The Central Role Of The Propensity Score In Observational Studies For Causal Effects
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The Central Role of the Propensity Score in Observational Studies for Causal Effects by Paul R. Rosenbaum,Donald B. Rubin Pdf
The results of observational studies are often disputed because of nonrandom treatment assignment. For example, patients at greater risk may be overrepresented in some treatment group. This paper discusses the central role of propensity scores and balancing scores in the analysis of observational studies. The propensity score is the (estimated) conditional probability of assignment to a particular treatment given a vector of observed covariates. Both large and small sample theory show that adjustment for the scalar propensity score is sufficient to remove bias due to all observed covariates. Applications include: matched sampling on the univariate propensity score which is equal percent bias reducing under more general conditions than required for discriminant matching, multivariate adjustment by subclassification on balancing scores where the same subclasses are used to estimate treatment effects for all outcome variables and in all subpopulations, and visual representation of multivariate adjustment by a two-dimensional plot. (Author).
Propensity Score Analysis by Shenyang Guo,Mark W. Fraser Pdf
Provides readers with a systematic review of the origins, history, and statistical foundations of Propensity Score Analysis (PSA) and illustrates how it can be used for solving evaluation and causal-inference problems.
Propensity Score Analysis by Wei Pan,Haiyan Bai Pdf
This book is designed to help researchers better design and analyze observational data from quasi-experimental studies and improve the validity of research on causal claims. It provides clear guidance on the use of different propensity score analysis (PSA) methods, from the fundamentals to complex, cutting-edge techniques. Experts in the field introduce underlying concepts and current issues and review relevant software programs for PSA. The book addresses the steps in propensity score estimation, including the use of generalized boosted models, how to identify which matching methods work best with specific types of data, and the evaluation of balance results on key background covariates after matching. Also covered are applications of PSA with complex data, working with missing data, controlling for unobserved confounding, and the extension of PSA to prognostic score analysis for causal inference. User-friendly features include statistical program codes and application examples. Data and software code for the examples are available at the companion website (www.guilford.com/pan-materials).
Matched Sampling for Causal Effects by Donald B. Rubin Pdf
Matched sampling is often used to help assess the causal effect of some exposure or intervention, typically when randomized experiments are not available or cannot be conducted. This book presents a selection of Donald B. Rubin's research articles on matched sampling, from the early 1970s, when the author was one of the major researchers involved in establishing the field, to recent contributions to this now extremely active area. The articles include fundamental theoretical studies that have become classics, important extensions, and real applications that range from breast cancer treatments to tobacco litigation to studies of criminal tendencies. They are organized into seven parts, each with an introduction by the author that provides historical and personal context and discusses the relevance of the work today. A concluding essay offers advice to investigators designing observational studies. The book provides an accessible introduction to the study of matched sampling and will be an indispensable reference for students and researchers.
Agency for Health Care Research and Quality (U.S.)
Author : Agency for Health Care Research and Quality (U.S.) Publisher : Government Printing Office Page : 204 pages File Size : 40,6 Mb Release : 2013-02-21 Category : Medical ISBN : 9781587634239
Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by Agency for Health Care Research and Quality (U.S.) Pdf
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
The Reviewer’s Guide to Quantitative Methods in the Social Sciences by Gregory R. Hancock,Ralph O. Mueller,Laura M. Stapleton Pdf
Designed for reviewers of research manuscripts and proposals in the social and behavioral sciences, and beyond, this title includes chapters that address traditional and emerging quantitative methods of data analysis.
Econometric Evaluation of Labour Market Policies by Michael Lechner,Friedhelm Pfeiffer Pdf
Empirical measurement of impacts of active labour market programmes has started to become a central task of economic researchers. New improved econometric methods have been developed that will probably influence future empirical work in various other fields of economics as well. This volume contains a selection of original papers from leading experts, among them James J. Heckman, Noble Prize Winner 2000 in economics, addressing these econometric issues at the theoretical and empirical level. The theoretical part contains papers on tight bounds of average treatment effects, instrumental variables estimators, impact measurement with multiple programme options and statistical profiling. The empirical part provides the reader with econometric evaluations of active labour market programmes in Canada, Germany, France, Italy, Slovak Republic and Sweden.
Selected Statistical Papers of Sir David Cox: Volume 2, Foundations of Statistical Inference, Theoretical Statistics, Time Series and Stochastic Processes by David Roxbee Cox Pdf
Sir David Cox's most important papers, each the subject of a new commentary by Professor Cox.
This collection of intriguing essays describes important applications of statistics and probability in many fields. Instead of teaching methods, the essays illustrate past accomplishments and current uses of statistics and probability. Surveys, questionnaires, experiments, and observational studies are also presented to help the student better understand the importance of the influence of statistics on each topic covered within the separate essays. The overarching goal of STATISTICS: A GUIDE TO THE UNKNOWN is to demonstrate the wide use and importance of statistics through an integrated set of case studies that are readable, interesting, and meaningful to the general public.
