The Evidence Based Guide To Antidepressant Medications

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The Evidence-Based Guide to Antidepressant Medications

Author : Anthony J. Rothschild
Publisher : American Psychiatric Pub
Page : 426 pages
File Size : 42,5 Mb
Release : 2012-09-24
Category : Medical
ISBN : 9781585629800

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The Evidence-Based Guide to Antidepressant Medications by Anthony J. Rothschild Pdf

The second book in the Evidence-Based Guides series, The Evidence-Based Guide to Antidepressant Medications, provides a clear reference to the current knowledge and evidence base for the use of antidepressants among a variety of patients across a wide range of disorders. Chapters within this guide are authored by experts in their respective areas of practice, and synthesize a large amount of medical literature into a comprehensive, yet understandable, concise, reader-friendly guide. Each chapter covers both the FDA-approved and off-label use of antidepressant medications and the evidence base for their use. Each chapter also features useful tables pertaining to specific topics, such as summaries of uses and efficacy, and important clinical pearls of wisdom in the Key Clinical Concepts. Topics covered in chapters within this text include: Use of selective serotonin reuptake inhibitors, MAOIs, and tricyclic antidepressants in major depressive disorder, bipolar depression, psychotic depression, and treatment-resistant depression. Acute management of anxiety disorders, obsessive-compulsive disorder, and specific phobias through antidepressant use. Use of antidepressant medication in medically ill patients, such as those with cardiovascular, pulmonary, gastrointestinal, renal, and endocrine diseases, as well as cancer, chronic pain, HIV, burns and hospital-based trauma. Developmental considerations necessary to keep in mind when prescribing antidepressants to children and adolescents, along with an outline of controlled studies and their special attention to safety. Medication management in geriatric patients, including antidepressant use among depressed elderly patients with dementia, stroke, or Parkinson's disease. Risks and benefits of prescribing antidepressants during pregnancy and lactation. Together, the authors have synthesized a large amount of medical literature into a comprehensive, yet understandable, concise, reader-friendly guide. The Evidence-Based Guide to Antidepressant Medications is a must-have reference for psychiatrists and other practicing clinicians, residents in training, psychiatric nurses, social workers and researchers.

The Evidence-Based Guide to Antipsychotic Medications

Author : Anthony J. Rothschild
Publisher : American Psychiatric Pub
Page : 395 pages
File Size : 45,6 Mb
Release : 2010-01-12
Category : Medical
ISBN : 9781585629299

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The Evidence-Based Guide to Antipsychotic Medications by Anthony J. Rothschild Pdf

The Evidence-Based Guide to Antipsychotic Medications is designed to provide both clinicians and residents with focused, comprehensive, and clinically relevant information regarding the use of antipsychotic medications to treat a broad range of psychiatric conditions -- from mood and anxiety disorders to substance abuse, personality disorders, and schizophrenia. The volume editor is a renowned psychiatrist and author with more than 25 years of experience in both clinical and research settings diagnosing and treating patients with mood and psychotic disorders. In addition, each of the volume's 13 contributors is an expert with many years of clinical experience to draw on.The book is down-to-earth and reader-friendly and is structured for maximal utility in both coverage and format: Key Clinical Points cap each chapter, synthesizing and summarizing the knowledge you can take away, and serving both as a refresher for those using the book as a reference and as a study aid to master the material. Both FDA-approved and off-label use of antipsychotic medications are addressed, reflecting the reality of clinical practice on the front lines. Use of antipsychotic medications in both the pediatric and geriatric populations, a potentially controversial subject, is addressed in a nonsensational, straight-forward manner. The Appendixes provide a wealth of information in tabular format, including drug tables (names, strengths, formulations, pharmacokinetics, and dosing); advice on initiating and monitoring antipsychotic medications; common side effects and their management; and special considerations for use during pregnancy and breastfeeding. The Evidence-Based Guide to Antipsychotic Medications is the first in a new series that strives to take evidence-based psychiatry from gold standard to standard practice. Scientifically up-to-date and rigorous, yet accessible and easy to understand, this volume stands alone as an indispensable resource on the topic.

