The Physiology Of Bioelectricity In Development Tissue Regeneration And Cancer
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The Physiology of Bioelectricity in Development, Tissue Regeneration and Cancer by Christine E. Pullar Pdf
Recent advances in technology have led to the unprecedented accuracy in measurements of endogenous electric fields around sites of tissue disruption. State-of-the-art molecular approaches demonstrate the role of bioelectricity in the directionality and speed of cell migration, proliferation, apoptosis, differentiation, and orientation. New informat
Regenerative Engineering and Developmental Biology by David M. Gardiner Pdf
Regenerative Engineering and Developmental Biology: Principles and Applications examines cutting-edge developments in the field of regenerative engineering. Specific attention is given to activities that embrace the importance of integrating developmental biology and tissue engineering, and how this can move beyond repairing damage to body parts to instead regenerate tissues and organs. The text furthermore focusses on the five legs of the field of regenerative engineering, including: materials, developmental biology, stem cells, physics, and clinical translation. This book was written by leading developmental biologists; each chapter examines the processes that these biologists study and how they can be advanced by using the tools available in tissue engineering/biomaterials. Individual chapters are complete with concluding remarks and thoughts on the future of regenerative engineering. A list of references is also provided to aid the reader with further research. Ultimately, this book achieves two goals. The first encourages the biomedical community to think about how inducing regeneration is an engineering problem. The second goal highlights the discoveries with animal regeneration and how these processes can be engineered to regenerate body parts. Regenerative Engineering and Developmental Biology: Principles and Applications was written with undergraduate and graduate-level biomedical engineering students and biomedical professionals in mind.
If you or someone you love has been diagnosed with cancer, you want to do everything possible to beat the disease. But with so much conflicting advice and so many options available, how do you decide on the best treatment plan for you? In this major new book, Professor Jane Plant and Professor Mustafa Djamgoz present a clear and scientifically sound 10-step programme to help you beat cancer. At a time when you may be feeling helpless and confused, this book provides the essential guidance you need to take control of your life and regain your health with targeted advice for specific cancers. Included in the 10-step plan: · Inform yourself: understand what cancer is, what causes it and how to avoid carcinogens · Choosing the right treatment: evidence-based advice on conventional and complementary therapies, including chemotherapy, radiotherapy, surgery and medication · Change your lifestyle: guidance on diet, exercise, reducing stress, relationships and other lifestyle factors that have a proven link with cancer Beat Cancer will help you prevent cancer, tackle your diagnosis and stay in remission.
Targets of Cancer Diagnosis and Treatment by Christian Stock,Luis A. Pardo Pdf
This third and final volume in the "Ion Transport in Tumor Biology" collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application. As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.
Science journalist Sally Adee breaks open the field of bioelectricity—the electric currents that run through our bodies and every living thing—its misunderstood history, and why new discoveries will lead to new ways around antibiotic resistance, cleared arteries, and new ways to combat cancer. You may be familiar with the idea of our body's biome: the bacterial fauna that populate our gut and can so profoundly affect our health. In We Are Electric we cross into new scientific understanding: discovering your body's electrome. Every cell in our bodies—bones, skin, nerves, muscle—has a voltage, like a tiny battery. It is the reason our brain can send signals to the rest of our body, how we develop in the womb, and why our body knows to heal itself from injury. When bioelectricity goes awry, illness, deformity, and cancer can result. But if we can control or correct this bioelectricity, the implications for our health are remarkable: an undo switch for cancer that could flip malignant cells back into healthy ones; the ability to regenerate cells, organs, even limbs; to slow aging and so much more. The next scientific frontier might be decrypting the bioelectric code, much the way we did the genetic code. Yet the field is still emerging from two centuries of skepticism and entanglement with medical quackery, all stemming from an 18th-century scientific war about the nature of electricity between Luigi Galvani (father of bioelectricity, famous for shocking frogs) and Alessandro Volta (inventor of the battery). In We Are Electric, award-winning science writer Sally Adee takes readers through the thrilling history of bioelectricity and into the future: from the Victorian medical charlatans claiming to use electricity to cure everything from paralysis to diarrhea, to the advances helped along by the giant axons of squids, and finally to the brain implants and electric drugs that await us—and the moral implications therein. The bioelectric revolution starts here.
