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Author : Francis Otto Schmitt
Publisher : Unknown
Page : 1096 pages
File Size : 42,9 Mb
Release : 1970
Category : Science
ISBN : UOM:39015004441013
Author : John S. Werner,Leo M. Chalupa
Publisher : MIT Press
Page : 1693 pages
File Size : 51,6 Mb
Release : 2013-10-25
Category : Science
ISBN : 9780262019163
A comprehensive review of contemporary research in the vision sciences, reflecting the rapid advances of recent years. Visual science is the model system for neuroscience, its findings relevant to all other areas. This essential reference to contemporary visual neuroscience covers the extraordinary range of the field today, from molecules and cell assemblies to systems and therapies. It provides a state-of-the art companion to the earlier book The Visual Neurosciences (MIT Press, 2003). This volume covers the dramatic advances made in the last decade, offering new topics, new authors, and new chapters. The New Visual Neurosciences assembles groundbreaking research, written by international authorities. Many of the 112 chapters treat seminal topics not included in the earlier book. These new topics include retinal feature detection; cortical connectomics; new approaches to mid-level vision and spatiotemporal perception; the latest understanding of how multimodal integration contributes to visual perception; new theoretical work on the role of neural oscillations in information processing; and new molecular and genetic techniques for understanding visual system development. An entirely new section covers invertebrate vision, reflecting the importance of this research in understanding fundamental principles of visual processing. Another new section treats translational visual neuroscience, covering recent progress in novel treatment modalities for optic nerve disorders, macular degeneration, and retinal cell replacement. The New Visual Neurosciences is an indispensable reference for students, teachers, researchers, clinicians, and anyone interested in contemporary neuroscience. Associate Editors Marie Burns, Joy Geng, Mark Goldman, James Handa, Andrew Ishida, George R. Mangun, Kimberley McAllister, Bruno Olshausen, Gregg Recanzone, Mandyam Srinivasan, W.Martin Usrey, Michael Webster, David Whitney Sections Retinal Mechanisms and Processes Organization of Visual Pathways Subcortical Processing Processing in Primary Visual Cortex Brightness and Color Pattern, Surface, and Shape Objects and Scenes Time, Motion, and Depth Eye Movements Cortical Mechanisms of Attention, Cognition, and Multimodal Integration Invertebrate Vision Theoretical Perspectives Molecular and Developmental Processes Translational Visual Neuroscience
Author : F. WORDEN,J. SWAZEY,G. ADELMAN
Publisher : Springer Science & Business Media
Page : 627 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468468175
To commemorate properly the 70th birthday of a man who, by his very nature, is too busy to pause for any kind of ceremonial event unless it has a concomitant functional output was a difficult problem for the Staff and Associates of the Neurosciences Research Program. Frank (F. O. S. ) has always dreaded the prospect that sometime it might be appropriate for his colleagues to present him a Fest schrift. In fact, "Fest me no Schriften" became his battle cry, expressing his feeling that the idea of testimonials clustered into a book was anathema. So the "break through" idea for the planners was to organize a symposium around the theme of discovery in neuroscience that would be valuable scientifically and, in its demon stration of interdisciplinary interaction, would support that emphasis in Frank's career. After much planning a program was developed, beginning with a birthday party the evening before, followed by the two-day symposium, and closing with the first F. O. Schmitt Lecture in Neuroscience. We hope that publication of the scientific proceedings in this volume will be of interest not only to the neuroscience community, but also to a broad general readership interested in discovery, under standing, and the creative processes in scientific work. An organizing committee, chaired by Fred Worden, collected advice and guidance leading to the selection of speakers whose scientific careers have played an important part in the recent history of modern neuroscience.
