Targeted Therapies For Solid Tumors

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Targeted Therapies for Solid Tumors

Antonio Russo,Rafael Rosell,Christian Rolfo
Targeted Therapies for Solid Tumors Book PDF

Author : Antonio Russo,Rafael Rosell,Christian Rolfo
Publisher : Humana Press
Page : 269 pages
File Size : 49,9 Mb
Release : 2015-03-11
Category : Medical
ISBN : 9781493920471

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Targeted Therapies for Solid Tumors by Antonio Russo,Rafael Rosell,Christian Rolfo Pdf

This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.

Targeted Therapies in Oncology

Giuseppe Giaccone,Jean-Charles Soria
Targeted Therapies in Oncology Book PDF

Author : Giuseppe Giaccone,Jean-Charles Soria
Publisher : CRC Press
Page : 498 pages
File Size : 44,9 Mb
Release : 2013-10-21
Category : Medical
ISBN : 9781842145463

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Targeted Therapies in Oncology by Giuseppe Giaccone,Jean-Charles Soria Pdf

Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edi

Molecularly Targeted Therapy for Childhood Cancer

Peter J. Houghton,Robert J. Arceci
Molecularly Targeted Therapy for Childhood Cancer Book PDF

Author : Peter J. Houghton,Robert J. Arceci
Publisher : Springer Science & Business Media
Page : 536 pages
File Size : 44,7 Mb
Release : 2010-09-10
Category : Medical
ISBN : 9780387690629

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Molecularly Targeted Therapy for Childhood Cancer by Peter J. Houghton,Robert J. Arceci Pdf

Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.

Handbook of Targeted Cancer Therapy and Immunotherapy

Daniel D. Karp,Gerald S. Falchook,JoAnn D. Lim
Handbook of Targeted Cancer Therapy and Immunotherapy Book PDF

Author : Daniel D. Karp,Gerald S. Falchook,JoAnn D. Lim
Publisher : Lippincott Williams & Wilkins
Page : 1277 pages
File Size : 45,8 Mb
Release : 2022-03-28
Category : Medical
ISBN : 9781975179267

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Handbook of Targeted Cancer Therapy and Immunotherapy by Daniel D. Karp,Gerald S. Falchook,JoAnn D. Lim Pdf

Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy, 3rd Edition, includes clinical trial results of more than 250 state-of-the-art targeted therapy and immunotherapy agents, providing a practical, intuitive, colorful overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Daniel D. Karp, Gerald S. Falchook, and JoAnn D. Lim, helps you navigate through the newest research reports and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of investigational targeted agents and combinations of agents. This handbook presents information distilled by dozens of translational research clinicians and other healthcare experts with hundreds of years of cumulative experience in the revolutionary area of genomically based precision oncology.

Targeted Therapy in Translational Cancer Research

Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson
Targeted Therapy in Translational Cancer Research Book PDF

Author : Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson
Publisher : John Wiley & Sons
Page : 320 pages
File Size : 52,8 Mb
Release : 2015-10-14
Category : Medical
ISBN : 9781118468661

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Targeted Therapy in Translational Cancer Research by Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson Pdf

Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities

Treating Cancer with Immunotherapy and Targeted Therapy

David A. Olle
Treating Cancer with Immunotherapy and Targeted Therapy Book PDF

Author : David A. Olle
Publisher : Mercury Learning and Information
Page : 235 pages
File Size : 45,6 Mb
Release : 2022-03-09
Category : Health & Fitness
ISBN : 9781683927525

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Treating Cancer with Immunotherapy and Targeted Therapy by David A. Olle Pdf

Treating cancer has always been a major challenge. Although great strides in treatment have taken place in recent years, all too often current treatments are less than effective, or patients relapse. Newer methods of cancer treatment, namely targeted therapy and immunotherapy have generated great excitement in the scientific community. These newer methods of cancer treatment hold promise for patients who otherwise may have few options. Using the principles of health literacy, this updated edition includes many new therapies and describes the essential features of cancer treatments available to the general public in an engaging and stimulating manner. A simple, question/answer format and the use of illustrations, tables, charts, and boxes that highlight definitions, facts, and website links provide more detailed information. Features: Provides questions and answers about the characteristics of cancer, diagnosis, classifications, surgery, chemotherapy, radiation therapy, targeted therapy, adoptive cell therapy, new developments, and more Cites many new therapies and includes numerous in-text Web links to information at the National Institutes of Health, the National Cancer Institute, journals, and other online sources Uses animations, practical tips, charts and tables, figures, and photos to explain topics under discussion.

