita Shegokar
Drug Delivery Aspects Book PDF

Author : Ranjita Shegokar
Publisher : Elsevier
Page : 266 pages
File Size : 43,9 Mb
Release : 2020-04-13
Category : Business & Economics
ISBN : 9780128212226

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Drug Delivery Aspects by Ranjita Shegokar Pdf

Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Encompasses engineering and large-scale manufacturing of nanocarriers Considers preclinical, regulatory and ethical guidelines on nanoparticles Contains in-depth discussions on delivery of biologics, vaccines and sterilisation Industrial view on solid dispersions, milling techniques

Controlled Drug Delivery

Kinam Park
Controlled Drug Delivery Book PDF

Author : Kinam Park
Publisher : Unknown
Page : 656 pages
File Size : 46,7 Mb
Release : 1997
Category : Medical
ISBN : UOM:39015040351143

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Controlled Drug Delivery by Kinam Park Pdf

This volume discusses the challenges of creating controlled release dosage forms that will deliver new therapeutic agents based on high-molecular-weight molecules. It examines strategies for delivering drugs through resistant biological barriers and surveys a variety of topics, including drug targeting, self-regulated drug delivery, protein drug delivery, biosensors, cell and tissue engineering, new biomaterials, modeling methods, pharmacokinetics, and U.S. federal regulations.

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

Prashant Kesharwani,Umesh Gupta
Nanotechnology Based Targeted Drug Delivery Systems for Brain Tumors Book PDF

Author : Prashant Kesharwani,Umesh Gupta
Publisher : Academic Press
Page : 478 pages
File Size : 49,5 Mb
Release : 2018-04-20
Category : Medical
ISBN : 9780128122495

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Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors by Prashant Kesharwani,Umesh Gupta Pdf

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors

Cancer Immunology and Immunotherapy

Mansoor M. Amiji,Lara Scheherazade Milane
Cancer Immunology and Immunotherapy Book PDF

Author : Mansoor M. Amiji,Lara Scheherazade Milane
Publisher : Academic Press
Page : 550 pages
File Size : 43,5 Mb
Release : 2021-08-18
Category : Business & Economics
ISBN : 9780128236376

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Cancer Immunology and Immunotherapy by Mansoor M. Amiji,Lara Scheherazade Milane Pdf

Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO

Pulmonary Drug Delivery

Ali Nokhodchi,Gary P. Martin
Pulmonary Drug Delivery Book PDF

Author : Ali Nokhodchi,Gary P. Martin
Publisher : John Wiley & Sons
Page : 391 pages
File Size : 49,5 Mb
Release : 2015-08-03
Category : Science
ISBN : 9781118799543

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Pulmonary Drug Delivery by Ali Nokhodchi,Gary P. Martin Pdf

Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

Smart Drug Delivery System

Ali Demir Sezer
Smart Drug Delivery System Book PDF

Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Page : 400 pages
File Size : 50,5 Mb
Release : 2016-02-10
Category : Medical
ISBN : 9789535122470

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Smart Drug Delivery System by Ali Demir Sezer Pdf

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.