Author : Daniel H. Geschwind,Jeffrey P. Gregg
Publisher : MIT Press
Page : 366 pages
File Size : 48,9 Mb
Release : 2002
Category : DNA microarrays
ISBN : 0262072297
The effort to sequence the human genome has generated a new discipline, functional genomics, or the study of the relationship between the genetic code and its biologic potential. Gene expression studies are made possible not only by the decoding of the human genome, but by the development of new technologies. The preeminent technology in this area, DNA microarrays, is helping to revolutionize the field of neuroscience.
Author : Katherine M. Woodbury-Harris,Bruce M. Coull
Publisher : Karger Medical and Scientific Publishers
Page : 225 pages
File Size : 53,5 Mb
Release : 2009
Category : Medical
ISBN : 9783805590235
A properly designed and executed clinical trial that addresses an import question and delivers a definitive result can change the practice of medicine worldwide. This book encompasses a bench-to-bedside approach and serves as an excellent guidance for translating preclinical studies to early phase I/II and phase III trials. In the first part, the book covers preclinical science with respect to animal models of various neurological diseases, FDA requirements for preclinical studies, translation of animal to patient studies and scaling up from animal to human studies. In the second part, the design of phase I/II trials and the use of biomarkers as surrogate endpoints are discussed. With regard to phase III trials, FDA and European requirements, specific design issues, relevant clinical endpoints as well as data management and quality are examined. Topics specific to multicenter trials, such as design, recruitment of special populations, monitoring, ethical and consent issues are also covered. Finally, genetics, gene therapy, imaging and surgical devices are reviewed.This publication is highly recommended to clinician researchers, such as neurologists, neurosurgeons, pediatric neurologists and neonatologists, who want to design and conduct clinical trials in the neuroscience, but also to nurses, research coordinators and clinical pharmacologists.
Author : Jane Bottenstein
Publisher : Springer Science & Business Media
Page : 392 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461324737
A fundamental problem in neuroscience is the elucidation of the cellular and molecular mechanisms underlying the development and function of the nervous system. The complexity of organization, the heteroge neity of cell types and their interactions, and the difficulty of controlling experimental variables in intact organisms make this a formidable task. Because of the ability that it affords to analyze smaller components of the nervous system (even single cells in some cases) and to better control experimental variables, cell culture has become an increasingly valuable tool for neuroscientists. Many aspects of neural development, such as proliferation, differentiation, synaptogenesis, and myelination, occur in culture with time courses remarkably similar to those in vivo. Thus, in vitro methods often provide excellent model systems for investigating neurobiological questions. Ross Harrison described the first culture of neural tissue in 1907 and used morphological methods to analyze the cultures. Since that time the technique has been progressively modified and used to address an ever widening range of developmental questions. In recent years a con vergence of new or improved cell culture, biochemical, electrophysiol ogical, and immunological methods has occurred and been brought to bear on neurobiological questions. This volume is intended not to be comprehensive but rather to highlight some of the latest findings, with a review of previous important work as well, in which combinations of these methods are used.
Author : Konrad Akert
Publisher : vdf Hochschulverlag AG
Page : 96 pages
File Size : 55,7 Mb
Release : 1996
Category : Neurosciences
ISBN : 3728123625
Author : Peter Machamer,Rick Grush,Peter McLaughlin
Publisher : University of Pittsburgh Press
Page : 309 pages
File Size : 52,5 Mb
Release : 2024-06-01
Category : Philosophy
ISBN : 9780822959465
Theory and Method in the Neurosciences surveys the nature and structure of theories in contemporary neuroscience, exploring many of its methodological techniques and problems. The essays explore basic questions about how to relate theories of neuroscience and cognition, the multilevel character of such theories, and their experimental bases. Philosophers and scientists (and some who are both) examine the topics of explanation and mechanisms, simulation and computation, imaging and animal models that raise questions about the forefront of research in cognitive neuroscience. Their work will stimulate new thinking in anyone interested in the mind or brain and in recent theories of their connections.
