The Ion Channel Factsbook Extracellular Ligand Gated Channels

Author : Anonim
Publisher : Academic Press
Page : 471 pages
File Size : 42,7 Mb
Release : 1995-11-16
Category : Science
ISBN : 9780080535197

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Ion Channel Factsbook by Anonim Pdf

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, sequence information, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for.In a set of four inter-related volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signalling phenomena in living cells. The first volume is devoted to Extracellular Ligand-Gated Integral Receptor-Channel Families including those molecular complexes activated by: 5-Hydroxytryptamine, ATP, Glutamate, Acetylcholine, GABA, Glycine. Nomenclature Expression Sequence analyses Structure and function Electrophysiology Pharmacology Information retrieval

Author : Edward C. Conley
Publisher : Unknown
Page : 128 pages
File Size : 55,6 Mb
Release : 1996
Category : Ion channels
ISBN : LCCN:98086472

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The Ion Channel Factsbook: Extracellular ligand-gated channels by Edward C. Conley Pdf

This volume covers extracellular ligand-gated ion channels. It catalogues current research on this group of molecules, central to the phenomenon of cell signallling. Entries cover four main groups of characterized ion channels, including: ELG CAT 5-HT3; ELT CAT GLU NMDA; and ELG CI GABa.

Author : Edward C. Conley,William J. Brammar
Publisher : Academic Press
Page : 908 pages
File Size : 50,8 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015043770679

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Ion Channel Factsbook by Edward C. Conley,William J. Brammar Pdf

This volume covers extracellular ligand-gated ion channels. It catalogues current research on this group of molecules, central to the phenomenon of cell signallling. Entries cover four main groups of characterized ion channels, including: ELG CAT 5-HT3; ELT CAT GLU NMDA; and ELG CI GABa.

Author : Anonim
Publisher : Academic Press
Page : 426 pages
File Size : 40,8 Mb
Release : 1995-12-14
Category : Science
ISBN : 0121844501

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Ion Channel Factsbook by Anonim Pdf

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, sequence information, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for. In a set of four inter-related volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signalling phenomena in living cells. The first volume is devoted to Extracellular Ligand-Gated Integral Receptor-Channel Families including those molecular complexes activated by: 5-Hydroxytryptamine, ATP, Glutamate, Acetylcholine, GABA, Glycine. Nomenclature Expression Sequence analyses Structure and function Electrophysiology Pharmacology Information retrieval

Author : William J. Brammar
Publisher : Academic Press
Page : 905 pages
File Size : 53,5 Mb
Release : 1998-10-16
Category : Science
ISBN : 9780080535203

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Ion Channel Factsbook by William J. Brammar Pdf

The Academic Press FactsBooks series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'a growing series of excellent manuals' by Molecular Medicine Today, and 'essential works of reference' by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. As they are meticulously researched and use an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity.In a set of four interrelated volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signaling phenomena in living cells. The fourth volume is devoted to Voltage-gated Channel Families, including those molecular complexes activated or modulated by calcium, potassium, and chloride. Nomenclature Expression Sequence Analyses Structure and function Electrophysiology Pharmacology Information retrieval

Author : Edward Conley,William J. Brammar
Publisher : Academic Press
Page : 836 pages
File Size : 41,9 Mb
Release : 1996
Category : Medical
ISBN : WISC:89057638645

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Ion Channel Factsbook by Edward Conley,William J. Brammar Pdf

This volume covers extracellular ligand-gated ion channels. It catalogues current research on this group of molecules, central to the phenomenon of cell signallling. Entries cover four main groups of characterized ion channels, including: ELG CAT 5-HT3; ELT CAT GLU NMDA; and ELG CI GABa.

Author : Edward C. Conley
Publisher : Unknown
Page : 860 pages
File Size : 48,9 Mb
Release : 1999
Category : Biology
ISBN : OCLC:505081841

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The Ion Channel Factsbook by Edward C. Conley Pdf

Author : James N. C. Kew,Ceri H. Davies
Publisher : Unknown
Page : 586 pages
File Size : 49,9 Mb
Release : 2010
Category : Medical
ISBN : 9780199296750

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Ion Channels by James N. C. Kew,Ceri H. Davies Pdf

Ion channels are intimately involved in the everyday physiological functions that enable us to live a full and varied life. When disease strikes, malfunction of ion channels or their dependent is often involved, either as the cause or the effect of the illness. Thus, billions of dollars have been, and still are being, invested in research to understand the physiological and pathophysiological functions of ion channels in an attempt to develop novel therapeutic treatments for a wide range of diseases. This book provides a comprehensive overview of ion channel structure and function. It comprises two major parts. Part one is an introductory overview of the ion channel superfamily and the generic aspects of ion channel function. This part also reviews the methodologies by which ion channel function can be studied from the perspective of performing detailed biophysical characterization through to the deployment of high throughput approaches for identifying novel ion channel ligands. Part two of the book provides an in-depth review of the individual ion channel subfamilies and, as such, is subdivided into four broad sections: Voltage-Gated Ion Channels, Extracellular Ligand-Gated Ion Channels, Intracellular Ligand-Gated Ion Channels, and Polymodal-Gated Ion Channels, with each chapter focused on specific family members. These chapters have been written by world leading experts and provide a detailed overview of the structure, biophysics, localization, pharmacology, physiology, and disease relevance of each particular ion channel subfamily. Reviewing both the basic principles of ion channel function and providing a detailed up-to-date review of the phsyiological and pharmacological aspects of individual ion channel sub-families, this book constitutes both an excellent introduction to the field for non-specialists, as well as a highly valuable reference text for experienced researchers already working in the ion channel area.

