The Genome Incorporated

The Genome Incorporated Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of The Genome Incorporated book. This book definitely worth reading, it is an incredibly well-written.

The Genome Incorporated

Kate O'Riordan
The Genome Incorporated Book PDF

Author : Kate O'Riordan
Publisher : Routledge
Page : 164 pages
File Size : 41,9 Mb
Release : 2016-03-09
Category : Social Science
ISBN : 9781317030706

Get Book

The Genome Incorporated by Kate O'Riordan Pdf

The Genome Incorporated examines the proliferation of human genomics across contemporary media cultures. It explores questions about what it means for a technoscience to thoroughly saturate everyday life, and places the interrogation of the science/media relationship at the heart of this enquiry. The book develops a number of case studies in the mediation and consumption of genomics, including: the emergence of new direct-to-the-consumer bioinformatics companies; the mundane propagation of testing and genetic information through lifestyle television programming; and public and private engagements with art and science institutions and events. Through these novel sites, this book examines the proliferating circuits of production and consumption of genetic information and theorizes this as a process of incorporation. Its wide-ranging case studies ensure its appeal to readers across the social sciences.

The Genome Incorporated

Kate O'Riordan
The Genome Incorporated Book PDF

Author : Kate O'Riordan
Publisher : Routledge
Page : 179 pages
File Size : 53,5 Mb
Release : 2016-03-09
Category : Social Science
ISBN : 9781317030690

Get Book

The Genome Incorporated by Kate O'Riordan Pdf

The Genome Incorporated examines the proliferation of human genomics across contemporary media cultures. It explores questions about what it means for a technoscience to thoroughly saturate everyday life, and places the interrogation of the science/media relationship at the heart of this enquiry. The book develops a number of case studies in the mediation and consumption of genomics, including: the emergence of new direct-to-the-consumer bioinformatics companies; the mundane propagation of testing and genetic information through lifestyle television programming; and public and private engagements with art and science institutions and events. Through these novel sites, this book examines the proliferating circuits of production and consumption of genetic information and theorizes this as a process of incorporation. Its wide-ranging case studies ensure its appeal to readers across the social sciences.

Human Herpesviruses

Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi
Human Herpesviruses Book PDF

Author : Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi
Publisher : Cambridge University Press
Page : 1325 pages
File Size : 49,5 Mb
Release : 2007-08-16
Category : Medical
ISBN : 9781139461641

Get Book

Human Herpesviruses by Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi Pdf

This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Genomics in the Cloud

Geraldine A. Van der Auwera,Brian D. O'Connor
Genomics in the Cloud Book PDF

Author : Geraldine A. Van der Auwera,Brian D. O'Connor
Publisher : O'Reilly Media
Page : 496 pages
File Size : 47,5 Mb
Release : 2020-04-02
Category : Computers
ISBN : 9781491975169

Get Book

Genomics in the Cloud by Geraldine A. Van der Auwera,Brian D. O'Connor Pdf

Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytes—or over 50 million gigabytes—of genomic data, and they’re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud? With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian O’Connor of the UC Santa Cruz Genomics Institute, guide you through the process. You’ll learn by working with real data and genomics algorithms from the field. This book covers: Essential genomics and computing technology background Basic cloud computing operations Getting started with GATK, plus three major GATK Best Practices pipelines Automating analysis with scripted workflows using WDL and Cromwell Scaling up workflow execution in the cloud, including parallelization and cost optimization Interactive analysis in the cloud using Jupyter notebooks Secure collaboration and computational reproducibility using Terra

Retroviruses

John M. Coffin,Stephen H. Hughes,Harold Varmus
Retroviruses Book PDF

Author : John M. Coffin,Stephen H. Hughes,Harold Varmus
Publisher : CSHL Press
Page : 856 pages
File Size : 49,9 Mb
Release : 1997
Category : Electronic books
ISBN : 0879695714

Get Book

Retroviruses by John M. Coffin,Stephen H. Hughes,Harold Varmus Pdf

For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.

Origin and Evolution of Viruses

Esteban Domingo,Colin R. Parrish,John J. Holland
Origin and Evolution of Viruses Book PDF

Author : Esteban Domingo,Colin R. Parrish,John J. Holland
Publisher : Elsevier
Page : 573 pages
File Size : 46,7 Mb
Release : 2008-06-23
Category : Science
ISBN : 9780080564968

Get Book

Origin and Evolution of Viruses by Esteban Domingo,Colin R. Parrish,John J. Holland Pdf

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

Holland-Frei Cancer Medicine

Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Holland Frei Cancer Medicine Book PDF

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 45,6 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

Get Book

Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Human Genome Editing

National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
Human Genome Editing Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
Publisher : National Academies Press
Page : 329 pages
File Size : 54,7 Mb
Release : 2017-08-13
Category : Medical
ISBN : 9780309452885

Get Book

Human Genome Editing by National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations Pdf

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Evolution by Gene Duplication

Susumu Ohno
Evolution by Gene Duplication Book PDF

Author : Susumu Ohno
Publisher : Springer Science & Business Media
Page : 171 pages
File Size : 48,5 Mb
Release : 2013-12-11
Category : Medical
ISBN : 9783642866593

Get Book

Evolution by Gene Duplication by Susumu Ohno Pdf

It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.

