The Discovery Of Bioactive Natural Products The Isolation And Structural Elucidation Genome Mining Osmac Strategy And Biotransformation

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The discovery of bioactive natural products: The isolation and structural elucidation, genome mining, OSMAC strategy, and biotransformation

Author : Ling Liu,Dewu Zhang,Fushuang Li,Kalindi Morgan
Publisher : Frontiers Media SA
Page : 161 pages
File Size : 55,7 Mb
Release : 2023-08-30
Category : Science
ISBN : 9782832532751

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The discovery of bioactive natural products: The isolation and structural elucidation, genome mining, OSMAC strategy, and biotransformation by Ling Liu,Dewu Zhang,Fushuang Li,Kalindi Morgan Pdf

Bioactive Molecules from Marine Microorganisms

Author : Hanna Mazur-Marzec,Anna Toruńska-Sitarz
Publisher : Unknown
Page : 172 pages
File Size : 41,7 Mb
Release : 2021
Category : Electronic
ISBN : 3036506217

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Bioactive Molecules from Marine Microorganisms by Hanna Mazur-Marzec,Anna Toruńska-Sitarz Pdf

For this Special Issue book, ten papers focusing on novel bioactive molecules from different marine microorganisms, including fungi, cyanobacteria, actinobacteria and diatoms, were selected. The isolated biomolecules represent different structures and showed anticancer, antiviral, antifungal, antibacterial, anti-inflammatory and enzyme-inhibiting activities. One of the papers is a review article on microviridins, a class of bioactive cyanobacterial peptides.

Natural Bioactive Products in Sustainable Agriculture

Author : Joginder Singh,Ajar Nath Yadav
Publisher : Springer Nature
Page : 307 pages
File Size : 51,6 Mb
Release : 2020-05-11
Category : Medical
ISBN : 9789811530241

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Natural Bioactive Products in Sustainable Agriculture by Joginder Singh,Ajar Nath Yadav Pdf

This book discusses various aspects of bioactive natural products employed in the agrochemical and agriculture sectors. It covers the use of plants, microorganisms, and microbial metabolites as eco-friendly, cost-effective, and sustainable alternatives to chemicals in the field of agriculture. Written by active researchers and academics, the book highlights state-of-art products in the field, as well as the gaps, challenges, and obstacles associated with the use of plants, microbes and their products. Given its scope, it is a valuable resource for the scientific community and professionals in enterprises wanting insights into the latest developments and advances in the context of biological products, including their applications, traditional uses, modern practices, and strategies to harness their full potential.

Microbial Bioenergetics

Author : Davide Zannoni,Fevzi Daldal,Wolfgang Nitschke,Catarina M. Paquete
Publisher : Frontiers Media SA
Page : 215 pages
File Size : 54,6 Mb
Release : 2022-01-17
Category : Science
ISBN : 9782889740420

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Microbial Bioenergetics by Davide Zannoni,Fevzi Daldal,Wolfgang Nitschke,Catarina M. Paquete Pdf

Progress in the Chemistry of Organic Natural Products 108

Author : A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi,Yoshinori Asakawa,Ji-Kai Liu
Publisher : Springer
Page : 296 pages
File Size : 48,8 Mb
Release : 2019-03-28
Category : Science
ISBN : 9783030010997

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Progress in the Chemistry of Organic Natural Products 108 by A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi,Yoshinori Asakawa,Ji-Kai Liu Pdf

The first contribution summarizes current trends in research on medicinal plants in Mexico with emphasis on work carried out at the authors' laboratories. The most relevant phytochemical and pharmacological profiles of a selected group of plants used widely for treating major national health problems are described. The second contribution provides a detailed survey of the so far reported literature data on the capacities of selected oxyprenylated phenylpropanoids and polyketides to trigger receptors, enzymes, and other types of cellular factors for which they exhibit a high degree of affinity and therefore evoke specifice responses. And the third contribution discusses aspects of endophytic actinobacterial biology and chemistry, including biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives fo the future of microbial biodiscovery, with emphasis on the seondary metabolism of endophytic actinobacteria.