Author : Jie Zheng,Matthew C. Trudeau
Publisher : CRC Press
Page : 331 pages
File Size : 54,9 Mb
Release : 2023-06-09
Category : Medical
ISBN : 9781000857757

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Textbook of Ion Channels Volume I by Jie Zheng,Matthew C. Trudeau Pdf

The Textbook of Ion Channels is a set of three volumes providing a wide-ranging reference source on ion channels for students, instructors and researchers. Ion channels are membrane proteins that control the electrical properties of neurons and cardiac cells; mediate the detection and response to sensory stimuli like light, sound, odor, and taste; and regulate the response to physical stimuli like temperature and pressure. In non-excitable tissues, ion channels are instrumental for the regulation of basic salt balance that is critical for homeostasis. Ion channels are located at the surface membrane of cells, giving them the unique ability to communicate with the environment, as well as the membrane of intracellular organelles, allowing them to regulate internal homeostasis. Ion channels are fundamentally important for human health and diseases, and are important targets for pharmaceuticals in mental illness, heart disease, anesthesia, pain and other clinical applications. The modern methods used in their study are powerful and diverse, ranging from single ion-channel measurement techniques to models of ion channel diseases in animals, and human clinical trials for ion channel drugs. Volume I, Part 1 covers fundamental topics such as the basic principles of ion permeation and selectivity, voltage-dependent, ligand-dependent, and mechano-dependent ion channel activation mechanisms, the mechanisms for ion channel desensitization and inactivation, and basic ion channel pharmacology and inhibition. Volume I, Part 2 offers a practical guide of cardinal methods for researching ion channels, including heterologous expression and voltage-clamp and patch-clamp electrophysiology; isolation of native currents using patch clamping; modeling ion channel gating, structures, and its dynamics; crystallography and cryo-electron microscopy; fluorescence and paramagnetic resonance spectroscopy methods; and genetics approaches in model organisms. All three volumes give the reader an introduction to fundamental concepts needed to understand the mechanism of ion channels; a guide to the technical aspects of ion channel research; a modern guide to the properties of major ion channel families; and includes coverage of key examples of regulatory, physiological and disease roles for ion channels.

Author : Edward C. Conley
Publisher : Academic Press
Page : 778 pages
File Size : 41,5 Mb
Release : 2001-09
Category : Biological transport
ISBN : 0121844498

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The Ion Channel FactsBook by Edward C. Conley Pdf

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 50,5 Mb
Release : 2024-07-01
Category : Electronic
ISBN : OCLC:1403467883

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The Ion Channel Factsbook by Anonim Pdf

Author : Shirley Ayad,Ray Boot-Handford,Martin Humphries,Karl Kadler,Adrian Shuttleworth
Publisher : Elsevier
Page : 314 pages
File Size : 48,5 Mb
Release : 1998-03-27
Category : Science
ISBN : 9780080531519

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The Extracellular Matrix Factsbook by Shirley Ayad,Ray Boot-Handford,Martin Humphries,Karl Kadler,Adrian Shuttleworth Pdf

The Second Edition of The Extracellular Matrix FactsBook has been completely revised, updated and expanded by over 50 percent. It contains over 85 entries on the diverse group of macromolecules that assemble toform the extracellular matrix. Entries provide information on molecular structure, isolation, primary structure, structural and functional sites, gene structure, database accession numbers, and key references. Key Features * Compiled by members of one of the foremost centers of matrix biochemistry in the world * Contains over 30 new entries, with all previous entries being revised and updated * Includes new entries on proteinases involved in the deposition of the extracellular matrix * Presents 3D ribbon diagrams in cases where the protein structure is now known

Author : Marie-Paule Lefranc,Gerard Lefranc
Publisher : Gulf Professional Publishing
Page : 472 pages
File Size : 44,9 Mb
Release : 2001-05-29
Category : Medical
ISBN : 9780124413511

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The Immunoglobulin FactsBook by Marie-Paule Lefranc,Gerard Lefranc Pdf

The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field. The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.

Author : Vincent Laudet,Hinrich Gronemeyer
Publisher : Gulf Professional Publishing
Page : 486 pages
File Size : 43,9 Mb
Release : 2002
Category : Medical
ISBN : 0124377351

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The Nuclear Receptor FactsBook by Vincent Laudet,Hinrich Gronemeyer Pdf

The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure, Isolation, DNA binding properties, Ligands, Expression, Target genes, Knockouts, Disease association, Gene structure, promoter and isoforms, Chromosomal location, Amino acid sequences, Key references

Author : Scott R. Barnum
Publisher : Academic Press
Page : 237 pages
File Size : 50,9 Mb
Release : 1999-10-28
Category : Medical
ISBN : 9780080529554

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The Complement FactsBook by Scott R. Barnum Pdf

The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies. Includes the cDNA sequences, marked with intron/exon boundaries, facilitating genetic studies Presents detailed structural information including cDNA and gene structure for all proteins Introduces complement function, simply described for each function Data is as up-to-date as possible, including unpublished work from many contributors Incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, familiesEach chapter has been written by an expert in the field Data is as up-to-date as possible, including unpublished work from many contributors Entries provide information on: Alternative nomenclature, Physiochemical properties, Structure and function, Tissue distribution and regulation expression, Protein sequence/modules, Chromosomal location, Genomic structure, Database accession numbers, Deficiency and polymorphic variants, Key references