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Author : A.P. Wolffe
Publisher : Elsevier
Page : 249 pages
File Size : 49,8 Mb
Release : 1996-01-08
Category : Science
ISBN : 0080537847
This is the first in a series of volumes concerning the properties of the eukaryotic nucleus. Contributions from several of the most active laboratories are brought together to present a focused overview of a selected aspect of nuclear structure and function.
Author : Benjamin Lewin
Publisher : Jones & Bartlett Learning
Page : 918 pages
File Size : 47,7 Mb
Release : 2007
Category : Science
ISBN : 0763739057
"CELLS, the most cutting-edge textbook in the field, is the ideal resource for advanced undergraduate and graduate students entering the world of cell biology, and is a useful tool for scientists who wish to learn more about topics outside their field. This important new text provides full coverage of the structure, organization, growth, regulation, movements, and interaction of cells, with an emphasis on eukaryotic cells. Where they are known, the molecular bases for human diseases are discussed in each chapter.Under the direction of Dr. Benjamin Lewin and three expert lead editors, each chapter was prepared by top scientists who specialize in the subject area. All chapters were carefully edited to maintain consistent use of terminology and to achieve a homogeneous level of detail and rigor."--Publisher's website.
Author : Jocelyn E. Krebs,Elliott S. Goldstein,Stephen T. Kilpatrick
Publisher : Jones & Bartlett Publishers
Page : 957 pages
File Size : 54,5 Mb
Release : 2009-11-27
Category : Medical
ISBN : 9780763782375
The fields of molecular biology and molecular genetics is rapidly changing with new data acquired daily and new insights into well-studied processes presented on a scale of weeks or months rather than years. For decades Lewin's GENES has provided the teaching community with the most cutting edge presentation of molecular biology and molecular genetics, covering gene structure, sequencing, organization, and expression. The latest edition, with a knowledgeable new author team, has enlisted 21 scientists to provide revisions and content updates in their individual fields of expertise, ensuring that Lewin's GENES X is the most current and comprehensive text in the field. Informative new chapters, as well as a reorganization of material, provide a more logical flow of topics and many chapters have been renamed to better indicate their contents. Lewin's GENES X also contains new pedagogical features to help students learn as they read and an online student study guide allows students to test themselves on key material.
Author : Karsten Rippe
Publisher : John Wiley & Sons
Page : 597 pages
File Size : 44,8 Mb
Release : 2011-12-19
Category : Science
ISBN : 9783527326983
By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.
Author : Carl Wu,C. David Allis
Publisher : Academic Press
Page : 430 pages
File Size : 55,6 Mb
Release : 2012
Category : Basic proteins
ISBN : 9780123919380
Covers nucleosomes, histones and chromatin, with chapters on dynamic mapping of histone-DNA interactions in nucleosomes by unzipping single molecules of DNA, Digital DNase technology, and Genome-wide Analysis of Chromatin Transition.
Author : S. Rosenthal,H. Bielka,Ch. Coutelle
Publisher : Elsevier
Page : 565 pages
File Size : 41,5 Mb
Release : 2014-05-09
Category : Science
ISBN : 9781483188515
Gene Function, contains the proceedings of the 12th Meeting of the Federation of European Biochemical Societies held in Dresden, Germany in 1978. The meeting provided a forum for discussing progress in the understanding of gene function and covered topics ranging from the functional organization of chromatin to principles of interactions and recognition models. The role of DNA sequence in the recognition of restriction endonucleases and modification enzymes is also examined, along with gene expression, RNA processing and modification, and isolation and synthesis of genes. Comprised of 49 chapters, this volume begins with an overview of what can be learned from the genetic analysis of the lac repressor, followed by a discussion on the topography of the interaction the lac repressor, RNA polymerase, and histones with DNA. The reader is then introduced to complementarity and recognition code between regulatory proteins and DNA; chromatin replication in vitro; and the cytoplasmic "petite" mutation in Saccharomyces cerevisiae. Subsequent chapters explore arc-like and helical arrangements of nucleosome cores; changes in gene expression during cellular differentiation; polyadenylation and processing of pre-messenger RNA; and the molecular biology of bacteriophages T3 and T7. This book will be of interest to geneticists, biochemists, and molecular biologists.