Handbook of Targeted Cancer Therapy

Daniel D. Karp,Gerald S. Falchook
Handbook of Targeted Cancer Therapy Book PDF

Author : Daniel D. Karp,Gerald S. Falchook
Publisher : Lippincott Williams & Wilkins
Page : 288 pages
File Size : 50,9 Mb
Release : 2014-09-09
Category : Medical
ISBN : 9781469894584

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Handbook of Targeted Cancer Therapy by Daniel D. Karp,Gerald S. Falchook Pdf

Make optimal use of the latest personalized therapeutic strategies with Handbook of Targeted Cancer Therapy! This concise, practical oncology reference examines more than 140 targeted therapy agents for which clinical trial data are available, and explains when and how you can use them to most effectively combat cancer. Approach clinical challenges from any direction with separate sections on Targets by Organ Site, Carcinogenesis from the Perspective of Targeted Therapy, Molecular Targets and Pathways, and Targeted Therapy Agents. Find information easily thanks to a color-coded format and an intuitive organization. Access the complete contents online and on mobile devices, with regular updates to include newly approved treatments. Important state of the art cancer information for caregivers, researchers, other health care professionals, and even patients

Molecularly Targeted Therapy for Childhood Cancer

Peter J. Houghton,Robert J. Arceci
Molecularly Targeted Therapy for Childhood Cancer Book PDF

Author : Peter J. Houghton,Robert J. Arceci
Publisher : Springer
Page : 536 pages
File Size : 49,7 Mb
Release : 2010-09-08
Category : Medical
ISBN : 0387690603

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Molecularly Targeted Therapy for Childhood Cancer by Peter J. Houghton,Robert J. Arceci Pdf

Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.

A Beginner's Guide to Targeted Cancer Treatments

Elaine Vickers
A Beginner s Guide to Targeted Cancer Treatments Book PDF

Author : Elaine Vickers
Publisher : John Wiley & Sons
Page : 360 pages
File Size : 42,9 Mb
Release : 2018-05-08
Category : Medical
ISBN : 9781119126836

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A Beginner's Guide to Targeted Cancer Treatments by Elaine Vickers Pdf

The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon – terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live

Targeted Radionuclide Therapy

Tod W. Speer
Targeted Radionuclide Therapy Book PDF

Author : Tod W. Speer
Publisher : Lippincott Williams & Wilkins
Page : 564 pages
File Size : 40,6 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9781451153262

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Targeted Radionuclide Therapy by Tod W. Speer Pdf

Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Successes and Limitations of Targeted Cancer Therapy

S. Peters,R.A. Stahel
Successes and Limitations of Targeted Cancer Therapy Book PDF

Author : S. Peters,R.A. Stahel
Publisher : Karger Medical and Scientific Publishers
Page : 124 pages
File Size : 44,5 Mb
Release : 2014-02-19
Category : Medical
ISBN : 9783318025422

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Successes and Limitations of Targeted Cancer Therapy by S. Peters,R.A. Stahel Pdf

The treatment of patients with advanced malignancies has undergone remarkable change in the last few years. While in the past decisions about systemic therapy were largely based on the performance status of a patient, oncologists today also take into account the pathological and molecular characteristics of the patient’s tumor. Targeting specific molecular pathways important for tumorigenesis has become the preferred way of treatment for many types of malignancies. With these advances come new challenges including the optimization of therapy, recognizing and dealing with side effects and, importantly, the development of resistance. This book provides an up-to-date overview of the advances and limitations of targeted therapy for several tumor entities including breast cancer, colon cancer, gastrointestinal stromal tumors, lung cancer, melanoma, ovarian cancer and renal cell carcinoma. Written by over a dozen internationally renowned scientists, the book is suitable for advanced students, postdoctoral researchers, scientists and clinicians who wish to update their knowledge of the latest approaches to targeted cancer therapies.

