The Neuroscience Of Depression

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The Neuroscience of Depression

Colin R Martin,Lan-Anh Hunter,Vinood B. Patel,Victor R Preedy,Rajkumar Rajendram
The Neuroscience of Depression Book PDF

Author : Colin R Martin,Lan-Anh Hunter,Vinood B. Patel,Victor R Preedy,Rajkumar Rajendram
Publisher : Academic Press
Page : 594 pages
File Size : 47,5 Mb
Release : 2021-03-05
Category : Psychology
ISBN : 9780128179345

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The Neuroscience of Depression by Colin R Martin,Lan-Anh Hunter,Vinood B. Patel,Victor R Preedy,Rajkumar Rajendram Pdf

The Neuroscience of Depression: Features, Diagnosis and Treatment, is a comprehensive reference to the diagnosis and treatment of depression. This book provides readers with the mechanisms of depression reflecting on the interplay between depression and the biological and psychosocial processes. A detailed introduction to various episodes of depression, from PTSD to post-partum depression is provided, followed by a thorough discussion on biomarkers in depression and how to diagnose depression including the Hamilton Depression Rating scale. This book also includes three full sections on treatment options for depression, including pharmacological, behavioral and other novel regimes. The Neuroscience of Depression: Features, Diagnosis and Treatment is the only resource for researchers and practitioners studying, diagnosis and treating of depression. Covers a pharmacological and behavioral treatment options Features sections on diagnosis and biomarkers of depression Discusses depression in children, teens and adults Contains information on comorbidity of physical and mental conditions Includes more than 250 illustrations and tables

Systems Neuroscience in Depression

Thomas Frodl
Systems Neuroscience in Depression Book PDF

Author : Thomas Frodl
Publisher : Academic Press
Page : 420 pages
File Size : 40,9 Mb
Release : 2016-09-01
Category : Psychology
ISBN : 9780128026281

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Systems Neuroscience in Depression by Thomas Frodl Pdf

Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. Knowledge covering the whole life span from early to later life Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience Understanding the neurobiology of major depressive disorder Integrating stress and environmental factors with molecular underpinnings More than 25 illustrations and tables

The Neuroscience of Depression

Colin R Martin,Lan-Anh Hunter,Vinood Patel,Victor R Preedy,Rajkumar Rajendram
The Neuroscience of Depression Book PDF

Author : Colin R Martin,Lan-Anh Hunter,Vinood Patel,Victor R Preedy,Rajkumar Rajendram
Publisher : Academic Press
Page : 1170 pages
File Size : 48,7 Mb
Release : 2021-04-30
Category : Medical
ISBN : 9780128180105

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The Neuroscience of Depression by Colin R Martin,Lan-Anh Hunter,Vinood Patel,Victor R Preedy,Rajkumar Rajendram Pdf

The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is a comprehensive reference to the aspects, features and effects of depression. This book provides readers with the behavior and psychopathological effects of depression, linking anxiety, anger and PSTD to depression. Readers are provided with a detailed outline of the genetic aspects of depression including synaptic genes and the genome-wide association studies (GWAS) of depression, followed by a thorough analysis of the neurological and imaging techniques used to study depression. This book also includes three full sections on the various effects of depression, including diet, nutrition and molecular and cellular effects. The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is the only resource for researchers and practitioners studying depression. The Neuroscience of Depression: Features, Diagnosis and Treatment Covers a pharmacological and behavioral treatment options Features sections on diagnosis and biomarkers of depression Discusses depression in children, teens and adults Contains information on comorbidity of physical and mental conditions Includes more than 250 illustrations and tables The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet Features a section on neurological and imaging, including SPECT Neuroimaging Analyzes how diet and nutrition effect depression Examines the molecular and cellular effects of depression Covers genetics of depression Includes more than 250 illustrations and tables

Neurobiology of Depression

Joao Luciano de Quevedo,Andre Ferrer Carvalho,Carlos A. Zarate
Neurobiology of Depression Book PDF

Author : Joao Luciano de Quevedo,Andre Ferrer Carvalho,Carlos A. Zarate
Publisher : Academic Press
Page : 471 pages
File Size : 40,5 Mb
Release : 2019-01-03
Category : Medical
ISBN : 9780128133347

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Neurobiology of Depression by Joao Luciano de Quevedo,Andre Ferrer Carvalho,Carlos A. Zarate Pdf