Evidence-biased Antidepressant Prescription

Author : Michael P. Hengartner
Publisher : Springer Nature
Page : 355 pages
File Size : 47,5 Mb
Release : 2021-12-09
Category : Psychology
ISBN : 9783030825874

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Evidence-biased Antidepressant Prescription by Michael P. Hengartner Pdf

This book addresses the over-prescribing of antidepressants in people with mostly mild and subthreshold depression. It outlines the steep increase in antidepressant prescription and critically examines the current scientific evidence on the efficacy and safety of antidepressants in depression. The book is not only concerned with the conflicting views as to whether antidepressants are useful or ineffective in various forms of depression, but also aims at detailing how flaws in the conduct and reporting of antidepressant trials have led to an overestimation of benefits and underestimation of harms. The transformation of the diagnostic concept of depression from a rare but serious disorder to an over-inclusive, highly prevalent but predominantly mild and self-limiting disorder is central to the books argument. It maintains that biological reductionism in psychiatry and pharmaceutical marketing reframed depression as a brain disorder, corroborating the overemphasis on drug treatment in both research and practice. Finally, the author goes on to explore how pharmaceutical companies have distorted the scientific literature on the efficacy and safety of antidepressants and how patient advocacy groups, leading academics, and medical organisations with pervasive financial ties to the industry helped to promote systematically biased benefit-harm evaluations, affecting public attitudes towards antidepressants as well as medical education, training, and practice.

The Antidepressant Solution

Author : Joseph Glenmullen
Publisher : Simon and Schuster
Page : 272 pages
File Size : 54,6 Mb
Release : 2006-01-20
Category : Health & Fitness
ISBN : 9780743288989

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The Antidepressant Solution by Joseph Glenmullen Pdf

With the FDA's warning that antidepressants may cause agitation, anxiety, hostility, and even violent or suicidal tendencies, these medications are at the forefront of national legal news. Harvard physician Joseph Glenmullen has led the charge to warn the public that antidepressants are overprescribed, underregulated, and, especially, misunderstood in their side and withdrawal effects. Now he offers a solution! More than twenty million Americans -- including over one million teens and children -- take one of today's popular antidepressants, such as Paxil, Zoloft, or Effexor. Dr. Glenmullen recognizes the many benefits of antidepressants and prescribes them to his patients, but he is also committed to warning the public of the dangers associated with overprescription. Dr. Glenmullen's last book, Prozac Backlash, sounded the alarm about possible dangers. The Antidepressant Solution provides the remedy. It is the first book to call attention to the drugs' catch-22: Although many people are ready to go off these drugs, they continue to take them because either the patient or the doctor mistakes antidepressant withdrawal for depressive relapse. The Antidepressant Solution offers an easy, step-by-step guide for patients and their doctors. Written by the premier authority in the field, The Antidepressant Solution is an invaluable book for all those concerned with going through the process -- from friends and family members to doctors and patients themselves.

Managing the Side Effects of Psychotropic Medications, Second Edition

Author : Joseph F. Goldberg, M.D., M.S.,Carrie L. Ernst, M.D.
Publisher : American Psychiatric Pub
Page : 618 pages
File Size : 48,7 Mb
Release : 2018-08-10
Category : Medical
ISBN : 9781585624881

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Managing the Side Effects of Psychotropic Medications, Second Edition by Joseph F. Goldberg, M.D., M.S.,Carrie L. Ernst, M.D. Pdf

This second edition of the guide features updated information about newer psychotropic agents, as well as new drugs to help manage iatrogenic weight gain, metabolic dysregulation, involuntary movement disorders, and other common problems.

American Psychiatric Association Practice Guidelines

Author : American Psychiatric Association
Publisher : American Psychiatric Publishing
Page : 368 pages
File Size : 41,5 Mb
Release : 1996
Category : Medical
ISBN : 0890423067

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American Psychiatric Association Practice Guidelines by American Psychiatric Association Pdf

The aim of the American Psychiatric Association Practice Guideline series is to improve patient care. Guidelines provide a comprehensive synthesis of all available information relevant to the clinical topic. Practice guidelines can be vehicles for educating psychiatrists, other medical and mental health professionals, and the general public about appropriate and inappropriate treatments. The series also will identify those areas in which critical information is lacking and in which research could be expected to improve clinical decisions. The Practice Guidelines are also designed to help those charged with overseeing the utilization and reimbursement of psychiatric services to develop more scientifically based and clinically sensitive criteria.

