The Antiphospholipid Syndrome

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Antiphospholipid Syndrome

Doruk Erkan,Michael D. Lockshin
Antiphospholipid Syndrome Book PDF

Author : Doruk Erkan,Michael D. Lockshin
Publisher : Springer
Page : 372 pages
File Size : 50,8 Mb
Release : 2017-06-09
Category : Medical
ISBN : 9783319554426

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Antiphospholipid Syndrome by Doruk Erkan,Michael D. Lockshin Pdf

This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.​​

Hughes Syndrome: The Antiphospholipid Syndrome

Graham Hughes,Shirish Sangle
Hughes Syndrome The Antiphospholipid Syndrome Book PDF

Author : Graham Hughes,Shirish Sangle
Publisher : Springer Science & Business Media
Page : 110 pages
File Size : 50,9 Mb
Release : 2011-11-19
Category : Medical
ISBN : 9780857297396

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Hughes Syndrome: The Antiphospholipid Syndrome by Graham Hughes,Shirish Sangle Pdf

Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students provides an in-depth analysis into the main effects of Hughes Syndrome. In 1983, Dr Graham Hughes, and his team in London, described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the Antiphospholipid Syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke and more importantly, it is treatable. Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students details the effects of Hughes Syndrome on the major organs, making it a valuable reference tool for students in training.

Hughes Syndrome

Munther A Khamashta
Hughes Syndrome Book PDF

Author : Munther A Khamashta
Publisher : Springer Science & Business Media
Page : 486 pages
File Size : 51,9 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9781447136668

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Hughes Syndrome by Munther A Khamashta Pdf

In 1983 Graham Hughes described a syndrome in which the blood has a tendency to clot. Hughes syndrome is at the root of diverse conditions such as stroke, leg vein thrombosis and recurrent abortion. Hughes Syndrome addresses the complete range of features produced by this common disorder, which is also known as antiphospholipid syndrome. The condition can affect any organ, and is treated using commonly available drugs including low-dose aspirin and warfarin. This timely book fulfils the need for a cross-disciplinary clinical textbook and contains contributions from the leading international authorities. Hughes Syndrome should be read by anyone who might have a clinical or scientific interest in this condition: rheumatologists, haematologists, obstetricians and neurologists.

The Antiphospholipid Syndrome

Ronald A. Asherson
The Antiphospholipid Syndrome Book PDF

Author : Ronald A. Asherson
Publisher : CRC Press
Page : 357 pages
File Size : 53,6 Mb
Release : 2018-05-04
Category : Medical
ISBN : 9781351085571

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The Antiphospholipid Syndrome by Ronald A. Asherson Pdf

Written by the foremost researchers in the field, this book gathers together in a single source the many important clinical associations of antiphospholipid antibodies. Antibody-related clotting mechanisms and their relationship to conditions such as recurrent strokes, chorea, multi infarct dementias, a variety of spinal syndromes, Addison's Disease, recurrent miscarriages, and many more are discussed in depth. The importance of these antibodies in 'Primary,' 'Secondary,' and 'Catastrophic' Antiphospholipid Syndrome is highlighted. Each chapter is devoted to a specific internal system and the clinical effects this syndrome has on that system. This authoritative book is an essential addition to medical libraries as well as an invaluable reference for general physicians, internists, rheumatologists, neurologists, cardiologists, nephrologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, and obstetricians.

Antiphospholipid Antibody Syndrome

Pier Luigi Meroni
Antiphospholipid Antibody Syndrome Book PDF

Author : Pier Luigi Meroni
Publisher : Springer
Page : 273 pages
File Size : 47,8 Mb
Release : 2014-11-20
Category : Medical
ISBN : 9783319110448

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Antiphospholipid Antibody Syndrome by Pier Luigi Meroni Pdf

This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

Antiphospholipid Syndrome

Doruk Erkan,Silvia S. Pierangeli
Antiphospholipid Syndrome Book PDF

Author : Doruk Erkan,Silvia S. Pierangeli
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 43,5 Mb
Release : 2012-05-19
Category : Medical
ISBN : 9781461431947

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Antiphospholipid Syndrome by Doruk Erkan,Silvia S. Pierangeli Pdf

The International Congress on Antiphospholipid Antibodies is held every three years to discuss the recent advances and future directions in Antiphospholipid Syndrome (APS). This volume collects the scientific highlights and new findings about APS that were generated from the most recent 13th Congress, held in Galveston, Texas in 2010. Chapters were written by an internationally-distinguished group of scientists from the point-of-view of multiple specialty areas. Each chapter was written in a uniform and systematic basis to present the latest evidence-based research, including the basic science of APS, task force reports from the Congress on controversial aspects of APS, and future directions of APS research. This book will appeal to all clinicians involved in the treatment and management of APS patients, to residents in a variety of medical subspecialties, and to research scientists interested in a better understanding of this complex and evolving disease.

