The Eukaryote Genome In Development And Evolution

Author : John Bernard
Publisher : Springer Science & Business Media
Page : 432 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401159913

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The Eukaryote Genome in Development and Evolution by John Bernard Pdf

'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules in cells and tissues, the biologist now has available the most powerful reductionist tools ever invented. The application of these new technologies has led to a veritable explosion of facts regarding the types and organization of nucleotide sequences present in the genomes of eukaryotes. These data offer a level of precision and predictability which is unparalleled in biology. Recombinant DNA techniques were initially developed to gather information about the structure and organization of the DNA sequences within a genome. The power and potential of these techniques, however, extend far beyond simple data collection of this kind. In an attempt to use the new technology as a basis for analyzing development and evolution, attention was first focused on the topic of gene regulation, an approach that had proven so successful in prokaryotes. It is now clear that this has not been an adequate approach. Lewin (1984) has quoted Brenner as stating 'at the beginning it was said that the answer to the understanding of development was going to come from a knowledge of the molecular mechanisms of gene control. I doubt whether anyone believes this any more.

Author : John Bernard
Publisher : Springer
Page : 416 pages
File Size : 47,6 Mb
Release : 2012-03-08
Category : Science
ISBN : 9401159920

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The Eukaryote Genome in Development and Evolution by John Bernard Pdf

'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules in cells and tissues, the biologist now has available the most powerful reductionist tools ever invented. The application of these new technologies has led to a veritable explosion of facts regarding the types and organization of nucleotide sequences present in the genomes of eukaryotes. These data offer a level of precision and predictability which is unparalleled in biology. Recombinant DNA techniques were initially developed to gather information about the structure and organization of the DNA sequences within a genome. The power and potential of these techniques, however, extend far beyond simple data collection of this kind. In an attempt to use the new technology as a basis for analyzing development and evolution, attention was first focused on the topic of gene regulation, an approach that had proven so successful in prokaryotes. It is now clear that this has not been an adequate approach. Lewin (1984) has quoted Brenner as stating 'at the beginning it was said that the answer to the understanding of development was going to come from a knowledge of the molecular mechanisms of gene control. I doubt whether anyone believes this any more.

Author : Eric H. Davidson
Publisher : Elsevier
Page : 304 pages
File Size : 45,6 Mb
Release : 2010-07-19
Category : Science
ISBN : 0080455573

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The Regulatory Genome by Eric H. Davidson Pdf

Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams

Author : Rabindra N. Chatterjee,Lucas Sanchez
Publisher : Springer Science & Business Media
Page : 262 pages
File Size : 53,9 Mb
Release : 2013-03-09
Category : Science
ISBN : 9783662118290

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Genome Analysis in Eukaryotes by Rabindra N. Chatterjee,Lucas Sanchez Pdf

During the last decades a breakthrough in the understanding of the mechanisms controlling development has been achieved. This has been possible, in great part, by the use of various experimental approaches. This book focuses on topics concerning some of the processes involved in development, the main emphasis being on the genetic and molecular mechanisms in the evolutionary context. Drosophila is used as an experimental model for the genetic approach to the understanding of behaviour.

Author : Robert P Hirt,David S. Horner
Publisher : CRC Press
Page : 462 pages
File Size : 50,8 Mb
Release : 2004-06-28
Category : Science
ISBN : 9780203508930

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Organelles, Genomes and Eukaryote Phylogeny by Robert P Hirt,David S. Horner Pdf

The recent revolution in molecular biology has spread through every field of biology including systematics and evolution. Researchers can now analyze the genomes of different species relatively quickly, and this is generating a great deal of data and theories about relationships between taxa as well as how they originated and diversified. Org

Author : Laura A Katz,Debashish Bhattacharya
Publisher : OUP Oxford
Page : 256 pages
File Size : 45,9 Mb
Release : 2006-09-07
Category : Science
ISBN : 9780191513855

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Genomics and Evolution of Microbial Eukaryotes by Laura A Katz,Debashish Bhattacharya Pdf