Symbiotic Microbiomes of Coral Reefs Sponges and Corals

Author : Zhiyong Li
Publisher : Springer
Page : 570 pages
File Size : 40,8 Mb
Release : 2019-06-07
Category : Science
ISBN : 9789402416121

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Symbiotic Microbiomes of Coral Reefs Sponges and Corals by Zhiyong Li Pdf

This book focuses on the symbiotic microbiomes of invertebrates in coral reefs, especially sponges and corals. It provides in-depth and up-to-date reviews on the microbial structure and diversity, metabolism and function, symbiosis and coevolution, environment and adaption, and bioactive potentials. Meanwhile, the future perspectives will be discussed according to the existing problems and the development trend. This book will be of particular interest to the professionals in marine ecology, marine biotechnology, as well as medicinal chemists and molecular biologists.

Fungal Primary and Secondary Metabolism and its Importance for Virulence and Biomedical Applications

Author : Fernando Rodrigues,Laure Ries,Chengshu Wang,Koon Ho Wong
Publisher : Frontiers Media SA
Page : 164 pages
File Size : 45,6 Mb
Release : 2021-06-23
Category : Science
ISBN : 9782889668892

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Fungal Primary and Secondary Metabolism and its Importance for Virulence and Biomedical Applications by Fernando Rodrigues,Laure Ries,Chengshu Wang,Koon Ho Wong Pdf

Natural Bio-active Compounds

Author : Mohd Sayeed Akhtar,Mallappa Kumara Swamy,Uma Rani Sinniah
Publisher : Springer Nature
Page : 608 pages
File Size : 43,7 Mb
Release : 2019-09-06
Category : Science
ISBN : 9789811371547

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Natural Bio-active Compounds by Mohd Sayeed Akhtar,Mallappa Kumara Swamy,Uma Rani Sinniah Pdf

Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine. Several bioactive compounds have proved to be invaluable in mediating plant-microbe interactions, and promoting plant growth and development. Due to their numerous health-promoting properties, these compounds have been widely used as a source of medication since ancient times. However, there is an unprecedented need to meet the growing demand for natural bioactive compounds in the flavor and fragrance, food, and pharmaceutical industries. Moreover, discovering new lead molecules from natural sources is essential to overcoming the rising number of new diseases. In this regard, natural bioactive compounds hold tremendous potential for new drug discovery. Therefore, this field of research has become a vital area for researchers interested in understanding the chemistry, biosynthetic mechanisms, and pharmacological activities of these bioactive metabolites. This book describes the basics of bioactive plant compounds, their chemical properties, and their pharmacological biotechnological properties with regard to various human diseases and applications in the drug, cosmetics and herbal industries. It offers a valuable asset for all students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

Microbial Secondary Metabolites: Recent Developments and Technological Challenges

Author : Bhim Pratap Singh,Mostafa E. Rateb,Susana Rodriguez-Couto,Maria de Lourdes Teixeira de Moraes Polizeli,Wen-Jun Li
Publisher : Frontiers Media SA
Page : 309 pages
File Size : 41,9 Mb
Release : 2019-08-02
Category : Electronic
ISBN : 9782889459018

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Microbial Secondary Metabolites: Recent Developments and Technological Challenges by Bhim Pratap Singh,Mostafa E. Rateb,Susana Rodriguez-Couto,Maria de Lourdes Teixeira de Moraes Polizeli,Wen-Jun Li Pdf

Research on microbes plays an essential role in the improvement of biotechnological and biomedical areas. It has turned into a subject of expanding significance as new organisms and their related biomolecules are being characterized for several applications in health and agriculture. Microbial biomolecules confer the ability of microbes to cope with a range of adverse conditions. However, these biomolecules have several advantages over the plant origin, which makes them a suitable target in drug discovery and development. The reasons could be that microbial sources can be genetically engineered to enhance the production of desired natural production by large-scale fermentation. The interaction between microbes and their biotic and abiotic environment is fundamental to numerous processes taking place in the biosphere. The natural environments and hosts of these microorganisms are extremely diverse being reflected by the fact that microbes are widespread and occur in nearly every biological community on Earth. This metabolic versatility makes microbes interesting objects for a range of economically important biotechnological applications. Most of the biotechniques are established but inefficient genetic engineering strategies are still a bottleneck for selected microbe producing industrial scale biomolecules. Therefore, untapped microbial biodiversity and related metablomics, give a noteworthy wellspring of biologicals for the advancement of meds, immunizations, enhanced plants and for other natural applications. The present eBook volume contains articles on microbial secondary metabolites, microbial biosynthetic potential including biosynthetic gene expression, and metagenomics obtained from microorganism isolated unique from habitats like marine sources, endophytes, thermal springs, deserts, etc.

