The Relationship Between Adiposity And Coronary Heart Disease Risk Factors Associated With The Insulin Resistance Syndrome In Men And Women
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Disease Control Priorities, Third Edition (Volume 5) by Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent Pdf
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.
Obesity and Cardiovascular Disease by Malcolm K Robinson,Abraham Thomas Pdf
Although cardiovascular disease remains the leading proximate cause of death in the United States, it is now estimated that obesity may be equivalent to smoking as the leading cause of preventable death in America. In light of these statistics, this reference presents our current understanding of the epidemiology, pathology, and genetics of the obe
The Relationship Between Adiposity and Coronary Heart Disease Risk Factors Associated with the Insulin Resistance Syndrome in Men and Women by M. Esther Colwell Pdf
Author : Philip Scott Zeitler,Kristen J. Nadeau Publisher : Springer Science & Business Media Page : 340 pages File Size : 51,9 Mb Release : 2008-12-28 Category : Medical ISBN : 9781597451925
Insulin Resistance by Philip Scott Zeitler,Kristen J. Nadeau Pdf
In the mid 1990s, Drs. Gerald Reaven identified a constellation of clinical findings, known variously as the metabolic syndrome, syndrome X, insulin resistance s- drome or insulin resistance-related disorders, that are associated with an increased risk of heart disease and diabetes. Interest in this topic grew rapidly, culminating in the publication by this series of the book, Insulin Resistance and the Metabolic Syndrome X, edited by Drs. Reaven and Laws in 1999. Since the original publication of that now classic volume, the world’s population has continued to become more obese and sedentary and the prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Today, about one in three children and adolescents in the United States is overweight or obese, and this prevalence approaches one in two among adolescents in certain minority groups. In addition, components of this cardiovascular risk constellation are now being recognized in young adults, adolescents, and even children. Youth are increasingly developing type 2 diabetes, fatty liver disease, hypertriglyceridemia, hypertension, polycystic ovarian syndrome, sleep apnea, orthopedic and psychiatric complications, as well as other complications of obesity and insulin resistance.
Author : Robert H. Eckel Publisher : John Wiley & Sons Page : 238 pages File Size : 44,9 Mb Release : 2010-12-01 Category : Medical ISBN : 9781405181044
Metabolic Risk for Cardiovascular Disease by Robert H. Eckel Pdf
The relationship of metabolic diseases to cardiovascular disease (CVD) is reaching epidemic proportions. This relates mostly to the increasing prevalence of obesity, the metabolic syndrome and type 2 diabetes. This book outlines and addresses the metabolic factors and related diseases that contribute to CVD, including brief introductions to metabolic pathways including lipid and lipoprotein metabolism, macronutrient fuel partitioning, insulin action and body weight regulation. Mechanisms that relate to becoming obese, maintenance of the obese state, the dyslipidemias, and glucose intolerance/diabetes are also addressed, and the importance of interventions that reduce metabolic risk factors and CVD are covered.
Insulin Resistance - ECAB by Gita Ganguly Mukherjee Pdf
The insulin resistance syndrome can be defined as insulin resistance, compensatory hyperinsulinemia, and their associated co-morbidities. Clinically, the term insulin resistance syndrome describes a constellation of abnormalities such as obesity, hypertension, dyslipidemia, type 2 diabetes/hyperglycemia, and coronary artery disease. Insulin is responsible for glucose uptake into the body cells and tissues. The response of the cells to insulin varies from individual to individual. In some individuals, the tissue response to insulin may be diminished. This means that even with adequate levels of insulin, the glucose uptake into the cells and tissues is not optimal. This results in a compensatory over-secretion of insulin from the pancreas. The persistence of high levels of insulin in the blood or hyperinsulinemia is thought to be responsible for some of the abnormalities associated with this condition. However, the exact causal association of the condition with these disorders and the pathophysiology of their evolution are unclear. The most common underlying mechanism proposed is increased free fatty acids from abdominal fat in individuals with central obesity. This leads to deranged insulin signaling, reduced muscular glucose uptake, increased triglyceride synthesis, and hepatic gluconeogenesis. A genetic basis of the disease as well as several other factors such as tumor necrosis factor-α, adiponectin, leptin, Interleukin-6, and some adipokines have also been implicated. Insulin resistance syndrome is of clinical significance because of its association with potentially debilitating conditions that contribute to long-term morbidity and even mortality of the individual. People with insulin resistance syndrome are at an increased risk of developing type 2 diabetes, hypertension, dyslipidemia, myocardial infarction, polycystic ovarian disease, and fatty liver. In this book, we have tried to collate the experiences of the pioneers of this field on the subject and provide the reader a comprehensive view on the topic along with practical management points, which we are sure will benefit the physicians in their clinical practice. The contributors have focused on the condition as is prevalent in our subcontinent and have tried to give an insight on the issues pertaining to the same with a topical flavor.