Author : Michael S. Gazzaniga
Publisher : MIT Press
Page : 1377 pages
File Size : 44,6 Mb
Release : 2009-09-18
Category : Psychology
ISBN : 9780262013413
"The fourth edition of The Cognitive Neurosciences continues to chart new directions in the study of the biologic underpinnings of complex cognition - the relationship between the structural and physiological mechanisms of the nervous system and the psychological reality of the mind. The material in this edition is entirely new, with all chapters written specifically for it." --Book Jacket.
Author : William Bechtel,Pete Mandik,Jennifer Mundale,Robert Stufflebeam
Publisher : Wiley-Blackwell
Page : 496 pages
File Size : 53,7 Mb
Release : 2001-10-08
Category : Science
ISBN : 0631210458
By introducing key themes in philosophy of mind, philosophy of science and the basic concepts of neuroscience, this text provides philosophers with the necessary background to engage the neurosciences and offers neuroscientists an introduction to the relevant tools of philosophical analysis.
Author : F. Callard,D. Fitzgerald
Publisher : Springer
Page : 157 pages
File Size : 46,7 Mb
Release : 2015-12-30
Category : Psychology
ISBN : 9781137407962
This book offers a provocative account of interdisciplinary research across the neurosciences, social sciences and humanities. Rooting itself in the authors' own experiences, the book establishes a radical agenda for collaboration across these disciplines. This book is open access under a CC-BY license.
Author : Anthony David Smith,Platon Grigorʹevich Kosti︠u︡k,Rodolfo Riascos Llinás
Publisher : Pergamon
Page : 716 pages
File Size : 48,6 Mb
Release : 1980
Category : Science
ISBN : STANFORD:36105031540532
Commentaries in the Neurosciences ...
Author : Matt Carter,Rachel Essner,Nitsan Goldstein,Manasi Iyer
Publisher : Academic Press
Page : 416 pages
File Size : 52,7 Mb
Release : 2022-03-26
Category : Medical
ISBN : 9780323915618
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step
Author : G N Reeke,R R Poznanski,O. Sporns,K A Lindsay,J R Rosenberg
Publisher : CRC Press
Page : 736 pages
File Size : 42,8 Mb
Release : 2019-08-30
Category : Electronic
ISBN : 0367393174
Computational models of neural networks have proven insufficient to accurately model brain function, mainly as a result of simplifications that ignore the physical reality of neuronal structure in favor of mathematically tractable algorithms and rules. Even the more biologically based "integrate and fire" and "compartmental" styles of modeling suffer from oversimplification in the former case and excessive discretization in the second. This book introduces an integrative approach to modeling neurons and neuronal circuits that retains the integrity of the biological units at all hierarchical levels. With contributions from more than 40 renowned experts, Modeling in the Neurosciences, Second Edition is essential for those interested in constructing more structured and integrative models with greater biological insight. Focusing on new mathematical and computer models, techniques, and methods, this book represents a cohesive and comprehensive treatment of various aspects of the neurosciences from the molecular to the network level. Many state-of-the-art examples illustrate how mathematical and computer modeling can contribute to the understanding of mechanisms and systems in the neurosciences. Each chapter also includes suggestions of possible refinements for future modeling in this rapidly changing and expanding field. This book will benefit and inspire the advanced modeler, and will give the beginner sufficient confidence to model a wide selection of neuronal systems at the molecular, cellular, and network levels.
Author : Flavio Fröhlich
Publisher : Academic Press
Page : 482 pages
File Size : 49,5 Mb
Release : 2016-09-20
Category : Medical
ISBN : 9780128015865
Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. Network Neuroscience is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader’s background. Dr. Flavio Frohlich (www.networkneuroscientist.org) wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab (www.frohlichlab.org) pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology. Easy-to-read, comprehensive introduction to the emerging field of network neuroscience Includes 27 chapters packed with information on topics from single neurons to complex network disorders such as depression and autism Features 12 toolboxes serve as primers to provide essential background knowledge in the fields of biology, mathematics, engineering, and physics