Biodiversity and Chemotaxonomy

Author : Kishan Gopal Ramawat
Publisher : Springer Nature
Page : 318 pages
File Size : 51,8 Mb
Release : 2019-11-10
Category : Science
ISBN : 9783030307462

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Biodiversity and Chemotaxonomy by Kishan Gopal Ramawat Pdf

Plant classifications are based on morphological characters and it is difficult, particularly in small plants and grasses, to identify these below generic level on the basis of these characters using a dissecting microscope. Plant species have intra- and inter-specific variation in secondary metabolites which can be utilized as marker compounds for identification and classification of plants. Secondary metabolites are produced as a result of primary metabolism and the production of these compounds not only involves several genes but also it is an energy dependent process. Hence these products cannot be considered as insignificant for the plant and the environment. Modern tools of molecular biology and secondary metabolites present in them can definitively decide about classification of plants. Absence of correct identification of plant is associated to many problems of resource utilization. Due to wide availability of these tools, interest has revived in systematics and correct classification of plants based on these parameters for their sustainable utilization and resource management. The purpose of this book is to assess the potential of phytochemical and molecular tools in the systematic and classification of plants. The topics covered include species concept, barcoding and phylogenetic analysis, chemotaxonomy use of polyketides, carotenes, cuticular wax, volatile oils, biodiversity of corals, metazoans, Ruta and Echinocereus. It provides comprehensive and broad subject-based reviews, useful for students, teachers, researchers, and all others interested in the field. The field has been kept wide and general to accommodate the wide-ranging topics. This book will be useful to agriculturists, chemists, botanists, industrialists, and those involved in planning of crop plants.

Microbial Enzymes: Roles and Applications in Industries

Author : Naveen Kumar Arora,Jitendra Mishra,Vaibhav Mishra
Publisher : Springer Nature
Page : 331 pages
File Size : 42,5 Mb
Release : 2020-04-28
Category : Science
ISBN : 9789811517105

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Microbial Enzymes: Roles and Applications in Industries by Naveen Kumar Arora,Jitendra Mishra,Vaibhav Mishra Pdf

“Microbial Enzymes: Roles and applications in industry” offers an essential update on the field of microbial biotechnology, and presents the latest information on a range of microbial enzymes such as fructosyltransferase, laccases, amylases, lipase, and cholesterol oxidase, as well as their potential applications in various industries. Production and optimisation technologies for several industrially relevant microbial enzymes are also addressed. In recent years, genetic engineering has opened up new possibilities for redesigning microbial enzymes that are useful in multiple industries, an aspect that the book explores. In addition, it demonstrates how some of the emerging issues in the fields of agriculture, environment and human health can be resolved with the aid of green technologies based on microbial enzymes. The topics covered here will not only provide a better understanding of the commercial applications of microbial enzymes, but also outline futuristic approaches to use microbial enzymes as driver of industrial sustainability. Lastly, the book is intended to provide readers with an overview of recent applications of microbial enzymes in various industrial sectors, and to pique researchers’ interest in the development of novel microbial enzyme technologies to meet the changing needs of industry.

Microbial Diversity and Biotechnology in Food Security

Author : R.N. Kharwar,R.S. Upadhyay,N.K. Dubey,Richa Raghuwanshi
Publisher : Springer
Page : 605 pages
File Size : 51,9 Mb
Release : 2014-06-11
Category : Technology & Engineering
ISBN : 9788132218012

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Microbial Diversity and Biotechnology in Food Security by R.N. Kharwar,R.S. Upadhyay,N.K. Dubey,Richa Raghuwanshi Pdf

The roles of microbes in agriculture, industry and environment have been the point of interest since long time for their potential exploitation. Although only a fraction of microbial diversity was accessed by microbiologists earlier for harnessing them owing to limited techniques available. The molecular techniques have opened new vistas to access the wide field of the unexplored microbes and their exploitation for useful genes and novel metabolites. Sincere efforts have been made in biotechnology using microbes leading to improve our life with respect to agriculture and people health. This comprehensive volume covers different aspects of microbial biotechnology and its management in sustainable agriculture for food security and improved human health. The book comprises four sections: Endophytes and Mycorrhizae, Microbial Diversity and Plant Protection, Microbial Functions and Biotechnology, and Microbes and the Environment, which contain 53 chapters. The book examines the aspects on endophytes and mycorrhizae, bioactive compounds, growth promoting microorganisms, disease management with emphasis on biocontrol, genetics of disease resistance, microbial enzymes, advances in potential of microbes and their industrial as well as pharmaceutical applications. In addition, the use of botanicals, and the etiology and management of medicinal and aromatic plants in the post harvest management have been reviewed in greater depth for the benefit of teaching and research community. The biotechnological developments using microbe potential have enabled us combat the environment and human health problems worldwide in ecofriendly manner. We are sure that this volume will be highly useful to all those concerned with fungi, bacteria, viruses and their biology, including environmental and public health officers and professionals in the field of interest. The volume is an exhaustive coverage of almost all the aspects of microbial biology and biotechnology.