Primary Antiphospholipid Syndrome

Antonio Serrano,Ricard Cervera,Jean-Christophe Raymond Gris
Primary Antiphospholipid Syndrome Book PDF

Author : Antonio Serrano,Ricard Cervera,Jean-Christophe Raymond Gris
Publisher : Unknown
Page : 0 pages
File Size : 53,8 Mb
Release : 2020
Category : Electronic
ISBN : OCLC:1368447335

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Primary Antiphospholipid Syndrome by Antonio Serrano,Ricard Cervera,Jean-Christophe Raymond Gris Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

The Antiphospholipid Syndrome

Ronald A. Asherson
The Antiphospholipid Syndrome Book PDF

Author : Ronald A. Asherson
Publisher : CRC Press
Page : 454 pages
File Size : 42,7 Mb
Release : 2018-05-04
Category : Medical
ISBN : 9781351094023

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The Antiphospholipid Syndrome by Ronald A. Asherson Pdf

Written by the foremost researchers in the field, this book gathers together in a single source the many important clinical associations of antiphospholipid antibodies. Antibody-related clotting mechanisms and their relationship to conditions such as recurrent strokes, chorea, multi infarct dementias, a variety of spinal syndromes, Addison's Disease, recurrent miscarriages, and many more are discussed in depth. The importance of these antibodies in 'Primary,' 'Secondary,' and 'Catastrophic' Antiphospholipid Syndrome is highlighted. Each chapter is devoted to a specific internal system and the clinical effects this syndrome has on that system. This authoritative book is an essential addition to medical libraries as well as an invaluable reference for general physicians, internists, rheumatologists, neurologists, cardiologists, nephrologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, and obstetricians.

Positive Options for Antiphospholipid Syndrome (APS)

Triona Holden
Positive Options for Antiphospholipid Syndrome APS Book PDF

Author : Triona Holden
Publisher : Turner Publishing Company
Page : 158 pages
File Size : 49,7 Mb
Release : 2003-08-01
Category : Health & Fitness
ISBN : 9781630265502

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Positive Options for Antiphospholipid Syndrome (APS) by Triona Holden Pdf

This book contains information on an increasingly common autoimmune disorder. Also called "sticky blood" and Hughes Syndrome, APS makes one's blood clot too easily, creating high risk of stroke, thrombosis, and premature heart attack. It is also implicated in many other health problems including repeated miscarriages, neurological problems, eary dementia and migraines. It is often associated with lupus, and mimics the symptoms of other diseases, including MS. Symptoms include; migraines and headaches, recurrent miscarriage, memory loss, slurred speech, blood clots, poor circulation, muscle pain and cramps, blurred vision, extreme fatigue, epilepsy, strokes, thrombosis and a form of angina. Because of lack of knowledge of APS in the medical establishment, sufferers are often misdiagnosed with MS or other more life-threatening conditions. This book helps the reader identify the symptoms and provides important information on diagnosis and treatment of APS. It contains many moving stories, explaining how people eventually got a diagnosis, their symptoms, the impact of APS on their lives and whether or not treatment has worked. Written in collaboration with Dr. Graham Hughes, the major researcher of APS in the UK, this book provides a clearly written informative look at an important but little-known disease.

Evidence-based Obstetrics and Gynecology

Errol R. Norwitz,Carolyn M. Zelop,David A. Miller,David L. Keefe
Evidence based Obstetrics and Gynecology Book PDF

Author : Errol R. Norwitz,Carolyn M. Zelop,David A. Miller,David L. Keefe
Publisher : John Wiley & Sons
Page : 646 pages
File Size : 55,6 Mb
Release : 2019-02-26
Category : Medical
ISBN : 9781444334333

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Evidence-based Obstetrics and Gynecology by Errol R. Norwitz,Carolyn M. Zelop,David A. Miller,David L. Keefe Pdf

The most comprehensive evidence-based guide to both obstetrics and gynecology Aimed at practicing obstetricians, gynecologists, and trainees in the specialty, Evidence-based Obstetrics and Gynecology concentrates on the clinical practice areas of diagnosis, investigation and management. The first section of the book discusses evidence-based medicine methodology in the context of the two specialties. The second and third sections cover all the major conditions in obstetrics and gynecology, with each chapter reviewing the best available evidence for management of the particular condition. The chapters are structured in line with EBM methodology, meaning the cases generate the relevant clinical questions. Evidence-based Obstetrics and Gynecology provides in-depth chapter coverage of abnormal vaginal bleeding; ectopic pregnancy; pelvic pain; lower genital tract infections; contraception and sterilization; breast diseases; urogynecology; endocrinology and infertility; puberty and precocious puberty; cervical dysplasia and HPV; cervical, vaginal, vulvar, uterine, and ovarian cancer; preconception care; prenatal care and diagnosis; drugs and medications in pregnancy; maternal complications; chronic hypertension; diabetes mellitus; thyroid disease; neurologic disease; psychiatric disease; postterm pregnancy; fetal complications; preeclampsia; and more. First book to address evidence-based practice for obstetrics and gynecology combined EBM is a highly relevant approach for this high risk specialty Edited by leading US specialist involved in the evidence-based medicine movement Evidence-Based Obstetrics and Gynecology is an important text for obstetricians and gynecologists in practice and in training, as well as for specialist nurses.