Genomics and Evolution of Eukaryotic Microbes synthesizes the rapidly emerging fields of eukaryotic diversity and genome evolution. Eukaryotes (cells with nuclei) evolved as microbes and have existed on Earth for approximately two billion years. The tremendous diversity of eukaryotic microbes (protists) is often overlooked by those who study the macroscopic eukaryotic lineages: plants, animals, and fungi. Yet, eukaryotic microbes are of critical importance to ecosystems, human health, and our desire to understand biodiversity on Earth. By bringing together groundbreaking data from genome studies of diverse eukaryotic microbes, this book elucidates the many novelties among eukaryotic genomes and provides a single resource for otherwise widely dispersed information. Eukaryotic microorganisms impact both our health and our environment. These organisms include some of the deadliest known pathogens such as Plasmodium falciparum, a causative agent of malaria, and Entamoeba histolytica an agent of dysentery. Eukaryotic microbes also play a significant role in environments through their involvement in global biogeochemical cycles. Such roles are perhaps best exemplified by the coccolithophores, including the species Emiliania huxleyi, which can create 'blooms' in the oceans that are visible from outer space (i.e. as large as the state of Alaska). Despite the great importance and breadth of eukaryotic microbes (the vast majority of major ukaryotic lineages are microbial, with plants, animals and fungi representing just three of an estimated 60-200 major lineages), our understanding of their diversity and phylogeny is only now rapidly expanding, in part bolstered by genomic studies. This book presents analyses and interpretations from experts in the field. Recent advances, particularly in DNA sequencing technologies, have made eukaryotic microbes more accessible to genome analyses. Unravelling the wealth of information on eukaryotic genomes will invariably revolutionize our understanding of eukaryotes, including their physiology, systematics, and ecology.

Author : Laura Katz Olson
Publisher : Oxford University Press on Demand
Page : 256 pages
File Size : 48,8 Mb
Release : 2006-09-07
Category : Science
ISBN : 9780198569749

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Genomics and Evolution of Microbial Eukaryotes by Laura Katz Olson Pdf

This book represents a unique combination of recently-emerged information on eukaryotic microbes, evolution and genomics. Eukaryotes, cells with nuclei, evolved as microbes and have existed on Earth for approximately 2 billion years. Although currently relatively understudied, eukaryotic microorganisms are of critical importance to ecosystems (through their involvement in global biogeochemical cycles), human health (they include some of the deadliest pathogens), and our desire tounderstand global biodiversity. Recent advances, particularly in DNA sequencing technologies, are making eukaryotic microbes more accessible through genome analyses. Insights from these studies are challenging previously held theories of genome evolution, based on studies of a limited number of plants,animals and fungi.

Author : R. N. Chatterjee
Publisher : Springer Verlag
Page : 255 pages
File Size : 54,8 Mb
Release : 1998-01-01
Category : Science
ISBN : 0387635246

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Genome Analysis in Eukaryotes by R. N. Chatterjee Pdf

Author : Eric H. Davidson
Publisher : Elsevier
Page : 261 pages
File Size : 43,6 Mb
Release : 2001-01-24
Category : Science
ISBN : 0080525598

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Genomic Regulatory Systems by Eric H. Davidson Pdf

The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest. The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist. * Contents Include * Regulatory Hardwiring: A Brief Overview of the Genomic Control Apparatus and Its Causal Role in Development and Evolution * Inside the Cis-Regulatory Module: Control Logic and How the Regulatory Environment Is Transduced into Spatial Patterns of Gene Expression * Regulation of Direct Cell-Type Specification in Early Development * The Secret of the Bilaterians: Abstract Regulatory Design in Building Adult Body Parts * Changes That Make New Forms: Gene Regulatory Systems and the Evolution of Body Plans

Author : Pamela Soltis,Douglas E. Soltis
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 44,5 Mb
Release : 2012-10-03
Category : Science
ISBN : 9783642314414

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Polyploidy and Genome Evolution by Pamela Soltis,Douglas E. Soltis Pdf

Polyploidy – whole-genome duplication (WGD) – is a fundamental driver of biodiversity with significant consequences for genome structure, organization, and evolution. Once considered a speciation process common only in plants, polyploidy is now recognized to have played a major role in the structure, gene content, and evolution of most eukaryotic genomes. In fact, the diversity of eukaryotes seems closely tied to multiple WGDs. Polyploidy generates new genomic interactions – initially resulting in “genomic and transcriptomic shock” – that must be resolved in a new polyploid lineage. This process essentially acts as a “reset” button, resulting in genomic changes that may ultimately promote adaptive speciation. This book brings together for the first time the conceptual and theoretical underpinnings of polyploid genome evolution with syntheses of the patterns and processes of genome evolution in diverse polyploid groups. Because polyploidy is most common and best studied in plants, the book emphasizes plant models, but recent studies of vertebrates and fungi are providing fresh perspectives on factors that allow polyploid speciation and shape polyploid genomes. The emerging paradigm is that polyploidy – through alterations in genome structure and gene regulation – generates genetic and phenotypic novelty that manifests itself at the chromosomal, physiological, and organismal levels, with long-term ecological and evolutionary consequences.