Bioengineering and Biophysical Aspects of Electromagnetic Fields, Fourth Edition by Ben Greenebaum,Frank Barnes Pdf
The two volumes of this new edition of the Handbook cover the basic biological, medical, physical, and electrical engineering principles. They also include experimental results concerning how electric and magnetic fields affect biological systems—both as potential hazards to health and potential tools for medical treatment and scientific research. They also include material on the relationship between the science and the regulatory processes concerning human exposure to the fields. Like its predecessors, this edition is intended to be useful as a reference book but also for introducing the reader to bioelectromagnetics or some of its aspects. FEATURES • New topics include coverage of electromagnetic effects in the terahertz region, effects on plants, and explicitly applying feedback concepts to the analysis of biological electromagnetic effects • Expanded coverage of electromagnetic brain stimulation, characterization and modeling of epithelial wounds, and recent lab experiments on at all frequencies • Section on background for setting standards and precautionary principle • Discussion of recent epidemiological, laboratory, and theoretical results; including: WHO IARC syntheses of epidemiological results on both high and low frequency fields, IITRI lab study of cancer in mice exposed to cell phone-like radiation, and other RF studies • All chapters updated by internationally acknowledged experts in the field
Dosimetry in Bioelectromagnetics by Marko Markov Pdf
Dosimetry refers to the calculation and assessment of the radiation dose received by the human body. The proposed book will place emphasis on the existence of physical and biophysical dosimetry. It will be discussed for the proper description and evaluation of the signal at the power generation system. It will cover in detail 10 different parameters of EMF (electromagnetism) exposure such as amplitude, frequency, vector, time of exposure, orientation, etc. In most published papers, these parameters are not well defined.
Digital Human Modeling and Medicine by Gunther Paul,Mohamed H. Doweidar Pdf
Digital Human Modeling and Medicine: The Digital Twin explores the body of knowledge and state-of-the-art in Digital Human Modeling (DHM) and its applications in medicine. DHM is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone or integrated with other computerized object design systems to both design or study designs of medical devices or medical device products and their relationship with humans. They serve as fast and cost-efficient computer-based tools for the assessment of human functional systems and human-system interaction. This book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing body functional elements and organs, organ interactions and fields of application. Thus, DHM tools and a specific scientific/practical problem – functional study of the human body – are linked in a coherent framework. Eventually the book shows how DHM interfaces with common physical devices in medical practice, answering to a gap in literature and a common practitioner question. Case studies provide the applied knowledge for practitioners to make informed decisions. A non-specialist level, up-to-date overview and introduction to all medically relevant DHM systems to inform trialing, procurement decisions and initial application Includes user-level examples and case studies of DHM applications in various medical fields Clearly structured and focused compendium that is easy to access, read and understand
Electric Field by Mohsen Sheikholeslami Kandelousi Pdf
In the present book, various applications of electric field are introduced in health and biology like treating cancer and cell sorting and in engineering and technological applications like enhancing the heat transfer, colloidal hydrodynamics and stability, and lithography. Electric field is defined as a force field arising from the electric charges. Depending on the nature of the material (the ability to polarize) and the inherent or attained surface charges, the response of the electric field varies.
Engineering Biomaterials for Neural Applications by Elisa López-Dolado,María Concepción Serrano Pdf
This book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to cure them. The interdisciplinary nature of this book makes it a perfect candidate for the interest of a broad audience, from clinicians working on neural diseases to scientists whose work focuses on the nervous tissue (neuroscientists) and/or materials science. Undergraduate and PhD students can also benefit from the knowledge and discussion included in this book.