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression

Neurobiology of Depression

Francisco Lopez-Munoz,Cecilio Alamo
Neurobiology of Depression Book PDF

Author : Francisco Lopez-Munoz,Cecilio Alamo
Publisher : CRC Press
Page : 526 pages
File Size : 55,9 Mb
Release : 2011-09-09
Category : Medical
ISBN : 9781439838501

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Neurobiology of Depression by Francisco Lopez-Munoz,Cecilio Alamo Pdf

Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, molecular biology, genomics, psychiatry, psychology, and pharmacology, Neurobiology of Depression discusses the nature of the central nervous system circuits responsible for the modifications of neuronal functioning that lead to depression. The book begins by discussing animal, neurophysiological, and neuropsychological models of depression as well as neural foundations. It explores genetic factors that contribute to depression and describes the effect of monoaminergic systems in the central nervous system. Next, the book profiles the rise of psychopharmacology in the treatment of depression and the research into serotonin and monoamine reuptake inhibitors. It examines the role of the glutamatergic, endocannabinoid, and opioid systems in the pathophysiology of mood disorders, as well as the effect of biological rhythms on the human body. Later chapters review the role of CRF-related ligands, CRF receptors, HPA axis activity, and glucocorticoid receptors in the regulation of the stress response and depression. They also describe cytokine modulation of molecular mechanisms. They examine the role of neuropeptide Y, nitric oxide, beta-arrestins, BDNF, and phosphodiesterases, and discuss the use of tachykinin antagonists in treatment. Finally, they analyze the neurobiological basis for the development of new antidepressant agents. Exploring myriad aspects of a disease that plagues a large percentage of the population worldwide, this volume captures the state of the science of this debilitating disorder, facilitating further research and discovery.

The Upward Spiral

Alex Korb
The Upward Spiral Book PDF

Author : Alex Korb
Publisher : New Harbinger Publications
Page : 232 pages
File Size : 54,9 Mb
Release : 2015-03-01
Category : Self-Help
ISBN : 9781626251229

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The Upward Spiral by Alex Korb Pdf

Depression can feel like a downward spiral, pulling you into a vortex of sadness, fatigue, and apathy. In The Upward Spiral, neuroscientist Alex Korb demystifies the intricate brain processes that cause depression and offers a practical and effective approach to getting better. Based on the latest research in neuroscience, this book provides dozens of straightforward tips you can do every day to rewire your brain and create an upward spiral towards a happier, healthier life. Whether you suffer from depression or just want a better understanding of the brain, this book offers an engaging and informative look at the neuroscience behind our emotions, thoughts, and actions. The truth is that there isn’t one big solution to depression, but there are numerous simple steps you can take to alter brain activity and chemistry. Some are as easy as relaxing certain muscles to reduce anxiety, or getting more sunlight to improve your mood. Small steps in the right direction can have profound effects—giving you the power to become your best self as you literally reshape your brain, one small change at a time.

Vulnerability to Depression

Rick E. Ingram,Ruth Ann Atchley,Zindel V. Segal
Vulnerability to Depression Book PDF

Author : Rick E. Ingram,Ruth Ann Atchley,Zindel V. Segal
Publisher : Guilford Press
Page : 260 pages
File Size : 46,9 Mb
Release : 2011-06-07
Category : Psychology
ISBN : 1609182553

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Vulnerability to Depression by Rick E. Ingram,Ruth Ann Atchley,Zindel V. Segal Pdf

Providing a cutting-edge examination of the mechanisms underlying depression, this volume integrates important areas of research that have largely remained separate. The authors explore both the cognitive and neurological processes that make some people more vulnerable than others to developing depression and experiencing recurrent episodes. They also probe how these processes interact—how negative life experiences, maladaptive belief systems, and patterns of thinking may actually affect neural circuitry, and vice versa. Explaining sophisticated theory and research in an accessible style, the book highlights the implications for improving clinical practices and patient outcomes.