A Guide To Treatments that Work

Author : Peter Nathan,Jack M. Gorman
Publisher : Oxford University Press
Page : 705 pages
File Size : 41,9 Mb
Release : 2002-01-18
Category : Psychology
ISBN : 9780199760985

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A Guide To Treatments that Work by Peter Nathan,Jack M. Gorman Pdf

A fully revised and updated edition of this unique and authoritative reference The award-winning A Guide to Treatments that Work , published in 1998, was the first book to assemble the numerous advances in both clinical psychology and psychiatry into one accessible volume. It immediately established itself as an indispensable reference for all mental health practitioners. Now in a fully updated edition,A Guide to Treatments that Work, Second Edition brings together, once again, a distinguished group of psychiatrists and clinical psychologists to take stock of which treatments and interventions actually work, which don't, and what still remains beyond the scope of our current knowledge. The new edition has been extensively revised to take account of recent drug developments and advances in psychotherapeutic interventions. Incorporating a wealth of new information, these eminent researchers and clinicians thoroughly review all available outcome data and clinical trials and provide detailed specification of methods and procedures to ensure effective treatment for each major DSM-IV disorder. As an interdisciplinary work that integrates information from both clinical psychology and psychiatry, this new edition will continue to serve as an essential volume for practitioners of every kind: psychiatrists, psychologists, clinical social workers, counselors, and mental health consultants.

How to Practice Evidence-Based Psychiatry

Author : C. Barr Taylor
Publisher : American Psychiatric Pub
Page : 388 pages
File Size : 54,5 Mb
Release : 2009-10-30
Category : Medical
ISBN : 9781585629220

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How to Practice Evidence-Based Psychiatry by C. Barr Taylor Pdf

The use of evidence-based guidelines and algorithms is widely encouraged in modern psychiatric settings, yet many practitioners find it challenging to apply and incorporate the latest evidence-based psychosocial and biological interventions. Now, practitioners have an outstanding new resource at their fingertips. How to Practice Evidence-Based Psychiatry: Basic Principles and Case Studies accomplishes two goals: it explains the methods and philosophy of evidence-based psychiatry, and it describes ways in which psychiatrists and other mental health specialists can incorporate evidence-based psychiatry into their clinical practices. Uniquely relevant to psychiatric clinicians, this is the only book on evidence-based medicine specific to the field of psychiatry that addresses integrated psychopharmacology and psychotherapies. This new book first provides an expansion on the popular text the Concise Guide to Evidence-Based Psychiatry, updating the sections on clinical trials, the teaching of evidence-based medicine, and the effective treatment of patients with complex comorbid conditions. It then allows experts from a variety of specialty areas and practice settings to describe how they incorporate the latest evidence and outcome studies into interesting and inspiring cases of their own. The book starts with the assumption that clinicians must adapt guidelines, algorithms, other sources of evidence, and the interpretation of this evidence to each individual patient. It describes basic statistical concepts in an easily understood format and offers separate chapters devoted to systematic reviews and meta-analyses, clinical practice guidelines, diagnostic tests, surveys of disease frequency, and prognosis and psychometric measurement. It also presents an easily relatable discussion of many of the major issues of evidence-based psychiatry, such as use of the "Five-Step" evidence-based medicine model. The first section can be used both as an introduction to the topic and a ready reference for researching the literature and appraising evidence. The second section includes relevant case examples of major psychiatric disorders, and the third presents case examples from diverse treatment settings. In these sections, 24 contributing clinicians from a variety of practice settings discuss situations in which they followed aspects of evidence-based care. The text includes tables and charts throughout the text, including algorithms, guidelines, and examples of simple, therapist-devised measures of progress, further enhance learning, retention, and clinical practice. How to Practice Evidence-Based Psychiatry: Basic Principles and Case Studies is a valuable new tool that will help residents, practicing psychiatrists, and other mental health workers find the most useful and relevant information to inform and improve their everyday practices.

Prescribing Together

Author : Warren A. Kinghorn, M.D., Th.D.,Abraham M. Nussbaum, M.D., M.T.S.
Publisher : American Psychiatric Pub
Page : 298 pages
File Size : 52,7 Mb
Release : 2021-06-01
Category : Medical
ISBN : 9781615372881

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Prescribing Together by Warren A. Kinghorn, M.D., Th.D.,Abraham M. Nussbaum, M.D., M.T.S. Pdf

What if, rather than being dispensers of medication, mental health clinicians and primary care clinicians treating mental disorders were collaborators with patients in the prescribing relationship? To prescribe more effectively and to achieve health equity, Warren Kinghorn and Abraham Nussbaum argue, it's necessary--and in Prescribing Together, they offer a roadmap for making it a reality. In these pages, readers will find practical introductions to key concepts, from cultural formation and structural competency to collaborative deprescribing, and profiles, enlivened by personal anecdotes, of a diverse group of accomplished clinicians that offer evidence-based strategies for building strong alliances in the context of 13 mental disorder categories, including generalized anxiety disorder, major depressive disorder, borderline personality disorder, and neurocognitive disorders. By focusing on how, rather than what, to prescribe, this book makes room for patients' lived experiences and interpersonal and social contexts, returning to them a sense of agency and empowering them to set meaningful goals and to be active participants in their own flourishing.