Author : George Plopper,David Sharp,Eric Sikorski
Publisher : Jones & Bartlett Publishers
Page : 1080 pages
File Size : 41,6 Mb
Release : 2013-12-02
Category : Medical
ISBN : 9781284023565
Ideal text for undergraduate and graduate students in advanced cell biology courses Extraordinary technological advances in the last century have fundamentally altered the way we ask questions about biology, and undergraduate and graduate students must have the necessary tools to investigate the world of the cell. The ideal text for students in advanced cell biology courses, Lewin's CELLS, Third Edition continues to offer a comprehensive, rigorous overview of the structure, organization, growth, regulation, movements, and interactions of cells, with an emphasis on eukaryotic cells. The text provides students with a solid grounding in the concepts and mechanisms underlying cell structure and function, and will leave them with a firm foundation in cell biology as well as a "big picture" view of the world of the cell. Revised and updated to reflect the most recent research in cell biology, Lewin's CELLS, Third Edition includes expanded chapters on Nuclear Structure and Transport, Chromatin and Chromosomes, Apoptosis, Principles of Cell Signaling, The Extracellular Matrix and Cell Adhesion, Plant Cell Biology, and more. All-new design features and a chapter-by-chapter emphasis on key concepts enhance pedagogy and emphasize retention and application of new skills. Thorough, accessible, and essential, Lewin's CELLS, Third Edition, turns a new and sharper lens on the fundamental units of life
Author : Timothy R. Hughes
Publisher : Springer Science & Business Media
Page : 310 pages
File Size : 42,6 Mb
Release : 2011-05-10
Category : Medical
ISBN : 9789048190690
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
Author : E. Morton Bradbury,Sándor Pongor
Publisher : Springer Science & Business Media
Page : 332 pages
File Size : 48,6 Mb
Release : 1999-08-31
Category : Medical
ISBN : 0792357817
Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide approaches are needed to draw together the knowledge that is emerging simultaneously in a number of fields of genome research. This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research. Topics included are chromosome and chromatin organisation, novel DNA and RNA structures, DNA flexibility, supercoiling, prediction of protein functions, strategies for large scale structural analysis, and computer modelling.
Author : Laxmi Narayan Mishra,Christophe Thiriet,Dileep Vasudevan
Publisher : Frontiers Media SA
Page : 171 pages
File Size : 50,5 Mb
Release : 2022-11-30
Category : Science
ISBN : 9782832507858
Author : Gerald M. Kolodny
Publisher : CRC Press
Page : 326 pages
File Size : 49,6 Mb
Release : 2018-01-18
Category : Medical
ISBN : 9781351088831
The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.
Author : William M. Brown,Philip M. Brown
Publisher : CRC Press
Page : 172 pages
File Size : 46,7 Mb
Release : 2001-09-20
Category : Science
ISBN : 0415271991
Knowledge of transcription has moved forward at a furious pace over recent years, and an understanding of the processes involved in gene regulation and expression has become an essential element in biochemistry, genome biology, molecular biology and molecular genetics. In this timely book, the authors present an accessible, yet comprehensive, coverage suitable for students at a senior undergraduate level, and for postgraduates needing an overview of the current state of play. It covers a number of pertinent examples of transcription systems for eukaryotes and prokaryotes, indicates methods for studying transcription, and surveys the whole topic of transcription from many perspectives.
Author : Kiichi Fukui,Tatsuo Ushiki
Publisher : CRC Press
Page : 288 pages
File Size : 51,7 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781420044928
Despite progress in genetic research, knowledge about the exact structure of the chromosome continues to provide a challenge. Much of that challenge lies with the need for improved tools and methods that researchers require to perform novel analyses beyond the DNA level. Fortunately, rapid advances in nanotechnology, are now being employed to exami
Author : Anonim
Publisher : Elsevier
Page : 8639 pages
File Size : 45,5 Mb
Release : 2017-12-01
Category : Science
ISBN : 9780081006122
Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts
Author : Anonim
Publisher : Academic Press
Page : 246 pages
File Size : 46,8 Mb
Release : 1981-05-19
Category : Medical
ISBN : 0080863132
Progress in Nucleic Acid Research and Molecular Biology