The Neurobiological Basis of Suicide

Yogesh Dwivedi
The Neurobiological Basis of Suicide Book PDF

Author : Yogesh Dwivedi
Publisher : CRC Press
Page : 485 pages
File Size : 53,6 Mb
Release : 2012-06-25
Category : Medical
ISBN : 9781439838815

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The Neurobiological Basis of Suicide by Yogesh Dwivedi Pdf

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

The Neuroscience of Depression

Colin R Martin,Lan-Anh Hunter,Vinood Patel,Victor R Preedy,Rajkumar Rajendram
The Neuroscience of Depression Book PDF

Author : Colin R Martin,Lan-Anh Hunter,Vinood Patel,Victor R Preedy,Rajkumar Rajendram
Publisher : Academic Press
Page : 576 pages
File Size : 47,6 Mb
Release : 2021-03-05
Category : Psychology
ISBN : 9780128179369

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The Neuroscience of Depression by Colin R Martin,Lan-Anh Hunter,Vinood Patel,Victor R Preedy,Rajkumar Rajendram Pdf

The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is a comprehensive reference to the aspects, features and effects of depression. This book provides readers with the behavior and psychopathological effects of depression, linking anxiety, anger and PSTD to depression. Readers are provided with a detailed outline of the genetic aspects of depression including synaptic genes and the genome-wide association studies (GWAS) of depression, followed by a thorough analysis of the neurological and imaging techniques used to study depression. This book also includes three full sections on the various effects of depression, including diet, nutrition and molecular and cellular effects. The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet is the only resource for researchers and practitioners studying depression. Features a section on neurological and imaging, including SPECT Neuroimaging Analyzes how diet and nutrition effect depression Examines the molecular and cellular effects of depression Covers genetics of depression Includes more than 250 illustrations and tables

The Oxford Handbook of Mood Disorders

Robert J. DeRubeis,Daniel R. Strunk
The Oxford Handbook of Mood Disorders Book PDF

Author : Robert J. DeRubeis,Daniel R. Strunk
Publisher : Oxford University Press
Page : 537 pages
File Size : 52,6 Mb
Release : 2017
Category : Psychology
ISBN : 9780199973965

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The Oxford Handbook of Mood Disorders by Robert J. DeRubeis,Daniel R. Strunk Pdf

The most comprehensive volume of its kind, The Oxford Handbook of Mood Disorders provides detailed coverage of the characterization, understanding, and treatment of mood disorders. Chapters are written by the world's leading experts in their respective areas. The Handbook provides coverage of unipolar depression, bipolar disorder, and variants of these disorders. Current approaches to classifying the mood disorders are reviewed and contemporary controversies are placed in historical context. Chapter authors offer a variety of approaches to understanding the heterogeneity of the experiences of those who meet criteria for mood disorders, both within and across cultures. The role of genetic and environmental risk factors as well as premorbid personality and cognitive processes in the development of mood pathology are detailed. Interpersonal, neurobiological, and psychological factors also receive detailed consideration. The volume reviews mood disorders in special populations (e.g., postpartum and seasonal mood disorders) as well as common comorbidities (e.g., anxiety, substance use disorders). Somatic and psychosocial treatment approaches receive in-depth coverage with chapters that describe and review empirical evidence regarding each of the most influential treatment approaches. The depth and breadth offered by this Handbook make it an invaluable resource for clinicians and researchers, as well as scholars and students.

Cognitive-Affective Neuroscience of Depression and Anxiety Disorders

Dan J. Stein
Cognitive Affective Neuroscience of Depression and Anxiety Disorders Book PDF

Author : Dan J. Stein
Publisher : CRC Press
Page : 0 pages
File Size : 43,9 Mb
Release : 2004-08-02
Category : Science
ISBN : 1135416567

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Cognitive-Affective Neuroscience of Depression and Anxiety Disorders by Dan J. Stein Pdf

Data on depression and anxiety disorders now spans a range of fields from molecular neuroscience, through cognitive and affective science, and on to evolutionary psychology. The author here integrates this work into one volume, providing the clinician with a theoretical synthesis as well as a useful practical framework. Cognitive-Affective Neuroscience of Depression and Anxiety Disorders helps professionals in these various fields to manage patients with major depression, generalized anxiety disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder and social anxiety disorder. Neuroscientists, neurologists, pharmacologists, psychiatrists and mental health practitioners will benefit from this text.

Neuropsychology of Depression

Shawn M. McClintock,Jimmy Choi
Neuropsychology of Depression Book PDF

Author : Shawn M. McClintock,Jimmy Choi
Publisher : Guilford Publications
Page : 484 pages
File Size : 41,8 Mb
Release : 2022-02-20
Category : Psychology
ISBN : 9781462549337

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Neuropsychology of Depression by Shawn M. McClintock,Jimmy Choi Pdf

Timely and authoritative, this unique volume focuses on neurocognitive aspects of depression and their implications for assessment, evaluation, clinical management, and research. Experts in the field explore the impact of depression on executive function, learning and memory, working memory, and other critical capacities, and present cutting-edge assessment tools and procedures. The neurocognitive effects of widely used antidepressant treatments are reviewed, from psychotropic medications and evidence-based psychotherapies to established and emerging neuromodulation technologies. Practical aspects of working with adults across the lifespan with depression are addressed, including ways to strengthen treatment engagement and adherence, and to incorporate cultural considerations.