Recent Advancement in White Biotechnology Through Fungi

Author : Ajar Nath Yadav,Sangram Singh,Shashank Mishra,Arti Gupta
Publisher : Springer
Page : 504 pages
File Size : 51,5 Mb
Release : 2019-04-24
Category : Science
ISBN : 9783030148461

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Recent Advancement in White Biotechnology Through Fungi by Ajar Nath Yadav,Sangram Singh,Shashank Mishra,Arti Gupta Pdf

White biotechnology is industrial biotechnology dealing with various biotech products through applications of microbes. The main application of white biotechnology is commercial production of various useful organic substances, such as acetic acid, citric acid, acetone, glycerine, etc., and antibiotics like penicillin, streptomycin, mitomycin, etc., and value added product through the use of microorganisms especially fungi and bacteria. The value-added products included bioactive compounds, secondary metabolites, pigments and industrially important enzymes for potential applications in agriculture, pharmaceuticals, medicine and allied sectors for human welfare. In the 21st century, techniques were developed to harness fungi to protect human health (through antibiotics, antimicrobial, immunosuppressive agents, value-added products etc.), which led to industrial scale production of enzymes, alkaloids, detergents, acids, biosurfactants. The first large-scale industrial applications of modern biotechnology have been made in the areas of food and animal feed production (agricultural/green biotechnology) and pharmaceuticals (medical/red biotechnology). In contrast, the production of bio-active compounds through fermentation or enzymatic conversion is known industrial or white biotechnology. The beneficial fungal strains may play important role in agriculture, industry and the medical sectors. The beneficial fungi play a significance role in plant growth promotion, and soil fertility using both, direct (solubilization of phosphorus, potassium and zinc; production of indole acetic acid, gibberellic acid, cytokinin and siderophores) and indirect (production of hydrolytic enzymes, siderophores, ammonia, hydrogen cyanides and antibiotics) mechanisms of plant growth promotion for sustainable agriculture. The fungal strains and their products (enzymes, bio-active compounds and secondary metabolites) are very useful for industry. The discovery of antibiotics is a milestone in the development of white biotechnology. Since then, white biotechnology has steadily developed and now plays a key role in several industrial sectors, providing both high valued nutraceuticals and pharmaceutical products. The fungal strains and bio-active compounds also play important role in the environmental cleaning. This volume covers the latest research developments related to value-added products in white biotechnology through fungi.

Progress in the Chemistry of Organic Natural Products 114

Author : A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi,Yoshinori Asakawa,Ji-Kai Liu
Publisher : Springer Nature
Page : 341 pages
File Size : 40,5 Mb
Release : 2021-04-01
Category : Science
ISBN : 9783030594442

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Progress in the Chemistry of Organic Natural Products 114 by A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi,Yoshinori Asakawa,Ji-Kai Liu Pdf

This book describes current understandings and recent progress in four areas: in the first one, the cytochalasans, a group of fungal derived natural products characterized by a perhydro-isoindolone core fused with a macrocyclic ring are shown to exhibit high structural diversity and a broad spectrum of bioactivities. The second one is dedicated to a description of bioactive compounds from the medicinal plants of Myanmar, the third one is dedicated to new structure elucidation techniques in the field of sesquiterpenes. The last one discusses the endogenous natural products that are produced by human cells including endogenous amines, steroids, and fatty acid derived natural products. The co-metabolism and natural product production of the human microbiome is also described including tryptophan, bile acids, choline, and cysteine.

Pharmaceutical Biotechnology

Author : Oliver Kayser,Heribert Warzecha
Publisher : John Wiley & Sons
Page : 677 pages
File Size : 51,8 Mb
Release : 2012-05-21
Category : Science
ISBN : 9783527329946

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Pharmaceutical Biotechnology by Oliver Kayser,Heribert Warzecha Pdf

This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.