Author : J. Michael Oakes,Jay S. Kaufman Publisher : John Wiley & Sons Page : 507 pages File Size : 41,7 Mb Release : 2006-05-11 Category : Medical ISBN : 0787985945
Methods in Social Epidemiology by J. Michael Oakes,Jay S. Kaufman Pdf
Social epidemiology is the study of how social interactions—social norms, laws, institutions, conventia, social conditions and behavior—affect the health of populations. This practical, comprehensive introduction to methods in social epidemiology is written by experts in the field. It is perfectly timed for the growth in interest among those in public health, community health, preventive medicine, sociology, political science, social work, and other areas of social research. Topics covered are: Introduction: Advancing Methods in Social Epidemiology The History of Methods of Social Epidemilogy to 1965 Indicators of Socioeconomic Position Measuring and Analyzing 'Race' Racism and Racial Discrimination Measuring Poverty Measuring Health Inequalities A Conceptual Framework for Measuring Segregation and its Association with Population Outcomes Measures of Residential Community Contexts Using Census Data to Approximate Neighborhood Effects Community-based Participatory Research: Rationale and Relevance for Social Epidemiology Network Methods in Social Epidemiology Identifying Social Interactions: A Review, Multilevel Studies Experimental Social Epidemiology: Controlled Community Trials Propensity Score Matching Methods for Social Epidemiology Natural Experiments and Instrumental Variable Analyses in Social Epidemiology and Using Causal Diagrams to Understand Common Problems in Social Epidemiology. "Publication of this highly informative textbook clearly reflects the coming of age of many social epidemiology methods, the importance of which rests on their potential contribution to significantly improving the effectiveness of the population-based approach to prevention. This book should be of great interest not only to more advanced epidemiology students but also to epidemiologists in general, particularly those concerned with health policy and the translation of epidemiologic findings into public health practice. The cause of achieving a ‘more complete’ epidemiology envisaged by the editors has been significantly advanced by this excellent textbook." —Moyses Szklo, professor of epidemiology and editor-in-chief, American Journal of Epidemiology, Johns Hopkins University "Social epidemiology is a comparatively new field of inquiry that seeks to describe and explain the social and geographic distribution of health and of the determinants of health. This book considers the major methodological challenges facing this important field. Its chapters, written by experts in a variety of disciplines, are most often authoritative, typically provocative, and often debatable, but always worth reading." —Stephen W. Raudenbush, Lewis-Sebring Distinguished Service Professor, Department of Sociology, University of Chicago "The roadmap for a new generation of social epidemiologists. The publication of this treatise is a significant event in the history of the discipline." —Ichiro Kawachi, professor of social epidemiology, Department of Society, Human Development, and Health, Harvard University "Methods in Social Epidemiology not only illuminates the difficult questions that future generations of social epidemiologists must ask, it also identifies the paths they must boldly travel in the pursuit of answers, if this exciting interdisciplinary science is to realize its full potential. This beautifully edited volume appears at just the right moment to exert a profound influence on the field." —Sherman A. James, Susan B. King Professor of Public Policy Studies, professor of Community and Family Medicine, professor of African-American Studies, Duke University
Secondary Analysis of Electronic Health Records by MIT Critical Data Pdf
This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.
Specially selected from The New Palgrave Dictionary of Economics 2nd edition, each article within this compendium covers the fundamental themes within the discipline and is written by a leading practitioner in the field. A handy reference tool.
An observational study is an empirical investigation of the effects of treatments, policies, or exposures. It differes from an experiment in that the investigator cannot control the assignments of treatments to subjects. Scientists across a wide range of disciplines undertake such studies, and the aim of this book is to provide a sound statistical account of the principles and methods for the design and analysis of observational studies. Readers are assumed to have a working knowledge of basic probability and statistics, but otherwise the account is reasonably self-contained. Throughout there are extended discussions of actual observational studies to illustrate the ideas discussed. These are drawn from topics as diverse as smoking and lung cancer, lead in children, nuclear weapons testing, and placement programs for students. As a result, many researchers involved in observational studes will find this an invaluable companion to their work.
Alina A. von Davier,Paul W. Holland,Dorothy T. Thayer
Author : Alina A. von Davier,Paul W. Holland,Dorothy T. Thayer Publisher : Springer Science & Business Media Page : 244 pages File Size : 45,9 Mb Release : 2003-10-01 Category : Business & Economics ISBN : 9780387019857
The Kernel Method of Test Equating by Alina A. von Davier,Paul W. Holland,Dorothy T. Thayer Pdf
KE is applied to the four major equating designs and to both Chain Equating and Post-Stratification Equating for the Non-Equivalent groups with Anchor Test Design. It will be an important reference for several groups: (a) Statisticians (b) Practitioners and (c) Instructors in psychometric and measurement programs. The authors assume some familiarity with linear and equipercentile test equating, and with matrix algebra.
Applied Bayesian Modeling and Causal Inference from Incomplete-Data Perspectives by Andrew Gelman,Xiao-Li Meng Pdf
This book brings together a collection of articles on statistical methods relating to missing data analysis, including multiple imputation, propensity scores, instrumental variables, and Bayesian inference. Covering new research topics and real-world examples which do not feature in many standard texts. The book is dedicated to Professor Don Rubin (Harvard). Don Rubin has made fundamental contributions to the study of missing data. Key features of the book include: Comprehensive coverage of an imporant area for both research and applications. Adopts a pragmatic approach to describing a wide range of intermediate and advanced statistical techniques. Covers key topics such as multiple imputation, propensity scores, instrumental variables and Bayesian inference. Includes a number of applications from the social and health sciences. Edited and authored by highly respected researchers in the area.