Inpatient Dermatology

Misha Rosenbach,Karolyn A. Wanat,Robert G. Micheletti,Laura A. Taylor
Inpatient Dermatology Book PDF

Author : Misha Rosenbach,Karolyn A. Wanat,Robert G. Micheletti,Laura A. Taylor
Publisher : Springer
Page : 415 pages
File Size : 47,7 Mb
Release : 2018-11-03
Category : Medical
ISBN : 9783319184494

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Inpatient Dermatology by Misha Rosenbach,Karolyn A. Wanat,Robert G. Micheletti,Laura A. Taylor Pdf

​​​ Inpatient Dermatology is a concise and portable resource that synthesizes the most essential material to help physicians with recognition, differential diagnosis, work-up, and treatment of dermatologic issues in the hospitalized patient. Complete with hundreds of clinical and pathologic images, this volume is both an inpatient dermatology atlas and a practical guide to day-one, initial work-up, and management plan for common and rare skin diseases that occur in the inpatient setting. Each chapter is a bulleted, easy-to-read reference that focuses on one specific inpatient dermatologic condition, with carefully curated clinical photographs and corresponding histopathologic images to aid readers in developing clinical-pathologic correlation for the dermatologic diseases encountered in the hospital. Before each subsection the editors share diagnostic pearls, explaining their approach to these challenging conditions. This book is structured to be useful to physicians, residents, and medical students. It spans dermatology, emergency medicine, internal medicine, infectious disease, and rheumatology. Inpatient Dermatology is the go-to guide for hospital-based skin diseases, making even the most complex inpatient dermatologic issues approachable and understandable for any clinician.

The Antiphospholipid Syndrome II

R. Cervera,J.C. Piette,Yehuda Shoenfeld
The Antiphospholipid Syndrome II Book PDF

Author : R. Cervera,J.C. Piette,Yehuda Shoenfeld
Publisher : Elsevier
Page : 478 pages
File Size : 51,7 Mb
Release : 2002-08-22
Category : Medical
ISBN : 0080527302

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The Antiphospholipid Syndrome II by R. Cervera,J.C. Piette,Yehuda Shoenfeld Pdf

This book provides the reader with a comprehensive overview of the Antiphospholipid syndrome. One of the most important advances in rheumatology and connective tissue diseases of the last decade. It provides an explanation for many previously undefined conditions with no clear pathogenesis encompassing all subspeculations in internal medicine as well as obstetrics. Clotting problems leading to strokes and myocardial infarctions (in younger people) as well as a large variety of other syndromes such as chorea, hyproadrenalism, pulmonary problems are now being understood.

Dubois' Lupus Erythematosus and Related Syndromes - E-Book

Daniel Wallace,Bevra Hannahs Hahn
Dubois Lupus Erythematosus and Related Syndromes E Book Book PDF

Author : Daniel Wallace,Bevra Hannahs Hahn
Publisher : Elsevier Health Sciences
Page : 752 pages
File Size : 44,9 Mb
Release : 2018-08-16
Category : Medical
ISBN : 9780323550642

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Dubois' Lupus Erythematosus and Related Syndromes - E-Book by Daniel Wallace,Bevra Hannahs Hahn Pdf

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes. Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients. Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS). Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment. Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.

Vaccines and Autoimmunity

Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic
Vaccines and Autoimmunity Book PDF

Author : Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic
Publisher : John Wiley & Sons
Page : 394 pages
File Size : 50,6 Mb
Release : 2015-07-07
Category : Science
ISBN : 9781118663431

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Vaccines and Autoimmunity by Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic Pdf

In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

Understanding Hughes Syndrome

Graham Hughes
Understanding Hughes Syndrome Book PDF

Author : Graham Hughes
Publisher : Springer Science & Business Media
Page : 132 pages
File Size : 47,8 Mb
Release : 2010-01-23
Category : Medical
ISBN : 9781848003767

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Understanding Hughes Syndrome by Graham Hughes Pdf

Along with AIDS, antiphospholipid syndrome was the major medical discovery of the late 20th century, so for many it is still deemed a ‘new’ disease. The discovery of ‘sticky blood’ (commonly known as antiphospholipid syndrome or ‘Hughes Syndrome’) came out of years of observation of patients who had developed lupus. Many specialists in the 1970s were interested in the neurological aspects of lupus, and Dr Hughes, among others, spent a number of years studying the mechanisms of brain inflammation. In the mid 1970s, Hughes observed a number of young women with a form of viral paralysis, where interestingly many of them carried an antibody in their blood actually directed against ‘phospholipid’ – one of the components of brain and spinal cord. It quickly became apparent that individuals who had "anti-phospholipid antibodies" suffered from a tendency not only to develop brain and spinal cord symptoms, but also a tendency to develop both vein and artery thrombosis. As investigation continued it became apparent that these symptoms were not just confined to lupus patients, but occurred in others too, specifically those with severe migraines, with repeated strokes, with memory loss, and in women with recurrent miscarriage.