Epidemiology of Electromagnetic Fields by Martin Roosli Pdf
Appeals to a Wide Audience Fueled by more than 30 years of intensive research and debate on the impact of electromagnetic fields (EMF) on everyday life—starting with residential exposure to magnetic fields and the development of childhood cancer in the 70s and continuing with risk of exposure via wireless communications in present day—Epidemiology of Electromagnetic Fields addresses ongoing public and scientific controversy surrounding the possible effects of electromagnetic fields (EMF) to human health, and provides an in-depth introduction into the methodology of environmental epidemiology that is appropriate for all levels, from student to practicing engineer. Exposure to EMF Focusing primarily on EMF examples, the author presents the general principles and methodological concepts in environmental epidemiology. Topics of importance in the first part of the book include epidemiological study designs, exposure assessment methods and implications for the study results, as well as selection bias, confounding, and other biases including reverse causality and ecological fallacy. The second part of the book covers environmental epidemiological methods in detail and outlines key examples such as childhood leukemia and exposure to extremely low-frequency magnetic fields, as well as examples that look at brain tumors and mobile phone use. The book also offers a detailed discussion on the range of EMF sources and exposures. In addition, it highlights the sophisticated assessment methods required to address exposure situations, and provides a historical perspective. The third part of the book examines how EMF exposure from the use of wireless communication techniques and other challenges affect risk assessment today and also details future developments. Explores environmental epidemiological methods in detail, while critically discussing epidemiological findings Provides a state-of-the-art overview of the scientific evidence of the health effects of EMF Considers how novelty, the steep increase of radiofrequency (RF) EMF exposure from wireless communications, and other challenges affect risk assessment today Epidemiology of Electromagnetic Fields provides a thorough overview of the subject, and evaluates the scientific evidence surrounding the possible health effects of EMFs.
Conductive Polymers by Ze Zhang,Mahmoud Rouabhia,Simon E. Moulton Pdf
This book is dedicated to the field of conductive polymers, focusing on electrical interactions with biological systems. It addresses the use of conductive polymers as the conducting interface for electrical communications with the biological system, both in vitro and in vivo. It provides an overview on the chemistry and physics of conductive polymers, their useful characteristics as well as limitations, and technologies that apply conductive polymers for medical purposes. This groundbreaking resource addresses cytotoxicity and tissue compatibility of conductive polymers, the basics on electromagnetic fields, and commonly used experimental methods. Readers will also learn how cells are cultured in vitro with conductive polymers, and how conductive polymers and living tissues interact electrically. Throughout the contents, chapter authors emphasize the importance of conductive polymers in biomedical engineering and their potential applications in medicine.
Electromagnetic Fields in Biological Systems by James C. Lin Pdf
Spanning static fields to terahertz waves, this volume explores the range of consequences electromagnetic fields have on the human body. Topics discussed include essential interactions and field coupling phenomena; electric field interactions in cells, focusing on ultrashort, pulsed high-intensity fields; dosimetry or coupling of ELF fields into biological systems; and the historical developments and recent trends in numerical dosimetry. It also discusses mobile communication devices and the dosimetry of RF radiation into the human body, exposure and dosimetry associated with MRI and spectroscopy, and available data on the interaction of terahertz radiation with biological tissues, cells, organelles, and molecules.
Advanced Electroporation Techniques in Biology and Medicine by Andrei G. Pakhomov,Damijan Miklavcic,Marko S. Markov Pdf
A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last decades, Advanced Electroporation Techniques in Biology and Medicine summarizes most recent experimental findings and theories related to permeabilization of biomembranes by pulsed electric fields. Edited by experts and
Biological and Medical Aspects of Electromagnetic Fields, Fourth Edition by Ben Greenebaum,Frank Barnes Pdf
The two volumes of this new edition of the Handbook cover the basic biological, medical, physical, and electrical engineering principles. They also include experimental results concerning how electric and magnetic fields affect biological systems—both as potential hazards to health and potential tools for medical treatment and scientific research. They also include material on the relationship between the science and the regulatory processes concerning human exposure to the fields. Like its predecessors, this edition is intended to be useful as a reference book but also for introducing the reader to bioelectromagnetics or some of its aspects. FEATURES • New topics include coverage of electromagnetic effects in the terahertz region, effects on plants, and explicitly applying feedback concepts to the analysis of biological electromagnetic effects • Expanded coverage of electromagnetic brain stimulation, characterization and modeling of epithelial wounds, and recent lab experiments on at all frequencies • Section on background for setting standards and precautionary principle • Discussion of recent epidemiological, laboratory, and theoretical results; including: WHO IARC syntheses of epidemiological results on both high and low frequency fields, IITRI lab study of cancer in mice exposed to cell phone-like radiation, and other RF studies • All chapters updated by internationally acknowledged experts in the field