Author : Gerhard Schlosser,Gu nter P. Wagner
Publisher : University of Chicago Press
Page : 614 pages
File Size : 47,6 Mb
Release : 2004-07
Category : Science
ISBN : 0226738531

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Modularity in Development and Evolution by Gerhard Schlosser,Gu nter P. Wagner Pdf

Modularity in Development and Evolution offers the first sustained exploration of modules from developmental and evolutionary perspectives. Contributors discuss what modularity is, how it can be identified and modeled, how it originated and evolved, and its biological significance. Covering modules at levels ranging from genes to colonies, the book focuses on their roles not just in structures but also in processes such as gene regulation. Among many exciting findings, the contributors demonstrate how modules can highlight key constraints on evolutionary processes. A timely synthesis of a crucial topic, Modularity in Development and Evolution shows the invaluable insights modules can give into both developmental complexities and their evolutionary origins.

Author : Uri Gophna
Publisher : Springer Science & Business Media
Page : 294 pages
File Size : 41,7 Mb
Release : 2013-07-20
Category : Medical
ISBN : 9781461477808

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Lateral Gene Transfer in Evolution by Uri Gophna Pdf

Although the phenomenon of lateral gene transfer has been known since the 1940's, it was the genomics era that has really revealed the extent and many facets of this evolutionary/genetic phenomenon. Even in the early 2000s with but a handful of genomes available it became clear that the nature of microorganisms is full of genetic exchange between lineages that are sometimes far apart. The years following this saw an explosion of genomic data, which shook the "tree of life" and also raised doubts about the most appropriate species concepts for prokaryotes. This book attempts to represent the many-fold contributions of LGT to the evolution of micro and, to an extent, macro-organisms by focusing on the areas where the Editor felt it had the largest impact: metabolic innovations and adaptations and speciation.

Author : Nina V. Fedoroff
Publisher : John Wiley & Sons
Page : 240 pages
File Size : 49,5 Mb
Release : 2013-04-15
Category : Science
ISBN : 9780470959947

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Plant Transposons and Genome Dynamics in Evolution by Nina V. Fedoroff Pdf

The transposable genetic elements, or transposons, as they are now known, have had a tumultuous history. Discovered in the mid-20th century by Barbara McClintock, they were initially received with puzzlement. When their genomic abundance began to be apparent, they were categorized as "junk DNA" and acquired the label of parasites. Expanding understanding of gene and genome organization has revealed the profound extent of their impact on both. Plant Transposons and Genome Dynamics in Evolution captures and distills the voluminous research literature on plant transposable elements and seeks to assemble the big picture of how transposons shape gene structure and regulation, as well as how they sculpt genomes in evolution. Individual chapters provide concise overviews of the many flavors of plant transposons and of their roles in gene creation, gene regulation, development, genome evolution, and organismal speciation, as well as of their epigenetic regulation. This volume is essential reading for anyone working in plant genetics, epigenetics, or evolutionary biology.

Author : Philip Mark Meneely,Rachel Dawes Hoang,Iruka N. Okeke,Katherine Heston
Publisher : Unknown
Page : 0 pages
File Size : 51,9 Mb
Release : 2023
Category : Genetics
ISBN : 0191975133

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Genetics by Philip Mark Meneely,Rachel Dawes Hoang,Iruka N. Okeke,Katherine Heston Pdf

This work presents the fundamental principles of genetics and molecular biology from an evolutionary perspective, as informed by genome analysis. Using what has been learned from analyses of bacterial and eukaryotic genomes as its basis, it unites evolution, genomics, and genetics in one narrative approach.

Author : Gerd B. Muller,Stuart A. Newman
Publisher : MIT Press
Page : 354 pages
File Size : 48,7 Mb
Release : 2003-01-03
Category : Science
ISBN : 0262134195

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Origination of Organismal Form by Gerd B. Muller,Stuart A. Newman Pdf

A more comprehensive version of evolutionary theory that focuses as much on the origin of biological form as on its diversification. The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of biological form. Drawing on work from developmental biology, paleontology, developmental and population genetics, cancer research, physics, and theoretical biology, this book explores the multiple factors responsible for the origination of biological form. It examines the essential problems of morphological evolution—why, for example, the basic body plans of nearly all metazoans arose within a relatively short time span, why similar morphological design motifs appear in phylogenetically independent lineages, and how new structural elements are added to the body plan of a given phylogenetic lineage. It also examines discordances between genetic and phenotypic change, the physical determinants of morphogenesis, and the role of epigenetic processes in evolution. The book discusses these and other topics within the framework of evolutionary developmental biology, a new research agenda that concerns the interaction of development and evolution in the generation of biological form. By placing epigenetic processes, rather than gene sequence and gene expression changes, at the center of morphological origination, this book points the way to a more comprehensive theory of evolution.