The Neurological Emergence Of Epilepsy

Author : Vasia Lekka
Publisher : Springer
Page : 209 pages
File Size : 46,5 Mb
Release : 2014-06-19
Category : Science
ISBN : 9783319062938

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The Neurological Emergence of Epilepsy by Vasia Lekka Pdf

This book explores the emergence of epilepsy as a purely neurological disorder, in the second half of the nineteenth century. It focuses on the world’s first neurological hospital, the National Hospital for the Paralysed and Epileptic in London, and on its leading figure, John Hughlings Jackson (1835-1911). Through an analysis of the National Hospital’s medical records and a historical account of the course of epilepsy until our time, this book presents the nineteenth-century turn towards the scientific study of the human brain and the various political, social, ideological and epistemological implications of this major change. In spite of the recent trend of describing the history of mental illness, mental patients and psychiatric institutions, so far, neurology, epilepsy and epileptic patients have largely remained outside the scope of social historians, historians of medicine and social scientists. This book has the ambition to fill that gap.

Author : Walter J. Friedlander
Publisher : Bloomsbury Publishing USA
Page : 310 pages
File Size : 40,6 Mb
Release : 2001-05-30
Category : Health & Fitness
ISBN : 9780313003110

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The History of Modern Epilepsy by Walter J. Friedlander Pdf

Although the history of epilepsy, one of the most common serious neurological disorders, can easily be traced back to ancient times, the modern understanding of the disease only began in the middle of the 19th century. This history of the first fifty years of modern epileptology reflects the thinking, accomplishments, and failures of physicians between 1865 and 1914. This epoch presented a very bleak clinical picture: diagnosis was difficult and often arbitrary; treatment was poor and, at times, worse than the disease; and patients, who were usually viewed as having a progressive dementing condition, were shunned by society. Tradition, physicians' immaculate perceptions, their thinking in analogies, and the difficulty a doctor has in separating himself from his society are some of the important factors which led to a lack of clinical advancement during this time. Nevertheless, taking a longer view, a foundation was being established for understanding the physiology of the brain and how that might be related to epilepsy. This book should be of interest to any professional person concerned with or involved in exploring the neurophysiology of brain functions and its deviations, the care and treatment of patience with epilepsy, and the historical and social aspects of medicine.

Author : J. Kiffin Penry
Publisher : Unknown
Page : 128 pages
File Size : 53,8 Mb
Release : 1978
Category : Epilepsy
ISBN : LCCN:79601844

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Indexes to the Epilepsy Accessions of the Epilepsy Information System by J. Kiffin Penry Pdf

Author : Simon Shorvon,Renzo Guerrini,Eugen Trinka,Steven Schachter
Publisher : Cambridge University Press
Page : 1013 pages
File Size : 50,7 Mb
Release : 2019-05-02
Category : Medical
ISBN : 9781108420754

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The Causes of Epilepsy by Simon Shorvon,Renzo Guerrini,Eugen Trinka,Steven Schachter Pdf

Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

Author : Mervyn J. Eadie,Peter F. Bladin
Publisher : John Libbey Eurotext
Page : 260 pages
File Size : 45,9 Mb
Release : 2001
Category : Medical
ISBN : UOM:39015054375103

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A Disease Once Sacred by Mervyn J. Eadie,Peter F. Bladin Pdf

Uses current knowledge of epilepsy and epileptic seizures as a yardstick against which to interpret the thinking of the past. Attempts to trace the development of thought about individual aspects of the understanding of epilepsy one after the other and on a chronological basis.

Author : Jerome Engel Jr
Publisher : Oxford University Press
Page : 737 pages
File Size : 48,7 Mb
Release : 2013-01-31
Category : Medical
ISBN : 9780195328547

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Seizures and Epilepsy by Jerome Engel Jr Pdf

This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Author : Gonzalo Alarcón,Antonio Valentín
Publisher : Cambridge University Press
Page : 641 pages
File Size : 41,5 Mb
Release : 2012-04-26
Category : Medical
ISBN : 9780521691581

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Introduction to Epilepsy by Gonzalo Alarcón,Antonio Valentín Pdf

Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.

Author : Jong Rho,Raman Sankar,Carl E. Stafstrom
Publisher : CRC Press
Page : 684 pages
File Size : 54,9 Mb
Release : 2010-06-18
Category : Medical
ISBN : 9781420085600

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Epilepsy by Jong Rho,Raman Sankar,Carl E. Stafstrom Pdf

Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervo

Author : Simon Shorvon
Publisher : Cambridge University Press
Page : 761 pages
File Size : 53,5 Mb
Release : 2023-02-02
Category : Medical
ISBN : 9781108842617

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The Idea of Epilepsy by Simon Shorvon Pdf

The definitive and scholarly history of the modern era of epilepsy, covering its medical, scientific, societal and personal aspects.

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 52,5 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : Chrysostomos P. Panayiotopoulos
Publisher : Springer
Page : 570 pages
File Size : 47,5 Mb
Release : 2005
Category : Medical
ISBN : UOM:39015062497741

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The Epilepsies by Chrysostomos P. Panayiotopoulos Pdf

This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

Author : Jeffrey L. Noebels,Massimo Avoli
Publisher : OUP USA
Page : 1258 pages
File Size : 50,5 Mb
Release : 2012-06-29
Category : Medical
ISBN : 9780199746545

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Jasper's Basic Mechanisms of the Epilepsies by Jeffrey L. Noebels,Massimo Avoli Pdf

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author : Isam Jaber Al-Zwaini,Ban Adbul-Hameed Majeed Albadri
Publisher : BoD – Books on Demand
Page : 221 pages
File Size : 41,5 Mb
Release : 2019-11-13
Category : Medical
ISBN : 9781789238679

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Epilepsy by Isam Jaber Al-Zwaini,Ban Adbul-Hameed Majeed Albadri Pdf

Epilepsy is the most common neurological disorder globally, affecting approximately 50 million people of all ages. It is one of the oldest diseases described in literature from remote ancient civilizations 2000-3000 years ago. Despite its long history and wide spread, epilepsy is still surrounded by myth and prejudice, which can only be overcome with great difficulty. The term epilepsy is derived from the Greek verb epilambanein, which by itself means to be seized and to be overwhelmed by surprise or attack. Therefore, epilepsy is a condition of getting over, seized, or attacked. The twelve very interesting chapters of this book cover various aspects of epileptology from the history and milestones of epilepsy as a disease entity, to the most recent advances in understanding and diagnosing epilepsy.

Author : Jacqueline A. Hubbard,Devin K. Binder
Publisher : Academic Press
Page : 394 pages
File Size : 43,7 Mb
Release : 2016-07-05
Category : Medical
ISBN : 9780128026243

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Astrocytes and Epilepsy by Jacqueline A. Hubbard,Devin K. Binder Pdf

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation

Author : S.D. Shorvon
Publisher : Butterworth-Heinemann
Page : 120 pages
File Size : 44,5 Mb
Release : 2013-10-22
Category : Health & Fitness
ISBN : 9781483182681

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Neurological Emergencies by S.D. Shorvon Pdf

Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.