Ordinarily Well

Author : Peter D. Kramer
Publisher : Macmillan + ORM
Page : 322 pages
File Size : 46,6 Mb
Release : 2016-06-07
Category : Psychology
ISBN : 9780374708962

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Ordinarily Well by Peter D. Kramer Pdf

Do antidepressants work, or are they glorified dummy pills? How can we tell? In Ordinarily Well, the celebrated psychiatrist and author Peter D. Kramer examines the growing controversy about the popular medications. A practicing doctor who trained as a psychotherapist and worked with pioneers in psychopharmacology, Kramer combines moving accounts of his patients’ dilemmas with an eye-opening history of drug research to cast antidepressants in a new light. Kramer homes in on the moment of clinical decision making: Prescribe or not? What evidence should doctors bring to bear? Using the wide range of reference that readers have come to expect in his books, he traces and critiques the growth of skepticism toward antidepressants. He examines industry-sponsored research, highlighting its shortcomings. He unpacks the “inside baseball” of psychiatry—statistics—and shows how findings can be skewed toward desired conclusions. Kramer never loses sight of patients. He writes with empathy about his clinical encounters over decades as he weighed treatments, analyzed trial results, and observed medications’ influence on his patients’ symptoms, behavior, careers, families, and quality of life. He updates his prior writing about the nature of depression as a destructive illness and the effect of antidepressants on traits like low self-worth. Crucially, he shows how antidepressants act in practice: less often as miracle cures than as useful, and welcome, tools for helping troubled people achieve an underrated goal—becoming ordinarily well.

Psychiatric Drug Withdrawal

Author : Peter Roger Breggin,Peter R. Breggin, MD
Publisher : Springer Publishing Company
Page : 335 pages
File Size : 41,7 Mb
Release : 2012-07-19
Category : Medical
ISBN : 9780826108432

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Psychiatric Drug Withdrawal by Peter Roger Breggin,Peter R. Breggin, MD Pdf

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Rang & Dale's Pharmacology

Author : James M. Ritter,Rod J. Flower,Graeme Henderson,Yoon Kong Loke,David MacEwan,Humphrey P. Rang
Publisher : Elsevier Health Sciences
Page : 808 pages
File Size : 45,8 Mb
Release : 2018-11-04
Category : Medical
ISBN : 9780702074462

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Rang & Dale's Pharmacology by James M. Ritter,Rod J. Flower,Graeme Henderson,Yoon Kong Loke,David MacEwan,Humphrey P. Rang Pdf

World-renowned coverage of today’s pharmacology at your fingertips Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more. Includes access to unique features, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment. Features a color-coded layout for faster navigation and cross-referencing. Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout.

Rational Psychopharmacology

Author : H. Paul Putman III, M.D., DLFAPA
Publisher : American Psychiatric Pub
Page : 336 pages
File Size : 47,7 Mb
Release : 2020-06-04
Category : Medical
ISBN : 9781615373130

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Rational Psychopharmacology by H. Paul Putman III, M.D., DLFAPA Pdf

"Most books about psychopharmacology focus heavily on the basic science involved and describe the currently available medications, including brief rationales for their use as well as their dosages and their side effects. Others are more for the general public, intended to help them understand how psychopharmacology might be helpful. This book is different. The goal is to teach the reader what medicines are available and what their characteristics are as well as teach very valuable skills: how to think thoroughly and methodically when assessing a patient, when reviewing research data (both basic and clinical), and when thinking through, developing, and monitoring the most effective clinical recommendations for patients. Rather than a lesson in elementary patient assessment, this book is an attempt to help readers identify weaknesses in their practice style and improve them where psychopharmacology is involved"--

Electroconvulsive Therapy in Children and Adolescents

Author : Neera Ghaziuddin,Garry Walter
Publisher : Oxford University Press
Page : 311 pages
File Size : 46,5 Mb
Release : 2013-12
Category : Medical
ISBN : 9780199937899

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Electroconvulsive Therapy in Children and Adolescents by Neera Ghaziuddin,Garry Walter Pdf

This is a pioneering book about the use of ECT in adolescents who are diagnosed with severe, disabling psychiatric disorders or fail conventional treatment. Included are a review of the literature, firsthand experience of the authors and case descriptions making it an invaluable guide to treatment.

Fluoxetine

Author : Graziano Pinna
Publisher : Unknown
Page : 412 pages
File Size : 54,9 Mb
Release : 2015-04-01
Category : Electronic
ISBN : 1634820762

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Fluoxetine by Graziano Pinna Pdf

Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure.