The Pineal Gland And Cancer

Author : C. Bartsch,H. Bartsch,D.E. Blask,D.P. Cardinali,W.J.M. Hrushesky,Dieter Mecke
Publisher : Springer Science & Business Media
Page : 979 pages
File Size : 52,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642595127

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The Pineal Gland and Cancer by C. Bartsch,H. Bartsch,D.E. Blask,D.P. Cardinali,W.J.M. Hrushesky,Dieter Mecke Pdf

The link between the pineal gland and cancer is a rapidly emerging research field due to promising experimental and clinical trials with melatonin. The pineal gland acts as a transducer of environmental light to regulate rhythmic processes, including reproductive function in seasonally breeding animals and the entrainment of circadian rhythms, such as the sleep-wake cycle, in man. This book elucidates the physiological significance of the pineal gland and surveys phenomena and mechanisms of pineal - tumor interaction at the neuroendocrine, neuroimmune, neural, and molecular levels. Yet unidentified low-molecular-weight pineal substances with tumor-inhibiting capacity, a possible involvement of melatonin in electromagnetic field effects on cancer, and the oncotherapeutic potential of melatonin are also addressed. The encouraging results should incite further research to elucidate the exact nature of the link between the pineal gland and cancer for the benefit of patients.

Author : Derek Gupta,Russel J. Reiter,Andrea Attanasio
Publisher : Unknown
Page : 389 pages
File Size : 53,8 Mb
Release : 1988
Category : Cancer
ISBN : 3980160505

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The Pineal Gland and Cancer by Derek Gupta,Russel J. Reiter,Andrea Attanasio Pdf

Author : Edward A. Neuwelt
Publisher : Unknown
Page : 424 pages
File Size : 51,6 Mb
Release : 1984
Category : Medical
ISBN : UOM:39015006707320

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Diagnosis and Treatment of Pineal Region Tumors by Edward A. Neuwelt Pdf

Author : Henry H. Schmidek
Publisher : Unknown
Page : 160 pages
File Size : 42,6 Mb
Release : 1977
Category : Medical
ISBN : UOM:39015000302284

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Pineal Tumors by Henry H. Schmidek Pdf

Author : Franco Fraschini,Russel J. Reiter,Bojidar Stankov
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 44,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461519119

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The Pineal Gland and Its Hormones by Franco Fraschini,Russel J. Reiter,Bojidar Stankov Pdf

This volume contains the written contributions to the proceedings of a workshop related to the pineal gland and its hormones, which was held in Erice, Italy, on June 7 -June 13, 1994. This series of workshops, which began in 1982 and which have been held at four-year intervals since that time, has provided important continuity for advancing the state of knowledge relating to this very important investigative area. The enthusiasm for these conferences has increased steadily, as reflected in the number of individuals applying to attend and in the input of individuals who participate in the meeting. The 1994 meeting was important because of its timeliness. In the two years preceding the meeting a number of revolutionary discoveries were made relative to the actions of the pineal hormone melatonin. The Xenopus melatonin receptor was cloned, melatonin was demonstrated to be a potent antioxidant, the significance of melatonin receptors at the level of pars tuberalis in the regulation of the hypothalamo-pituitary-gonadal axis was questioned, a number of melatonin receptor analogues were discovered and successfully utilized, the mechanisms by which melatonin retards initiation and promotion of cancer was further elucidated, the clinical aspects of the pineal gland was re-scrutinized. Reviews relating to each of these subjects, as well as many others, are contained in this proceedings book. This volume represents an up-to-date repository for the most recent information related to this rapidly advancing field.

Author : Tatsuya Kobayashi,L. Dade Lunsford
Publisher : Karger Medical and Scientific Publishers
Page : 153 pages
File Size : 45,6 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9783805590778

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Pineal Region Tumors by Tatsuya Kobayashi,L. Dade Lunsford Pdf

The pineal region is an anatomic location where various intracranial tumors, in particular germ cell tumors and pineal parenchymal tumors, occur. Interestingly, pineal germ cell tumors are detected more frequently in Asian countries, including Japan, while pineal parenchymal tumors are less frequent in Asia than in the United States and Europe. This publication takes advantage of the knowledge and experience of Japanese experts in pineal tumors, with emphasis on epidemiology and pathological diagnosis. A variety of treatment modalities including radiotherapy, radiosurgery, surgical therapy and chemotherapy are also discussed. This valuable book will enhance the knowledge on pineal tumor treatment of not only neurosurgeons and radiation oncologists but also neurologists, neuro-oncologists, pediatricians and neuropathologists interested in pineal region tumors.

Author : Josephine Arendt
Publisher : Springer Science & Business Media
Page : 364 pages
File Size : 51,5 Mb
Release : 1994-12-31
Category : Science
ISBN : 0412536005

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Melatonin and the Mammalian Pineal Gland by Josephine Arendt Pdf

This volume provides the reader with an overview of an intriguing and interdisciplinary field of research. For the first time the mammalian pineal gland, its mode of action and its physiological effects are discussed in a comprehensive, single-authored work.

Author : Georges J. M. Maestroni,Ario Conti,Russel J. Reiter
Publisher : Karger Medical and Scientific Publishers
Page : 182 pages
File Size : 45,8 Mb
Release : 1997-01-01
Category : Science
ISBN : 9783805564397

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Therapeutic Potential of Melatonin by Georges J. M. Maestroni,Ario Conti,Russel J. Reiter Pdf

Over the past decade, the potential of the pineal hormone melatonin as a therapeutic agent in a variety of diseases has been recognized. This book is the first to review the effect of melatonin in sleep disorders, its possible use as an immunoregulatory agent and clinical results obtained in cancer immunotherapy. Several papers are devoted to the pharmacological and molecular characterization of melatonin receptors in a variety of cell types. Other contributions further investigate the immunoenhancing effect of melatonin, such as in viral encephalitis and bacterial infections, and consider possible therapeutic indications. Melatonin is also reported to exert important hematopoietic effects by stimulating the production of novel T helper cell opioid cytokines. Other basic studies introduce new perspectives describing melatonin as a potent free radical scavenger. This book should be read by clinicians working in the fields of sleep disorders, oncology and infectious diseases as well as by scientists active in the field of neuroimmunomodulation. It will also be very useful to all those interested in melatonin as a therapeutic agent.

Author : Franco Fraschini,Russel J. Reiter
Publisher : Springer Science & Business Media
Page : 321 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461537564

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Role of Melatonin and Pineal Peptides in Neuroimmunomodulation by Franco Fraschini,Russel J. Reiter Pdf

Research related to the pineal gland has advanced rapidly in the last three decades since the discovery of its most important hormone, melatonin. This indoleamine has been shown to have a large variety of effects in the organism; the bulk of these actions were initially thought to relate the pineal gland to the reproductive and endocrine systems. It is now apparent, however, that the physiologic interactions of the pineal and its hormones far transcend its control of endocrine function. One field of pineal research that has developed rapidly within the last 5 years has been the demonstration of its relationship to the immune system. Since the pineal gland is part of the central nervous system, these observations generally fall in the category of neuroimmunology, an area that, in its own right, has received a great deal of attention in the last decade. Thus, a NATO Advanced Study Course entitled "Role of Melatonin and Pineal Pep tides in Neuroimmunomodulation" was convened in Erice, Sicily, on June 3-9, 1990. This book is a result of the scientific presentations given at the workshop. The contributions to the book include mini-review articles which summarized the presentations of the invited speakers as well as a selected number of brief communications where the subject matter was in line with the theme of the Advanced Study Course.

Author : Richard G. Stevens,Bary W. Wilson,Larry E. Anderson
Publisher : Unknown
Page : 786 pages
File Size : 51,9 Mb
Release : 1997
Category : Medical
ISBN : UOM:39015041609309

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The Melatonin Hypothesis by Richard G. Stevens,Bary W. Wilson,Larry E. Anderson Pdf

Author : Alexander Birbrair
Publisher : Springer Nature
Page : 155 pages
File Size : 45,5 Mb
Release : 2020-02-06
Category : Science
ISBN : 9783030362140

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Tumor Microenvironments in Organs by Alexander Birbrair Pdf

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more. Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Author : I. Nir,R. J. Reiter,R. J. Wurtman
Publisher : Unknown
Page : 420 pages
File Size : 55,7 Mb
Release : 2015-01-07
Category : Electronic
ISBN : 3709144280

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The Pineal Gland by I. Nir,R. J. Reiter,R. J. Wurtman Pdf

Author : Scott Turner
Publisher : BoD – Books on Demand
Page : 278 pages
File Size : 55,9 Mb
Release : 2022-01-19
Category : Medical
ISBN : 9781839693069

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Central Nervous System Tumors by Scott Turner Pdf

Though the treatment of central nervous system (CNS) tumors has been challenging, new advances have helped us better understand the molecular and genetic makeup of many tumor types, and new chemotherapies and immunotherapies have extended survival in patients with aggressive primary CNS tumors. This book discusses pediatric and adult tumors of the CNS, the classification schemes used to categorize them, advances in surgical techniques, and several important genetic alterations found in these tumors. We hope this book contributes to the reader’s understanding of these tumors and provides the most up-to-date and cutting-edge discoveries in this exciting field.

Author : Yutaka Sawamura,Hiroki Shirato,Nicolas de Tribolet
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709168219

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Intracranial Germ Cell Tumors by Yutaka Sawamura,Hiroki Shirato,Nicolas de Tribolet Pdf

Intracranial germ cell tumors are a group of uncommon neoplasms of the central nervous system. The clinical features and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neurooncologists for decades, the relatively small number of patients seen in any single institution has hampered the important clinical investigation that is so needed. This text is complete with detailed information concerning the epidemiology, pathology, oncological biology, clinical findings, radiology, and treatment options including surgical strategy, radiotherapy, and chemotherapy for this heterogeneous group of neoplasms. The ongoing clinical trials concerning the optimization of therapy are efficiently summarized. An important final segment addresses the late sequelae of therapy which is of great significance since the majority suffering from these tumors are young patients. This first and only book on intracranial germ cell tumors includes excellent and comprehensive data sheets, illustrations, and radiograms. It provides a detailed and outstanding reference source for physicians taking care of patients with intracranial germ cell tumors, and will be a very welcome edition to their reference libraries.

Author : M.A. Hayat
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 53,9 Mb
Release : 2012-12-22
Category : Medical
ISBN : 9789400756816

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Tumors of the Central Nervous System, Volume 10 by M.A. Hayat Pdf

Adding to a vitally important cycle of publications covering the latest research developments in our understanding of neoplasms affecting the human central nervous system, this edition focuses on numerous aspects of pineal, pituitary, and spinal tumors. As with the previous volumes in the series, this latest work addresses a central imperative in cancer research—the need to standardize classifications, written definitions and investigative guidelines in order to achieve a measure of shared objectivity among academics engaged in one of the most important medical endeavors of our era. It brings together the very latest work by oncologists, neurosurgeons, physicians, research scientists, and pathologists, providing the medical community with a wealth of data and results that, taken together, will advance the cause of cancer research. The volume synthesizes work on diagnosis, drug development, and therapeutic approaches that are typically scattered in a variety of journals and books. It features promising recent work in applying molecular genetics to clinical practice and evidence-based therapy, covering molecular profiling of tumors as well as a number of surgical treatments such as resection and radiosurgery. Together with its counterpart publications, it represents a much-needed central resource that will inform and guide future research efforts.