Undoing Depression

Richard O'Connor
Undoing Depression Book PDF

Author : Richard O'Connor
Publisher : Little, Brown Spark
Page : 380 pages
File Size : 46,6 Mb
Release : 2021-09-28
Category : Self-Help
ISBN : 9780316266956

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Undoing Depression by Richard O'Connor Pdf

The bestselling approachable guide that has inspired thousands of readers to manage or overcome depression — fully revised and updated for life in the 21st century. Depression rates around the world have skyrocketed in the 20‑plus years since Richard O'Connor first published his classic book on living with and overcoming depression. Nearly 40 million American adults suffer from the condition, which affects nearly every aspect of life, from relationships, to job performance, physical health, productivity, and, of course, overall happiness. And in an increasingly stressful and overwhelming world, it's more important than ever to understand the causes and effects of depression, and what we can do to overcome it. In this fully revised and updated edition — which includes updated information on the power of mindfulness, the relationship between depression and other diseases, the risks and side effects of medication, depression’s effect on thinking, and the benefits of exercise — Dr. O'Connor explains that, like heart disease and other physical conditions, depression is fueled by complex and interrelated factors: genetic, biochemical, environmental. But Dr. O'Connor focuses on an additional factor that is often overlooked: our own habits. Unwittingly we get good at depression. We learn how to hide it, and how to work around it. We may even achieve great things, but with constant struggle rather than satisfaction. Relying on these methods to make it through each day, we deprive ourselves of true recovery, of deep joy and healthy emotion. Undoing Depression teaches us how to replace depressive patterns with a new and more effective set of skills. We already know how to "do" depression—and we can learn how to undo it. With a truly holistic approach that synthesizes the best of the many schools of thought about this painful disease, and a critical eye toward medications, O'Connor offers new hope—and new life—for sufferers of depression.

The Inflamed Mind

Edward Bullmore
The Inflamed Mind Book PDF

Author : Edward Bullmore
Publisher : Picador
Page : 256 pages
File Size : 55,5 Mb
Release : 2018-12-31
Category : Psychology
ISBN : 9781250318152

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The Inflamed Mind by Edward Bullmore Pdf

As seen on "CBS This Morning" Worldwide, depression will be the single biggest cause of disability in the next twenty years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still...until now with Edward Bullmore's The Inflamed Mind: A Radical New Approach to Depression. A Sunday Times (London) Top Ten Bestseller In this game-changing book, University of Cambridge profressor of psychiatry Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycles of stress, inflammation, and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain, and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into how we could start getting to grips with depression and other mental disorders much more effectively in the future.

The Upward Spiral Workbook

Alex Korb
The Upward Spiral Workbook Book PDF

Author : Alex Korb
Publisher : New Harbinger Publications
Page : 268 pages
File Size : 48,5 Mb
Release : 2019-04-01
Category : Self-Help
ISBN : 9781684032440

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The Upward Spiral Workbook by Alex Korb Pdf

Positive life changes lead to positive brain changes. Drawing on the huge success of his groundbreaking book, The Upward Spiral, neuroscientist Alex Korb offers actionable, step-by-step skills to help you reshape your brain and create an upward spiral towards a happier, healthier life. Depression is defined by a collection of symptoms. You feel crappy most of the time. Nothing seems interesting, and everything seems overwhelming. You have trouble with sleep. You feel guilty and anxious and have thoughts that life isn’t worth living. Each symptom reinforces and inspires new symptoms, and this is a sign that your brain circuits are caught in the downward spiral of depression. So, how can you reverse it? In his first book, The Upward Spiral, neuroscientist Alex Korb demystified the intricate brain processes that cause depression and outlined a practical and effective approach for getting better. Based on the latest research, this evidence-based workbook takes the theory behind Korb’s breakthrough book and distills it into concrete, actionable exercises and skills. Just as one small trigger can drag you down, an effective intervention can start enough momentum to carry you back up. Exercise, attention to breathing, gratitude, sleep hygiene, and positive social interactions are just some of the offerings in this workbook that can help alter activity in specific neural circuits, setting you on the path toward an upward spiral to happiness and well-being.