Genomes and What to Make of Them

Barry Barnes,John Dupré
Genomes and What to Make of Them Book PDF

Author : Barry Barnes,John Dupré
Publisher : University of Chicago Press
Page : 282 pages
File Size : 50,9 Mb
Release : 2009-05-15
Category : Science
ISBN : 9780226172965

Get Book

Genomes and What to Make of Them by Barry Barnes,John Dupré Pdf

The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits—and warnings of the dangers—of genomics have remained front-page news, with everyone agreeing that genomics has the potential to radically alter life as we know it. For the nonscientist, the claims and counterclaims are dizzying—what does it really mean to understand the genome? Barry Barnes and John Dupré offer an answer to that question and much more in Genomes and What to Make of Them, a clear and lively account of the genomic revolution and its promise. The book opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter; from there the authors delve into the use of genomics in determining evolutionary paths—and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupré then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics, and the stark choices that face us—between biological warfare and gene therapy, a new eugenics or a new agricultural revolution—will demand the full engagement of both scientists and citizens. Written in straightforward language but without denying the complexity of the issues, Genomes and What to Make of Them is both an up-to-date primer and a blueprint for the future.

The Origins of Genome Architecture

Michael Lynch
The Origins of Genome Architecture Book PDF

Author : Michael Lynch
Publisher : Sinauer
Page : 518 pages
File Size : 51,9 Mb
Release : 2007-06
Category : Medical
ISBN : UOM:49015003406510

Get Book

The Origins of Genome Architecture by Michael Lynch Pdf

The availability of genomic blueprints for hundreds of species has led to a transformation in biology, encouraging the proliferation of adaptive arguments for the evolution of genomic features. This text explains why the details matter and presents a framework for how the architectural diversity of eukaryotic genomes and genes came to arise.

Genomic Selection in Animals

Joel Weller
Genomic Selection in Animals Book PDF

Author : Joel Weller
Publisher : John Wiley & Sons
Page : 189 pages
File Size : 48,6 Mb
Release : 2016-03-07
Category : Science
ISBN : 9780470960073

Get Book

Genomic Selection in Animals by Joel Weller Pdf

The field of whole genome selection has quickly developed into the breeding methodology of the future. As efforts to map a wide variety of animal genomes have matured and full animal genomes are now available for many animal scientists and breeders are looking to apply these techniques to livestock production. Providing a comprehensive, forward-looking review of animal genomics, Genomic Selection in Animals provides coverage of genomic selection in a variety of economically important species including cattle, swine, and poultry. The historical foundations of genomic selection are followed by chapters that review and assess current techniques. The final chapter looks toward the future and what lies ahead for field as application of genomic selection becomes more widespread. A concise, useful summary of the field by one of the world’s leading researchers, Genomic Selection in Animals fills an important gap in the literature of animal breeding and genomics.

Human Retroviruses

Bryan Cullen
Human Retroviruses Book PDF

Author : Bryan Cullen
Publisher : Oxford University Press
Page : 220 pages
File Size : 41,5 Mb
Release : 1993
Category : Gene Expression Regulation.
ISBN : 0199633827

Get Book

Human Retroviruses by Bryan Cullen Pdf

The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.

Retroviral Proteases

Lawrence C. Kuo,Jules A. Shafer
Retroviral Proteases Book PDF

Author : Lawrence C. Kuo,Jules A. Shafer
Publisher : Gulf Professional Publishing
Page : 494 pages
File Size : 44,8 Mb
Release : 1994-09-22
Category : Medical
ISBN : 0121821420

Get Book

Retroviral Proteases by Lawrence C. Kuo,Jules A. Shafer Pdf

Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.

Genomics and Personalized Medicine

Michael Snyder
Genomics and Personalized Medicine Book PDF

Author : Michael Snyder
Publisher : Oxford University Press
Page : 240 pages
File Size : 49,9 Mb
Release : 2016-02-09
Category : Science
ISBN : 9780190234782

Get Book

Genomics and Personalized Medicine by Michael Snyder Pdf

In 2001 the Human Genome Project succeeded in mapping the DNA of humans. This landmark accomplishment launched the field of genomics, the integrated study of all the genes in the human body and the related biomedical interventions that can be tailored to benefit a person's health. Today genomics, part of a larger movement toward personalized medicine, is poised to revolutionize health care. By cross-referencing an individual's genetic sequence -- their genome -- against known elements of "Big Data," elements of genomics are already being incorporated on a widespread basis, including prenatal disease screening and targeted cancer treatments. With more innovations soon to arrive at the bedside, the promise of the genomics revolution is limitless. This entry in the What Everyone Needs to Know series offers an authoritative resource on the prospects and realities of genomics and personalized medicine. As this science continues to alter traditional medical paradigms, consumers are faced with additional options and more complicated decisions regarding their health care. This book provides the essential information everyone needs.