Williams Textbook of Endocrinology by Shlomo Melmed, MBChB, MACP,Kenneth S. Polonsky, MD,P. Reed Larsen, MD, FRCP,Henry M. Kronenberg, MD Pdf
For more than 65 years, Williams Textbook of Endocrinology has been the gold standard in the field, delivering authoritative guidance on every aspect of adult and pediatric endocrine system disorders. The 13th Edition has been thoroughly updated by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, to bring you state-of-the-art coverage of diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more, all designed to help you provide optimal care to every patient. Bridging the gap between basic science and clinical information, it is an essential, relevant resource for endocrinologists, endocrine surgeons, gynecologists, internists, and pediatricians - any clinician who needs the most reliable coverage available on the diverse features across the spectrum of endocrine disease. Obtain a better understanding of both scientific insight and clinical data from the classic reference that delivers the current information you need in a highly illustrated, user-friendly format. Stay up to date with expanded discussions of autoimmune thyroid diseases, mechanisms, and the appropriate treatment of the ophthalmopathy of Graves' disease; a new section on the interpretation of fine needle aspiration results in patients with thyroid nodules; and new coverage of when and when not to use radioiodine in the treatment of patients with thyroid cancer. Update your knowledge and skills with all-new chapters on Genetics of Endocrine Disease, Endocrinology of Population Health, and Laboratory Techniques for Recognition of Endocrine Disorders. Confidently manage any clinical endocrinopathy you may encounter thanks to new information on recent FDA-approved drugs for pituitary disorders, a new focus on pediatrics, and new content on diabetes, obesity, and appetite control. Benefit from the expertise of dynamic new contributors who offer fresh perspectives throughout.
Peter G. Kopelman,Ian D. Caterson,William H. Dietz
Author : Peter G. Kopelman,Ian D. Caterson,William H. Dietz Publisher : John Wiley & Sons Page : 504 pages File Size : 52,9 Mb Release : 2008-04-15 Category : Medical ISBN : 9781405143660
Clinical Obesity in Adults and Children by Peter G. Kopelman,Ian D. Caterson,William H. Dietz Pdf
Highly Commended in the 2006 British Medical AssociationBook Awards (Endocrinology) This Second Edition brings together more than 20 internationallyrecognized experts in the field to provide a timely review ofcurrent knowledge. The text remains an invaluable resource for allhealthcare professionals involved in the care of patients who areobese. New features of this Second Edition include: Addition of two new co-editors – Professor Bill Dietz,USA and Professor Ian Caterson, Australia Increased number of contributors from around the globe –providing a truly international perspective Includes new information about the causes of obesity, itscomplications and new (and novel) methods of prevention andtreatment Reorganized into sections that address obesity and its socialand cultural aspects, biology, associated diseases, life stages(pediatric and adult), management, and environmental and policyapproaches
Geriatric Diabetes by Medha N. Munshi,Lewis A. Lipsitz Pdf
The number of elderly patients with diabetes is increasing at a significant rate. Responding to this growth, this source serves as a solid arsenal of information on the varying presentations and challenges associated with diabetes in the geriatric patient, and supplies clearly written sections on the screening, diagnosis, and treatment of diabetes
Williams Textbook of Endocrinology E-Book by Henry M. Kronenberg Pdf
In your complex and dynamic field, it can be a struggle to continually integrate the latest scientific and clinical information into your everyday patient care. The 11th Edition of this beloved reference is the solution! Leading authorities provide just the right blend of scientific insight and clinical know-how to help you overcome any clinical challenge. A new full-color, extremely user-friendly format makes reference a snap. And, full-text online access lets you search the contents rapidly from any computer! Chapters bridge the gap between basic science and clinical applications, providing the right context for optimal diagnosis and treatment. Chapters by the leading authorities in endocrinology equip you with authoritative opinions on any challenge you face. New chapters on hormones and athletic performance - neuroendocrine control of appetite and body weight - and HIV/AIDS keep you up to date on these timely topics. New evidence-based screening algorithms and treatment boxes deliver reliable clinical guidance at a glance. New full-color illustrations throughout help you grasp essential concepts easily. Full-text online access lets you search the book instantly on your computer and download images for your next presentation.
