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The monetization of medicine is merely in its cradle. - Ronit Arora, CEO, Meridian Labs In Frankfurt, an affluent heir faces his nemesis ten years after a miraculous cure. In Kolkata, an eminent NGO doctors the health records of unwitting sex workers. In cyberspace, an invisible army distorts consumers’ reality. And in Mumbai, biotechnologist Shubhra Sen connects the dots through ‘The Aquila Trials.’ In the maze of a clinical trial gone awry, Shubhra is set against an opponent who will stop at nothing to rise to the echelons of the Global Billionaire CEO Club. A kaleidoscopic perspective on pharmacracy lays bare the commercialization, politicization, and ritualization of medicine. Pitting the strategies of Chanakya against those of Sun Tzu, communications specialist Kruti Shah unfolds a story of Big Pharma greed, corporate arm-twisting, and thrill.
The L’Aquila Trial Revisited by Massimiliano Stucchi,Rui Pinho,Massimo Cocco Pdf
This book summarizes and critically reviews the complex story of the L’Aquila trial, in which five scientists and two civil protection officers were prosecuted for manslaughter after the earthquake of 6 April 2009 and sentenced to six-year terms in jail plus the payment of approximately 7 million euros to relatives of the victims. The aim is to cast light on the many open questions and inconsistencies in the reporting of the trial, as well as to examine the trial’s implications and consequences. The seismological evidence and the knowledge of earthquake risk in the L’Aquila region before the earthquake are first reviewed. Key events, including the meeting attended by the defendants on 31 March 2009 and the interview recorded before but broadcast after the meeting, are carefully analyzed. The material presented by the prosecution and defence and the reasoning of the judge in reaching his verdict are then discussed, with detailed examination of the scientific issues relevant to the sentence. Although six of the defendants were acquitted upon appeal, and the sentence of the seventh was reduced, the trial remains a landmark event. Many readers will find that this book causes them to reconsider their opinions of the original trial.
Innovative Internet Computing Systems by Herwig Unger,Thomas Boehme,Armin Mikler Pdf
This book constitutes the refereed proceedings of the second international workshop on Innovative Internet Computing Systems, IICS 2002, held in Khlungsborn, Germany, in June 2002. The 19 revised full papers presented together with an invited paper were carefully reviewed and selected from over 30 submissions. Among the topics addressed are large-scale distributed computing infrastructures presenting new challenges to information and Web technology, the management and retrieval of web-based information, content classification, web-based communities management, structure and retrieval of information from large distributed data bases, and the representation of the distributed nature of information by means of graph-theoretical models.
Cultural Expertise and Socio-Legal Studies by Austin Sarat Pdf
In this special issue, socio-legal scientists with interdisciplinary backgrounds scrutinize the applicability of the notion of cultural expertise in Europe and the rest of the World. Cases include murder, female genital mutilation, earthquake claims, Islamic law, underage marriages, child custody, adoption, land rights, and asylum.
Evolutionary Trends of the Internet by Sergio Palazzo Pdf
This book constitutes the refereed proceedings of the Thyrrhenian International Workshop on Digital Communication, IWDC 2001, held in Taormina, Italy in September 2001. The 46 revised full papers presented are a mix of invited papers and selected submitted papers and reflect the state of the art in multiservice IP network research and development. The book offers topical sections on WDM technologies for the next generation Internet, mobile and wireless Internet access, QoS in the next generation Internet, multicast and routing in IP networks, mulitmedia services over the Internet, performance of Internet protocols, dynamic service management, and source encoding and Internet applications.
Trust Matters by Raquel Barradas de Freitas,Sergio Lo Iacono Pdf
This book examines the role of trust in public life. It seeks to contribute to a more nuanced understanding of certain fundamental concepts in political and legal theory, such as the concepts of authority, power, social practice, the rule of law, and justice by furnishing and sharpening our concepts of trust and trustworthiness. Bringing together contributors from across the social, cognitive, historical, and political sciences, the book opens up inquiries into central concepts in legal theory as well as new approaches and methodologies. The interdisciplinary contributions analyse the notions of trust, trustworthiness, and distrust and apply them to address a variety of problems and questions.
Ethics and Law for Chemical, Biological, Radiological, Nuclear & Explosive Crises by Dónal P. O'Mathúna,Iñigo de Miguel Beriain Pdf
This book provides a current analysis of the legal and ethical challenges in preparing for and responding to chemical, biological, radiological, nuclear and explosive (CBRNE) crises. From past events like the Chernobyl nuclear incident in Russia or the Bhopal chemical calamity in India, to the more recent tsunami and nuclear accident in Japan or the Ebola crisis in Africa, and with the on-going threat of bioterrorism, the need to be ready to respond to CBRNE crises is uncontroversial. What is controversial is whether we are on a path that adequately prepares us for the next event. The ethical and legal scholars in this volume hold that much work remains to be done and offer this book to stimulate further reflection and dialogue around CBRNE crises. This is an indispensable book for both students and scholars of bioethics, international law, public health, as well as for regulators and administrators developing policy and legislation related to public health planning and emergency responses.
Nevirapine and the Quest to End Pediatric AIDS by Rebecca J. Anderson Pdf
In 1999, investigators announced that a single dose of nevirapine, a new antiviral drug, could stop the spread of the AIDS virus from infected mothers to their newborn babies. It was a discovery that "changed the face of AIDS globally" but it came at a high price, after years of scientific research, political conflict, social unrest and the loss of many thousands of lives. This book is the historical account of pediatric AIDS from the first reported cases in the early 1980s to the first effective treatments in the 1990s and then to the prevention of HIV infections altogether. It also includes the firsthand accounts and experiences of children infected with HIV, their families and the physicians who treated them, as well as the scientists who sought to understand the virus, discovered nevirapine's unique properties, and worked tirelessly to get it to the patients who needed it.
Methods and Applications of Statistics in Clinical Trials, Volume 1 by N. Balakrishnan Pdf
A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results. The referenceunveils modern approaches vital to understanding, creating, and evaluating data obtained throughoutthe various stages of clinical trial design and analysis. Accessible and comprehensive, the first volume in a two-part set includes newly-written articles as well as established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: Detailed chapters on the type of trial designs, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials Over 100 contributions from leading academics, researchers, and practitioners An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.
Edited by two experts in the area, Geoethics: Ethical Challenges and Case Studies in Earth Sciences addresses a range of topics surrounding the concept of ethics in geoscience, making it an important reference for any Earth scientist with a growing concern for sustainable development and social responsibility. This book will provide the reader with some obvious and some hidden information you need for understanding where experts have not served the public, what more could have been done to reach and serve the public and the ethical issues surrounding the Earth Sciences, from a global perspective. Written by a global group of contributors with backgrounds ranging from philosopher to geo-practitioner, providing a balance of voices Includes case studies, showing where experts have gone wrong and where key organizations have ignored facts, wanting assessments favorable to their agendas Provides a much needed basis for discussion to guide scientists to consider their responsibilities and to improve communication with the public