Clinical Trials in Oncology, Third Edition

Stephanie Green,Jacqueline Benedetti,Angela Smith,John Crowley
Clinical Trials in Oncology Third Edition Book PDF

Author : Stephanie Green,Jacqueline Benedetti,Angela Smith,John Crowley
Publisher : CRC Press
Page : 266 pages
File Size : 48,8 Mb
Release : 2012-05-09
Category : Mathematics
ISBN : 9781439814482

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Clinical Trials in Oncology, Third Edition by Stephanie Green,Jacqueline Benedetti,Angela Smith,John Crowley Pdf

The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

Targeted Cancer Therapy

Razelle Kurzrock,Maurie Markman
Targeted Cancer Therapy Book PDF

Author : Razelle Kurzrock,Maurie Markman
Publisher : Springer Science & Business Media
Page : 446 pages
File Size : 50,6 Mb
Release : 2008-03-07
Category : Medical
ISBN : 9781603274241

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Targeted Cancer Therapy by Razelle Kurzrock,Maurie Markman Pdf

Emerging technologies in target identification, drug discovery, molecular markers, and imaging are rapidly changing the face of cancer. This book provides a foundation of knowledge in targeted cancer therapeutics. The treatment of cancer is increasingly being individualized, based on an understanding of underlying biologic mechanisms. Poised to change the landscape in oncology, this volume provides a state-of-the-art overview. It will be valuable to practicing and academic physicians, fellows, residents and students, as well as basic scientists, interested in the cancer field.

Cancer Consult: Expertise in Clinical Practice, Volume 1

Syed A. Abutalib,Maurie Markman,James O. Armitage,Kenneth C. Anderson,Hope S. Rugo,Al B. Benson, III
Cancer Consult Expertise in Clinical Practice Volume 1 Book PDF

Author : Syed A. Abutalib,Maurie Markman,James O. Armitage,Kenneth C. Anderson,Hope S. Rugo,Al B. Benson, III
Publisher : John Wiley & Sons
Page : 758 pages
File Size : 47,7 Mb
Release : 2023-11-14
Category : Medical
ISBN : 9781119823759

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Cancer Consult: Expertise in Clinical Practice, Volume 1 by Syed A. Abutalib,Maurie Markman,James O. Armitage,Kenneth C. Anderson,Hope S. Rugo,Al B. Benson, III Pdf

CANCER CONSULT New edition covering the specialties of hematology, oncology and cellular therapy, now in two volumes Cancer Consult: Expertise in Clinical Practice, Volume 1: Solid Tumors & Supportive Care, Second Edition includes hundreds of answers to practice-based questions covering the new principles of diagnosis, classification, staging, treatment, and outcomes in the rapidly advancing field of cancer. This textbook series also provides expert guidance in the areas of cancer-related uncertainties and controversies, including experience-based discussions. The book’s smaller size allows for easy access during medical rounds. This volume also includes: Up-to-date, clinically relevant information on the very latest topics such as molecular techniques, targeted therapies, immunotherapy, cellular therapy and translational cancer research Sections on head, neck, thoracic, breast, GI, genitourinary, skin, gynecological and hereditary cancers, amongst other topics Streamlined, engaging content to make finding information easier and less time consuming for the reader Concise and practical expert perspectives that reference key studies References to the latest NCCN, ESMO, ASCO, and other national guidelines With its powerful focus on pragmatic clinical diagnostic, therapeutic and prognostic approaches, Cancer Consult: Expertise in Clinical Practice, Volume 1: Solid Tumors & Supportive Care, Second Edition will help keep hematology, oncology and cellular therapy practitioners up-to-date, bridging the gaps between journal and reference literature, conferences, and their existing knowledge base. It also offers clinicians, trainees, and fellows an excellent opportunity to enhance their preparation for the ABIM, hematology and oncology fellowship and recertification exams.

Targeted Therapy for Solid Tumors and Hematologic Malignancies

Alfonso Quintás-Cardama,Don L. Gibbons,Vince Cataldo
Targeted Therapy for Solid Tumors and Hematologic Malignancies Book PDF

Author : Alfonso Quintás-Cardama,Don L. Gibbons,Vince Cataldo
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 2011
Category : Cancer
ISBN : 1617618543

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Targeted Therapy for Solid Tumors and Hematologic Malignancies by Alfonso Quintás-Cardama,Don L. Gibbons,Vince Cataldo Pdf

Endocrine malignancies are rare tumours that are derived from endocrine cells located throughout the body. They encompass a heterogeneous group of malignancies, derived from different endocrine and neuroendocrine cells and have different clinically. The majority of endocrine neoplasms are benign, where the potential for invasion or metastasis is very low. Nevertheless, there is a group of endocrine neoplasms with malignant potential, and thus come under the management of medical oncology, often requiring systemic therapy. These include neuroendocrine tumours, anaplastic and medullary thyroid carcinomas, pheochromocytomas or paragangliomas, and adrenocortical carcinomas. While surgery continues to play a seminal role, the management of advanced endocrine neoplasia is more complex due to their rarity and heterogeneity. This book discusses the use of targeted therapy in the treatment of solid tumours and hematologic malignancies.