Energy Metabolism and Obesity by Patricia A. Donohoue Pdf
This unique and authoritative book presents an up-to-date overview of the many aspects of energy balance and its relationships to disease processes resulting from excess energy consumption and storage. It provides a comprehensive treatment of important research and clinical aspects of energy metabolism and obesity. It will be a valuable resource for endocrinologists, diabetes specialists, internists and family practitioners.
James T. Willerson,Jay N. Cohn,Hein J.J. Wellens,David R. Holmes
Author : James T. Willerson,Jay N. Cohn,Hein J.J. Wellens,David R. Holmes Publisher : Springer Science & Business Media Page : 2877 pages File Size : 54,7 Mb Release : 2007-12-06 Category : Medical ISBN : 9781846287152
Cardiovascular Medicine by James T. Willerson,Jay N. Cohn,Hein J.J. Wellens,David R. Holmes Pdf
This book offers the most up-to-date, user-friendly guidance on the evaluation, diagnosis and medical and surgical treatment of heart and vascular disease. The book and DVD package is designed to provide comprehensive coverage of every aspect of cardiovascular medicine. The book has consistent chapter organization relevant to modern cardiovascular practice, clear design and engaging text. The reader will have all the guidance to diagnose and manage the full range of cardiovascular conditions in one textbook resource, while also benefiting from access to additional video material from the integral DVD-ROM. This includes over 100 individual heart sounds.
Diabetes in Women by Agathocles Tsatsoulis,Jennifer Wyckoff,Florence M. Brown Pdf
Gender differences impact the pathophysiology and clinical burden of diabetes in women. Exploring the complex interplay between gender and diabetes, Diabetes in Women provides a state-of-the-art update from conception to menopause and beyond. Written by experts in the field, Diabetes in Women covers sex differences in cardiometabolic risk, the impact of diabetes on women’s health, diabetes and pregnancy, offspring of the diabetic mother and the disease management of women with diabetes. Chapters include up to date information on cardiometabolic risk in women throughout the lifecycle and the differences between sexes in energy balance and body composition. Prominent authors also explore the impact of poverty and globalization on the emerging epidemic of obesity in developing countries. Designed for primary care and internal medicine physicians, endocrinologists, obstetricians and gynecologists, and trainees and basic scientists in these areas, Diabetes in Women is an invaluable resource and important contribution to the field.
Textbook of Nephro-Endocrinology by Ajay K. Singh,Gordon H. Williams Pdf
Textbook of Nephro-Endocrinology, Second Edition, continues to be the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism. Changes to this edition include new chapters focused on hypercalcemia/hypocalcemia and the interaction of dialysis, chronic renal disease, and endocrine diseases. All chapters have been updated to include more preclinical data and more tables and schema that help translate this data into clinical recommendations. The section on hormones and renal insufficiency discusses insulin/diabetes, growth hormone, sex steroids, thyroid hormone, acid–base disturbances, and pregnancy. Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems Offers clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field Features new and updated chapters that include more tables and schema to help translate preclinical data into clinical recommendations